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MAPK

MAPK

MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.

Found 886 products of "MAPK"

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  • R1487
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    R1487

    CAS:
    <p>R1487 is an orally bioavailable and highly selective p38α mitogen-activated protein kinase inhibitor.</p>
    Formula:C19H18F2N4O3
    Purity:99.77%
    Color and Shape:Solid
    Molecular weight:388.37

    Ref: TM-T7667

  • SB 242235
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    SB 242235

    CAS:
    <p>SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.</p>
    Formula:C19H20FN5O
    Purity:99.13% - 99.68%
    Color and Shape:Solid
    Molecular weight:353.39

    Ref: TM-T4078

  • JNK-IN-8
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    JNK-IN-8

    CAS:
    <p>JNK-IN-8 (JNK Inhibitor XVI) is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM).</p>
    Formula:C29H29N7O2
    Purity:99.24% - >99.99%
    Color and Shape:Solid
    Molecular weight:507.59

    Ref: TM-T2668

  • GNE-495
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    GNE-495

    CAS:
    <p>GNE-495 is a potent and specific MAP4K4 inhibitor (IC50: 3.7 nM).</p>
    Formula:C22H20FN5O2
    Purity:99.22% - 99.57%
    Color and Shape:Solid
    Molecular weight:405.42

    Ref: TM-TQ0079

  • AS601245
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    AS601245

    CAS:
    <p>AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties.</p>
    Formula:C20H16N6S
    Purity:98% - 99.02%
    Color and Shape:Solid
    Molecular weight:372.45

    Ref: TM-T2343

  • sodium lauroyl-α-hydroxyethyl sulfonate
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    sodium lauroyl-α-hydroxyethyl sulfonate

    CAS:
    <p>Sodium houttuyfonate is anti-pseudomonas agents, inhibits virulence-related motility of Pseudomonas.</p>
    Formula:C14H27NaO5S
    Purity:≥98% - ≥98%
    Color and Shape:Solid
    Molecular weight:330.41

    Ref: TM-T7283

  • B-Raf IN 11
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    B-Raf IN 11

    CAS:
    <p>B-Raf IN 11 is a novel selective inhibitor.</p>
    Formula:C17H14BrF2N3O3S
    Purity:99.947%
    Color and Shape:Solid
    Molecular weight:458.28

    Ref: TM-T19802

  • Ro 5126766
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    Ro 5126766

    CAS:
    <p>RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM, 19 nM, 56 nM, and 160 nM for BRAF V600E, BRAF, CRAF, and MEK1, respectively. Phase 1.</p>
    Formula:C21H18FN5O5S
    Purity:98.3% - 98.81%
    Color and Shape:Solid
    Molecular weight:471.46

    Ref: TM-T6971

  • IQ-3
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    IQ-3

    CAS:
    <p>IQ3 inhibits JNK3 (Kd 66 nM), JNK1/2, NF-κB/AP1 in THP1-Blue cells (IC50 1.4 μM), and reduces TNF-α/IL-6 production.</p>
    Formula:C20H11N3O3
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:341.32

    Ref: TM-T8477

  • K-Ras(G12C) inhibitor 9
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    K-Ras(G12C) inhibitor 9

    CAS:
    <p>K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).</p>
    Formula:C16H21ClIN3O4S
    Purity:97.33% - 97.45%
    Color and Shape:Solid
    Molecular weight:513.78

    Ref: TM-T6556

  • SCH54292
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    SCH54292

    CAS:
    <p>SCH-54292 is a GDP exchange inhibitor.</p>
    Formula:C24H28N2O9S
    Purity:95.65%
    Color and Shape:Solid
    Molecular weight:520.55

    Ref: TM-T9198

  • SL327
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    SL327

    CAS:
    <p>SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to transport through the blood-brain barrier.</p>
    Formula:C16H12F3N3S
    Purity:97.98% - >99.99%
    Color and Shape:Solid
    Molecular weight:335.35

    Ref: TM-T2708

  • Vemurafenib
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    Vemurafenib

    CAS:
    <p>Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently.</p>
    Formula:C23H18ClF2N3O3S
    Purity:98% - 99.65%
    Color and Shape:Solid
    Molecular weight:489.92

    Ref: TM-T2382

  • CK1-IN-1
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    CK1-IN-1

    CAS:
    <p>CK1-IN-1, a CK1 inhibitor with IC50: 15nM CK1δ, 16nM CK1ε, 73nM p38σ; patent WO2015119579A1.</p>
    Formula:C24H15F2N3
    Purity:98.79%
    Color and Shape:Solid
    Molecular weight:383.39

    Ref: TM-T5393

  • TAK-715
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    TAK-715

    CAS:
    <p>TAK-715 is a p38 MAPK inhibitor for p38α.</p>
    Formula:C24H21N3OS
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:399.51

    Ref: TM-T6150

  • Maohuoside A
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    Maohuoside A

    CAS:
    <p>Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways.</p>
    Formula:C27H32O12
    Purity:98.91% - 99.57%
    Color and Shape:Solid
    Molecular weight:548.54

    Ref: TM-TN2081

  • DB07268
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    DB07268

    CAS:
    <p>DB07268 is a potent and selective JNK1 inhibitor.</p>
    Formula:C17H15N5O2
    Purity:98.2% - 98.91%
    Color and Shape:Solid
    Molecular weight:321.33

    Ref: TM-T3200

  • p-Cresyl sulfate potassium
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    p-Cresyl sulfate potassium

    CAS:
    <p>p-Cresyl sulfate potassium (p-Tolyl sulfate potassium salt) is a prototype protein-bound uremic toxin derived from the metabolites of tyrosine and phenylalanine</p>
    Formula:C7H7KO4S
    Purity:99.38%
    Color and Shape:Solid
    Molecular weight:226.29

    Ref: TM-T19498

  • XMD17-109
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    XMD17-109

    CAS:
    <p>XMD17-109 (ERK5-IN-1) is a new selective ERK-5 inhibitor (EC50: 4.2 uM, HEK293 cells).</p>
    Formula:C36H46N8O3
    Purity:98.75% - 99.7%
    Color and Shape:Solid
    Molecular weight:638.8

    Ref: TM-T1842

  • Rasarfin
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    Rasarfin

    CAS:
    <p>Rasarfin inhibits Ras and ARF6.</p>
    Formula:C23H24ClN3O3
    Purity:97.98%
    Color and Shape:Solid
    Molecular weight:425.91

    Ref: TM-T9407