MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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JIP-1 (153-163) acetate(438567-88-5 free base)
JNK peptide inhibitor. Mimics JIP-1 residues 153-163. Micromolar affinity, little effect on p38, ERK.
Formula:
C63H108N20O16
Purity:
100%
Color and Shape:
Solid
Molecular weight:
1401.65
Ref: TM-TP1897L1
| 1mg | 275.00 € | ||
| 5mg | 628.00 € | ||
| 10mg | 938.00 € | ||
| 25mg | 1,388.00 € | ||
| 50mg | 1,838.00 € | ||
| 100mg | 2,523.00 € | ||
| 200mg | 2,004.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Pluripotin
CAS:839707-37-8
Pluripotin (SC1) (SC1), which keep embryonic stem cell (ESC) self-renewal, is a dual inhibitor of …
Formula:
C27H25F3N8O2
Purity:
98.77% - 98.82%
Color and Shape:
Solid
Molecular weight:
550.53
Ref: TM-T6948
| 1mg | 35.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 91.00 € | ||
| 25mg | 145.00 € | ||
| 50mg | 215.00 € | ||
| 100mg | 345.00 € | ||
| 1mL*10mM (DMSO) | 79.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PD184161
CAS:212631-67-9
PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) …
Formula:
C17H13BrClF2IN2O2
Purity:
99.09%
Color and Shape:
Solid
Molecular weight:
557.56
Ref: TM-T21635
| 1mg | 38.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 268.00 € | ||
| 50mg | 446.00 € | ||
| 100mg | 641.00 € | ||
| 200mg | 920.00 € | ||
| 500mg | 1,379.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BAY885
CAS:2307249-33-6
BAY885 is a new ERK5 inhibitor.
Formula:
C25H28F3N7O2
Purity:
99.83%
Color and Shape:
Solid
Molecular weight:
515.53
Ref: TM-T10479
| 1mg | 49.00 € | ||
| 5mg | 155.00 € | ||
| 10mg | 255.00 € | ||
| 25mg | 561.00 € | ||
| 50mg | 904.00 € | ||
| 1mL*10mM (DMSO) | 171.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Mogrol
CAS:88930-15-8
Mogrol, a biometabolite of mogrosides, functions by inhibiting the ERK1/2 and STAT3 pathways, diminishing CREB …
Formula:
C30H52O4
Purity:
98.21% - 99.85%
Color and Shape:
Solid
Molecular weight:
476.73
Ref: TM-TN2346
| 1mg | 37.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 178.00 € | ||
| 50mg | 266.00 € | ||
| 100mg | 393.00 € | ||
| 500mg | 894.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
LY3009120
CAS:1454682-72-4
LY3009120 (DP-4978) is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and …
Formula:
C23H29FN6O
Purity:
96.96% - ≥95%
Color and Shape:
Solid
Molecular weight:
424.51
Ref: TM-T6882
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 168.00 € | ||
| 50mg | 306.00 € | ||
| 100mg | 516.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Raf inhibitor 2
CAS:220904-99-4
Raf inhibitor 2 (CID 25014542) is novel inhibitor of Raf kinases.
Formula:
C15H8Br2ClNO2
Purity:
98.53%
Color and Shape:
Solid
Molecular weight:
429.49
Ref: TM-T4194
| 2mg | 39.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 159.00 € | ||
| 50mg | 232.00 € | ||
| 100mg | 337.00 € | ||
| 200mg | 474.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Theaflavin 3,3'-digallate
CAS:30462-35-2
Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of …
Formula:
C43H32O20
Purity:
98.71% - 99.86%
Color and Shape:
Solid
Molecular weight:
868.7
Ref: TM-T5429
| 1mg | 91.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 276.00 € | ||
| 25mg | 488.00 € | ||
| 50mg | 695.00 € | ||
| 100mg | 922.00 € | ||
| 1mL*10mM (DMSO) | 280.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
6H05 (TFA)
CAS:2061344-88-3
6H05 TFA (6H05 trifluoroacetate) is a selective, and allosteric oncogenic mutant K-Ras(G12C) inhibitor.
Formula:
C22H31ClF3N3O4S3
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
590.14
Ref: TM-T7326
| 1mg | 68.00 € | ||
| 2mg | 94.00 € | ||
| 5mg | 131.00 € | ||
| 10mg | 225.00 € | ||
| 25mg | 369.00 € | ||
| 50mg | 559.00 € | ||
| 100mg | 789.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Regorafenib
CAS:755037-03-7
Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, …
Formula:
C21H15ClF4N4O3
Purity:
98% - 99.95%
Color and Shape:
Solid
Molecular weight:
482.82
Ref: TM-T1792
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 79.00 € | ||
| 50mg | 94.00 € | ||
| 100mg | 142.00 € | ||
| 200mg | 181.00 € | ||
| 500mg | 304.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ASP2453
CAS:2241719-73-1
ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C.
Formula:
C40H48F3N7O4
Purity:
96.57%
Color and Shape:
Liquid
Molecular weight:
747.85
Ref: TM-T39738
| 1mg | 114.00 € | ||
| 5mg | 277.00 € | ||
| 10mg | 418.00 € | ||
| 25mg | 649.00 € | ||
| 50mg | 872.00 € | ||
| 1mL*10mM (DMSO) | 432.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Dabrafenib
CAS:1195765-45-7
Dabrafenib (GSK2118436A) is a Raf inhibitor that inhibits C-Raf and B-RafV600E (IC50=5/0.6 nM) and is …
Formula:
C23H20F3N5O2S2
Purity:
100% - 99.83%
Color and Shape:
Solid
Molecular weight:
519.56
Ref: TM-T1903
| 5mg | 48.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 78.00 € | ||
| 50mg | 92.00 € | ||
| 100mg | 113.00 € | ||
| 200mg | 153.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BIX02189
CAS:1265916-41-3
BIX02189 is a potent and selective inhibitor of MEK5 and ERK5(IC50 : 1.5 nM and …
Formula:
C27H28N4O2
Purity:
97.84%
Color and Shape:
Solid
Molecular weight:
440.54
Ref: TM-T21295
| 2mg | 34.00 € | ||
| 5mg | 49.00 € | ||
| 10mg | 72.00 € | ||
| 25mg | 122.00 € | ||
| 50mg | 203.00 € | ||
| 100mg | 301.00 € | ||
| 200mg | 435.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tenuifoliside A
CAS:139726-35-5
Tenuifoliside A has anti-apoptotic , neuroprotective activity.
Formula:
C31H38O17
Purity:
98.99% - 99.91%
Color and Shape:
Solid
Molecular weight:
682.62
Ref: TM-T3856
| 1mg | 60.00 € | ||
| 5mg | 124.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 308.00 € | ||
| 50mg | 461.00 € | ||
| 100mg | 643.00 € | ||
| 1mL*10mM (DMSO) | 172.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PD98059
CAS:167869-21-8
PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.
Formula:
C16H13NO3
Purity:
100% - 99.66%
Color and Shape:
Yellow Solid
Molecular weight:
267.28
Ref: TM-T2623
| 5mg | 45.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 88.00 € | ||
| 50mg | 111.00 € | ||
| 100mg | 183.00 € | ||
| 200mg | 269.00 € | ||
| 500mg | 449.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Meranzin hydrate
CAS:5875-49-0
Meranzin hydrate acts as an antidepressant and aids digestion, targeting α2-adrenoceptors and AMPA receptors, hastened …
Formula:
C15H18O5
Purity:
99.49%
Color and Shape:
Solid
Molecular weight:
278.3
Ref: TM-TN1922
| 1mg | 96.00 € | ||
| 5mg | 212.00 € | ||
| 10mg | 318.00 € | ||
| 25mg | 532.00 € | ||
| 50mg | 756.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SR-318
CAS:2413286-32-3
SR-318 inhibits TNF-α (IC50=283 nM), selectively targets p38 MAPK: IC50 of 5nM (p38α), 32nM (p38β), …
Formula:
C27H33N5O2
Purity:
99.53%
Color and Shape:
Solid
Molecular weight:
459.58
Ref: TM-T12997
| 2mg | 37.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 171.00 € | ||
| 50mg | 266.00 € | ||
| 100mg | 382.00 € | ||
| 200mg | 548.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Decursinol angelate
CAS:130848-06-5
Decursinol angelate is anti-tumor, anti-inflammatory, anti-oxidant, hepatoprotective, and inhibits VEGF and cancer cell invasion.
Formula:
C19H20O5
Purity:
99.93%
Color and Shape:
Solid
Molecular weight:
328.36
Ref: TM-TN1557
| 5mg | 50.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 144.00 € | ||
| 50mg | 207.00 € | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
TA-02
CAS:1784751-19-4
TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.
Formula:
C20H13F2N3
Purity:
99.35% - 99.79%
Color and Shape:
Solid
Molecular weight:
333.33
Ref: TM-T4646
| 5mg | 39.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 103.00 € | ||
| 50mg | 157.00 € | ||
| 100mg | 239.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ERK5-IN-1
CAS:1234479-76-5
ERK5-IN-1 is a potent ERK5 inhibitor (IC50: 87 nM). It also inhibits LRRK2[G2019S] (IC50: 26 …
Formula:
C25H29N7O2
Purity:
99.42%
Color and Shape:
Solid
Molecular weight:
459.54
Ref: TM-T5184
| 1mg | 52.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 167.00 € | ||
| 25mg | 241.00 € | ||
| 50mg | 326.00 € | ||
| 100mg | 456.00 € | ||
| 1mL*10mM (DMSO) | 120.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
