IκB/IKK
The IκB/IKK complex is a key regulator of the NF-κB signaling pathway, which controls the expression of genes involved in immune responses, inflammation, and cell survival. IκB proteins inhibit NF-κB activity by sequestering it in the cytoplasm, while IKKs phosphorylate IκB, leading to its degradation and the activation of NF-κB. Dysregulation of the IκB/IKK pathway is linked to chronic inflammation, cancer, and autoimmune diseases. At CymitQuimica, we provide a selection of high-quality IκB/IKK modulators to support your research in signal transduction, inflammation, and therapeutic development.
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IMD-0354
CAS:978-62-1
IMD-0354 (IKK2 Inhibitor V) is an IKKβ inhibitor and inhibits IκBα phosphorylation in NF-κB pathway.
Formula:
C15H8ClF6NO2
Purity:
99.56% - 99.71%
Color and Shape:
Solid
Molecular weight:
383.67
Ref: TM-T6141
| 2mg | 47.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 91.00 € | ||
| 25mg | 160.00 € | ||
| 50mg | 217.00 € | ||
| 100mg | 304.00 € | ||
| 500mg | 737.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
BOT-64
CAS:113760-29-5
BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's …
Formula:
C15H15NO2S
Purity:
99.73%
Color and Shape:
Solid
Molecular weight:
273.35
Ref: TM-T8705
| 1mg | 51.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 328.00 € | ||
| 50mg | 502.00 € | ||
| 100mg | 676.00 € | ||
| 200mg | 909.00 € | ||
| 1mL*10mM (DMSO) | 104.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
JTP 0819958 - HOIPIN-1
JTP-0819958: LUBAC inhibitor, IC50 2.8 μM; blocks NF-kB activation in vitro.
Formula:
C17H13NaO4
Purity:
95.08%
Color and Shape:
Solid
Molecular weight:
304.27
Ref: TM-T8951
| 1mg | 39.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 99.00 € | ||
| 25mg | 219.00 € | ||
| 50mg | 354.00 € | ||
| 100mg | 517.00 € | ||
| 500mg | 1,138.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
BMS-345541
CAS:445430-58-0
BMS-345541 (IKK Inhibitor III) is a highly selective inhibitor of the catalytic subunits of IKK-2 …
Formula:
C14H17N5
Purity:
100% - 98.74%
Color and Shape:
Solid
Molecular weight:
255.32
Ref: TM-T6326
| 1mg | 38.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 163.00 € | ||
| 50mg | 260.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
NF-κB-IN-1
CAS:1227098-15-8
NF-κB-IN-1 (1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-) is a potent NF-κB signaling pathway
Formula:
C31H30O8
Purity:
99.03%
Color and Shape:
Solid
Molecular weight:
530.57
Ref: TM-T9105
| 1mg | 164.00 € | ||
| 5mg | 337.00 € | ||
| 10mg | 543.00 € | ||
| 25mg | 887.00 € | ||
| 50mg | 1,201.00 € | ||
| 100mg | 1,623.00 € | ||
| 1mL*10mM (DMSO) | 392.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
IKK 16
CAS:873225-46-8
IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK …
Formula:
C28H29N5OS
Purity:
99.61%
Color and Shape:
Solid
Molecular weight:
483.63
Ref: TM-T6176
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 137.00 € | ||
| 25mg | 240.00 € | ||
| 50mg | 398.00 € | ||
| 100mg | 593.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
BMS-345541 hydrochloride
CAS:547757-23-3
BMS-345541 hydrochloride is a selective IKK inhibitor (IKK2 and IKK1 with IC50 of 0.3 μM …
Formula:
C14H18ClN5
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
291.78
Ref: TM-T8542
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 220.00 € | ||
| 50mg | 368.00 € | ||
| 100mg | 551.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
GS143
CAS:916232-21-8
GS143 inhibits IκBα ubiquitination (IC50=5.2μM), suppresses NF-κB, and has anti-asthma properties without hindering proteasomes.
Formula:
C28H19FN2O4
Purity:
99.72%
Color and Shape:
Solid
Molecular weight:
466.46
Ref: TM-T25465
| 2mg | 37.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | 164.00 € | ||
| 50mg | 250.00 € | ||
| 100mg | 364.00 € | ||
| 200mg | 528.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
MRT67307 HCl (1190378-57-4(free base))
MRT67307 is a kinase inhibitor of TBK1, MARK1-4, IKKε, and NUAK1 (IC50: 19, 27-52, 160, …
Formula:
C26H37ClN6O2
Purity:
98.19%
Color and Shape:
Solid
Molecular weight:
501.07
Ref: TM-T5162
| 1mg | 43.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 100.00 € | ||
| 25mg | 223.00 € | ||
| 50mg | 402.00 € | ||
| 100mg | 503.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
CAY10575
CAS:916985-21-2
CAY10575 (IKK2-IN-3) is a potent IKK2 inhibitor with potential anti-inflammatory activity for the study of …
Formula:
C22H21N3O6S2
Color and Shape:
Solid
Molecular weight:
487.55
Ref: TM-T26957
| 1mg | 92.00 € | ||
| 5mg | 341.00 € | ||
| 10mg | 642.00 € | ||
| 25mg | 1,380.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
Bay 65-1942 free base
CAS:600734-02-9
Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.
Formula:
C22H25N3O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
395.45
Ref: TM-T10472L
| 25mg | 1,410.00 € | ||
| 50mg | 1,845.00 € | ||
| 100mg | 2,329.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
Armepavine
CAS:524-20-9
Armepavine (R-Armepavine) exerted both in vitro and in vivo antifibrotic effects in rats, with inhibition …
Formula:
C19H23NO3
Purity:
95.00%
Color and Shape:
Solid
Molecular weight:
313.39
Ref: TM-T3775
| 5mg | 259.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
Bay 65-1942 hydrochloride
CAS:600734-06-3
Bay 65-1942 hydrochloride is an inhibitor of ATP-competitive and selective IKKβ.
Formula:
C22H26ClN3O4
Color and Shape:
Solid
Molecular weight:
431.91
Ref: TM-T14508
| 2mg | 115.00 € | ||
| 5mg | 185.00 € | ||
| 25mg | 605.00 € | ||
| 50mg | 793.00 € | ||
| 100mg | 1,236.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
IKK2-IN-4
CAS:354811-10-2
IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 …
Formula:
C12H11N3O2S
Purity:
100%
Color and Shape:
Liquid
Molecular weight:
261.3
Ref: TM-T36524
| 1mg | 302.00 € | ||
| 5mg | 736.00 € | ||
| 10mg | 1,009.00 € | ||
| 25mg | 1,523.00 € | ||
| 50mg | 2,037.00 € | ||
| 100mg | 2,775.00 € | ||
| 200mg | 3,662.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
GSK319347A
CAS:862812-98-4
GSK319347A is a dual inhibitor of TBK1 and IKKε that inhibits IKK2 and can be …
Formula:
C22H19N3O5S2
Purity:
98.42%
Color and Shape:
Solid
Molecular weight:
469.53
Ref: TM-T15558
| 1mg | 74.00 € | ||
| 5mg | 150.00 € | ||
| 10mg | 251.00 € | ||
| 25mg | 526.00 € | ||
| 50mg | 893.00 € | ||
| 100mg | 1,204.00 € | ||
| 1mL*10mM (DMSO) | 338.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
BAY32-5915
CAS:1571-30-8
BAY32-5915 is a selective inhibitor of IKKalpha.
Formula:
C10H7NO3
Purity:
96.48% - 97.00%
Color and Shape:
Yellow Crystalline Powder
Molecular weight:
189.17
Ref: TM-T20770
| 100mg | 46.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
IKK-IN-1
CAS:406211-06-1
IKK-IN-1 is an inhibitor of IKK.
Formula:
C22H26ClN3O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
431.91
Ref: TM-T11633
| 25mg | 1,030.00 € | ||
| 50mg | 1,351.00 € | ||
| 100mg | 2,040.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
(Rac)-BAY-985
CAS:2101925-20-4
(Rac)-BAY-985 is a potent, ATP-competitive and selective inhibitor of TBK1(IC50 of 1.5 nM),with antitumor efficacy.
Formula:
C27H30F3N9O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
553.58
Ref: TM-T12659
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
TBK1-IN-1
TBK1-IN-1 is a TANK-binding kinase 1 inhibitor with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 …
Formula:
C27H37N7O2
Purity:
99.91%
Color and Shape:
Solid
Molecular weight:
491.63
Ref: TM-T73322
| 1mg | 143.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
ACHP Hydrochloride
CAS:406209-26-5
ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an …
Formula:
C21H25ClN4O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
400.9
Ref: TM-T10237
| 1mg | 66.00 € | ||
| 5mg | 143.00 € | ||
| 10mg | 225.00 € | ||
| 25mg | 371.00 € | ||
| 50mg | 534.00 € | ||
| 100mg | 768.00 € | ||
| 500mg | 1,515.00 € | ||
| 1mL*10mM (DMSO) | 158.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
