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CCR

CCR

C-C chemokine receptors (CCRs) are a group of GPCRs that respond to chemokines, which are signaling molecules that guide the migration of immune cells to sites of inflammation or infection. CCRs play crucial roles in immune responses, inflammation, and the development of various diseases, including autoimmune disorders and cancer. Modulation of CCR activity is being explored as a therapeutic strategy for conditions such as rheumatoid arthritis, multiple sclerosis, and HIV infection. At CymitQuimica, we provide a range of high-quality CCR modulators to support your research in immunology, inflammation, and therapeutic development.

Found 165 products for "CCR".

products per page.
  • TAK-661

    CAS:
    TAK-661 is an inhibitor of eosinophil chemotaxis (eosinophil chemotaxis) that significantly alleviates late-phase bronchoconstriction while inhibiting the proliferation of eosinophils in bronchoalveolar lavage (BAL) and their infiltration into the airway walls.
    Formula:C13H21N5O3S
    Color and Shape:Solid
    Molecular weight:327.40
  • Ophiobolin C

    CAS:
    inhibitor of human CCR5 binding to HIV-1 gp120
    Formula:C25H38O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:386.5674
  • LMD-902

    CAS:
    LMD-902 is an analog of LMD-009 and acts as a CCR8 agonist with an EC50 of 15 nM. It exhibits excellent binding affinity, which is reliant on crucial residues such as PheVI:16. LMD-902 can be utilized in research for inflammatory conditions like bronchial asthma and central nervous system diseases such as multiple sclerosis.
    Formula:C28H34N2O6S
    Molecular weight:526.65
  • CCR1 antagonist 13

    CAS:
    CCR1 antagonist13 is a selective small molecule antagonist of CCR1.
    Formula:C25H27ClFN3O4
    Color and Shape:Solid
    Molecular weight:487.95
  • AZD-5672

    CAS:
    AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM.
    Formula:C32H38F2N2O5S2
    Purity:98.1%
    Color and Shape:Solid
    Molecular weight:632.781