MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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ERK1/2 inhibitor 9
CAS:2169302-75-2
ERK1/2 Inhibitor 9 (Probe 1), a covalent antagonist of ERK1/2, exhibits sub-micromolar efficacy in cellular …
Formula:
C31H32ClN7O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
586.08
Ref: TM-T78190
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Feb 2025
BI-0474
CAS:2750570-55-7
BI-0474: KRASG12C inhibitor, IC50=7.0 nM, blocks GDP-KRAS/SOS1, anti-tumor in NCI-H358 cells & lung cancer model, …
Formula:
C30H37N9O2S
Purity:
100%
Color and Shape:
Solid
Molecular weight:
587.74
Ref: TM-T69529
| 1mg | 360.00 € | ||
| 5mg | 759.00 € | ||
| 10mg | 1,141.00 € | ||
| 25mg | 1,846.00 € | ||
| 50mg | 2,545.00 € | ||
| 1mL*10mM (DMSO) | 728.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
KRAS G12C inhibitor 13
CAS:2241719-75-3
KRAS G12C inhibitor 13 is a KRAS G12C inhibitor .
Formula:
C40H46F3N7O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
745.83
Ref: TM-T11767
| 25mg | 1,967.00 € | ||
| 50mg | 2,600.00 € | ||
| 100mg | 3,460.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
KRas G12C inhibitor 1
CAS:2158297-28-8
KRas G12C inhibitor 1 is a compound that inhibits KRas G12C.
Formula:
C31H38N6O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
542.67
Ref: TM-T11776
| 25mg | 1,549.00 € | ||
| 50mg | 2,031.00 € | ||
| 100mg | 2,609.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
MS934
CAS:2756323-15-4
MS934, a novel VHL-recruiting MEK 1/2 degrader, exhibits potent anti-proliferative effects on HT-29 cell growth, …
Formula:
C52H69F3IN7O6S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1104.11
Ref: TM-T79143
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Feb 2025
PROTAC KRAS G12C degrader-3
CAS:2768099-51-8
PROTAC KRAS G12C Degrader-3 (Comp 283) serves as a potent degrader of KRAS G12C, utilized …
Formula:
C63H75ClN14O6
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1159.81
Ref: TM-T79148
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Feb 2025
pan-KRAS-IN-3
CAS:2875116-29-1
Pan-KRAS-IN-3 (Example 84) is a pan-KRAS inhibitor suitable for cancer research [1].
Formula:
C33H32F3N5O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
587.63
Ref: TM-T79814
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Feb 2025
XRP44X
CAS:729605-21-4
XRP44X (XRP 44X) is a potent inhibitor of Ras-Net (Elk-3) pathway.
Formula:
C21H21ClN4O
Purity:
97.51%
Color and Shape:
Solid
Molecular weight:
380.87
Ref: TM-T20759
| 10mg | 54.00 € | ||
| 25mg | 79.00 € | ||
| 50mg | 109.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
KRAS G12C inhibitor 17
CAS:2349393-04-8
KRAS G12C inhibitor 17 is a potent KRAS G12C inhibitor.
Formula:
C24H20ClF2N3O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
471.88
Ref: TM-T11771
| 25mg | 1,827.00 € | ||
| 50mg | 2,404.00 € | ||
| 100mg | 3,168.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
KRAS G12C inhibitor 59
CAS:2914919-88-1
KRAS G12C Inhibitor 59 is a compound with anticancer properties.
Formula:
C32H39F6N7O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
715.69
Ref: TM-T79150
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Feb 2025
RMC-4998
CAS:2642037-07-6
RMC-4998 is a molecular glue compound exhibiting potent antitumor activity, capable of forming a ternary …
Formula:
C57H74N8O7
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
983.25
Ref: TM-T79870
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Feb 2025
Nedometinib
CAS:2252314-46-6
Nedometinib (NFX-179) is a MEK1 inhibitor with anticancer and antitumor activities, which can be used …
Formula:
C17H16FIN4O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
470.24
Ref: TM-T78209
| 1mg | 72.00 € | ||
| 5mg | 153.00 € | ||
| 10mg | 217.00 € | ||
| 25mg | 357.00 € | ||
| 50mg | 607.00 € | ||
| 100mg | 991.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
KRAS G12D modulator-1
CAS:2883034-05-5
KRAS G12D modulator-1 (compound 6), a potent modulator of KRAS G12D, exhibits IC50 values ranging …
Formula:
C30H36FN5O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
549.64
Ref: TM-T79072
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Feb 2025
Glycinexylidide
CAS:18865-38-8
Glycinexylidide (GX), the active metabolite of the local anesthetic Lidocaine, exhibits properties significant in inhibiting …
Formula:
C10H14N2O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
178.23
Ref: TM-T80638
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Feb 2025
p38 MAPK-IN-1
CAS:1006378-90-0
p38 MAPK-IN-1: selective p38 MAPK inhibitor, IC50 68 nM, good bioavailability, sustained, low clearance.
Formula:
C21H14F2N2O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
348.35
Ref: TM-T16424
| 2mg | 186.00 € | ||
| 5mg | 325.00 € | ||
| 25mg | 1,058.00 € | ||
| 50mg | 1,385.00 € | ||
| 100mg | 1,884.00 € | ||
| 1mL*10mM (DMSO) | 361.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
KRAS G12C inhibitor 16
CAS:2349392-79-4
KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor.
Formula:
C24H21ClFN3O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
453.89
Ref: TM-T11770
| 1mg | 426.00 € | ||
| 2mg | 624.00 € | ||
| 5mg | 988.00 € | ||
| 10mg | 1,323.00 € | ||
| 25mg | 1,967.00 € | ||
| 50mg | 2,600.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
pan-KRAS-IN-4
CAS:2885961-55-5
Pan-KRAS-IN-4 (compound 5) is a potent KRAS inhibitor, demonstrating IC50 values of 0.37 nM for …
Formula:
C36H34F2N6O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
636.69
Ref: TM-T79799
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Feb 2025
KRAS G12C inhibitor 58
CAS:2915599-52-7
KRAS G12C inhibitor 58 is utilized in cancer research as an inhibitor of the KRAS …
Formula:
C51H64ClF4N9O8S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1074.62
Ref: TM-T79057
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Feb 2025
TH-Z827
CAS:2847881-81-4
TH-Z827 is a mutant-selective inhibitor targeting KRAS(G12D) with an IC50 of 2.4 μM, demonstrating specificity …
Formula:
C30H38N6O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
498.66
Ref: TM-T79092
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Feb 2025
KRAS G12C inhibitor 5
CAS:2158297-63-1
KRAS G12C inhibitor 5 is a KRas G12C inhibitor.
Formula:
C32H37N7O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
551.68
Ref: TM-T11780
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
