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TLR

TLR

Toll-like receptors (TLRs) are a class of proteins that play a critical role in the innate immune system by recognizing pathogen-associated molecular patterns (PAMPs) and initiating immune responses. TLRs are involved in detecting a wide range of pathogens, including bacteria, viruses, and fungi, and are essential for the activation of inflammatory signaling pathways. Dysregulation of TLR signaling is associated with chronic inflammatory diseases, autoimmune disorders, and cancer. At CymitQuimica, we offer a variety of high-quality TLR modulators to support your research in innate immunity, inflammation, and infectious disease.

Found 66 products of "TLR"

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  • Neoseptin-3
    Targetmol
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    Neoseptin-3

    CAS:
    <p>Neoseptin-3 is a novel small molecule agonist of mouse mTLR4/MD2 with EC50=18.5 μM that does not activate human TLR4/MD2.</p>
    Formula:C29H34N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:474.59

    Ref: TM-T16284

  • Toll-like receptor modulator
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    Toll-like receptor modulator

    CAS:
    <p>Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function.</p>
    Formula:C15H13F5N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:348.27

    Ref: TM-T13182

  • Pam3CSK4
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    Pam3CSK4

    CAS:
    <p>Pam3CSK4 is a synthetic triacylated lipopeptide (LP) that mimics the acylated amino terminus of bacterial LPs.</p>
    Formula:C81H156N10O13S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1510.23

    Ref: TM-TP1068

  • Bropirimine
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    Bropirimine

    CAS:
    <p>Bropirimine (U-54461) (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.</p>
    Formula:C10H8BrN3O
    Purity:99.01%
    Color and Shape:Solid
    Molecular weight:266.09

    Ref: TM-T5521

  • TLR7 agonist 2
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    TLR7 agonist 2

    CAS:
    <p>TLR7 agonist 2 (TLR7-IN-1) is a specific and effective Toll-like Receptor 7 (TLR7) agonist (LEC=0.4 μM).</p>
    Formula:C17H16N6O2
    Purity:99.33%
    Color and Shape:Solid
    Molecular weight:336.35

    Ref: TM-T4258

  • TLR7/8 agonist 1
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    TLR7/8 agonist 1

    CAS:
    <p>TLR7/8 agonist 1 is a toll-like receptor TLR7/TLR8 agonist with anticancer and antiviral activities and can be used to study immune-related diseases.</p>
    Formula:C22H25N5
    Purity:99.4%
    Color and Shape:Solid
    Molecular weight:359.47

    Ref: TM-T71108

  • Telratolimod
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    Telratolimod

    CAS:
    <p>Telratolimod (MEDI9197) is a toll-like receptors 7/8 agonist. It has an antitumor activity.</p>
    Formula:C36H59N5O2
    Purity:98.61%
    Color and Shape:Solid
    Molecular weight:593.89

    Ref: TM-T17032

  • Enpatoran
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    Enpatoran

    CAS:
    <p>Enpatoran is an inhibitor of TLR7(IC50 = 11.1 nM) and TLR8(IC50 = 24.1 nM).</p>
    Formula:C16H15F3N4
    Purity:97.08% - 99.38%
    Color and Shape:Solid
    Molecular weight:320.31

    Ref: TM-T9570

  • Gardiquimod
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    Gardiquimod

    CAS:
    <p>Gardiquimod, an imidazoquinoline TLR7 agonist, inhibits HIV-1 in macrophages and PBMCs under 10μM.</p>
    Formula:C17H23N5O
    Purity:98.02% - 99.68%
    Color and Shape:Solid
    Molecular weight:313.4

    Ref: TM-T15371

  • CU-CPT-8m
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    CU-CPT-8m

    CAS:
    <p>CU-CPT-8m (TLR8-specific antagonist) is an toll-like receptor 8 (TLR8) antagonist (IC50 : 67 nM)</p>
    Formula:C14H12N4O
    Purity:99.00%
    Color and Shape:Solid
    Molecular weight:252.27

    Ref: TM-T7347

  • SM-324405
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    SM-324405

    CAS:
    <p>SM-324405 is an agonist of TLR7.</p>
    Formula:C19H23N5O4
    Purity:97.83%
    Color and Shape:Solid
    Molecular weight:385.42

    Ref: TM-T7860

  • CU-CPT9b
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    CU-CPT9b

    CAS:
    <p>CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM).</p>
    Formula:C16H13NO2
    Purity:98.1%
    Color and Shape:Solid
    Molecular weight:251.28

    Ref: TM-T7302

  • MD2-IN-1
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    MD2-IN-1

    CAS:
    <p>MD2-IN-1 is a Myeloid differentiation protein 2 (MD2) inhibitor with a KD of 189  μM for the recombinant human MD2 (rhMD2).</p>
    Formula:C20H22O6
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:358.39

    Ref: TM-T4231

  • C29
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    C29

    CAS:
    <p>C29 inhibits TLR2/1 and TLR2/6 in human cells, but only TLR2/1 in mouse macrophages.</p>
    Formula:C16H15NO4
    Purity:96.34% - 97.37%
    Color and Shape:Solid
    Molecular weight:285.29

    Ref: TM-T3502

  • TLR3-IN-1
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    TLR3-IN-1

    CAS:
    <p>TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor. It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the TNF-α and IL-1β.</p>
    Formula:C18H13ClFNO3S
    Purity:98.56%
    Color and Shape:Solid
    Molecular weight:377.82

    Ref: TM-T22698

  • CU-CPT-9a
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    CU-CPT-9a

    CAS:
    <p>CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM), that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells-</p>
    Formula:C17H15NO2
    Purity:99.01%
    Color and Shape:Solid
    Molecular weight:265.31

    Ref: TM-T7317

  • TLR7/8/9-IN-1
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    TLR7/8/9-IN-1

    CAS:
    <p>TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM.</p>
    Formula:C27H37N3O2
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:435.6

    Ref: TM-T39669

  • Pam3CSK4 TFA (112208-00-1 free base)
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    Pam3CSK4 TFA (112208-00-1 free base)

    CAS:
    <p>Pam3CSK4 TFA (Pam3Cys-Ser-(Lys)4 TFA) is a Toll-like receptor 1/2 agonist with EC50 of 0.47 ng/mL for human TLR1/2.Cost-effective and quality-assured.</p>
    Formula:C87H159F9N10O19S
    Purity:96.4% - 99.01%
    Color and Shape:Solid
    Molecular weight:1852.33

    Ref: TM-TP1067

  • TLR4-IN-C34
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    TLR4-IN-C34

    CAS:
    <p>TLR4-IN-C34 is an inhibitor of TLR4, and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis</p>
    Formula:C17H27NO9
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:389.4

    Ref: TM-T8503

  • 1V209
    Targetmol
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    1V209

    CAS:
    <p>1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects.</p>
    Formula:C16H17N5O5
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:359.34

    Ref: TM-T8316