IκB/IKK
The IκB/IKK complex is a key regulator of the NF-κB signaling pathway, which controls the expression of genes involved in immune responses, inflammation, and cell survival. IκB proteins inhibit NF-κB activity by sequestering it in the cytoplasm, while IKKs phosphorylate IκB, leading to its degradation and the activation of NF-κB. Dysregulation of the IκB/IKK pathway is linked to chronic inflammation, cancer, and autoimmune diseases. At CymitQuimica, we provide a selection of high-quality IκB/IKK modulators to support your research in signal transduction, inflammation, and therapeutic development.
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BAY-985
CAS:2409479-29-2
BAY-985: potent oral TBK1/IKKε inhibitor; IC50s: TBK1 (2/30 nM), IKKε (2 nM); has antitumor properties.
Formula:
C27H30F3N9O
Purity:
99.62%
Color and Shape:
Solid
Molecular weight:
553.58
Ref: TM-T10477
| 1mg | 172.00 € | ||
| 5mg | 354.00 € | ||
| 10mg | 567.00 € | ||
| 25mg | 905.00 € | ||
| 50mg | 1,225.00 € | ||
| 100mg | 1,644.00 € | ||
| 1mL*10mM (DMSO) | 430.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
TBK1/IKKε-IN-2
CAS:1292310-49-6
TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.
Formula:
C26H27N5O3
Purity:
98.89%
Color and Shape:
Solid
Molecular weight:
457.52
Ref: TM-T15559
| 1mg | 92.00 € | ||
| 5mg | 188.00 € | ||
| 10mg | 305.00 € | ||
| 25mg | 487.00 € | ||
| 50mg | 660.00 € | ||
| 100mg | 847.00 € | ||
| 1mL*10mM (DMSO) | 188.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Vinpocetine
CAS:42971-09-5
Vinpocetine (RGH-4405) is a selective inhibitor of cyclic GMP phosphodiesterase (PDE).
Formula:
C22H26N2O2
Purity:
99.98%
Color and Shape:
White Crystalline Solid
Molecular weight:
350.45
Ref: TM-T0167
| 25mg | 35.00 € | ||
| 50mg | 48.00 € | ||
| 100mg | 60.00 € | ||
| 200mg | 80.00 € | ||
| 500mg | 144.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
IMD-0560
CAS:439144-66-8
IMD-0560 is a novel inhibitor of IκB kinase β.
Formula:
C15H8BrF6NO2
Purity:
99.51%
Color and Shape:
Solid
Molecular weight:
428.12
Ref: TM-T15564
| 1mg | 44.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 139.00 € | ||
| 25mg | 245.00 € | ||
| 50mg | 366.00 € | ||
| 100mg | 504.00 € | ||
| 200mg | 692.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
MRT67307
CAS:1190378-57-4
Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy.
Formula:
C26H36N6O2
Purity:
99.25% - 99.79%
Color and Shape:
Solid
Molecular weight:
464.6
Ref: TM-T0097
| 1mg | 40.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 125.00 € | ||
| 25mg | 240.00 € | ||
| 50mg | 462.00 € | ||
| 100mg | 657.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
ACHP
CAS:406208-42-2
ACHP (IKK-2 Inhibitor VIII) is a novel selective and potent IKK inhibitor with inhibitory effects …
Formula:
C21H24N4O2
Purity:
98.66%
Color and Shape:
Solid
Molecular weight:
364.44
Ref: TM-T22021
| 1mg | 52.00 € | ||
| 5mg | 106.00 € | ||
| 10mg | 159.00 € | ||
| 25mg | 255.00 € | ||
| 50mg | 373.00 € | ||
| 100mg | 635.00 € | ||
| 200mg | 1,035.00 € | ||
| 500mg | 2,072.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Cudraflavone B
CAS:19275-49-1
Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in …
Formula:
C25H24O6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
420.45
Ref: TM-TN3726
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Physalin O
CAS:120849-18-5
Physalin O has anti-inflammatory properties, binds with GSH, and inhibits NO production.
Formula:
C28H32O10
Purity:
98%
Color and Shape:
Solid
Molecular weight:
528.554
Ref: TM-TN4779
| 5mg | 855.00 € | ||
| 1mL*10mM (DMSO) | 1,301.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Goshonoside F5
CAS:90851-28-8
Goshonoside F5 has anti-inflammatory activity, it significantly inhibits the pro-inflammatory response induced by LPS, both …
Formula:
C32H54O13
Purity:
98%
Color and Shape:
Solid
Molecular weight:
646.771
Ref: TM-TN4162
| 1mg | 361.00 € | ||
| 5mg | 1,776.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Isophysalin A
CAS:1363398-67-7
Isophysalin A exhibits anti-inflammatory activitiy, it exhibits conjugating abilities with glutathione and also shows significant …
Formula:
C28H30O10
Purity:
98%
Color and Shape:
Solid
Molecular weight:
526.53
Ref: TM-TN4318
| 5mg | 817.00 € | ||
| 1mL*10mM (DMSO) | 1,235.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Selinidin
CAS:19427-82-8
Selinidin decreases phosphorylation of phospholipase C-gamma1, p38 mitogen-activated protein kinase, and IkappaB-alpha upon FcepsilonRI stimulation.
Formula:
C19H20O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
328.364
Ref: TM-TN4986
| 5mg | 513.00 € | ||
| 1mL*10mM (DMSO) | 522.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
TBK1/IKKε-IN-5
CAS:1893397-65-3
TBK1/IKKε-IN-5 is a dual TBK1 and IKKε inhibitor(IC50 of 1 nM and 5.6 nM, respectively).
Formula:
C28H31N7O3
Purity:
98.77%
Color and Shape:
Solid
Molecular weight:
513.59
Ref: TM-T7951
| 1mg | 94.00 € | ||
| 5mg | 192.00 € | ||
| 10mg | 284.00 € | ||
| 25mg | 454.00 € | ||
| 50mg | 620.00 € | ||
| 100mg | 883.00 € | ||
| 200mg | 1,188.00 € | ||
| 1mL*10mM (DMSO) | 235.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
BX795
CAS:702675-74-9
BX795 selectively inhibits PDK1 (IC50: 6 nM), 140x over PKA, 1600x over PKC, 100x over …
Formula:
C23H26IN7O2S
Purity:
98% - 99.57%
Color and Shape:
Solid
Molecular weight:
591.47
Ref: TM-T1830
| 5mg | 59.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 210.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 513.00 € | ||
| 200mg | 740.00 € | ||
| 500mg | 1,121.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC
CAS:4815-35-4
2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC is Inhibitior of IKKβ.
Formula:
C11H10N2OS
Purity:
99.48%
Color and Shape:
Solid
Molecular weight:
218.27
Ref: TM-T8910
| 5mg | 35.00 € | ||
| 10mg | 49.00 € | ||
| 25mg | 85.00 € | ||
| 50mg | 113.00 € | ||
| 100mg | 169.00 € | ||
| 200mg | 246.00 € | ||
| 1mL*10mM (DMSO) | 42.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
MLN120B
CAS:783348-36-7
MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).
Formula:
C19H15ClN4O2
Purity:
98.92%
Color and Shape:
Solid
Molecular weight:
366.8
Ref: TM-TQ0306
| 1mg | 49.00 € | ||
| 2mg | 70.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 160.00 € | ||
| 25mg | 329.00 € | ||
| 50mg | 567.00 € | ||
| 100mg | 777.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
AZD3264
CAS:1609281-86-8
AZD3264 is a new type IKK2 inhibitor.
Formula:
C21H23N5O4S
Purity:
98.98% - 99.17%
Color and Shape:
Solid
Molecular weight:
441.5
Ref: TM-T6771
| 1mg | 52.00 € | ||
| 2mg | 70.00 € | ||
| 5mg | 103.00 € | ||
| 10mg | 160.00 € | ||
| 25mg | 311.00 € | ||
| 50mg | 502.00 € | ||
| 100mg | 805.00 € | ||
| 500mg | 1,605.00 € | ||
| 1mL*10mM (DMSO) | 114.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Dehydrocostus Lactone
CAS:477-43-0
Dehydrocostus Lactone ((-)-Dehydrocostus lactone) shows anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties.
Formula:
C15H18O2
Purity:
99.86% - 99.98%
Color and Shape:
Solid
Molecular weight:
230.3
Ref: TM-T2833
| 5mg | 47.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 126.00 € | ||
| 50mg | 202.00 € | ||
| 100mg | 311.00 € | ||
| 500mg | 750.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
INH14
CAS:200134-22-1
INH14 is a novel inhibitor of the IKKα/β-dependent TLR inflammatory response (IC50s: 8.97/3.59 μM for …
Formula:
C15H16N2O
Purity:
95.41%
Color and Shape:
Solid
Molecular weight:
240.3
Ref: TM-T5209
| 2mg | 38.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 84.00 € | ||
| 25mg | 120.00 € | ||
| 50mg | 210.00 € | ||
| 100mg | 313.00 € | ||
| 200mg | 452.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
GSK8612
CAS:2361659-62-1
GSK8612 is a highly selective and potent inhibitor of Tank-binding Kinase-1 (TBK1, pIC50: 6.8) .
Formula:
C17H17BrF3N7O2S
Purity:
99.46% - ≥98%
Color and Shape:
Solid
Molecular weight:
520.33
Ref: TM-T5540
| 1mg | 47.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 131.00 € | ||
| 25mg | 215.00 € | ||
| 50mg | 378.00 € | ||
| 100mg | 567.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
SC-514
CAS:354812-17-2
SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent …
Formula:
C9H8N2OS2
Purity:
100% - 99.88%
Color and Shape:
Solid
Molecular weight:
224.3
Ref: TM-T2118
| 5mg | 35.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 87.00 € | ||
| 50mg | 114.00 € | ||
| 100mg | 170.00 € | ||
| 500mg | 430.00 € | ||
| 1mL*10mM (DMSO) | 37.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
