NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Read more
Biricodar dicitrate
CAS:174254-13-8
Biricodar dicitrate (VX-710) is a potent MDR inhibitor with no anticancer activity and can be …
Formula:
C46H57N3O21
Purity:
98.67%
Color and Shape:
Liquid
Molecular weight:
987.95
Ref: TM-T67790
| 1mg | 493.00 € | ||
| 5mg | 1,086.00 € | ||
| 25mg | 1,825.00 € | ||
| 50mg | 2,209.00 € | ||
| 100mg | 2,890.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
BAY32-5915
CAS:1571-30-8
BAY32-5915 is a selective inhibitor of IKKalpha.
Formula:
C10H7NO3
Purity:
96.48% - 97.00%
Color and Shape:
Yellow Crystalline Powder
Molecular weight:
189.17
Ref: TM-T20770
| 100mg | 46.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
NLRP3-IN-10
CAS:2641826-39-1
NLRP3-IN-10 (ZVN26391) is a strong NLRP3 inhibitor, IC50 251.1 nM, that reduces IL-1β and ASC …
Formula:
C17H14BrFO3
Purity:
99.63%
Color and Shape:
Liquid
Molecular weight:
365.19
Ref: TM-T61392
| 5mg | 46.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 305.00 € | ||
| 200mg | 454.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
TRAF-STOP inhibitor 6877002
CAS:433249-94-6
TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.
Formula:
C17H17NO
Purity:
99.65%
Color and Shape:
Solid
Molecular weight:
251.32
Ref: TM-T17157
| 10mg | 42.00 € | ||
| 25mg | 85.00 € | ||
| 50mg | 140.00 € | ||
| 100mg | To inquire | ||
| 200mg | To inquire | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
Emlenoflast sodium
CAS:2380032-29-9
Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 …
Formula:
C19H24N4NaO3S
Color and Shape:
Liquid
Molecular weight:
411.47
Ref: TM-T9222L
| 2mg | To inquire | ||
| 5mg | 906.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Monday 24 Feb 2025
CAY10575
CAS:916985-21-2
CAY10575 (IKK2-IN-3) is a potent IKK2 inhibitor with potential anti-inflammatory activity for the study of …
Formula:
C22H21N3O6S2
Color and Shape:
Solid
Molecular weight:
487.55
Ref: TM-T26957
| 1mg | 92.00 € | ||
| 5mg | 341.00 € | ||
| 10mg | 642.00 € | ||
| 25mg | 1,380.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
SZM-1209
CAS:2919801-86-6
SZM-1209 is a potent and specific RIPK1 inhibitor with oral activity, displaying a dissociation constant …
Formula:
C31H29F5N4O5S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
696.71
Ref: TM-T73382
| 1mg | 184.00 € | ||
| 5mg | 726.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
RIPK1-IN-9
CAS:2682889-57-0
RIPK1-IN-9, a potent dihydronaphthone, selectively inhibits RIPK1 with IC50 of 2 nM (U937) and 1.3 …
Formula:
C26H25FN6O2
Purity:
98.7%
Color and Shape:
Liquid
Molecular weight:
472.51
Ref: TM-T63055
| 1mg | 335.00 € | ||
| 5mg | 804.00 € | ||
| 10mg | 1,110.00 € | ||
| 25mg | 1,654.00 € | ||
| 50mg | 2,224.00 € | ||
| 100mg | 2,989.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
HS271
CAS:2410393-15-4
HS271 is a selective, highly potent and orally active IRAK4 inhibitor (IC50= 7.2 μM).
Formula:
C21H24F3N5O2
Purity:
98.12%
Color and Shape:
Solid
Molecular weight:
435.44
Ref: TM-T37082
| 1mg | 60.00 € | ||
| 2mg | 87.00 € | ||
| 5mg | 130.00 € | ||
| 10mg | 204.00 € | ||
| 25mg | 354.00 € | ||
| 50mg | 491.00 € | ||
| 100mg | 670.00 € | ||
| 200mg | 902.00 € | ||
| 1mL*10mM (DMSO) | 144.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
Edasalonexent
CAS:1204317-86-1
Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor for the improvement of Duchenne muscular dystrophy.
Formula:
C31H42N2O3
Purity:
100% - 98.69%
Color and Shape:
Solid
Molecular weight:
490.68
Ref: TM-T15198
| 1mg | 98.00 € | ||
| 2mg | 144.00 € | ||
| 5mg | 233.00 € | ||
| 10mg | 374.00 € | ||
| 25mg | 672.00 € | ||
| 50mg | 1,056.00 € | ||
| 1mL*10mM (DMSO) | 252.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
IKK2-IN-4
CAS:354811-10-2
IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 …
Formula:
C12H11N3O2S
Purity:
100%
Color and Shape:
Liquid
Molecular weight:
261.3
Ref: TM-T36524
| 1mg | 302.00 € | ||
| 5mg | 736.00 € | ||
| 10mg | 1,009.00 € | ||
| 25mg | 1,523.00 € | ||
| 50mg | 2,037.00 € | ||
| 100mg | 2,775.00 € | ||
| 200mg | 3,662.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
Bay 65-1942 free base
CAS:600734-02-9
Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.
Formula:
C22H25N3O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
395.45
Ref: TM-T10472L
| 25mg | 1,410.00 € | ||
| 50mg | 1,845.00 € | ||
| 100mg | 2,329.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
Bay 65-1942 hydrochloride
CAS:600734-06-3
Bay 65-1942 hydrochloride is an inhibitor of ATP-competitive and selective IKKβ.
Formula:
C22H26ClN3O4
Color and Shape:
Solid
Molecular weight:
431.91
Ref: TM-T14508
| 2mg | 115.00 € | ||
| 5mg | 185.00 € | ||
| 25mg | 605.00 € | ||
| 50mg | 793.00 € | ||
| 100mg | 1,236.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
IRAK4-IN-20
CAS:1931994-80-7
IRAK4-IN-20 is a potent and orally active IRAK4 inhibitor (IC50:3.55 nM).
Formula:
C22H25F3N4O3
Purity:
97.32%
Color and Shape:
Liquid
Molecular weight:
450.45
Ref: TM-T62714
| 1mg | 182.00 € | ||
| 5mg | 417.00 € | ||
| 10mg | 612.00 € | ||
| 25mg | 922.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
B022
CAS:1202764-53-1
B022 is an NF-κB-induced kinase (NIK) inhibitor that protects the liver from inflammation and injury …
Formula:
C19H16ClN5OS
Purity:
99.74%
Color and Shape:
Solid
Molecular weight:
397.88
Ref: TM-T14491
| 1mg | 74.00 € | ||
| 5mg | 163.00 € | ||
| 10mg | 231.00 € | ||
| 25mg | 391.00 € | ||
| 50mg | 572.00 € | ||
| 100mg | 734.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
Armepavine
CAS:524-20-9
Armepavine (R-Armepavine) exerted both in vitro and in vivo antifibrotic effects in rats, with inhibition …
Formula:
C19H23NO3
Purity:
95.00%
Color and Shape:
Solid
Molecular weight:
313.39
Ref: TM-T3775
| 5mg | 259.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
JC124
CAS:1638611-48-9
JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.
Formula:
C17H19ClN2O4S
Purity:
98.54%
Color and Shape:
Solid
Molecular weight:
382.86
Ref: TM-T25548
| 1mg | 62.00 € | ||
| 5mg | 142.00 € | ||
| 10mg | 220.00 € | ||
| 25mg | 368.00 € | ||
| 50mg | 524.00 € | ||
| 100mg | 710.00 € | ||
| 200mg | 912.00 € | ||
| 1mL*10mM (DMSO) | 156.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
CHPG sodium salt
CAS:1303993-73-8
CHPG sodium salt is a selective agonist of mGluR5 and activates the ERK and Akt …
Formula:
C8H7ClNNaO3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
223.59
Ref: TM-T10808
| 5mg | 47.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
RIP1 kinase inhibitor 7
CAS:2428401-23-2
RIP1 Kinase Inhibitor 7 (Compound 41) serves as a potent inhibitory agent for receptor interacting …
Formula:
C20H20FN3O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
337.39
Ref: TM-T79044
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
NF-κB-IN-8
CAS:2924565-59-1
NF-κB-IN-8 is a competitive antagonist of LPS for MD-2 binding, and it impedes the expression …
Formula:
C24H21N3O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
399.44
Ref: TM-T74799
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
