MALT
Mucosa-associated lymphoid tissue (MALT) is an essential component of the immune system that protects mucosal surfaces from pathogens. MALT includes structures such as the tonsils, Peyer's patches, and the appendix, which are involved in the initiation of immune responses to antigens encountered at mucosal surfaces. Research on MALT is critical for understanding the mechanisms of mucosal immunity and the development of vaccines and treatments for mucosal infections. At CymitQuimica, we provide a range of reagents and tools to support your research in mucosal immunology, inflammation, and infectious diseases.
Found 26 products for "MALT".
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MLT-231
MLT-231: potent MALT1 Inhibitor, IC50=9 nM; blocks BCL10 cleavage, IC50=160 nM; exhibits antitumor efficacy in mouse ABC-DLBCL model.Color and Shape:SolidPROTAC MALT1 Degrader-1
CAS:PROTAC MALT1 Degrader-1 (Compound 176) is a MALT1 PROTAC degrader, utilized in lymphoma research.Formula:C42H47ClN12O5Molecular weight:835.35MALT1-IN-14
CAS:MALT1-IN-14 (comp 2) is a potent and selective MALT1 inhibitor with an IC50 value of 0.081 μM, widely utilized in immunology and oncology research to suppress MALT1 protease activity, dissect NF-κB signaling cascades, and evaluate therapeutic approaches targeting lymphoid malignancies and inflammatory diseases driven by dysregulated immune activation.Formula:C26H25ClF5N5O3SColor and Shape:SolidMolecular weight:618.02MLT-985
CAS:MLT-985 is a highly selective allosteric MALT1 inhibitor with an IC50 of 3 nM, and can be used to study MALT1 signaling, cancer, and B-cell malignancies.Formula:C17H15Cl2N9O2Purity:98.15%Color and Shape:SolidMolecular weight:448.27Cladribine
CAS:Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.Formula:C10H12ClN5O3Purity:99.58% - >99.99%Color and Shape:SolidMolecular weight:285.687MALT1 inhibitor MI-2
CAS:MI-2 (MALT1 inhibitor) is an irreversible MALT1 inhibitor.Formula:C19H17Cl3N4O3Purity:98% - 99.87%Color and Shape:SolidMolecular weight:455.72MLT-943
CAS:MLT-943 is a potent, selective and orally active MALT1 protease inhibitor. [1].Formula:C16H14ClF3N6O2Purity:99.72% - 99.82%Color and Shape:White SolidMolecular weight:414.77MLT-748
CAS:MLT-748 is an effective, selective, and allosteric MALT1 inhibitor. It binds MALT1 in the allosteric Trp580 pocket (IC50: 5 nM).Formula:C19H19Cl2N9O3Purity:99.20%Color and Shape:SolidMolecular weight:492.319Z-VRPR-FMK
CAS:Z-VRPR-FMK: irreversible MALT1 inhibitor, halts growth/invasion of diffused B-cell lymphoma by blocking NF-κB activation and MMP expression.Formula:C31H49FN10O6Color and Shape:SolidMolecular weight:676.78(R)-MALT1-IN-3
CAS:(R)-MALT1-IN-3 (121) inhibits MALT1 protease (IC50: 20 nM) and IL6/IL10 in OCI-LY3 (IC50: 60/40 nM).Formula:C21H19F3N8O2Color and Shape:SolidMolecular weight:472.42(R)-MLT-985
CAS:(R)-MLT-985 (compound 11) is a MALT1 protease inhibitor with IC50 of 3 nM, also blocking IL-2 in Jurkat cells and ABC-DLBCL cell growth.Formula:C17H15Cl2N9O2Color and Shape:SolidMolecular weight:448.27MALT1-IN-3
CAS:MALT1-IN-3 is a potent inhibitor of MALT1 protease (IC50: 0.06 μM) with IC50 values of 0.14 and 0.13 μM for human IL6 and IL10, respectively, in OCI-LY3 cells.Formula:C21H19F3N8O2Color and Shape:SolidMolecular weight:472.42MALT1-IN-8
CAS:MALT1-IN-8: potent MALT1 inhibitor, IC50=2 nM; hinders OCI-LY3 cells, IC50=1.16 μM; anticancer, from patent WO2018165385A1.Formula:C20H15Cl2N7OColor and Shape:SolidMolecular weight:440.29MLT-747
CAS:MLT-747 is an effective and allosteric inhibitor of MALT1. It binds MALT1 in the allosteric Trp580 pocket (IC50: 14 nM).Formula:C20H21Cl2N7O3Color and Shape:SolidMolecular weight:478.332(R)-MALT1-IN-7
CAS:(R)-MALT1-IN-7 (compound 142a) is a potent inhibitor of MALT1 protease and has potential for cancer research.Formula:C19H17F3N8O2SColor and Shape:SolidMolecular weight:478.45NVS-MALT1
CAS:NVS-MALT1 is an allosteric inhibitor of MALT1 [1].Formula:C24H27ClF3N5O4SColor and Shape:SolidMolecular weight:574.02MALT1-IN-6
CAS:MALT1-IN-6 is a MALT1 protease inhibitor (Ki: 9 nM) that exhibits anticancer activity.Formula:C18H12Cl2F3N9OColor and Shape:SolidMolecular weight:498.25JNJ-67856633
CAS:JNJ-67856633 is an orally active, first-in-class, potent, selective and allosteric inhibitor of MALT1 protease .Formula:C20H11F6N5O2Purity:99.87%Color and Shape:SolidMolecular weight:467.3241MALT1-IN-9
CAS:MALT1-IN-9: potent MALT1 protease inhibitor, IC50 <500 nM in Raji cells, significant anticancer effects.Formula:C16H12ClF3N6OColor and Shape:SolidMolecular weight:396.75MALT1-IN-7
CAS:MALT1-IN-7 (compound 142b) is a potent inhibitor of MALT1 protease with potential for cancer research.Formula:C19H17F3N8O2SColor and Shape:SolidMolecular weight:478.45
