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MAPK

MAPK

MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.

Found 881 products of "MAPK"

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  • AZD6703 free base
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    AZD6703 free base

    CAS:
    <p>AZD6703 is a potent, selective and reversible orally bioavailable inhibitor of p38 mitogen-activated protein kinase 14 (MAPK14).</p>
    Formula:C24H27N5O2
    Color and Shape:Solid
    Molecular weight:417.5

    Ref: TM-T26721

  • Kobe2601
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    Kobe2601

    CAS:
    <p>Kobe2601 is a Kobe0065 and Kobe02602 water-soluble analog. It displays inhibitory activity towards Ras-Raf binding.</p>
    Formula:C13H10FN5O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:351.31

    Ref: TM-T24267

  • GSK329
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    GSK329

    CAS:
    <p>GSK329 selectively inhibits TNNI3K, showing cardioprotection in ischemic heart models.</p>
    Formula:C19H14Cl2F3N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:472.25

    Ref: TM-T24109

  • GSK649A
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    GSK649A

    CAS:
    <p>GSK649A is a novel activator of Satellite Cell Proliferation, it could enhance repair of Damaged Muscle.</p>
    Formula:C15H12ClFN6OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:378.81

    Ref: TM-T27486

  • CP-281384
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    CP-281384

    CAS:
    <p>CP-281384 is a potent, p38alpha-selective inhibitor.</p>
    Formula:C18H14F2N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:340.33

    Ref: TM-T27062

  • RBC6
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    RBC6

    CAS:
    <p>RBC6 is an inhibitor of the binding of Ral to its effector RALBP1.</p>
    Formula:C16H14Cl2N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:365.21

    Ref: TM-T24707

  • CP-944629
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    CP-944629

    CAS:
    <p>CP-944629 is a novel, potent, and selective inhibitor of p38alpha.</p>
    Formula:C19H15F3N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:372.34

    Ref: TM-T27067

  • BNC-1
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    BNC-1

    CAS:
    <p>BNC-1 reduces amyloid in mice, enhances synapses by activating Elk-1.</p>
    Formula:C16H14N2O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:282.29

    Ref: TM-T26879

  • (2Z,3Z)-U0126
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    (2Z,3Z)-U0126

    CAS:
    U0126 selectively inhibits MEK1/2, blocks MAPK/ERK signaling, and suppresses Ki-ras-induced cell growth, with IC50s of 72 nM and 58 nM for MEK1/2.
    Formula:C18H16N6S2
    Color and Shape:Solid
    Molecular weight:380.49

    Ref: TM-T69826

  • Migoprotafib
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    Migoprotafib

    CAS:
    Migoprotafib (GDC-1971) is a potent and highly selective SHP2 (Src Homology-2 Domain-Containing Phosphatase 2) inhibitor for advanced solid tumours.
    Formula:C25H26N8O
    Color and Shape:Solid
    Molecular weight:454.53

    Ref: TM-T62798

  • BSJ-04-122
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    BSJ-04-122

    CAS:
    <p>BSJ-04-122: MKK4/7 inhibitor with IC50s of 4 nM &amp; 181 nM, used in cancer research.</p>
    Formula:C15H12ClN5O
    Purity:97.61%
    Color and Shape:Solid
    Molecular weight:313.74

    Ref: TM-T73182

  • CK1-IN-2
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    CK1-IN-2

    CAS:
    <p>CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor p38a, and is used in DUX4 overexpression-associated diseases, such as muscular dystrophy.</p>
    Formula:C17H12FN3O2
    Purity:99.31%
    Color and Shape:Solid
    Molecular weight:309.29

    Ref: TM-T79145

  • SR-3306
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    SR-3306

    CAS:
    <p>SR-3306 is a brain-penetrant and selective pan-JNK (JNK1/2/3) inhibitor with IC50 values ​​of 67 nM, 283 nM, 159 nM.Cost-effective and quality-assured.</p>
    Formula:C28H26N8O
    Purity:99.38% - 99.71%
    Color and Shape:Solid
    Molecular weight:490.56

    Ref: TM-T16927

  • GNE-1858
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    GNE-1858

    CAS:
    <p>GNE-1858 inhibits HPK1; IC50: 1.9 nM for wild-type, 1.9 nM (HPK1-TSEE), 4.5 nM (HPK1-SA).</p>
    Formula:C21H26F2N8
    Purity:99.36%
    Color and Shape:Solid
    Molecular weight:428.48

    Ref: TM-T11438

  • J30-8
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    J30-8

    CAS:
    <p>J30-8 is a JNK3 inhibitor (IC50: 40 nM) with neuroprotective activity and can be used to study neurodegenerative diseases such as Alzheimer's disease.</p>
    Formula:C17H9ClFN3O2S
    Purity:99.90%
    Color and Shape:Solid
    Molecular weight:373.79

    Ref: TM-T11702

  • TAK1/MAP4K2 inhibitor 1
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    TAK1/MAP4K2 inhibitor 1

    CAS:
    <p>TAK1/MAP4K2 inhibitor 1 (compound 5) is a dual kinase inhibitor of TAK1 and MAP4K2 with IC50 values of 41.1 nM and 18.2 nM, respectively.</p>
    Formula:C29H31F3N6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:552.59

    Ref: TM-T10444

  • RMM-46
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    RMM-46

    CAS:
    <p>RMM-46 is a reversible covalent inhibitor with high ligand efficiency and selectivity for MSK/RSK family kinases.</p>
    Formula:C24H26N4O5
    Purity:98.89%
    Color and Shape:Solid
    Molecular weight:450.49

    Ref: TM-T26103

  • LY-2584702 hydrochloride
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    LY-2584702 hydrochloride

    CAS:
    <p>Ly-2584702 hydrochloride is a p70S6K selective ATP competitive inhibitor with IC50 of 4 nM.In the S6K1 enzyme assay, the IC50 of LY-2584702 was 2 nM.</p>
    Formula:C21H20ClF4N7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:481.88

    Ref: TM-T11900

  • MEK inhibitor
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    MEK inhibitor

    CAS:
    <p>MEK inhibitor is a MEK receptor and cell cycle protein/CDK complex inhibitor with antitumor activity that can be used to study tumor cell proliferation.</p>
    Formula:C26H26N4O2
    Purity:97.48%
    Color and Shape:Solid
    Molecular weight:426.51

    Ref: TM-T11993

  • NSC-70220
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    NSC-70220

    CAS:
    <p>SOS1-IN-1 is an inhibitor of SOS1.</p>
    Formula:C22H15NO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:325.36

    Ref: TM-T12978