CXCR
CXCRs are a subset of GPCRs that bind to chemokines, small signaling proteins that guide the movement of immune cells towards sites of inflammation, infection, or injury. CXCRs play crucial roles in immune responses, cancer metastasis, and inflammatory diseases. Modulators of CXCRs are being investigated for their potential in treating autoimmune diseases, cancer, and chronic inflammatory conditions. At CymitQuimica, we offer a range of high-quality CXCR modulators to support your research in immunology, oncology, and inflammation.
Found 159 products for "CXCR".
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Delmetacin
CAS:Delmetacin: a non-steroidal anti-inflammatory drug with analgesic properties, inhibits CXCR1.Formula:C18H15NO3Purity:99.91%Color and Shape:SolidMolecular weight:293.32Quetmolimab
CAS:Quetmolimab is a humanized monoclonal antibody targeting chemokine ligand 1 (CX3CL1) that can be used to study rheumatoid arthritis.Purity:SDS-PAGE:95% SEC-HPLC:97.59%Color and Shape:Transparent LiquidMolecular weight:150 kDaLY2510924 acetate(1088715-84-7 free base)
Ly2510924 acetate is an potent and selective CXCR4 antagonist. It prevents the binding of SDF-1 to CXCR4 with an IC50 of 0.079 nM.Formula:C64H91N13O13Purity:97.32%Color and Shape:SolidMolecular weight:1250.49Ref: TM-T15805L
1mg150.00€5mg290.00€10mg434.00€1mL*10mM (DMSO)692.00€25mg710.00€50mg973.00€100mg1,341.00€Reparixin L-lysine salt
CAS:Reparixin L-lysine salt (Repertaxin L-lysine salt) is an allosteric chemokine receptor 1/2 (CXCR1/2) activation inhibitor.Formula:C20H35N3O5SPurity:99%Color and Shape:White SolidMolecular weight:429.57VUF11207 fumarate
CAS:VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).Formula:C31H39FN2O8Purity:97.98%Color and Shape:SolidMolecular weight:586.65Ref: TM-T13324
1mg40.00€2mg52.00€5mg84.00€1mL*10mM (DMSO)92.00€10mg130.00€25mg259.00€50mg447.00€100mg645.00€200mg897.00€Eldelumab
CAS:Eldelumab (BMS-936557) is an anti-IP-10 IgG 1 monoclonal antibody.Eldelumab has anti-inflammatory activity and is used to study rheumatoid arthritis.Purity:95%Color and Shape:Transparent LiquidMolecular weight:146.64 kDaAMG 487
CAS:AMG 487: potent CXCR3 antagonist, blocks CXCL10/CXCL11 binding, IC50s: 8.0/8.2 nM.Formula:C32H28F3N5O4Purity:99.82% - 99.89%Color and Shape:SolidMolecular weight:603.59Ref: TM-T10297L
1mg52.00€5mg103.00€1mL*10mM (DMSO)138.00€10mg148.00€25mg235.00€50mg334.00€100mg528.00€200mg752.00€Motixafortide TFA(664334-36-5,Free)
Motixafortide TFA is a CXCR4 antagonist with ~1 nM IC50, promoting AML apoptosis by modulating miR-15a/16-1 and downregulating ERK and BCL-2.Formula:C99H145F4N33O21S2Purity:>99.99%Color and Shape:White SolidMolecular weight:2273.54Peptide R
CAS:Peptide R, a cyclic CXCR4 antagonist, remodels tumor stroma, aiding cancer research.Formula:C39H59N13O8S2Color and Shape:SolidMolecular weight:902.1ITIC
CAS:"ITIC, a non-fullerene acceptor with high Tg of 180°C, shows excellent thermal stability and a low glass-crystal transition, plus unique crystallization."Formula:C94H82N4O2S4Purity:98%Color and Shape:SolidMolecular weight:1427.96CXCR4 antagonist 2
CAS:CXCR4 antagonist 2 is a CXCR4 antagonist with an IC 50 value of 47 nM.Formula:C25H36N6Color and Shape:SolidMolecular weight:420.605CTCE-9908
CAS:CXCR4 blocker; triggers cell division failure in ovarian cancer, boosts taxol and docetaxel treatment effects, proven in mice.Formula:C86H147N27O23Purity:98%Color and Shape:SolidMolecular weight:1927.27ACKR3 agonist 1
ACKR3 agonist 1 (compound 27), exhibiting selective agonistic properties for ACKR3 (EC 50 =69 nM, E max =82%), demonstrates the capability to inhibit platelet aggregation and shows potential in mitigating platelet-mediated thrombosis. This compound is characterized by its metabolic stability and non-cytotoxic nature.Formula:C25H30N2OSColor and Shape:SolidMolecular weight:406.58PF-06835375
CAS:PF-06835375 is a humanized IgG1 antibody that selectively targets CXCR5 expressed on B cells, Tfh cells, and circulating Tfh-like cells (cTfh). It is applicable for research into systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA).Color and Shape:LiquidCXCR4 antagonist 1
CAS:CXCR4 antagonist 1 is a potent inhibitor of the CXCR4 receptor, with notable anti-HIV activity.Formula:C27H43N7Color and Shape:SolidMolecular weight:465.69TC14012
CAS:CXCR4 antagonist and ACKR3 (CXCR7) agonist (EC50 = 350 nM for CXCR7).Formula:C90H140N34O19S2Purity:98%Color and Shape:SolidMolecular weight:2066.43Vimnerixin
CAS:Vimnerixin (AZD4721) is an orally administered CXCR2 antagonist for inflammation studies.Formula:C19H25FN4O5S2Purity:99.52%Color and Shape:White SolidMolecular weight:472.55PDE4D inhibitor 1
PDE4-IN-1 is a PDE4 inhibitor characterized by high potency (IC50: 8.6 nM) and superior selectivity over other PDE subtypes. This compound inhibits the release of inflammatory cytokines and chemokines. Additionally, PDE4-IN-1 significantly restores the damaged cAMP-CREB signaling pathway, inhibits proliferation, and promotes differentiation to reverse psoriasis formation.Color and Shape:Odour SolidITIC-4F
CAS:ITIC-4F: a postfullerene IDTT electron acceptor for high-efficiency PSCs, relevant in binary, ternary, and tandem setups.Formula:C94H78F4N4O2S4Purity:98%Color and Shape:SolidMolecular weight:1499.92Bam 12P
CAS:Bam 12P is a Pro-Met-enkephalin precursor that is isolated from the bovine adrenal medulla.Formula:C62H97N21O16SPurity:98%Color and Shape:SolidMolecular weight:1424.64
