MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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Pachymic acid
CAS:29070-92-6
Pachymic acid (3-O-Acetyltumulosic acid) is a natural product, and inhibits Akt and ERK signaling pathways.
Formula:
C33H52O5
Purity:
100% - 99.91%
Color and Shape:
White Powder
Molecular weight:
528.76
Ref: TM-T6S0619
| 1mg | 78.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 258.00 € | ||
| 25mg | 491.00 € | ||
| 50mg | 708.00 € | ||
| 100mg | 993.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Epiberberine
CAS:6873-09-2
1.
Formula:
C20H18NO4
Purity:
98.52% - 99.59%
Color and Shape:
Solid
Molecular weight:
336.36
Ref: TM-T5S2361
| 1mg | 36.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 180.00 € | ||
| 50mg | 337.00 € | ||
| 100mg | 478.00 € | ||
| 500mg | 1,068.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SKF-86002
CAS:72873-74-6
SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 …
Formula:
C16H12FN3S
Purity:
98% - 99.68%
Color and Shape:
Solid
Molecular weight:
297.35
Ref: TM-T2367
| 5mg | 49.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 136.00 € | ||
| 50mg | 194.00 € | ||
| 100mg | 287.00 € | ||
| 200mg | 406.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
APS-2-79 hydrochloride
CAS:2002381-31-7
APS-2-79 hydrochloride (APS-2-79 HCl) is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing …
Formula:
C23H21N3O3·HCl
Purity:
97.08% - 98.64%
Color and Shape:
Solid
Molecular weight:
423.89
Ref: TM-T6760
| 1mg | 43.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 106.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 402.00 € | ||
| 100mg | 563.00 € | ||
| 500mg | 1,203.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
MW-150
CAS:1628502-91-9
MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally …
Formula:
C24H23N5
Purity:
99.27% - ≥95%
Color and Shape:
Solid
Molecular weight:
381.47
Ref: TM-T5494
| 1mg | 39.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 151.00 € | ||
| 25mg | 302.00 € | ||
| 50mg | 449.00 € | ||
| 100mg | 647.00 € | ||
| 500mg | 1,379.00 € | ||
| 1mL*10mM (DMSO) | 113.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Dabrafenib Mesylate
CAS:1195768-06-9
Dabrafenib Mesylate (GSK2118436 Mesylate) is a B-Raf inhibitor(IC50s of 0.6 and 5.0 nM for RafV600E …
Formula:
C24H24F3N5O5S3
Purity:
99.45% - 99.62%
Color and Shape:
Solid
Molecular weight:
615.67
Ref: TM-T8474
| 5mg | 47.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 78.00 € | ||
| 50mg | 92.00 € | ||
| 100mg | 113.00 € | ||
| 500mg | 221.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Bohemine
CAS:189232-42-6
Bohemine is a cyclin-dependent kinase inhibitor.
Formula:
C18H24N6O
Purity:
99.09% - 99.53%
Color and Shape:
Solid
Molecular weight:
340.42
Ref: TM-T2029
| 5mg | 34.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 136.00 € | ||
| 100mg | 204.00 € | ||
| 200mg | 301.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Sotorasib
CAS:2296729-00-3
Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C.
Formula:
C30H30F2N6O3
Purity:
98% - 99.89%
Color and Shape:
Solid
Molecular weight:
560.59
Ref: TM-T8684
| 1g | 1,338.00 € | ||
| 1mg | 37.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 222.00 € | ||
| 50mg | 368.00 € | ||
| 100mg | 452.00 € | ||
| 500mg | 1,010.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Methylnissolin
CAS:73340-41-7
Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) is derived from Astragalus and has antibacterial and anti-cancer effects.
Formula:
C17H16O5
Purity:
99.68% - 99.98%
Color and Shape:
Solid
Molecular weight:
300.31
Ref: TM-TN2354
| 1mg | 87.00 € | ||
| 5mg | 198.00 € | ||
| 10mg | 305.00 € | ||
| 25mg | 513.00 € | ||
| 50mg | 732.00 € | ||
| 1mL*10mM (DMSO) | 185.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Rhoifolin
CAS:17306-46-6
Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.
Formula:
C27H30O14
Purity:
98.11% - 98.87%
Color and Shape:
Solid
Molecular weight:
578.52
Ref: TM-T2755
| 20mg | 116.00 € | ||
| 1mL*10mM (DMSO) | 98.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
β,β-Dimethylacrylshikonin
CAS:24502-79-2
β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) is a promising agent for developing an improved strategy for radiotherapy against tumors.
Formula:
C21H22O6
Purity:
93.42% - 98.86%
Color and Shape:
Solid
Molecular weight:
370.4
Ref: TM-T3S2344
| 20mg | 126.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Regorafenib Hydrochloride
CAS:835621-07-3
Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong …
Formula:
C21H16Cl2F4N4O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
519.28
Ref: TM-T8402
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 79.00 € | ||
| 50mg | 94.00 € | ||
| 100mg | 142.00 € | ||
| 500mg | 343.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
LY-364947
CAS:396129-53-6
LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGFβR-I.
Formula:
C17H12N4
Purity:
99.41% - 99.96%
Color and Shape:
Solid
Molecular weight:
272.3
Ref: TM-T2048
| 5mg | 69.00 € | ||
| 10mg | 86.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 254.00 € | ||
| 100mg | 365.00 € | ||
| 200mg | 547.00 € | ||
| 500mg | 858.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PH-797804
CAS:586379-66-0
PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold …
Formula:
C22H19BrF2N2O3
Purity:
97.79% - 98.96%
Color and Shape:
Solid
Molecular weight:
477.3
Ref: TM-T1974
| 1mg | 45.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 252.00 € | ||
| 50mg | 402.00 € | ||
| 100mg | 621.00 € | ||
| 500mg | 1,304.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
DMX-5804
CAS:2306178-56-1
DMX-5804 is a potent, selective MAP4K4 inhibitor, with an IC50 of 3 nM.DMX-5804 enhances cardiomyocyte …
Formula:
C21H19N3O3
Purity:
99.34%
Color and Shape:
Solid
Molecular weight:
361.39
Ref: TM-T5483
| 1mg | 104.00 € | ||
| 2mg | 151.00 € | ||
| 5mg | 230.00 € | ||
| 10mg | 369.00 € | ||
| 25mg | 620.00 € | ||
| 50mg | 877.00 € | ||
| 100mg | 1,194.00 € | ||
| 1mL*10mM (DMSO) | 257.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
FERULIC ACID METHYL ESTER
CAS:2309-07-1
FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. …
Formula:
C11H12O4
Purity:
99.66% - 99.87%
Color and Shape:
Solid
Molecular weight:
208.21
Ref: TM-TL0004
| 100mg | 34.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ulixertinib hydrochloride
CAS:1956366-10-1
Ulixertinib hydrochloride (Ulixertinib HCl) is an ERK1/2 inhibitor with anticancer and antitumor activity that inhibits …
Formula:
C21H23Cl3N4O2
Color and Shape:
Solid
Molecular weight:
469.79
Ref: TM-T7005L
| 2mg | 50.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 101.00 € | ||
| 25mg | 165.00 € | ||
| 50mg | 235.00 € | ||
| 100mg | 348.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Bakuchiol
CAS:10309-37-2
Bakuchiol: anti-tumor, anti-helminthic, DNA polymerase1 inhibitor, cytotoxic, and anti-bacterial, may prevent dental caries.
Formula:
C18H24O
Purity:
98.69% - 99.47%
Color and Shape:
Brownish Yellow Liquid Viscous
Molecular weight:
256.38
Ref: TM-T3400
| 20mg | 86.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SL327
CAS:305350-87-2
SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to …
Formula:
C16H12F3N3S
Purity:
100% - 99.74%
Color and Shape:
Solid
Molecular weight:
335.35
Ref: TM-T2708
| 5mg | 36.00 € | ||
| 10mg | 46.00 € | ||
| 25mg | 68.00 € | ||
| 50mg | 93.00 € | ||
| 100mg | 155.00 € | ||
| 1mL*10mM (DMSO) | 40.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
TAK-580
CAS:1096708-71-2
TAK-580 (MLN2480) is an oral, selective pan-Raf kinase inhibitor in Clinicalal trials.
Formula:
C17H12Cl2F3N7O2S
Purity:
99.25% - 99.77%
Color and Shape:
Solid
Molecular weight:
506.29
Ref: TM-T6895
| 1mg | 52.00 € | ||
| 2mg | 74.00 € | ||
| 5mg | 101.00 € | ||
| 10mg | 176.00 € | ||
| 25mg | 297.00 € | ||
| 50mg | 436.00 € | ||
| 100mg | 650.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
