MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
Found 893 products of "MAPK"
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CK1-IN-1
CAS:CK1-IN-1, a CK1 inhibitor with IC50: 15nM CK1δ, 16nM CK1ε, 73nM p38σ; patent WO2015119579A1.Formula:C24H15F2N3Purity:98.79%Color and Shape:SolidMolecular weight:383.39Ref: TM-T5393
1mg47.00€2mg62.00€5mg92.00€10mg152.00€25mg289.00€50mg447.00€100mg670.00€1mL*10mM (DMSO)101.00€GSK-114
CAS:GSK-114, a TNNI3K inhibitor with a 25 nM IC50, is 40x more selective than B-Raf and good for in vivo studies.Formula:C19H23N5O4SPurity:99.51%Color and Shape:SolidMolecular weight:417.48SCH54292
CAS:SCH-54292 is a GDP exchange inhibitor.Formula:C24H28N2O9SPurity:95.65%Color and Shape:SolidMolecular weight:520.55Compound 3344 hydrochloride
Compound 3344 hydrochloride is an inhibitor of KRAS-effector interactions，with an affnity of 126nm.Formula:C24H27ClN2O3Purity:99.23%Color and Shape:SolidMolecular weight:426.94Ref: TM-T9184L
1mg136.00€5mg269.00€10mg404.00€25mg665.00€50mg888.00€100mg1,243.00€1mL*10mM (DMSO)318.00€BMS582949
CAS:BMS-582949 inhibits p38 MAPK with 13 nM IC50, blocking kinase activity and activation.Formula:C22H26N6O2Purity:98.11%Color and Shape:SolidMolecular weight:406.48Ref: TM-T6789
1mg82.00€2mg114.00€5mg200.00€10mg284.00€25mg477.00€50mg692.00€100mg973.00€1mL*10mM (DMSO)200.00€Deltarasin HCl
CAS:Deltarasin hinders KRAS-PDEδ, impairs cancer cell growth via a PDEδ pocket, disrupting RAS/RAF signaling and autophagy.Formula:C40H37N5O·xHClColor and Shape:SolidMolecular weight:713.144SB 239063
CAS:SB 239063 (SB239063) is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 nM, showing no activity against the γ- and δ-kinase isoforms.
Formula:C20H21FN4O2Purity:99.42% - 99.81%Color and Shape:SolidMolecular weight:368.4p-Cresyl sulfate potassium
CAS:p-Cresyl sulfate potassium (p-Tolyl sulfate potassium salt) is a prototype protein-bound uremic toxin derived from the metabolites of tyrosine and phenylalanineFormula:C7H7KO4SPurity:99.38% - 99.90%Color and Shape:SolidMolecular weight:226.29ZT-12-037-01
CAS:Zt-12-037-01 is a ATP competitive STK19 inhibitor（IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).Formula:C21H31N5O2Purity:99.56%Color and Shape:SolidMolecular weight:385.5Talmapimod
CAS:Talmapimod (SCIO-469): Oral ATP-competitive p38α inhibitor, IC50 = 9 nM (p38α), 90 nM (p38β), >2000-fold selectivity over 20 kinases.Formula:C27H30ClFN4O3Purity:98% - 99.9%Color and Shape:SolidMolecular weight:513Ref: TM-T12871
1mg50.00€2mg73.00€5mg109.00€10mg168.00€25mg358.00€50mg530.00€100mg758.00€1mL*10mM (DMSO)124.00€Rasarfin
CAS:Rasarfin inhibits Ras and ARF6.Formula:C23H24ClN3O3Purity:97.98%Color and Shape:SolidMolecular weight:425.91Ref: TM-T9407
1mg38.00€5mg75.00€10mg110.00€25mg193.00€50mg323.00€100mg460.00€200mg620.00€1mL*10mM (DMSO)84.00€KRPEP-2D acetate
KRPEP-2D acetate: inhibitor targeting K-Ras(G12D) mutant, a crucial cancer-related protein.Formula:C110H186N44O27S2Purity:98.94%Color and Shape:SolidMolecular weight:2621.06APS6-45
CAS:APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.Formula:C23H16F8N4O3Purity:99.39%Color and Shape:SolidMolecular weight:548.39Ref: TM-T8843
2mg37.00€5mg84.00€10mg120.00€25mg236.00€50mg380.00€100mg583.00€200mg785.00€1mL*10mM (DMSO)92.00€GW 284543 hydrochloride
CAS:GW 284543 hydrochloride is a selective inhibitor of MEK5 .Formula:C23H21ClN2O3Purity:99.73%Color and Shape:SolidMolecular weight:408.87CMPD1
CAS:CMPD1 is a non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation inhibitor(apparent Ki (Kiapp): 330 nM).Formula:C22H20FNO2Purity:99.8%Color and Shape:SolidMolecular weight:349.4Ref: TM-T14988
1mg37.00€5mg104.00€10mg160.00€25mg281.00€50mg442.00€100mg685.00€500mg1,605.00€1mL*10mM (DMSO)114.00€Belvarafenib TFA
Belvarafenib TFA (HM95573 TFA) inhibits RAF: B-RAF (56 nM), B-RAFv600E (7 nM), C-RAF (5 nM) effectively.Formula:C25H17ClF4N6O3SColor and Shape:SolidMolecular weight:592.95JNK-IN-8
CAS:JNK-IN-8 (JNK Inhibitor XVI) is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM).Formula:C29H29N7O2Purity:99.24% - >99.99%Color and Shape:SolidMolecular weight:507.59Ref: TM-T2668
2mg47.00€5mg77.00€10mg119.00€25mg207.00€50mg344.00€100mg510.00€200mg722.00€1mL*10mM (DMSO)87.00€ARS-1620
CAS:ARS-1620 is a covalent inhibitor of K-RASG12C.Formula:C21H17ClF2N4O2Purity:98.86%Color and Shape:SolidMolecular weight:430.84K-Ras-IN-1
CAS:K-Ras-IN-1 is a K-Ras inhibitor.Formula:C11H13NOSPurity:98.72%Color and Shape:SolidMolecular weight:207.29DB07268
CAS:DB07268 is a potent and selective JNK1 inhibitor.Formula:C17H15N5O2Purity:98.2% - 98.91%Color and Shape:SolidMolecular weight:321.33
