MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
Found 881 products of "MAPK"
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AS601245
CAS:<p>AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties.</p>Formula:C20H16N6SPurity:98% - 99.02%Color and Shape:SolidMolecular weight:372.45AD80
CAS:<p>AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.</p>Formula:C22H19F4N7OPurity:99.49% - 99.75%Color and Shape:SolidMolecular weight:473.43K-Ras(G12C) inhibitor 6
CAS:<p>Irreversible K-Ras(G12C) inhibitor 6 fully modifies the protein at 10 μM after 24h in vitro.</p>Formula:C17H22Cl2N2O3SPurity:89.07% - 97.09%Color and Shape:SolidMolecular weight:405.34Cerdulatinib hydrochloride
CAS:<p>Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.</p>Formula:C20H28ClN7O3SPurity:99.85%Color and Shape:SolidMolecular weight:482ERK-IN-4
CAS:<p>ERK-IN-4 is a cell-permeable ERK inhibitor with potential antiproliferative effects for the study of diseases caused by immune dysfunction.</p>Formula:C14H17ClN2O3SPurity:98.92% - 99.84%Color and Shape:SolidMolecular weight:328.814Raf inhibitor 1
CAS:<p>B-Raf inhibitor 1 (B-Raf inhibitor 1) is a potent and selective B-Raf inhibitor.</p>Formula:C26H19ClN8Purity:98.05%Color and Shape:SolidMolecular weight:478.94GW284543
CAS:<p>GW284543 (UNC10225170) is a selective inhibitor of MEK5 .</p>Formula:C23H20N2O3Purity:99.75%Color and Shape:SolidMolecular weight:372.42Ulixertinib hydrochloride
CAS:<p>Ulixertinib hydrochloride (Ulixertinib HCl) is an ERK1/2 inhibitor with anticancer and antitumor activity that inhibits the NB cell cycle and promotes apoptosis</p>Formula:C21H23Cl3N4O2Purity:99.85%Color and Shape:SolidMolecular weight:469.79TBAP-001
CAS:TBAP-001 is a RAF kinase inhibitor, with an IC50 of 62 nM in BRAF V600E kinase assay and an IC50 of 18 nM in Cell-Based Phosho-ERK Assay.Formula:C27H23F2N7O3Purity:99.58%Color and Shape:SolidMolecular weight:531.51VX-702
CAS:<p>VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.</p>Formula:C19H12F4N4O2Purity:99% - >99.99%Color and Shape:SolidMolecular weight:404.32NCB-0846
CAS:<p>NCB-0846 is an orally active TNIK inhibitor (IC50: 21 nM).</p>Formula:C21H21N5O2Purity:97.04% - 99.89%Color and Shape:SolidMolecular weight:375.42AZD0022
CAS:AZD0022 is a selective, reversible, and orally active KRAS G12D inhibitor, exhibits tumour marker inhibition in PDAC and NSCLC models.Formula:C34H30F4N6OPurity:98.73%Color and Shape:SoildMolecular weight:614.64Trametiglue
CAS:<p>Trametiglue, a potent Trametinib derivative, selectively targets KSR-MEK and RAF-MEK through unique binding.</p>Formula:C25H24FIN6O5SColor and Shape:SolidMolecular weight:666.46AMG410
CAS:<p>AMG410 is a non-covalent, dual-modality KRAS inhibitor effective against both GDP (OFF) and GTP (ON) binding independently of the cell cycle and other mutants,</p>Formula:C31H32ClF2N7O5Purity:98.01% - 99.84%Color and Shape:SoildMolecular weight:656.08Cephradine monohydrate
CAS:<p>Cephradine monohydrate is a β-lactam cephalosporin antibiotic exhibiting broad-spectrum activity against Gram-positive and Gram-negative pathogens.</p>Formula:C16H21N3O5SPurity:99.91%Color and Shape:SolidMolecular weight:367.42Deltarasin
CAS:<p>Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.</p>Formula:C40H37N5OPurity:99.4%Color and Shape:SolidMolecular weight:603.75ETC-168
CAS:<p>ETC-168 is a selective, orally active MNK inhibitor with IC50 values of 23 nM for MNK1 and 43 nM for MNK2. It demonstrates antiproliferative efficacy both in vivo and in vitro [1].</p>Formula:C24H19N5O2Color and Shape:SolidMolecular weight:409.446H05
CAS:<p>6H05 (K-Ras inhibitor) is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).</p>Formula:C20H30ClN3O2S3Purity:98%Color and Shape:SolidMolecular weight:476.12SC-68376
CAS:<p>SC-68376 is a potent, reversible, cell-permeable, ATP-competitive, and selective inhibitor of p38 MAP kinase.</p>Formula:C15H12N2OPurity:98%Color and Shape:SolidMolecular weight:236.27FMK
CAS:<p>FMK 是一种不可逆的 RSK2 抑制剂，能够共价修饰 RSK 的 C 末端区域。</p>Formula:C18H19FN4O2Purity:99.71%Color and Shape:SolidMolecular weight:342.37
