MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
Found 885 products of "MAPK"
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DB07268
CAS:<p>DB07268 is a potent and selective JNK1 inhibitor.</p>Formula:C17H15N5O2Purity:98.2% - 98.91%Color and Shape:SolidMolecular weight:321.33p-Cresyl sulfate potassium
CAS:<p>p-Cresyl sulfate potassium (p-Tolyl sulfate potassium salt) is a prototype protein-bound uremic toxin derived from the metabolites of tyrosine and phenylalanine</p>Formula:C7H7KO4SPurity:99.38%Color and Shape:SolidMolecular weight:226.29XMD17-109
CAS:<p>XMD17-109 (ERK5-IN-1) is a new selective ERK-5 inhibitor (EC50: 4.2 uM, HEK293 cells).</p>Formula:C36H46N8O3Purity:98.75% - 99.7%Color and Shape:SolidMolecular weight:638.8Rasarfin
CAS:<p>Rasarfin inhibits Ras and ARF6.</p>Formula:C23H24ClN3O3Purity:97.98%Color and Shape:SolidMolecular weight:425.91GS87
CAS:<p>GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive differentiation of AML cells.</p>Formula:C16H11N5O2SPurity:98.86%Color and Shape:SolidMolecular weight:337.36SB-590885
CAS:<p>SB590885 is an effective B-Raf inhibitor (Ki: 0.16 nM, in a cell-free assay).</p>Formula:C27H27N5O2Purity:95.42% - 99.06%Color and Shape:SolidMolecular weight:453.54JNK-IN-7
CAS:<p>JNK-IN-7 (JNK inhibitor) is a selective JNK1/2/3 inhibitor (IC50: 1.54/1.99/0.75 nM).</p>Formula:C28H27N7O2Purity:98.02% - 99.53%Color and Shape:SolidMolecular weight:493.56ZT-12-037-01
CAS:<p>Zt-12-037-01 is a ATP competitive STK19 inhibitor（IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).</p>Formula:C21H31N5O2Purity:99.56%Color and Shape:SolidMolecular weight:385.5Theaflavin 3,3′-digallate
CAS:<p>Theaflavin 3,3'-digallate, a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer</p>Formula:C43H32O20Purity:98.71% - 99.86%Color and Shape:SolidMolecular weight:868.7KRPEP-2D acetate
<p>KRPEP-2D acetate: inhibitor targeting K-Ras(G12D) mutant, a crucial cancer-related protein.</p>Formula:C110H186N44O27S2Purity:98.94%Color and Shape:SolidMolecular weight:2621.06SGX-523
CAS:<p>SGX-523 is a selective Met inhibitor (IC50: 4 nM), no inhibitory to Abl, BRAFV599E, p38α, and c-Raf.</p>Formula:C18H13N7SPurity:99% - >99.99%Color and Shape:SolidMolecular weight:359.41R1487
CAS:<p>R1487 is an orally bioavailable and highly selective p38α mitogen-activated protein kinase inhibitor.</p>Formula:C19H18F2N4O3Purity:99.77%Color and Shape:SolidMolecular weight:388.37GNE-495
CAS:<p>GNE-495 is a potent and specific MAP4K4 inhibitor (IC50: 3.7 nM).</p>Formula:C22H20FN5O2Purity:99.22% - 99.57%Color and Shape:SolidMolecular weight:405.42ARS-1620
CAS:<p>ARS-1620 is a covalent inhibitor of K-RASG12C.</p>Formula:C21H17ClF2N4O2Purity:98.86%Color and Shape:SolidMolecular weight:430.84Neflamapimod
CAS:<p>Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.</p>Formula:C19H9Cl2F2N3OSPurity:97.88% - 99.75%Color and Shape:SolidMolecular weight:436.26Belvarafenib TFA
<p>Belvarafenib TFA (HM95573 TFA) inhibits RAF: B-RAF (56 nM), B-RAFv600E (7 nM), C-RAF (5 nM) effectively.</p>Formula:C25H17ClF4N6O3SColor and Shape:SolidMolecular weight:592.95K-Ras-IN-1
CAS:<p>K-Ras-IN-1 is a K-Ras inhibitor.</p>Formula:C11H13NOSPurity:98.72%Color and Shape:SolidMolecular weight:207.29BMS582949
CAS:<p>BMS-582949 inhibits p38 MAPK with 13 nM IC50, blocking kinase activity and activation.</p>Formula:C22H26N6O2Purity:98.11%Color and Shape:SolidMolecular weight:406.48TA-01
CAS:<p>TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.</p>Formula:C20H12F3N3Purity:99.55% - 99.94%Color and Shape:SolidMolecular weight:351.32JNK-IN-8
CAS:<p>JNK-IN-8 (JNK Inhibitor XVI) is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM).</p>Formula:C29H29N7O2Purity:99.24% - >99.99%Color and Shape:SolidMolecular weight:507.59
