NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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Dimethoxycurcumin
CAS:160096-59-3
Dimethoxycurcumin is a stable curcumin analog causing epigenetic shifts in leukemia cells, affecting gene expression.
Formula:
C23H24O6
Purity:
96.05%
Color and Shape:
Solid
Molecular weight:
396.43
Ref: TM-T19853
| 5mg | 50.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 137.00 € | ||
| 50mg | 232.00 € | ||
| 100mg | 339.00 € | ||
| 200mg | 483.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
GGTI 2147
CAS:191102-87-1
GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.
Formula:
C28H30N4O3
Purity:
99.32%
Color and Shape:
Solid
Molecular weight:
470.56
Ref: TM-T25450
| 1mg | 486.00 € | ||
| 5mg | 1,091.00 € | ||
| 10mg | 1,421.00 € | ||
| 25mg | 1,838.00 € | ||
| 50mg | 2,209.00 € | ||
| 100mg | 2,877.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
RIP1 kinase inhibitor 4
CAS:2919836-00-1
RIP1 Kinase Inhibitor 4 (Compound 3) is an effective inhibitor of RIP1K, exhibiting an EC50 …
Formula:
C23H23N5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
369.46
Ref: TM-T79041
| 25mg | 1,688.00 € | ||
| 50mg | 2,225.00 € | ||
| 100mg | 2,897.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Demethyleneberberine chloride
CAS:16705-03-6
Demethyleneberberine chloride, a natural mitochondria-targeted antioxidant, mitigates colitis in mice and suppresses inflammatory responses by …
Formula:
C19H18ClNO4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
359.8
Ref: TM-T78095
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 10 Mar 2025
ACHP Hydrochloride
CAS:406209-26-5
ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an …
Formula:
C21H25ClN4O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
400.9
Ref: TM-T10237
| 1mg | 66.00 € | ||
| 5mg | 143.00 € | ||
| 10mg | 225.00 € | ||
| 25mg | 371.00 € | ||
| 50mg | 534.00 € | ||
| 100mg | 768.00 € | ||
| 500mg | 1,515.00 € | ||
| 1mL*10mM (DMSO) | 158.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
IR-Crizotinib
CAS:2387927-74-2
IR-Crizotinib is a conjugate of the near-infrared dye IR-786 and Crizotinib, an NF-κB-inducing kinase (NIK) …
Formula:
C53H57Cl2FIN7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1024.88
Ref: TM-T82049
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 10 Mar 2025
Ginsenoside Rk1
CAS:494753-69-4
Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.
Formula:
C42H70O12
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
767
Ref: TM-T4S1499
| 5mg | 91.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
GSK840
CAS:2361146-30-5
GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the …
Formula:
C21H23N3O3
Purity:
99.48%
Color and Shape:
Solid
Molecular weight:
365.43
Ref: TM-T11501
| 1mg | 37.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 112.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 278.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
PROTAC IRAK4 degrader-8
CAS:2911615-06-8
PROTAC IRAK4 Degrader-8 (Compound 2) is a PROTAC designed to target IRAK4 with an IC50 …
Formula:
C43H50ClF2N11O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
874.38
Ref: TM-T79097
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 10 Mar 2025
NLRP3-IN-9
CAS:88039-46-7
NLRP3-IN-9 (INF-4E) irreversibly inhibits NLRP3 ATPase, caspase-1, and prevents pyroptosis in THP-1 cells.
Formula:
C12H13ClO3
Purity:
98.51%
Color and Shape:
Solid
Molecular weight:
240.68
Ref: TM-T28178
| 1mg | 41.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 241.00 € | ||
| 50mg | 392.00 € | ||
| 100mg | 622.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
NLRP3 agonist 1
CAS:2454019-69-1
Vatalanib hydrochloride (PTK787 hydrochloride) is a VEGF inhibitor that reduces the number and area of …
Formula:
C15H16N6
Purity:
99.01%
Color and Shape:
Liquid
Molecular weight:
280.33
Ref: TM-T81668
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 10 Mar 2025
NF-κB-IN-13
CAS:117596-92-6
NF-κB-IN-13 (compound 12) markedly suppresses LPS-induced NF-κB activation and NO synthesis in RAW264.7 macrophages, exhibiting …
Formula:
C20H20O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
340.37
Ref: TM-T79999
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 10 Mar 2025
Antiproliferative agent-22
CAS:1374305-45-9
Antiproliferative agent-22 is an anticancer compound that shows antiproliferative activity on MCF-7, MDA-MB-231 and MDA-MB-468 …
Formula:
C17H13N3O3
Purity:
99.20% - 99.30%
Color and Shape:
Liquid
Molecular weight:
307.3
Ref: TM-T85699
| 1mg | 197.00 € | ||
| 5mg | 486.00 € | ||
| 10mg | 682.00 € | ||
| 25mg | 1,064.00 € | ||
| 50mg | 1,468.00 € | ||
| 100mg | 1,879.00 € |
Estimated delivery in United States, on Monday 7 Apr 2025
Sabialimon P
CAS:2267333-96-8
Sabialimon P (compound 16), with an IC50 of 18.12 μM, functions as a NO release …
Formula:
C31H50O4
Color and Shape:
Liquid
Molecular weight:
486.73
Ref: TM-T200238
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 7 Apr 2025
GTCpFE
CAS:1588866-45-8
GTCpFE, a compound synthesized from Dimethyl fumarate (DMF) and Aspirin (ASA), inhibits IKKα/β in the …
Formula:
C22H20O8
Color and Shape:
Liquid
Molecular weight:
412.39
Ref: TM-T200141
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 7 Apr 2025
SBI-0640726
CAS:1321827-45-5
SBI-0640726, an eIF4G1 inhibitor, exhibits antiproliferative activity against melanoma. It disrupts the eIF4F translation initiation …
Formula:
C23H15ClN2O2
Color and Shape:
Liquid
Molecular weight:
386.83
Ref: TM-T89836
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 7 Apr 2025
HOIPIN-8 sodium
CAS:2519537-70-1
HOIPIN-8 sodium is a LUBAC inhibitor for the study of inflammatory and immune diseases.
Formula:
C23H15F2N4NaO3
Color and Shape:
Liquid
Molecular weight:
456.38
Ref: TM-T62826
| 1mg | 113.00 € | ||
| 5mg | 269.00 € | ||
| 10mg | 461.00 € | ||
| 25mg | 884.00 € | ||
| 50mg | 1,383.00 € | ||
| 100mg | 2,190.00 € |
Estimated delivery in United States, on Monday 7 Apr 2025
UBS109
CAS:1258513-40-4
UBS109, a curcumin analog, is a DNA demethylating agent in pancreatic cancer that promotes osteoblast …
Formula:
C18H17N3O
Color and Shape:
Liquid
Molecular weight:
291.35
Ref: TM-T88314
| 2mg | 39.00 € | ||
| 5mg | 58.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 167.00 € | ||
| 50mg | 256.00 € | ||
| 100mg | 391.00 € | ||
| 200mg | 567.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Monday 7 Apr 2025
TNFα activity modulator 3
CAS:2248726-53-4
TNFα Activity Modulator 3 (example 6) is a molecule that regulates TNF activity by inhibiting …
Formula:
C27H24F2N6O2
Color and Shape:
Liquid
Molecular weight:
502.52
Ref: TM-T89932
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 7 Apr 2025
TBK1/IKKε-IN-1
CAS:2058264-32-5
TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of <100 nM).
Formula:
C28H26N4O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
498.53
Ref: TM-T13097
| 25mg | 2,238.00 € | ||
| 50mg | 2,974.00 € | ||
| 100mg | 4,021.00 € |
Estimated delivery in United States, on Monday 7 Apr 2025
