MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
Found 892 products of "MAPK"
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I-49 free base
I-49 free base (Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-) is a novelFormula:C23H26ClF3N4O2Purity:99.64% - 99.88%Color and Shape:SolidMolecular weight:482.92CAY10404
CAS:CAY10404: potent COX-1/2 inhibitor; blocks PKB/Akt, MAPK pathways; triggers NSC-LC apoptosis; analgesic, anti-inflammatory, anti-cancer.Formula:C17H12F3NO3SPurity:99.02%Color and Shape:SolidMolecular weight:367.34TAO Kinase inhibitor 1
CAS:TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death.Formula:C25H24N2O2Purity:99.74%Color and Shape:SolidMolecular weight:384.47Ref: TM-T16987
5mg43.00€10mg60.00€25mg118.00€50mg215.00€100mg319.00€200mg444.00€1mL*10mM (DMSO)47.00€BMS582949
CAS:BMS-582949 inhibits p38 MAPK with 13 nM IC50, blocking kinase activity and activation.Formula:C22H26N6O2Purity:98.11%Color and Shape:SolidMolecular weight:406.48Ref: TM-T6789
1mg82.00€2mg114.00€5mg200.00€10mg284.00€25mg477.00€50mg692.00€100mg973.00€1mL*10mM (DMSO)200.00€RAF709
CAS:RAF709 is a novel Raf kinase inhibitor with IC50s of 0.5 and 1.8 nM for c-Raf and b-Raf, respectively.Formula:C28H29F3N4O4Purity:99.28% - 99.8%Color and Shape:SolidMolecular weight:542.55Ref: TM-T3711
1mg38.00€2mg50.00€5mg82.00€10mg124.00€25mg245.00€50mg401.00€100mg592.00€500mg1,243.00€1mL*10mM (DMSO)88.00€AZD8330
CAS:AZD8330 (ARRY-704) is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.Formula:C16H17FIN3O4Purity:98.72%Color and Shape:SolidMolecular weight:461.23NG25
CAS:NG25 is a potent dual TAK1 and MAP4K2 inhibitor, with IC50s of 149 nM and 21.7 nM, respectively.Formula:C29H30F3N5O2Purity:98.32% - ≥95%Color and Shape:SolidMolecular weight:537.58XMD17-109
CAS:XMD17-109 (ERK5-IN-1) is a new selective ERK-5 inhibitor (EC50: 4.2 uM, HEK293 cells).
Formula:C36H46N8O3Purity:98.75% - 99.7%Color and Shape:SolidMolecular weight:638.8GSK-114
CAS:GSK-114, a TNNI3K inhibitor with a 25 nM IC50, is 40x more selective than B-Raf and good for in vivo studies.Formula:C19H23N5O4SPurity:99.51%Color and Shape:SolidMolecular weight:417.48ASP2453
CAS:ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C.Formula:C40H48F3N7O4Purity:99.71%Color and Shape:SolidMolecular weight:747.85Temuterkib
CAS:LY3214996 (Temuterkib) is a potent oral ERK1/2 inhibitor with potential cancer-fighting properties.
Formula:C22H27N7O2SPurity:99.57% - >99.99%Color and Shape:SolidMolecular weight:453.56Cefotetan
CAS:Cefotetan, a cephamycin antibiotic, fights various bacteria by disrupting cell wall synthesis.Formula:C17H17N7O8S4Purity:95.72% - 99.38%Color and Shape:SolidMolecular weight:575.62Talmapimod
CAS:Talmapimod (SCIO-469): Oral ATP-competitive p38α inhibitor, IC50 = 9 nM (p38α), 90 nM (p38β), >2000-fold selectivity over 20 kinases.Formula:C27H30ClFN4O3Purity:98% - 99.9%Color and Shape:SolidMolecular weight:513Ref: TM-T12871
1mg50.00€2mg73.00€5mg109.00€10mg168.00€25mg358.00€50mg530.00€100mg758.00€1mL*10mM (DMSO)124.00€Pyridoxal 5'-phosphate hydrate
CAS:Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions,Formula:C8H10NO6PPurity:97.52%Color and Shape:SolidMolecular weight:247.14(S)-AMG-510
CAS:(S)-AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C.Cost-effective and quality-assured.Formula:C30H30F2N6O3Purity:99.05% - 99.76%Color and Shape:SolidMolecular weight:560.594Ref: TM-T22258
2mg34.00€5mg50.00€10mg80.00€25mg147.00€50mg259.00€100mg404.00€500mg888.00€1mL*10mM (DMSO)73.00€ASK1-IN-1
CAS:ASK1-IN-1 inhibits apoptosis kinase 1, crucial in cell stress responses, with 21 nM IC50.Formula:C19H19N9O2Purity:99.92%Color and Shape:SolidMolecular weight:405.41Ref: TM-T9697
1mg90.00€5mg215.00€10mg321.00€25mg582.00€50mg873.00€100mg1,216.00€1mL*10mM (DMSO)236.00€AS601245
CAS:AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties.Formula:C20H16N6SPurity:98% - 99.02%Color and Shape:SolidMolecular weight:372.45PLX-4720
CAS:PLX-4720 is a potent and selective B-Raf (V600E) inhibitor designed to block the ATP-binding site of oncogenic B-Raf.Cost-effective and quality-assured.Formula:C17H14ClF2N3O3SPurity:97.78% - 99.83%Color and Shape:SolidMolecular weight:413.83Compound 3344 hydrochloride
Compound 3344 hydrochloride is an inhibitor of KRAS-effector interactions，with an affnity of 126nm.Formula:C24H27ClN2O3Purity:99.23%Color and Shape:SolidMolecular weight:426.94Ref: TM-T9184L
1mg136.00€5mg269.00€10mg404.00€25mg665.00€50mg888.00€100mg1,243.00€1mL*10mM (DMSO)318.00€CC-90001
CAS:CC-90001 is an orally administered c-Jun N-terminal kinase (JNK) inhibitor with bias for JNK1 over JNK2.Formula:C16H27N5O2Purity:99.96%Color and Shape:SolidMolecular weight:321.42
