MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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Aurantiamide
CAS:58115-31-4
Aurantiamide inhibits cancer, inflammation, pain, and neuroinflammation by blocking autophagy and NF-κB, JNK, p38 pathways.
Formula:
C25H26N2O3
Purity:
98.88%
Color and Shape:
Solid
Molecular weight:
402.49
Ref: TM-T5814
| 1mg | 134.00 € | ||
| 5mg | 322.00 € | ||
| 10mg | 478.00 € | ||
| 25mg | 763.00 € | ||
| 50mg | 1,011.00 € | ||
| 100mg | 1,382.00 € | ||
| 1mL*10mM (DMSO) | 466.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
LY-2584702 free base
CAS:1082949-67-4
LY2584702 is a selective, ATP-competitive p70S6K inhibitor(IC50: 4 nM).
Formula:
C21H19F4N7
Purity:
98.04% - 98.72%
Color and Shape:
Solid
Molecular weight:
445.42
Ref: TM-T6159
| 1mg | 46.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 148.00 € | ||
| 25mg | 315.00 € | ||
| 50mg | 425.00 € | ||
| 100mg | 625.00 € | ||
| 200mg | 515.00 € | ||
| 500mg | 1,290.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Isoliquiritin apioside
CAS:120926-46-7
Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and …
Formula:
C26H30O13
Purity:
98.84% - 99.27%
Color and Shape:
Solid
Molecular weight:
550.51
Ref: TM-T3860
| 1mg | 53.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 280.00 € | ||
| 50mg | 428.00 € | ||
| 100mg | 616.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Prosaptide TX14(A) acetate
Prosaptide TX14(A) acetate is a potent GPR37L1 and GPR37 agonist. Prosaptide Tx14(A) TFA increases both …
Formula:
C71H114N16O28
Purity:
95.29%
Color and Shape:
Solid
Molecular weight:
1639.76
Ref: TM-TP1970L
| 1mg | 144.00 € | ||
| 5mg | 343.00 € | ||
| 10mg | 512.00 € | ||
| 25mg | 824.00 € | ||
| 50mg | 1,116.00 € | ||
| 100mg | 1,529.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ravoxertinib
CAS:1453848-26-4
Ravoxertinib (GDC-0994) is an effective and orally available ERK1/2 inhibitor (IC50: 1.1/0.3 nM).
Formula:
C21H18ClFN6O2
Purity:
98% - 99.87%
Color and Shape:
Solid
Molecular weight:
440.86
Ref: TM-T6511
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 171.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 412.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Doramapimod
CAS:285983-48-4
Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but …
Formula:
C31H37N5O3
Purity:
97.73% - 99.65%
Color and Shape:
Solid
Molecular weight:
527.66
Ref: TM-T6277
| 1g | 552.00 € | ||
| 5mg | 36.00 € | ||
| 10mg | 54.00 € | ||
| 25mg | 78.00 € | ||
| 50mg | 90.00 € | ||
| 100mg | 124.00 € | ||
| 200mg | 220.00 € | ||
| 500mg | 371.00 € | ||
| 1mL*10mM (DMSO) | 44.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
LY-2584702 tosylate salt
CAS:1082949-68-5
LY-2584702 tosylate salt is a selective, ATP-competitive p70S6K inhibitor, used in trials studying the treatment …
Formula:
C28H27F4N7O3S
Purity:
98.23% - 98.5%
Color and Shape:
Solid
Molecular weight:
617.62
Ref: TM-T1746
| 1mg | 37.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 352.00 € | ||
| 100mg | 500.00 € | ||
| 500mg | 1,072.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PRT062607 hydrochloride
CAS:1370261-97-4
PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk. PRT062607 displays at least 80-fold …
Formula:
C19H23N9O·HCl
Purity:
97.11% - 99.93%
Color and Shape:
Solid
Molecular weight:
429.91
Ref: TM-T2696
| 1mg | 61.00 € | ||
| 2mg | 84.00 € | ||
| 5mg | 127.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 327.00 € | ||
| 50mg | 500.00 € | ||
| 100mg | 406.00 € | ||
| 200mg | 946.00 € | ||
| 1mL*10mM (DMSO) | 140.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
LM22B-10
CAS:342777-54-2
LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor and can induce TrkB, TrkC, ERK and …
Formula:
C27H33ClN2O4
Purity:
98.19%
Color and Shape:
Solid
Molecular weight:
485.01
Ref: TM-T4496
| 1mg | 39.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 132.00 € | ||
| 25mg | 272.00 € | ||
| 50mg | 429.00 € | ||
| 100mg | 682.00 € | ||
| 1mL*10mM (DMSO) | 132.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PD318088
CAS:391210-00-7
PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binding simultaneously with ATP in a region …
Formula:
C16H13BrF3IN2O4
Purity:
99.81%
Color and Shape:
Solid
Molecular weight:
561.09
Ref: TM-T6152
| 1mg | 51.00 € | ||
| 5mg | 105.00 € | ||
| 10mg | 163.00 € | ||
| 25mg | 332.00 € | ||
| 50mg | 500.00 € | ||
| 100mg | 759.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
HPK1-IN-7
CAS:2320462-65-3
HPK1-IN-7 is an orally active HPK1 inhibitor. It shows selectivity against IRAK4 (59 nM) and …
Formula:
C24H22N6O4
Purity:
99.31%
Color and Shape:
Solid
Molecular weight:
458.47
Ref: TM-T9470
| 1mg | 82.00 € | ||
| 5mg | 167.00 € | ||
| 10mg | 266.00 € | ||
| 25mg | 433.00 € | ||
| 50mg | 593.00 € | ||
| 100mg | 817.00 € | ||
| 200mg | 1,080.00 € | ||
| 1mL*10mM (DMSO) | 167.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SB-590885
CAS:405554-55-4
SB590885 is an effective B-Raf inhibitor (Ki: 0.16 nM, in a cell-free assay).
Formula:
C27H27N5O2
Purity:
95.42% - 99.06%
Color and Shape:
Solid
Molecular weight:
453.54
Ref: TM-T2295
| 1mg | 43.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 129.00 € | ||
| 25mg | 249.00 € | ||
| 50mg | 477.00 € | ||
| 100mg | 697.00 € | ||
| 1mL*10mM (DMSO) | 145.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Neflamapimod
CAS:209410-46-8
Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity …
Formula:
C19H9Cl2F2N3OS
Purity:
99.02% - ≥95%
Color and Shape:
Solid
Molecular weight:
436.26
Ref: TM-T6089
| 5mg | 50.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 202.00 € | ||
| 100mg | 300.00 € | ||
| 200mg | 448.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SD-169
CAS:1670-87-7
SD-169 (SD 169) is a selective and ATP competitive the MAP kinases p38α and p38β …
Formula:
C9H8N2O
Purity:
98.60%
Color and Shape:
Solid
Molecular weight:
160.17
Ref: TM-T7661
| 25mg | 36.00 € | ||
| 50mg | 51.00 € | ||
| 100mg | 78.00 € | ||
| 200mg | 102.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
K-Ras-IN-1
CAS:84783-01-7
K-Ras-IN-1 is a K-Ras inhibitor.
Formula:
C11H13NOS
Purity:
98.72%
Color and Shape:
Solid
Molecular weight:
207.29
Ref: TM-T5469
| 2mg | 45.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 99.00 € | ||
| 25mg | 178.00 € | ||
| 50mg | 277.00 € | ||
| 100mg | 415.00 € | ||
| 200mg | 574.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
(S)-AMG-510
CAS:2252403-56-6
(S)-AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C.Cost-effective and …
Formula:
C30H30F2N6O3
Purity:
98.01% - 98.57%
Color and Shape:
Solid
Molecular weight:
560.59
Ref: TM-T22258
| 2mg | 36.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 152.00 € | ||
| 50mg | 268.00 € | ||
| 100mg | 420.00 € | ||
| 500mg | 917.00 € | ||
| 1mL*10mM (DMSO) | 77.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SUN11602
CAS:704869-38-5
SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor.
Formula:
C26H37N5O2
Purity:
98.43%
Color and Shape:
Solid
Molecular weight:
451.6
Ref: TM-T3714
| 5mg | 61.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 190.00 € | ||
| 50mg | 315.00 € | ||
| 100mg | 393.00 € | ||
| 1mL*10mM (DMSO) | 68.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Licochalcone D
CAS:144506-15-0
Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and …
Formula:
C21H22O5
Purity:
99.03%
Color and Shape:
Solid
Molecular weight:
354.4
Ref: TM-T4518
| 1mg | 94.00 € | ||
| 5mg | 222.00 € | ||
| 10mg | 322.00 € | ||
| 25mg | 535.00 € | ||
| 50mg | 763.00 € | ||
| 100mg | 1,011.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
MK2-IN-3
CAS:724711-21-1
MK2-IN-3 is a potent MK-2 inhibitor, cell-permeable, for rheumatoid arthritis treatment.
Formula:
C21H16N4O
Purity:
99.01%
Color and Shape:
Solid
Molecular weight:
340.38
Ref: TM-T9034
| 1mg | 39.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 249.00 € | ||
| 50mg | 365.00 € | ||
| 100mg | 520.00 € | ||
| 200mg | 709.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
(E/Z)-BIX02188
CAS:1094614-84-2
BIX02188 inhibits MEK5 (IC50: 4.3 nM) and ERK5 (810 nM) but not MEK1/2, JNK2, or …
Formula:
C25H24N4O2
Purity:
97.39% - 98.38%
Color and Shape:
Solid
Molecular weight:
412.48
Ref: TM-T6324
| 1mg | 51.00 € | ||
| 2mg | 65.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 226.00 € | ||
| 25mg | 341.00 € | ||
| 50mg | 512.00 € | ||
| 100mg | 737.00 € | ||
| 1mL*10mM (DMSO) | 142.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
