MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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DOR agonist 2
CAS:1212540-02-7
Compound 3 (DOR agonist 2) acts as a Delta Opioid Receptor agonist. It inhibits the …
Formula:
C29H26N2O3
Color and Shape:
Liquid
Molecular weight:
450.53
Ref: TM-T200382
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 24 Apr 2025
KU004
CAS:1260401-93-1
KU004, a potent dual EGFR/HER2 inhibitor, exhibits anticancer properties. It inhibits the proliferation of human …
Formula:
C29H27ClFN4O2P
Color and Shape:
Liquid
Molecular weight:
548.98
Ref: TM-T89998
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 24 Apr 2025
INS018 055
CAS:2828567-39-9
INS018 055 (TNIK&MAP4K4-IN-2) is a TNIK and MAP4K4 inhibitor with anti-fibrotic activity.
Formula:
C27H30FN7O
Color and Shape:
Liquid
Molecular weight:
487.57
Ref: TM-T87545
| 1mg | 109.00 € | ||
| 5mg | 258.00 € | ||
| 10mg | 385.00 € | ||
| 25mg | 633.00 € | ||
| 50mg | 869.00 € |
Estimated delivery in United States, on Thursday 24 Apr 2025
KRAS inhibitor-35
CAS:3030078-96-4
KRAS inhibitor-35 (compound 72) is a KRAS inhibitor with an IC50 of 2 nM, utilized …
Formula:
C38H32F4N6O3S
Color and Shape:
Liquid
Molecular weight:
728.76
Ref: TM-T200557
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 24 Apr 2025
KRAS inhibitor-34
CAS:3054800-66-4
KRAS inhibitor-34 (compound 27) is a KRAS inhibitor with an IC50 of 6.4 nM and …
Formula:
C43H41F3N6O3
Color and Shape:
Liquid
Molecular weight:
746.82
Ref: TM-T200670
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 24 Apr 2025
PF-03715455
CAS:1056164-52-3
PF-03715455 is a potent p38 MAPK inhibitor, reducing TNFα in blood (IC50=1.7 nM) with selectivity …
Formula:
C35H34ClN7O3S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
700.27
Ref: TM-T16477
| 5mg | 4,654.00 € |
Estimated delivery in United States, on Thursday 24 Apr 2025
WQ-C-401
CAS:2376694-72-1
WQ-C-401 is an orally active inhibitor of the platelet-derived growth factor receptor (PDGFR). It inhibits …
Formula:
C24H26N4O3
Color and Shape:
Liquid
Molecular weight:
418.49
Ref: TM-T200766
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 24 Apr 2025
Claturafenib
CAS:2754408-94-9
Claturafenib (PF-07799933) is a pan-mutant BRAF inhibitor. In HT29 cells, it suppresses pERK with an …
Formula:
C18H15Cl2F2N5O3S
Molecular weight:
490.31
Ref: TM-T201081
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 24 Apr 2025
RGT-018
CAS:2794934-49-7
RGT-018 is a potent oral SOS1 inhibitor with antitumor properties. It exerts its anticancer activity …
Formula:
C27H24F3N7O2
Color and Shape:
Liquid
Molecular weight:
535.52
Ref: TM-T89897
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 24 Apr 2025
IHMT-RAF-128
CAS:2479289-15-9
IHMT-RAF-128 is a potent pan-RAF inhibitor that demonstrates robust antitumor activity in xenograft mouse tumor …
Formula:
C27H24F3N5O2
Color and Shape:
Liquid
Molecular weight:
507.51
Ref: TM-T89984
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 24 Apr 2025
JNK-1-IN-4
CAS:3047795-60-5
JNK-1-IN-4 (Compound E1) is an inhibitor of JNK, targeting JNK-1, JNK-2, and JNK-3 with IC50 …
Formula:
C22H25BrN6O3
Color and Shape:
Liquid
Molecular weight:
501.38
Ref: TM-T200667
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 24 Apr 2025
AM-001
CAS:340817-81-4
AM-001 is a non-competitive inhibitor of Epac1, preventing the activation of its downstream effector Rap1 …
Formula:
C24H16FN3OS2
Molecular weight:
445.53
Ref: TM-T201281
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 24 Apr 2025
KRAS inhibitor-37
CAS:3058573-95-5
KRAS inhibitor-37 (compound 2) is a potent inhibitor of KRAS, exhibiting low dissociation constants (KD) …
Formula:
C32H33ClFN7O3
Molecular weight:
618.1
Ref: TM-T201259
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 24 Apr 2025
BMS-214662
CAS:195987-41-8
BMS-214662: potent, selective farnesyl transferase inhibitor; triggers apoptosis in CML stem cells; antitumor effects.
Formula:
C25H23N5O2S2
Color and Shape:
Solid
Molecular weight:
489.61
Ref: TM-T10567
| 25mg | 2,106.00 € | ||
| 50mg | 2,789.00 € | ||
| 100mg | 3,744.00 € |
Estimated delivery in United States, on Thursday 24 Apr 2025
KRas G12C inhibitor 2
CAS:2206735-61-5
KRas G12C inhibitor 2 is a compound that inhibits KRas G12C.
Formula:
C32H37N7O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
567.68
Ref: TM-T11777
| 25mg | 2,377.00 € | ||
| 50mg | 3,152.00 € | ||
| 100mg | 4,289.00 € |
Estimated delivery in United States, on Thursday 24 Apr 2025
ERK-IN-2
CAS:2743576-56-7
ERK-IN-2, an ERK2 inhibitor, exhibits an IC50 value of 1.8 nM. At doses greater than …
Formula:
C16H18ClN5O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
347.8
Ref: TM-T11225
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Thursday 24 Apr 2025
PS-166276
CAS:348089-57-6
PS-166276 is a potent p38 inhibitor with low cytotoxicity. It exhibits an IC50 value of …
Formula:
C20H30N8O
Molecular weight:
398.51
Ref: TM-T201008
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 24 Apr 2025
Luvometinib
CAS:2739690-43-6
Luvometinib is an inhibitor of the mitogen-activated protein kinase (MEK) with antitumor activity.
Formula:
C26H22F2IN5O4S
Molecular weight:
665.45
Ref: TM-T201266
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 24 Apr 2025
Rineterkib
CAS:1715025-32-3
Rineterkib (ERK-IN-1) is an inhibitor of RAF and ERK1/2 activating mutations in the MAPK pathway.
Formula:
C26H27BrF3N5O2
Purity:
98.4%
Color and Shape:
Solid
Molecular weight:
578.42
Ref: TM-T11224
| 1mg | 96.00 € | ||
| 5mg | 190.00 € | ||
| 10mg | 357.00 € | ||
| 25mg | 604.00 € | ||
| 50mg | 860.00 € | ||
| 100mg | 1,170.00 € | ||
| 1mL*10mM (DMSO) | 252.00 € |
Estimated delivery in United States, on Thursday 8 May 2025
Garsorasib
CAS:2559761-14-5
Garsorasib is an effective KRAS G12C inhibitor (IC50 = 10 nM) and can be used …
Formula:
C32H32F2N8O2
Purity:
98.99%
Color and Shape:
Solid
Molecular weight:
598.65
Ref: TM-T40186
| 1mg | Discontinued | Request information | |
| 2mg | Discontinued | Request information | |
| 5mg | Discontinued | Request information | |
| 10mg | Discontinued | Request information | |
| 25mg | Discontinued | Request information | |
| 50mg | Discontinued | Request information | |
| 100mg | Discontinued | Request information | |
| 1ml*10 (DMSO) | Discontinued | Request information | |
| 1mL*10mM (DMSO) | Discontinued | Request information |
