JAK

JAK (Janus kinase) inhibitors are compounds that target the JAK-STAT signaling pathway, which is involved in cell growth, immune response, and angiogenesis. By inhibiting JAK, these compounds can reduce the signaling that leads to the formation of new blood vessels in tumors, thereby inhibiting tumor growth. JAK inhibitors are important in the treatment of cancers and inflammatory diseases. At CymitQuimica, we offer a diverse range of high-quality JAK inhibitors to support your research in oncology, immunology, and angiogenesis.

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Brand	Product data	Purity	Price range	Estimated delivery
	(R)-9b REF: TM-T201776CAS: 1655527-68-6	- - -	To inquire	Mon 21 Jul 25
	AJI-100 REF: TM-T200052CAS: 844435-10-5	- - -	To inquire	Mon 21 Jul 25
	AJI-214 REF: TM-T200387CAS: 1395886-20-0	- - -	To inquire	Mon 21 Jul 25
	Tyk2-IN-20 REF: TM-T201155CAS: 3058568-08-1	- - -	To inquire	Mon 21 Jul 25
	JBJ-02-112-05 REF: TM-T11713CAS: 2748162-29-8	98%	907.00 €~2,375.00 €	Mon 21 Jul 25
	GDC-9918 REF: TM-T201178CAS: 2570375-06-1	- - -	To inquire	Mon 21 Jul 25
	AZ-3 REF: TM-T10424CAS: 2228908-91-4	98%	To inquire	Mon 21 Jul 25
	JAK3-IN-7 REF: TM-T10009CAS: 1263774-57-7	98.81%	665.00 €~3,515.00 €	Mon 21 Jul 25
	JDTic dihydrochloride REF: TM-T11721LCAS: 785835-79-2	98%	62.00 €~1,225.00 €	Mon 21 Jul 25
	MM-589 TFA REF: TM-T12091LCAS: 2097887-21-1	98%	1,841.00 €~4,940.00 €	Mon 21 Jul 25
	JAK2-IN-11 REF: TM-T201601CAS: 3057053-17-2	- - -	To inquire	Mon 21 Jul 25
	JAK3 covalent inhibitor-1 REF: TM-T11709CAS: 2300106-50-5	98%	1,655.00 €~5,853.00 €	Mon 21 Jul 25
	JAK1-IN-16 REF: TM-T201648	- - -	To inquire	Mon 21 Jul 25
	ITK inhibitor 2 REF: TM-T11690CAS: 1309784-09-5	- - -	53.00 €~1,121.00 €	Mon 21 Jul 25
	JAK2-IN-7 REF: TM-T35900CAS: 2593402-36-7	98.71%	145.00 €~2,357.00 €	Mon 04 Aug 25
	4-(3'-HYDROXYPHENYL)AMINO-6,7-DIMETHOXYQUINAZOLINE, HCL REF: IN-DA00AB8ZCAS: 153437-55-9	97.0%	- - -	Discontinued product

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(R)-9b

CAS:1655527-68-6

(R)-9b is an effective inhibitor of the ACK1 tyrosine kinase (IC50=56 nM) and exhibits anticancer …

Formula:

C₂₀H₂₇ClN₆O

Color and Shape:

Liquid

Molecular weight:

402.92

Ref: TM-T201776

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 21 Jul 2025

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AJI-100

CAS:844435-10-5

AJI-100 serves as a dual-target inhibitor, effectively blocking Aurora kinase A and JAK2, with respective …

Formula:

C₁₇H₁₄FN₅O

Color and Shape:

Liquid

Molecular weight:

323.32

Ref: TM-T200052

25mg		1,444.00 €
50mg		1,882.00 €
100mg		2,375.00 €

Estimated delivery in United States, on Monday 21 Jul 2025

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AJI-214

CAS:1395886-20-0

AJI-214 functions as a dual-target inhibitor that specifically blocks Aurora kinase A and JAK2. By …

Formula:

C₁₇H₁₃ClFN₅O

Color and Shape:

Liquid

Molecular weight:

357.77

Ref: TM-T200387

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 21 Jul 2025

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Tyk2-IN-20

CAS:3058568-08-1

Tyk2-IN-20 (Example 289) is an effective inhibitor of Tyk2 with an IC50 value below 5 …

Formula:

C₂₄H₂₅N₇O₂

Color and Shape:

Liquid

Molecular weight:

443.50

Ref: TM-T201155

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 21 Jul 2025

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JBJ-02-112-05

CAS:2748162-29-8

JBJ-02-112-05 is a potent, mutant-selective, allosteric and orally active inhibitor of EGFR with an IC …

Formula:

C₂₇H₂₀N₄O₂S

Purity:

98%

Color and Shape:

Solid

Molecular weight:

464.54

Ref: TM-T11713

25mg		1,444.00 €
50mg		1,882.00 €
100mg		2,375.00 €

Estimated delivery in United States, on Monday 21 Jul 2025

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GDC-9918

CAS:2570375-06-1

GDC-9918 (compound GDC-9918) is an inhibitor of Janus kinases.

Formula:

C₂₀H₁₈F₂N₆O₅S

Color and Shape:

Liquid

Molecular weight:

492.46

Ref: TM-T201178

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 21 Jul 2025

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AZ-3

CAS:2228908-91-4

AZ-3 is a potent and selective JAK1 inhibitor (IC50: 34 nM).

Formula:

C₂₀H₂₈FN₇

Purity:

98%

Color and Shape:

Solid

Molecular weight:

385.48

Ref: TM-T10424

25mg		To inquire
50mg		To inquire
100mg		To inquire

Estimated delivery in United States, on Monday 21 Jul 2025

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JAK3-IN-7

CAS:1263774-57-7

JAK3-IN-7 is a potent and selective JAK3 inhibitor (IC50<0.01 μM) for the treatment of …

Formula:

C₁₇H₂₀N₆O

Purity:

98.81%

Color and Shape:

Solid

Molecular weight:

324.38

Ref: TM-T10009

25mg		2,015.00 €
50mg		2,642.00 €
100mg		3,515.00 €

Estimated delivery in United States, on Monday 21 Jul 2025

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JDTic dihydrochloride

JDTic dihydrochloride

CAS:785835-79-2

JDTic is a powerful antagonist of kappa-opioid receptors (KOR), effectively inhibiting the antinociceptive effects induced …

Formula:

C₂₈H₄₁Cl₂N₃O₃

Purity:

98%

Color and Shape:

Solid

Molecular weight:

538.55

Ref: TM-T11721L

2mg		104.00 €
25mg		635.00 €
50mg		825.00 €
100mg		1,225.00 €

Estimated delivery in United States, on Monday 21 Jul 2025

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MM-589 TFA

CAS:2097887-21-1

MM-589 TFA is a potent WD repeat domain 5 (WDR5)inhibitor and mixed lineage leukemia (MLL) …

Formula:

C₃₀H₄₅F₃N₈O₇

Purity:

98%

Color and Shape:

Solid

Molecular weight:

686.72

Ref: TM-T12091L

25mg		2,727.00 €
50mg		3,591.00 €
100mg		4,940.00 €

Estimated delivery in United States, on Monday 21 Jul 2025

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JAK2-IN-11

CAS:3057053-17-2

JAK2-IN-11 (Example 6) is a JAK2 kinase inhibitor with potent antitumor activity, exhibiting an IC50 …

Formula:

C₃₁H₃₁F₃N₈O₄

Color and Shape:

Liquid

Molecular weight:

639.64

Ref: TM-T201601

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 21 Jul 2025

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JAK3 covalent inhibitor-1

JAK3 covalent inhibitor-1

CAS:2300106-50-5

JAK3 Covalent Inhibitor-1 is a compound characterized by its potent and selective inhibition of Janus …

Formula:

C₂₂H₁₇FN₆O₂S

Purity:

98%

Color and Shape:

Solid

Molecular weight:

448.47

Ref: TM-T11709

25mg		3,515.00 €
50mg		4,694.00 €
100mg		5,853.00 €

Estimated delivery in United States, on Monday 21 Jul 2025

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JAK1-IN-16

JAK1-IN-16 (compound 4l) acts as an inhibitor of JAK1/STAT3 and effectively downregulates the expression of …

Formula:

C₂₀H₁₅ClF₃N₃OS

Color and Shape:

Liquid

Molecular weight:

437.87

Ref: TM-T201648

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 21 Jul 2025

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ITK inhibitor 2

ITK inhibitor 2

CAS:1309784-09-5

ITK inhibitor 2 is a interleukin-2-inducible T-cell kinase (ITK) inhibitor , with an IC50 of …

Formula:

C₂₅H₃₃N₅O₂

Color and Shape:

Solid

Molecular weight:

435.56

Ref: TM-T11690

50mg		748.00 €
100mg		1,121.00 €

Estimated delivery in United States, on Monday 21 Jul 2025

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JAK2-IN-7

CAS:2593402-36-7

JAK2-IN-7 selectively inhibits JAK2 (IC50: 3 nM), shows 14-fold selectivity over JAK1/3, FLT3, induces G0/G1 …

Formula:

C₂₆H₃₃N₇O

Purity:

98.71%

Color and Shape:

Solid

Molecular weight:

459.59

Ref: TM-T35900

1mg		145.00 €
5mg		354.00 €
10mg		630.00 €
25mg		1,301.00 €
50mg		1,738.00 €
100mg		2,357.00 €
1mL*10mM (DMSO)		358.00 €

Estimated delivery in United States, on Monday 4 Aug 2025

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4-(3'-HYDROXYPHENYL)AMINO-6,7-DIMETHOXYQUINAZOLINE, HCL

4-(3'-HYDROXYPHENYL)AMINO-6,7-DIMETHOXYQUINAZOLINE, HCL

CAS:153437-55-9

Formula:

C₁₆H₁₆ClN₃O₃

Purity:

97.0%

Molecular weight:

333.7695

Ref: IN-DA00AB8Z

5mg		Discontinued	Request information
10mg		Discontinued	Request information
25mg		Discontinued	Request information
50mg		Discontinued	Request information
100mg		Discontinued	Request information

Discontinued product

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