MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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RWJ-67657
CAS:215303-72-3
RWJ-67657 is a selective oral p38α/β MAPK inhibitor with IC50s of 1/11μM; inactive on p38γ/δ …
Formula:
C27H24FN3O
Purity:
99.66%
Color and Shape:
Solid
Molecular weight:
425.5
Ref: TM-T16812
| 2mg | 46.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 214.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 557.00 € | ||
| 500mg | 1,161.00 € | ||
| 1mL*10mM (DMSO) | 76.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
β-Tocopherol
CAS:148-03-8
Beta-Tocopherol has effects on human erythroleukemia cell (HEL) adhesion induced by phorbol 12-myristate 13-acetate (PMA).Cost-effective …
Formula:
C28H48O2
Purity:
99.8% - 99.81%
Color and Shape:
Solid
Molecular weight:
416.68
Ref: TM-TN1441
| 1mg | 59.00 € | ||
| 2mg | 86.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 199.00 € | ||
| 25mg | 337.00 € | ||
| 50mg | 502.00 € | ||
| 1mL*10mM (DMSO) | 153.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Agerafenib
CAS:1188910-76-0
Agerafenib (CEP32496) is a highly potent inhibitor of BRAF.
Formula:
C24H22F3N5O5
Purity:
95.78% - 99.23%
Color and Shape:
Solid
Molecular weight:
517.46
Ref: TM-T2070
| 1mg | 42.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 128.00 € | ||
| 25mg | 227.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 553.00 € | ||
| 200mg | 790.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Avicularin
CAS:572-30-5
Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in …
Formula:
C20H18O11
Purity:
97.02% - 99.43%
Color and Shape:
White Powder
Molecular weight:
434.35
Ref: TM-T6S0117
| 1mg | 56.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 155.00 € | ||
| 25mg | 272.00 € | ||
| 1mL*10mM (DMSO) | 107.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SB 242235
CAS:193746-75-7
SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an …
Formula:
C19H20FN5O
Purity:
99.13% - 99.68%
Color and Shape:
Solid
Molecular weight:
353.39
Ref: TM-T4078
| 2mg | 47.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 232.00 € | ||
| 50mg | 353.00 € | ||
| 100mg | 531.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Locostatin
CAS:133812-16-5
Locostatin is a potent and cell permeable inhibitor of Raf kinase inhibitor protein (RKIP)/Raf1 kinase …
Formula:
C14H15NO3
Purity:
97.13%
Color and Shape:
Solid
Molecular weight:
245.27
Ref: TM-T8823
| 5mg | 46.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 110.00 € | ||
| 50mg | 167.00 € | ||
| 100mg | 234.00 € | ||
| 200mg | 350.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BI-78D3
CAS:883065-90-5
BI-78D3, a competitive JNK inhibitor. IC50 of BI-78D3 is 280 nM that displays >100 fold …
Formula:
C13H9N5O5S2
Purity:
100% - 97.89%
Color and Shape:
Solid
Molecular weight:
379.37
Ref: TM-T6784
| 2mg | 38.00 € | ||
| 5mg | 55.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 163.00 € | ||
| 50mg | 253.00 € | ||
| 100mg | 401.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ARS-1620
CAS:1698055-85-4
ARS-1620 is a covalent inhibitor of K-RASG12C.
Formula:
C21H17ClF2N4O2
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
430.84
Ref: TM-T7609
| 1mg | 90.00 € | ||
| 2mg | 115.00 € | ||
| 5mg | 185.00 € | ||
| 10mg | 269.00 € | ||
| 25mg | 531.00 € | ||
| 50mg | 763.00 € | ||
| 100mg | 916.00 € | ||
| 1mL*10mM (DMSO) | 211.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tizaterkib
CAS:2097416-76-5
Tizaterkib (AZD-0364) is a potent and selective ERK2 inhibitor.
Formula:
C24H24F2N8O2
Purity:
99.24% - 99.6%
Color and Shape:
Solid
Molecular weight:
494.5
Ref: TM-T10429
| 1mg | 93.00 € | ||
| 2mg | 135.00 € | ||
| 5mg | 216.00 € | ||
| 10mg | 365.00 € | ||
| 25mg | 615.00 € | ||
| 50mg | 876.00 € | ||
| 1mL*10mM (DMSO) | 229.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Rubrofusarin gentiobioside
CAS:24577-90-0
Rubrofusarin gentiobioside (Rubrofusarin-6-O-beta-D-gentiobioside) decreases the expression of TGF-beta1 and fibronectin and NF-kappaB DNA binding activity.
Formula:
C27H32O15
Purity:
99.75% - 99.91%
Color and Shape:
Solid
Molecular weight:
596.53
Ref: TM-TN2165
| 1mg | 53.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 278.00 € | ||
| 50mg | 403.00 € | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ro 5126766
CAS:946128-88-7
RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM, 19 nM, 56 …
Formula:
C21H18FN5O5S
Purity:
98.13% - 98.3%
Color and Shape:
Solid
Molecular weight:
471.46
Ref: TM-T6971
| 1mg | 57.00 € | ||
| 2mg | 81.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 324.00 € | ||
| 50mg | 515.00 € | ||
| 100mg | 744.00 € | ||
| 1mL*10mM (DMSO) | 118.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CK1-IN-1
CAS:1784751-20-7
CK1-IN-1, a CK1 inhibitor with IC50: 15nM CK1δ, 16nM CK1ε, 73nM p38σ; patent WO2015119579A1.
Formula:
C24H15F2N3
Purity:
98.79%
Color and Shape:
Solid
Molecular weight:
383.39
Ref: TM-T5393
| 1mg | 50.00 € | ||
| 2mg | 65.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 159.00 € | ||
| 25mg | 304.00 € | ||
| 50mg | 468.00 € | ||
| 100mg | 703.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
DB07268
CAS:929007-72-7
DB07268 is a potent and selective JNK1 inhibitor.
Formula:
C17H15N5O2
Purity:
98.2% - 98.91%
Color and Shape:
Solid
Molecular weight:
321.33
Ref: TM-T3200
| 2mg | 51.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 121.00 € | ||
| 25mg | 232.00 € | ||
| 50mg | 418.00 € | ||
| 100mg | 618.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
magnolin
CAS:31008-18-1
Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo …
Formula:
C23H28O7
Purity:
98% - 99.57%
Color and Shape:
Solid
Molecular weight:
416.46
Ref: TM-T3857
| 20mg | 90.00 € | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
LJI308
CAS:1627709-94-7
LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 …
Formula:
C21H18F2N2O2
Purity:
98.86% - 99.73%
Color and Shape:
Solid
Molecular weight:
368.38
Ref: TM-T6878
| 1mg | 45.00 € | ||
| 2mg | 36.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 211.00 € | ||
| 50mg | 330.00 € | ||
| 100mg | 507.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
2-Aminooctadecane-1,3,4-Triol
CAS:13552-11-9
2-Aminooctadecane-1,3,4-Triol (Phytosphingosine) is a natural product.
Formula:
C18H39NO3
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
317.51
Ref: TM-TN6814
| 1mg | 185.00 € | ||
| 5mg | 415.00 € | ||
| 10mg | 613.00 € | ||
| 25mg | 937.00 € | ||
| 50mg | 1,309.00 € | ||
| 100mg | 1,764.00 € | ||
| 200mg | 1,367.00 € | ||
| 500mg | 3,455.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Nardosinone
CAS:23720-80-1
Nardosinone inhibits H9c2 cell hypertrophy, protects neurons from OGD, and boosts neurite outgrowth by modifying …
Formula:
C15H22O3
Purity:
98.82% - 99%
Color and Shape:
Solid
Molecular weight:
250.33
Ref: TM-T6S1740
| 2mg | 36.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 129.00 € | ||
| 50mg | 202.00 € | ||
| 100mg | 296.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
methyl 5-(3,4-dimethoxyphenyl)isoxazole-3-carboxylate
CAS:517870-17-6
methyl 5-(3,4-dimethoxyphenyl)isoxazole-3-carboxylate is a biochemical.
Formula:
C13H13NO5
Purity:
97.69%
Color and Shape:
Solid
Molecular weight:
263.25
Ref: TM-T8911
| 5mg | 35.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 82.00 € | ||
| 50mg | 109.00 € | ||
| 100mg | 163.00 € | ||
| 200mg | 237.00 € | ||
| 1mL*10mM (DMSO) | 44.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
RAF709
CAS:1628838-42-5
RAF709 is a novel Raf kinase inhibitor with IC50s of 0.5 and 1.8 nM for …
Formula:
C28H29F3N4O4
Purity:
99.43% - 99.83%
Color and Shape:
Solid
Molecular weight:
542.55
Ref: TM-T3711
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 130.00 € | ||
| 25mg | 256.00 € | ||
| 50mg | 419.00 € | ||
| 100mg | 618.00 € | ||
| 500mg | 1,287.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ASK1-IN-1
CAS:2411382-24-4
ASK1-IN-1 inhibits apoptosis kinase 1, crucial in cell stress responses, with 21 nM IC50.
Formula:
C19H19N9O2
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
405.41
Ref: TM-T9697
| 1mg | 90.00 € | ||
| 5mg | 212.00 € | ||
| 10mg | 317.00 € | ||
| 25mg | 574.00 € | ||
| 50mg | 862.00 € | ||
| 100mg | 1,201.00 € | ||
| 1mL*10mM (DMSO) | 234.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
