MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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PLX8394
CAS:1393466-87-9
Plixorafenib (PLX8394) is an orally active inhibitor of the serine/threonine protein kinase B-Raf (BRAF) protein.Cost-effective …
Formula:
C25H21F3N6O3S
Purity:
100% - 98.22%
Color and Shape:
Solid
Molecular weight:
542.53
Ref: TM-T3579
| 1mg | 52.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 139.00 € | ||
| 25mg | 242.00 € | ||
| 50mg | 360.00 € | ||
| 100mg | 525.00 € | ||
| 1mL*10mM (DMSO) | 120.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
S6K-18
CAS:1265789-88-5
S6K-18, a highly selective S6K1 inhibitor, inhibits S6K1 with IC50 of 52nM.
Formula:
C17H18N4O3S
Purity:
99.23%
Color and Shape:
Solid
Molecular weight:
358.41
Ref: TM-T22422
| 1mg | 41.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 313.00 € | ||
| 50mg | 436.00 € | ||
| 100mg | 604.00 € | ||
| 200mg | 812.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Prunetin
CAS:552-59-0
Prunetin reduces inflammation, mortality, obesity markers, and mucin secretion, while blocking NF-κB, ERK activation, and …
Formula:
C16H12O5
Purity:
98.43% - ≥95%
Color and Shape:
Creamy White Crystalline Powder
Molecular weight:
284.26
Ref: TM-T4S0878
| 1mg | 46.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 245.00 € | ||
| 50mg | 367.00 € | ||
| 100mg | 547.00 € | ||
| 200mg | 783.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Isorhamnetin
CAS:480-19-3
Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin.
Formula:
C16H12O7
Purity:
92.82% - 98.97%
Color and Shape:
Solid
Molecular weight:
316.26
Ref: TM-T2836
| 1mg | 40.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 230.00 € | ||
| 50mg | 386.00 € | ||
| 100mg | 548.00 € | ||
| 500mg | 1,179.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tetrahydrocoptisine
CAS:4312-32-7
Tetrahydrocoptisine (Stylopine) quells inflammation, protects against ALI, guards the gut, and blocks key pro-inflammatory pathways.
Formula:
C19H17NO4
Purity:
99.71% - ≥95%
Color and Shape:
Solid
Molecular weight:
323.34
Ref: TM-T4S2063
| 1mg | 52.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 245.00 € | ||
| 50mg | 362.00 € | ||
| 100mg | 533.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ERK-IN-3
CAS:2055597-12-9
ERK-IN-3 (ASN007 free base) is a potent and orally active inhibitor of ERK.
Formula:
C22H25ClFN7O2
Purity:
99.55% - 99.76%
Color and Shape:
Solid
Molecular weight:
473.93
Ref: TM-T9141
| 1mg | 60.00 € | ||
| 5mg | 122.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 280.00 € | ||
| 50mg | 457.00 € | ||
| 1mL*10mM (DMSO) | 124.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Isomerazin
CAS:1088-17-1
Isomerazin (Isomeranzin) has anti-inflammatory activity, it suppresses inflammation by inhibiting M1 macrophage polarization through the …
Formula:
C15H16O4
Purity:
99.8%
Color and Shape:
Solid
Molecular weight:
260.29
Ref: TM-TN1786
| 1mg | 95.00 € | ||
| 5mg | 244.00 € | ||
| 10mg | 360.00 € | ||
| 25mg | 593.00 € | ||
| 50mg | 833.00 € | ||
| 1mL*10mM (DMSO) | 221.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Binimetinib
CAS:606143-89-9
Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has …
Formula:
C17H15BrF2N4O3
Purity:
100% - 99%
Color and Shape:
Solid
Molecular weight:
441.23
Ref: TM-T2508
| 5mg | 41.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 74.00 € | ||
| 50mg | 86.00 € | ||
| 100mg | 94.00 € | ||
| 200mg | 149.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tizoxanide
CAS:173903-47-4
Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.
Formula:
C10H7N3O4S
Purity:
100% - 99.28%
Color and Shape:
Solid
Molecular weight:
265.25
Ref: TM-T2279
| 5mg | 50.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 143.00 € | ||
| 50mg | 218.00 € | ||
| 100mg | 322.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tomivosertib
CAS:1849590-01-7
Tomivosertib (eFT508) is a potent, highly selective MNK1 and MNK2 inhibitor with IC50 value of …
Formula:
C17H20N6O2
Purity:
97.34% - 99.67%
Color and Shape:
Solid
Molecular weight:
340.38
Ref: TM-T3468
| 1mg | 64.00 € | ||
| 5mg | 166.00 € | ||
| 10mg | 238.00 € | ||
| 25mg | 446.00 € | ||
| 50mg | 644.00 € | ||
| 100mg | 916.00 € | ||
| 1mL*10mM (DMSO) | 179.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
APS6-45
CAS:2188236-41-9
APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.
Formula:
C23H16F8N4O3
Purity:
99.39%
Color and Shape:
Solid
Molecular weight:
548.39
Ref: TM-T8843
| 2mg | 39.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 125.00 € | ||
| 25mg | 247.00 € | ||
| 50mg | 397.00 € | ||
| 100mg | 593.00 € | ||
| 200mg | 799.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
GW 284543 hydrochloride
CAS:179246-08-3
GW 284543 hydrochloride is a selective inhibitor of MEK5 .
Formula:
C23H21ClN2O3
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
408.87
Ref: TM-T7742
| 1mg | 56.00 € | ||
| 2mg | 73.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 168.00 € | ||
| 25mg | 313.00 € | ||
| 50mg | 532.00 € | ||
| 100mg | 728.00 € | ||
| 200mg | 935.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
trans-Zeatin
CAS:1637-39-4
trans-Zeatin ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which …
Formula:
C10H13N5O
Purity:
97.13% - 98%
Color and Shape:
White To Light Yellow Crystal Powder
Molecular weight:
219.24
Ref: TM-TMS2181
| 25mg | 54.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PF-4708671
CAS:1255517-76-0
PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) .In cell-free assays, …
Formula:
C19H21F3N6
Purity:
99.48% - 99.67%
Color and Shape:
Solid
Molecular weight:
390.41
Ref: TM-T2002
| 5mg | 56.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 114.00 € | ||
| 50mg | 153.00 € | ||
| 100mg | 266.00 € | ||
| 1mL*10mM (DMSO) | 84.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Pimasertib
CAS:1236699-92-5
Pimasertib (AS703026) is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential …
Formula:
C15H15FIN3O3
Purity:
98.15% - 98.25%
Color and Shape:
Solid
Molecular weight:
431.2
Ref: TM-T6131
| 2mg | 37.00 € | ||
| 5mg | 49.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 92.00 € | ||
| 50mg | 148.00 € | ||
| 100mg | 220.00 € | ||
| 200mg | 285.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BI-D1870
CAS:501437-28-1
BI-D1870 is a highly specific, blood-brain-permeable, and ATP-competitive inhibitor of the N-terminal AGC kinase domain …
Formula:
C19H23F2N5O2
Purity:
98% - 99.43%
Color and Shape:
Solid
Molecular weight:
391.42
Ref: TM-T6171
| 1mg | 52.00 € | ||
| 2mg | 77.00 € | ||
| 5mg | 134.00 € | ||
| 10mg | 203.00 € | ||
| 25mg | 329.00 € | ||
| 50mg | 464.00 € | ||
| 100mg | 647.00 € | ||
| 500mg | 1,351.00 € | ||
| 1mL*10mM (DMSO) | 117.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Skepinone-L
CAS:1221485-83-1
Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.
Formula:
C24H21F2NO4
Purity:
100% - 99.76%
Color and Shape:
Solid
Molecular weight:
425.42
Ref: TM-T6130
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 204.00 € | ||
| 50mg | 307.00 € | ||
| 100mg | 454.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ERK5-IN-2
CAS:1888305-96-1
ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 μM, 3 …
Formula:
C17H11BrFN3O2
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
388.19
Ref: TM-T5535
| 1mg | 48.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 166.00 € | ||
| 25mg | 281.00 € | ||
| 50mg | 422.00 € | ||
| 100mg | 610.00 € | ||
| 200mg | 838.00 € | ||
| 1mL*10mM (DMSO) | 139.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SLV-2436
CAS:2095704-43-9
SLV-2436 (SEL201-88) is a novel effective and ATP-competitive inhibitor of MNK1 and MNK2 (IC50: 10.8/5.4 …
Formula:
C19H15ClN4O
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
350.8
Ref: TM-T4424
| 1mg | 81.00 € | ||
| 2mg | 104.00 € | ||
| 5mg | 167.00 € | ||
| 10mg | 271.00 € | ||
| 25mg | 517.00 € | ||
| 50mg | 744.00 € | ||
| 100mg | 1,023.00 € | ||
| 1mL*10mM (DMSO) | 186.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Necrosulfonamide
CAS:1360614-48-7
(E)-Necrosulfonamide ((E)-Necrosulfonamide) is an inhibitor of necroptosis.
Formula:
C18H15N5O6S2
Purity:
98.85% - 99.49%
Color and Shape:
Solid
Molecular weight:
461.47
Ref: TM-T6904
| 5mg | 56.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 211.00 € | ||
| 100mg | 370.00 € | ||
| 500mg | 875.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
