JAK
JAK (Janus kinase) inhibitors are compounds that target the JAK-STAT signaling pathway, which is involved in cell growth, immune response, and angiogenesis. By inhibiting JAK, these compounds can reduce the signaling that leads to the formation of new blood vessels in tumors, thereby inhibiting tumor growth. JAK inhibitors are important in the treatment of cancers and inflammatory diseases. At CymitQuimica, we offer a diverse range of high-quality JAK inhibitors to support your research in oncology, immunology, and angiogenesis.
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STAT3-IN-18
CAS:2668267-41-0
STAT3-IN-18 (compound SPP), a platinum (IV) complex featuring an axial ligand from sandalwood, suppresses the …
Formula:
C18H24Cl2N2O6Pt
Purity:
98%
Color and Shape:
Solid
Molecular weight:
630.38
Ref: TM-T79609
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 11 Jul 2025
Brepocitinib
CAS:1883299-62-4
Brepocitinib (PF-06700841) is a potent dual JAK1/TYK2 inhibitor (IC50s: 17 nM/23 nM). Brepocitinib also inhibits …
Formula:
C18H21F2N7O
Purity:
99.8%
Color and Shape:
Solid
Molecular weight:
389.4
Ref: TM-TQ0010
| 1mg | 55.00 € | ||
| 5mg | 106.00 € | ||
| 10mg | 177.00 € | ||
| 25mg | 359.00 € | ||
| 50mg | 540.00 € | ||
| 100mg | 882.00 € | ||
| 200mg | To inquire | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 117.00 € |
Estimated delivery in United States, on Friday 11 Jul 2025
JAK-IN-34
CAS:2068766-90-3
JAK-IN-34 (compound 11n) is a potent inhibitor of Janus kinases (JAKs), demonstrating IC50 values of …
Formula:
C27H26N6O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
450.53
Ref: TM-T82017
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 11 Jul 2025
TCS 21311
CAS:1260181-14-3
TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective …
Formula:
C27H25F3N4O4
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
526.51
Ref: TM-T17019
| 1mg | 98.00 € |
Estimated delivery in United States, on Friday 11 Jul 2025
Lepzacitinib
CAS:2321488-47-3
Lepzacitinib is a selective, inflammatory, small molecule JAK1/3(Janus kinase) inhibitor primarily used for the treatment …
Formula:
C18H21N5O3
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
355.39
Ref: TM-T78207
| 1mg | 52.00 € | ||
| 5mg | 116.00 € | ||
| 10mg | 178.00 € | ||
| 25mg | 359.00 € | ||
| 50mg | 533.00 € | ||
| 100mg | 750.00 € | ||
| 200mg | 1,064.00 € | ||
| 1mL*10mM (DMSO) | 127.00 € |
Estimated delivery in United States, on Friday 11 Jul 2025
JAK-IN-3
CAS:1400876-94-9
JAK-IN-3 is a potent JAK inhibitor that inhibits JAK3, JAK1, TYK2, and JAK2, and can …
Formula:
C18H20N4O3
Purity:
98.04% - 98.19%
Color and Shape:
Solid
Molecular weight:
340.38
Ref: TM-T11704
| 2mg | 188.00 € | ||
| 5mg | 321.00 € | ||
| 10mg | 518.00 € | ||
| 25mg | 1,035.00 € | ||
| 50mg | 1,644.00 € | ||
| 100mg | 2,680.00 € | ||
| 1mL*10mM (DMSO) | 354.00 € |
Estimated delivery in United States, on Friday 11 Jul 2025
JAK-IN-5
CAS:2096999-92-5
JAK-IN-5 is a JAK inhibitor.
Formula:
C27H31FN6O
Purity:
97.78% - 98.78%
Color and Shape:
Solid
Molecular weight:
474.57
Ref: TM-T11710
| 1mg | 187.00 € | ||
| 5mg | 391.00 € | ||
| 10mg | 582.00 € | ||
| 25mg | 929.00 € | ||
| 50mg | 1,254.00 € | ||
| 100mg | 1,691.00 € | ||
| 500mg | 3,382.00 € | ||
| 1mL*10mM (DMSO) | 567.00 € |
Estimated delivery in United States, on Friday 11 Jul 2025
Ginsenoside Rk1
CAS:494753-69-4
Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.
Formula:
C42H70O12
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
767
Ref: TM-T4S1499
| 5mg | 93.00 € |
Estimated delivery in United States, on Friday 11 Jul 2025
JAK-IN-26
CAS:2417134-93-9
JAK-IN-26 (compound 2) is an orally active inhibitor of the Janus kinase (JAK) enzyme with …
Formula:
C22H24N6O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
420.46
Ref: TM-T78189
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 11 Jul 2025
JAK1-IN-10
CAS:2416858-88-1
JAK1-IN-10 (compound 9), a cyano-substituted cyclic hydrazine derivative, functions as a potent and selective inhibitor …
Formula:
C15H17N7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
295.34
Ref: TM-T79078
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 11 Jul 2025
JAK-IN-31
CAS:2597016-88-9
JAK-IN-31 (Example 75), a JAK inhibitor, demonstrates IC50 values of ≤0.01 µM for JAK1, ≤0.01 …
Formula:
C21H19N7O2S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
465.55
Ref: TM-T79882
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 11 Jul 2025
QL-1200186
CAS:2848664-42-4
QL-1200186 is an orally active, selective TYK2 inhibitor that, upon dose-dependent oral administration, suppresses interferon-γ …
Formula:
C26H27N7O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
485.54
Ref: TM-T81331
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 11 Jul 2025
JAK kinase-IN-1
CAS:2698389-43-2
JAK kinase-IN-1 (Example 1) functions as a potent inhibitor targeting the JAK family, which includes …
Formula:
C17H19F2N7OS
Purity:
98%
Color and Shape:
Solid
Molecular weight:
407.44
Ref: TM-T79807
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 11 Jul 2025
JAK-IN-25
CAS:2127110-22-7
JAK-IN-25 (compound 19), a potent JAK inhibitor, exhibits IC50 values of 6 nM for TYK2, …
Formula:
C19H17N5O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
379.37
Ref: TM-T78175
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 11 Jul 2025
ABBV-712
CAS:2368945-27-9
ABBV-712 is a selective Tyrosine Kinase 2 (TYK2) inhibitor, demonstrating an IC50 value of 0.195 …
Formula:
C24H28N4O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
452.5
Ref: TM-T83218
| 5mg | 1,415.00 € | ||
| 10mg | 1,908.00 € | ||
| 25mg | 2,547.00 € | ||
| 50mg | 3,212.00 € |
Estimated delivery in United States, on Friday 11 Jul 2025
YLIU-4-105-1
CAS:2417685-83-5
YLIU-4-105-1 is a type II JAK2 inhibitor. Demonstrating in vivo pharmacological activity, YLIU-4-105-1 reduces splenic …
Formula:
C32H34F3N7O2
Color and Shape:
Solid
Molecular weight:
605.65
Ref: TM-T201176
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 8 Aug 2025
MM-589
CAS:2097887-20-0
MM-589 is a potent WD repeat domain 5 (WDR5) inhibitor and mixed lineage leukemia (MLL) …
Formula:
C28H44N8O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
572.70
Ref: TM-T12091
| 25mg | 2,727.00 € | ||
| 50mg | 3,591.00 € | ||
| 100mg | 4,940.00 € |
Estimated delivery in United States, on Friday 8 Aug 2025
Londamocitinib
CAS:2241039-81-4
Londamocitinib (JAK1-IN-7) is a selective and potent JAK1 inhibitor with anti-inflammatory activity.
Formula:
C28H31F2N7O4S
Purity:
99.47%
Color and Shape:
Solid
Molecular weight:
599.65
Ref: TM-T11706
| 1mg | 180.00 € | ||
| 5mg | 439.00 € | ||
| 10mg | 597.00 € | ||
| 25mg | 905.00 € | ||
| 50mg | 1,169.00 € | ||
| 100mg | 1,568.00 € | ||
| 1mL*10mM (DMSO) | 567.00 € |
Estimated delivery in United States, on Friday 8 Aug 2025
CP-352664
CAS:1097883-05-0
CP-352664 is a JAK inhibitor with potency against JAK3, exhibiting an EC50 value of 210 …
Formula:
C18H18N4
Color and Shape:
Solid
Molecular weight:
290.36
Ref: TM-T200202
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Friday 8 Aug 2025
Cenacitinib
CAS:2641636-52-2
Cenacitinib is an effective inhibitor of Janus kinase (Janus kinase) and possesses anti-inflammatory activity.
Formula:
C19H19F2N7O3
Color and Shape:
Solid
Molecular weight:
431.40
Ref: TM-T201149
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 8 Aug 2025
