MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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MRTX1133
CAS:2621928-55-8
View and buy MRTX1133 from TargetMol.MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS …
Formula:
C33H31F3N6O2
Purity:
97.39% - 99.10%
Color and Shape:
Solid
Molecular weight:
600.63
Ref: TM-T9303
| 1mg | 185.00 € | ||
| 5mg | 397.00 € | ||
| 10mg | 607.00 € | ||
| 25mg | 932.00 € | ||
| 50mg | 1,318.00 € | ||
| 100mg | 1,794.00 € | ||
| 1mL*10mM (DMSO) | 523.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
TAK-733
CAS:1035555-63-5
TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic …
Formula:
C17H15F2IN4O4
Purity:
98.31% - 99.53%
Color and Shape:
Solid
Molecular weight:
504.23
Ref: TM-T6692
| 1mg | 55.00 € | ||
| 2mg | 79.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 196.00 € | ||
| 25mg | 352.00 € | ||
| 50mg | 521.00 € | ||
| 1mL*10mM (DMSO) | 132.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AMG 900
CAS:945595-80-2
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with …
Formula:
C28H21N7OS
Purity:
98.35% - 98.9%
Color and Shape:
Solid
Molecular weight:
503.58
Ref: TM-T6380
| 1mg | 52.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 163.00 € | ||
| 25mg | 295.00 € | ||
| 50mg | 457.00 € | ||
| 100mg | 670.00 € | ||
| 500mg | 1,384.00 € | ||
| 1mL*10mM (DMSO) | 103.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Bisabolangelone
CAS:30557-81-4
Bisabolangelone: anti-tumor, anti-inflammatory, anti-microbial, antioxidant, blocks MAPK/NF-κB in dendritic cells.
Formula:
C15H20O3
Purity:
98.91%
Color and Shape:
Solid
Molecular weight:
248.32
Ref: TM-TN1445
| 1mg | 52.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 158.00 € | ||
| 25mg | 258.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
KO-947
CAS:1695533-89-1
KO-947 is a potent and specific inhibitor of ERK1/2 kinases.
Formula:
C21H17N5O
Purity:
96.81%
Color and Shape:
Solid
Molecular weight:
355.39
Ref: TM-TQ0005
| 1mg | 51.00 € | ||
| 5mg | 100.00 € | ||
| 10mg | 159.00 € | ||
| 25mg | 313.00 € | ||
| 50mg | 501.00 € | ||
| 100mg | 791.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ML-098
CAS:878978-76-8
ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).
Formula:
C19H19NO3
Purity:
99.06% - 99.52%
Color and Shape:
Solid
Molecular weight:
309.36
Ref: TM-T4619
| 1mg | 39.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 196.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 386.00 € | ||
| 500mg | 913.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Epieriocalyxin A
CAS:191545-24-1
Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug …
Formula:
C20H24O5
Purity:
97.00%
Color and Shape:
Solid
Molecular weight:
344.4
Ref: TM-TN3967
| 1mg | 202.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SM-7368
CAS:380623-76-7
The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used …
Formula:
C10H5ClN4O5S
Purity:
99.64% - 99.64%
Color and Shape:
Solid
Molecular weight:
328.69
Ref: TM-T22115
| 5mg | 45.00 € | ||
| 10mg | 72.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 272.00 € | ||
| 200mg | 397.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BI-882370
CAS:1392429-79-6
BI-882370 is a specific RAF kinase inhibitor.
Formula:
C28H33F2N7O2S
Purity:
97.33% - 99.07%
Color and Shape:
Solid
Molecular weight:
569.67
Ref: TM-TQ0048
| 1mg | 42.00 € | ||
| 2mg | 56.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 132.00 € | ||
| 25mg | 231.00 € | ||
| 50mg | 414.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
NVP-BAW2881
CAS:861875-60-7
NVP-BAW2881 (BAW2881) is a potent and selective VEGFR inhibitor with activity to inhibit chronic and …
Formula:
C22H15F3N4O2
Purity:
98.19% - 99.97%
Color and Shape:
Solid
Molecular weight:
424.38
Ref: TM-T3641
| 1mg | 36.00 € | ||
| 2mg | 50.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 210.00 € | ||
| 50mg | 338.00 € | ||
| 100mg | 490.00 € | ||
| 500mg | 1,087.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
N-Feruloyloctopamine
CAS:66648-44-0
N-Feruloyloctopamine is a natural product.
Formula:
C18H19NO5
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
329.35
Ref: TM-TN1968
| 1mg | 88.00 € | ||
| 5mg | 203.00 € | ||
| 10mg | 297.00 € | ||
| 25mg | 500.00 € | ||
| 50mg | 723.00 € | ||
| 100mg | 1,013.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
1588-A4
CAS:1698027-20-1
1588-A4 (ARS-1620 Intermediate) is an intermediate of ARS-1620 which is an atropisomeric selective KRASG12C inhibitor …
Formula:
C17H19BrClFN4O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
445.71
Ref: TM-T22249
| 1mg | 81.00 € | ||
| 2mg | 93.00 € | ||
| 5mg | 152.00 € | ||
| 10mg | 214.00 € | ||
| 25mg | 356.00 € | ||
| 50mg | 509.00 € | ||
| 100mg | 692.00 € | ||
| 200mg | 903.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Raf inhibitor 1 dihydrochloride
CAS:1191385-19-9
Raf inhibitor 1 dihydrochloride (B-Raf inhibitor 1 dihydrochloride) is a potent and selective B-Raf inhibitor.
Formula:
C26H19ClN8HCl
Purity:
98.19% - 98.44%
Color and Shape:
Solid
Molecular weight:
551.86
Ref: TM-T4167
| 1mg | 49.00 € | ||
| 2mg | 65.00 € | ||
| 5mg | 105.00 € | ||
| 10mg | 182.00 € | ||
| 25mg | 304.00 € | ||
| 50mg | 450.00 € | ||
| 100mg | 659.00 € | ||
| 200mg | 542.00 € | ||
| 500mg | 1,347.00 € | ||
| 1mL*10mM (DMSO) | 190.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PLX-4720
CAS:918505-84-7
PLX-4720 is a potent and selective B-Raf (V600E) inhibitor designed to block the ATP-binding site …
Formula:
C17H14ClF2N3O3S
Purity:
97.78% - 99.89%
Color and Shape:
Solid
Molecular weight:
413.83
Ref: TM-T2473
| 5mg | 38.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 86.00 € | ||
| 50mg | 98.00 € | ||
| 100mg | 122.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Gypenoside L
CAS:94987-09-4
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through …
Formula:
C42H72O14
Purity:
99.42% - 99.65%
Color and Shape:
Solid
Molecular weight:
801.01
Ref: TM-TN1721
| 1mg | 124.00 € | ||
| 5mg | 290.00 € | ||
| 10mg | 369.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Deoxyelephantopin
CAS:29307-03-7
Deoxyelephantopin: anti-inflammatory, hepatoprotective, wound healing, antitumor; blocks NF-κB, MAPK, PI3K/Akt, β-catenin pathways.
Formula:
C19H20O6
Purity:
99.6% - 99.69%
Color and Shape:
Solid
Molecular weight:
344.36
Ref: TM-TN1079
| 1mg | 94.00 € | ||
| 5mg | 230.00 € | ||
| 10mg | 342.00 € | ||
| 25mg | 553.00 € | ||
| 50mg | 801.00 € | ||
| 1mL*10mM (DMSO) | 239.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Pamapimod
CAS:449811-01-2
Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.
Formula:
C19H20F2N4O4
Purity:
97.63% - 99.99%
Color and Shape:
Solid
Molecular weight:
406.38
Ref: TM-T6927
| 1mg | 55.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 369.00 € | ||
| 50mg | 595.00 € | ||
| 100mg | 833.00 € | ||
| 500mg | 1,672.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
RO4987655
CAS:874101-00-5
RO4987655 (RG7167) is an orally active and highly selective MEK inhibitor (IC50: 5.2 nM for …
Formula:
C20H19F3IN3O5
Purity:
98.21%
Color and Shape:
Solid
Molecular weight:
565.28
Ref: TM-T5412
| 1mg | 80.00 € | ||
| 2mg | 104.00 € | ||
| 5mg | 182.00 € | ||
| 10mg | 280.00 € | ||
| 25mg | 468.00 € | ||
| 50mg | 650.00 € | ||
| 100mg | 1,009.00 € | ||
| 1mL*10mM (DMSO) | 225.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BCI-215
CAS:1245792-67-9
BCI-215 causes selective cancer cell cytotoxicity in part through non-redox-mediated activation of MAPK signaling
Formula:
C22H22BrNO
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
396.32
Ref: TM-T7323
| 1mg | 49.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 265.00 € | ||
| 50mg | 417.00 € | ||
| 100mg | 606.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Lonafarnib
CAS:193275-84-2
Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 …
Formula:
C27H31Br2ClN4O2
Purity:
98% - 99.04%
Color and Shape:
Solid
Molecular weight:
638.82
Ref: TM-T6302
| 1mg | 48.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 292.00 € | ||
| 50mg | 462.00 € | ||
| 100mg | 646.00 € | ||
| 1mL*5mM (DMSO) | 164.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
