MAPK

MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.

Found 881 products of "MAPK"

Purity (%)

100

products per page.

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CXJ-2
CAS:
- 2919976-92-2
CXJ-2, a cyclic peptide, binds EDPs, inhibits PI3K/ERK, and reduces hepatic cell growth/migration, offering antifibrotic effects.
Formula:C₅₅H₈₇N₁₅O₂₂
Purity:98%
Color and Shape:Solid
Molecular weight:1310.37
Ref: TM-T74782
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HPK1-IN-13
CAS:
- 2734168-30-8
HPK1-IN-13 is a potent inhibitor of HPK1. HPK1-IN-12 has potential for the study of HPK1-related diseases.
Formula:C₂₅H₂₄FN₅O₂
Color and Shape:Solid
Molecular weight:445.49
Ref: TM-T62629
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KRAS G12C inhibitor 59
CAS:
- 2914919-88-1
KRAS G12C Inhibitor 59 is a compound with anticancer properties.
Formula:C₃₂H₃₉F₆N₇O₅
Purity:98%
Color and Shape:Solid
Molecular weight:715.69
Ref: TM-T79150
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(R)-VX-11e
CAS:
- 1680187-43-2
(R)-VX-11e is an isomer of VX-11e, a potent and selective ERK2 inhibitor with potential to inhibit tumor growth.
Formula:C₂₄H₂₀Cl₂FN₅O₂
Purity:98.73%
Color and Shape:Solid
Molecular weight:500.35
Ref: TM-T78143
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JNK3 inhibitor-1
CAS:
- 2622877-97-6
JNK3 inhibitor-1: potent, selective, IC50 of 0.005 μM, orally bioavailable, brain-penetrant.
Formula:C₂₁H₁₇ClFN₅O₂S
Color and Shape:Solid
Molecular weight:457.91
Ref: TM-T40248
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GGTI-297
CAS:
- 181045-83-0
GGTI-297 is a potent, cell-permeable, and selective peptidomimetic inhibitor of GGTase I compared to Farnesyl Transferase (FTase).
Formula:C₂₆H₃₁N₃O₃S
Color and Shape:Solid
Molecular weight:465.61
Ref: TM-T70157
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DT-061
CAS:
- 1809427-19-7
DT-061 is an orally bioavailable protein phosphatase 2A (PP2A) activator. It could be applied in the therapy of KRAS-mutant and MYC-driven tumorigenesis.
Formula:C₂₅H₂₃F₃N₂O₅S
Purity:98%
Color and Shape:Solid
Molecular weight:520.52
Ref: TM-T10060L
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KRAS G12C inhibitor 16
CAS:
- 2349392-79-4
KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor.
Formula:C₂₄H₂₁ClFN₃O₃
Purity:97.84%
Color and Shape:Solid
Molecular weight:453.89
Ref: TM-T11770
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MS934
CAS:
- 2756323-15-4
MS934, a novel VHL-recruiting MEK 1/2 degrader, exhibits potent anti-proliferative effects on HT-29 cell growth, achieving a GI50 of 0.023 μM.
Formula:C₅₂H₆₉F₃IN₇O₆S
Purity:98%
Color and Shape:Solid
Molecular weight:1104.11
Ref: TM-T79143
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KRAS G12C inhibitor 58
CAS:
- 2915599-52-7
KRAS G12C inhibitor 58 is utilized in cancer research as an inhibitor of the KRAS G12C mutation [1].
Formula:C₅₁H₆₄ClF₄N₉O₈S
Purity:98%
Color and Shape:Solid
Molecular weight:1074.62
Ref: TM-T79057
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Ilaprazole sodium hydrate
CAS:
- 2322264-11-7
Ilaprazole sodium hydrate (IY-81149 sodium hydrate) is a proton pump inhibitor that blocks the transport of HSV particles.
Formula:C₁₉H₂₁N₄NaO₄S
Purity:99.2%
Color and Shape:Solid
Molecular weight:424.45
Ref: TM-T78218
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KRAS G12D mutation regulator 4
CAS:
- 2621927-57-7
KRAS G12D mutation regulator 4 can be used in studies about Ras.
Formula:C₃₃H₃₃FN₆O₂
Color and Shape:Solid
Molecular weight:564.65
Ref: TM-T77804
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KRAS G12D modulator-1
CAS:
- 2883034-05-5
KRAS G12D modulator-1 (compound 6), a potent modulator of KRAS G12D, exhibits IC50 values ranging from 1-10 μM against NEA-G12D, PPI-G12D, and p ERK-AGS, and is
Formula:C₃₀H₃₆FN₅O₄
Purity:98%
Color and Shape:Solid
Molecular weight:549.64
Ref: TM-T79072
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ERK1/2 inhibitor 5
CAS:
- 2560552-75-0
ERK1/2 inhibitor 5: potent against ERK1/2, may combat cancer and inflammation.
Formula:C₂₈H₃₂ClFN₆O₅
Color and Shape:Solid
Molecular weight:587.04
Ref: TM-T64155
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XRP44X
CAS:
- 729605-21-4
XRP44X (XRP 44X) is a potent inhibitor of Ras-Net (Elk-3) pathway.
Formula:C₂₁H₂₁ClN₄O
Purity:99.67%
Color and Shape:Solid
Molecular weight:380.87
Ref: TM-T20759
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pan-KRAS-IN-2
CAS:
- 2882825-14-9
Pan-KRAS-IN-2 (compound 6) is a broad-spectrum KRAS inhibitor exhibiting potent activity with IC50 values of ≤10 nM against KRAS wild type and its mutants (G12D
Formula:C₃₄H₃₄F₂N₄O₃
Purity:98%
Color and Shape:Solid
Molecular weight:584.66
Ref: TM-T79800
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SB-682330A
CAS:
- 502498-66-0
SB-682330A is a Raf kinase inhibitor.
Formula:C₂₈H₂₇N₃O₃
Color and Shape:Solid
Molecular weight:453.53
Ref: TM-T62781
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KRAS G12C inhibitor 17
CAS:
- 2349393-04-8
KRAS G12C inhibitor 17 is a potent KRAS G12C inhibitor.
Formula:C₂₄H₂₀ClF₂N₃O₃
Purity:98%
Color and Shape:Solid
Molecular weight:471.88
Ref: TM-T11771
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TC13172
CAS:
- 2093393-05-4
TC13172 is a potent, covalent MLKL inhibitor, selective over RIPK1/RIPK3. It blocks TSZ-induced necroptosis (EC50=2nM) and MLKL oligomerization at 100nM.
Formula:C₁₇H₁₆N₄O₅S
Purity:98%
Color and Shape:Solid
Molecular weight:388.4
Ref: TM-T17010
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KRAS inhibitor FB9
CAS:
- 2042365-57-9
KRAS inhibitor FB9 can be used in studies about Ras.
Formula:C₂₃H₂₁ClF₄N₂O₅
Color and Shape:Solid
Molecular weight:516.87
Ref: TM-T77806

MAPK

Found 881 products of "MAPK"

CXJ-2

Ref: TM-T74782

HPK1-IN-13

Ref: TM-T62629

KRAS G12C inhibitor 59

Ref: TM-T79150

(R)-VX-11e

Ref: TM-T78143

JNK3 inhibitor-1

Ref: TM-T40248

GGTI-297

Ref: TM-T70157

DT-061

Ref: TM-T10060L

KRAS G12C inhibitor 16

Ref: TM-T11770

MS934

Ref: TM-T79143

KRAS G12C inhibitor 58

Ref: TM-T79057

Ilaprazole sodium hydrate

Ref: TM-T78218

KRAS G12D mutation regulator 4

Ref: TM-T77804

KRAS G12D modulator-1

Ref: TM-T79072

ERK1/2 inhibitor 5

Ref: TM-T64155

XRP44X

Ref: TM-T20759

pan-KRAS-IN-2

Ref: TM-T79800

SB-682330A

Ref: TM-T62781

KRAS G12C inhibitor 17

Ref: TM-T11771

TC13172

Ref: TM-T17010

KRAS inhibitor FB9

Ref: TM-T77806