CXCR
CXCRs are a subset of GPCRs that bind to chemokines, small signaling proteins that guide the movement of immune cells towards sites of inflammation, infection, or injury. CXCRs play crucial roles in immune responses, cancer metastasis, and inflammatory diseases. Modulators of CXCRs are being investigated for their potential in treating autoimmune diseases, cancer, and chronic inflammatory conditions. At CymitQuimica, we offer a range of high-quality CXCR modulators to support your research in immunology, oncology, and inflammation.
Found 188 products for "CXCR".
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Delmetacin
CAS:Delmetacin: a non-steroidal anti-inflammatory drug with analgesic properties, inhibits CXCR1.Formula:C18H15NO3Purity:99.91%Color and Shape:SolidMolecular weight:293.3166VUF11207 fumarate
CAS:VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).Formula:C31H39FN2O8Purity:97.98%Color and Shape:SolidMolecular weight:586.65Ref: TM-T13324
1mg40.00€2mg52.00€5mg84.00€1mL*10mM (DMSO)92.00€10mg130.00€25mg259.00€50mg447.00€100mg645.00€200mg897.00€LY2510924 acetate
Ly2510924 acetate is an potent and selective CXCR4 antagonist. It prevents the binding of SDF-1 to CXCR4 with an IC50 of 0.079 nM.Formula:C64H91N13O13Purity:97.32%Color and Shape:SolidMolecular weight:1250.49Ref: TM-T15805L
1mg150.00€5mg290.00€10mg434.00€1mL*10mM (DMSO)692.00€25mg710.00€50mg973.00€100mg1,341.00€Reparixin L-lysine salt
CAS:Reparixin L-lysine salt (Repertaxin L-lysine salt) is an allosteric chemokine receptor 1/2 (CXCR1/2) activation inhibitor.Formula:C20H35N3O5SPurity:99%Color and Shape:White SolidMolecular weight:429.574Quetmolimab
CAS:Quetmolimab is a humanized monoclonal antibody targeting chemokine ligand 1 (CX3CL1) that can be used to study rheumatoid arthritis.Purity:SDS-PAGE:95% SEC-HPLC:97.59%Color and Shape:Transparent LiquidMolecular weight:~150 kDaEldelumab
CAS:Eldelumab (BMS-936557) is an anti-IP-10 IgG 1 monoclonal antibody.Eldelumab has anti-inflammatory activity and is used to study rheumatoid arthritis.Purity:95%Color and Shape:Transparent LiquidMolecular weight:146.64 kDa (Predicted)AMG 487
CAS:AMG 487: potent CXCR3 antagonist, blocks CXCL10/CXCL11 binding, IC50s: 8.0/8.2 nM.Formula:C32H28F3N5O4Purity:99.82% - 99.89%Color and Shape:SolidMolecular weight:603.59Ref: TM-T10297L
1mg52.00€5mg103.00€1mL*10mM (DMSO)138.00€10mg148.00€25mg235.00€50mg334.00€100mg528.00€200mg752.00€Motixafortide TFA
Motixafortide TFA is a CXCR4 antagonist with ~1 nM IC50, promoting AML apoptosis by modulating miR-15a/16-1 and downregulating ERK and BCL-2.Formula:C99H145F4N33O21S2Purity:>99.99%Color and Shape:White SolidMolecular weight:2273.54Bam 12P
CAS:Bam 12P is a Pro-Met-enkephalin precursor that is isolated from the bovine adrenal medulla.Formula:C62H97N21O16SPurity:98%Color and Shape:SolidMolecular weight:1424.64CTCE-9908
CAS:CXCR4 blocker; triggers cell division failure in ovarian cancer, boosts taxol and docetaxel treatment effects, proven in mice.Formula:C86H147N27O23Purity:98%Color and Shape:SolidMolecular weight:1927.27Polyphemusin II-Derived Peptide
CAS:T140, a Polyphemusin II-derived peptide, inhibits HIV-1 entry and blocks anti-CXCR4 antibody (12G5) binding.Formula:C90H141N33O18S2Color and Shape:SolidMolecular weight:2037.42Vimnerixin
CAS:Vimnerixin (AZD4721) is an orally administered CXCR2 antagonist for inflammation studies.Formula:C19H25FN4O5S2Purity:99.52%Color and Shape:White SolidMolecular weight:472.554Peptide R
CAS:Peptide R, a cyclic CXCR4 antagonist, remodels tumor stroma, aiding cancer research.Formula:C39H59N13O8S2Color and Shape:SolidMolecular weight:902.1TC14012
CAS:CXCR4 antagonist and ACKR3 (CXCR7) agonist (EC50 = 350 nM for CXCR7).Formula:C90H140N34O19S2Purity:98%Color and Shape:SolidMolecular weight:2066.43ITIC
CAS:"ITIC, a non-fullerene acceptor with high Tg of 180°C, shows excellent thermal stability and a low glass-crystal transition, plus unique crystallization."Formula:C94H82N4O2S4Purity:98%Color and Shape:SolidMolecular weight:1427.942LN6023 hydrochloride
LN6023 (hydrochloride) (Compound 27) acts as a CXCR7 agonist. It can stimulate the recruitment of β-arrestin in HEK293T cells expressing human CXCR7, with an EC50 of 3.5 µM. Additionally, LN6023 (hydrochloride) reduces surface levels of P-selectin in isolated and washed human platelets and is applicable in studies of platelet-mediated thrombosis.KRH-3955 hydrochloride
CAS:KRH-3955 hydrochloride is an orally available CXCR4 blocker with IC50 of 0.61 nM and EC50 of 0.3-1.0 nM against X4 HIV-1.Formula:C28H48Cl3N7Color and Shape:SolidMolecular weight:589.09CXCR4 antagonist 2
CAS:CXCR4 antagonist 2 is a CXCR4 antagonist with an IC 50 value of 47 nM.Formula:C25H36N6Color and Shape:SolidMolecular weight:420.605ITIC-4F
CAS:ITIC-4F: a postfullerene IDTT electron acceptor for high-efficiency PSCs, relevant in binary, ternary, and tandem setups.Formula:C94H78F4N4O2S4Purity:98%Color and Shape:SolidMolecular weight:1499.904CXCR7 modulator 1
CAS:CXCR7 modulator 1 is an effective and orally bioavailable peptoid hybrid CXCR7 modulator with Ki of 9 nM.Formula:C48H57F2N7O7SPurity:98%Color and Shape:SolidMolecular weight:914.071
