MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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DOR agonist 2
CAS:1212540-02-7
Compound 3 (DOR agonist 2) acts as a Delta Opioid Receptor agonist. It inhibits the …
Formula:
C29H26N2O3
Color and Shape:
Solid
Molecular weight:
450.53
Ref: TM-T200382
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 8 Aug 2025
SJ-C1044
CAS:2121503-76-0
SJ-C1044 is an orally effective pan-RAF inhibitor demonstrating immunomodulatory and antitumor activities. It targets wild-type …
Formula:
C25H14F7N7O
Color and Shape:
Solid
Molecular weight:
561.41
Ref: TM-T200357
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 8 Aug 2025
LSN3074753
CAS:1455031-68-1
LSN3074753, a derivative of LY3009120, acts as a pan-RAF and Raf dimer inhibitor. This compound …
Formula:
C24H30FN5O2
Color and Shape:
Solid
Molecular weight:
439.53
Ref: TM-T89906
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 8 Aug 2025
EBI-1051
CAS:1801896-05-8
EBI-1051 is a highly potent and orally efficacious inhibitor of MEK (IC50: 3.9 nM).
Formula:
C18H15F2IN2O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
504.22
Ref: TM-T15193
| 25mg | 1,928.00 € | ||
| 50mg | 2,670.00 € | ||
| 100mg | 3,353.00 € |
Estimated delivery in United States, on Friday 8 Aug 2025
Luvometinib
CAS:2739690-43-6
Luvometinib is an inhibitor of the mitogen-activated protein kinase (MEK) with antitumor activity.
Formula:
C26H22F2IN5O4S
Color and Shape:
Solid
Molecular weight:
665.45
Ref: TM-T201266
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 8 Aug 2025
Brimarafenib
CAS:1643326-82-2
Brimarafenib is a selective RAF dimerization inhibitor, which can inhibit BRAF and CRAF, and exhibits …
Formula:
C24H17F3N4O4
Color and Shape:
Liquid
Molecular weight:
482.41
Ref: TM-T89116
| 1mg | 180.00 € | ||
| 5mg | 398.00 € | ||
| 10mg | 597.00 € | ||
| 25mg | 1,014.00 € | ||
| 50mg | 1,520.00 € |
Estimated delivery in United States, on Friday 8 Aug 2025
KRAS inhibitor-37
CAS:3058573-95-5
KRAS inhibitor-37 (compound 2) is a potent inhibitor of KRAS, exhibiting low dissociation constants (KD) …
Formula:
C32H33ClFN7O3
Color and Shape:
Solid
Molecular weight:
618.10
Ref: TM-T201259
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 8 Aug 2025
RGT-018
CAS:2794934-49-7
RGT-018 is a potent oral SOS1 inhibitor with antitumor properties. It exerts its anticancer activity …
Formula:
C27H24F3N7O2
Color and Shape:
Solid
Molecular weight:
535.52
Ref: TM-T89897
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 8 Aug 2025
INS018 055
CAS:2828567-39-9
INS018 055 (TNIK&MAP4K4-IN-2) is a TNIK and MAP4K4 inhibitor with anti-fibrotic activity.
Formula:
C27H30FN7O
Purity:
98.53%
Color and Shape:
Solid
Molecular weight:
487.57
Ref: TM-T87545
| 1mg | 74.00 € | ||
| 5mg | 160.00 € | ||
| 10mg | 250.00 € | ||
| 25mg | 401.00 € | ||
| 1mL*10mM (DMSO) | 280.00 € |
Estimated delivery in United States, on Friday 8 Aug 2025
PS-166276
CAS:348089-57-6
PS-166276 is a potent p38 inhibitor with low cytotoxicity. It exhibits an IC50 value of …
Formula:
C20H30N8O
Color and Shape:
Solid
Molecular weight:
398.51
Ref: TM-T201008
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 8 Aug 2025
KU004
CAS:1260401-93-1
KU004, a potent dual EGFR/HER2 inhibitor, exhibits anticancer properties. It inhibits the proliferation of human …
Formula:
C29H27ClFN4O2P
Color and Shape:
Solid
Molecular weight:
548.98
Ref: TM-T89998
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 8 Aug 2025
Rineterkib
CAS:1715025-32-3
Rineterkib (ERK-IN-1) is an inhibitor of RAF and ERK1/2 activating mutations in the MAPK pathway.
Formula:
C26H27BrF3N5O2
Purity:
98.4%
Color and Shape:
Solid
Molecular weight:
578.42
Ref: TM-T11224
| 1mg | 95.00 € | ||
| 5mg | 188.00 € | ||
| 10mg | 354.00 € | ||
| 25mg | 597.00 € | ||
| 50mg | 852.00 € | ||
| 100mg | 1,159.00 € | ||
| 1mL*10mM (DMSO) | 249.00 € |
Estimated delivery in United States, on Friday 22 Aug 2025
Garsorasib
CAS:2559761-14-5
Garsorasib is an effective KRAS G12C inhibitor (IC50 = 10 nM) and can be used …
Formula:
C32H32F2N8O2
Purity:
98.99%
Color and Shape:
Solid
Molecular weight:
598.65
Ref: TM-T40186
| 1mg | Discontinued | Request information | |
| 2mg | Discontinued | Request information | |
| 10mg | Discontinued | Request information | |
| 50mg | Discontinued | Request information | |
| 100mg | Discontinued | Request information | |
| 1mL*10mM (DMSO) | Discontinued | Request information |
