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CCR

CCR

C-C chemokine receptors (CCRs) are a group of GPCRs that respond to chemokines, which are signaling molecules that guide the migration of immune cells to sites of inflammation or infection. CCRs play crucial roles in immune responses, inflammation, and the development of various diseases, including autoimmune disorders and cancer. Modulation of CCR activity is being explored as a therapeutic strategy for conditions such as rheumatoid arthritis, multiple sclerosis, and HIV infection. At CymitQuimica, we provide a range of high-quality CCR modulators to support your research in immunology, inflammation, and therapeutic development.

Found 136 products of "CCR"

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  • CCR7 Ligand 1
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    CCR7 Ligand 1

    CAS:
    <p>CCR7-Cmp2105 is a thiadiazole-dioxide allosteric antagonist for CCR7 with a Kd of 3 nM and IC50 of 7.3 μM against arrestin binding.</p>
    Formula:C22H29N5O5S
    Color and Shape:Solid
    Molecular weight:475.56

    Ref: TM-T10716

  • PF-07054894
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    PF-07054894

    CAS:
    <p>PF-07054894: potent CCR6 antagonist, targets GPCR, for inflammatory bowel disease research.</p>
    Formula:C24H30N6O4
    Color and Shape:Solid
    Molecular weight:466.53

    Ref: TM-T73005

  • Aplaviroc hydrochloride
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    Aplaviroc hydrochloride

    CAS:
    <p>Aplaviroc, a potent CCR5 inhibitor, binds selectively, blocking HIV entry and specific monoclonal antibody attachment in vitro.</p>
    Formula:C33H44ClN3O6
    Color and Shape:Solid
    Molecular weight:614.17

    Ref: TM-T26642

  • INCB-9471 dihydrochloride
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    INCB-9471 dihydrochloride

    CAS:
    <p>INCB-9471 HCl: a potent CCR5 antagonist, blocks monocyte migration &amp; HIV-1.</p>
    Formula:C30H42Cl2F3N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:632.59

    Ref: TM-T27604

  • CymitQuimica logo
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    CCR1 antagonist 11 hydrochloride

    <p>Oral CCR1 antagonist A1B1 targets h/m/rCCR1 (IC50: 0.03/0.58/0.32 μM), potential for treating inflammatory diseases.</p>
    Color and Shape:Solid

    Ref: TM-T64242

  • TAK-661
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    TAK-661

    CAS:
    <p>TAK-661 is an inhibitor of eosinophil chemotaxis (eosinophil chemotaxis) that significantly alleviates late-phase bronchoconstriction while inhibiting the proliferation of eosinophils in bronchoalveolar lavage (BAL) and their infiltration into the airway walls.</p>
    Formula:C13H21N5O3S
    Color and Shape:Solid
    Molecular weight:327.40

    Ref: TM-T201069

  • CP-481715
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    CP-481715

    CAS:
    <p>CP 481715 is an effective selective CCR1 antagonist with potential therapeutic significance for inflammatory diseases.</p>
    Formula:C26H31FN4O4
    Color and Shape:Solid
    Molecular weight:482.55

    Ref: TM-T31061

  • Ophiobolin C
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    Ophiobolin C

    CAS:
    <p>inhibitor of human CCR5 binding to HIV-1 gp120</p>
    Formula:C25H38O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:386.57

    Ref: TM-T23108

  • BAY-3153
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    BAY-3153

    CAS:
    <p>BAY-3153 is a selective CCR1 ( C-C motif chemokine receptor 1 ) antagonist (human IC 50 =3 nM ; rat IC 50 =11 nM ; mice IC 50 =81 nM) .</p>
    Formula:C25H29Cl2N3O4
    Color and Shape:Solid
    Molecular weight:506.42

    Ref: TM-T73371

  • BI 639667
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    BI 639667

    CAS:
    <p>BI 639667, an azaindazole-class compound, potently inhibits CCR1 (IC50=1.8 nM in calcium flux assays).</p>
    Formula:C22H18FN5O3S
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:451.47

    Ref: TM-T14899

  • CCR1 antagonist 13
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    CCR1 antagonist 13

    CAS:
    <p>CCR1 antagonist13 is a selective small molecule antagonist of CCR1.</p>
    Formula:C25H27ClFN3O4
    Color and Shape:Solid
    Molecular weight:487.95

    Ref: TM-T207224

  • BMS-741672
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    BMS-741672

    CAS:
    <p>BMS-741672 is a potent, selective CCR2 antagonist for the treatment of neuropathic pain.</p>
    Formula:C25H33F3N6O2
    Color and Shape:Solid
    Molecular weight:506.56

    Ref: TM-T71640

  • Nifeviroc
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    Nifeviroc

    CAS:
    <p>Nifeviroc (TD-0232) is an orally active CCR5 antagonist, useful in HIV-1 infection research.</p>
    Formula:C33H42N4O6
    Purity:98.14%
    Color and Shape:Solid
    Molecular weight:590.71

    Ref: TM-T28171

  • MK-0812
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    MK-0812

    CAS:
    <p>MK-0812 is a dual antagonist of the CCR2 and CCR5 receptors that can alleviate adipose inflammation in ob/ob mice.</p>
    Formula:C24H34F3N3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:469.54

    Ref: TM-TQ0182

  • AZD-5672
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    AZD-5672

    CAS:
    <p>AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM.</p>
    Formula:C32H38F2N2O5S2
    Purity:98.1%
    Color and Shape:Solid
    Molecular weight:632.78

    Ref: TM-T30260

  • BX471 hydrochloride
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    BX471 hydrochloride

    CAS:
    <p>BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with a Ki of 1 nM for human CCR1, exhibiting 250-fold selectivity over CCR2, CCR5, and CXCR4.</p>
    Formula:C21H25Cl2FN4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:471.35

    Ref: TM-T14845

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    Discontinued
    Discontinued product