MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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K-Ras G12C-IN-4
CAS:2376328-55-9
K-Ras G12C-IN-4 is a potent co-valent Inhibitor of KRAS G12C..
Formula:
C31H33ClN4O4
Purity:
99.00%
Color and Shape:
Solid
Molecular weight:
561.07
Ref: TM-T11738
| 1mg | 72.00 € | ||
| 5mg | 164.00 € | ||
| 10mg | 241.00 € | ||
| 25mg | 410.00 € | ||
| 50mg | 543.00 € | ||
| 100mg | 797.00 € | ||
| 200mg | 1,072.00 € | ||
| 1mL*10mM (DMSO) | 196.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
AX-15836
CAS:2035509-96-5
AX-15836 is an inhibitor of ERK5 (IC50 : 8 nM).
Formula:
C32H40N8O5S
Purity:
98.96%
Color and Shape:
Solid
Molecular weight:
648.78
Ref: TM-T14360
| 1mg | 57.00 € | ||
| 2mg | 81.00 € | ||
| 5mg | 120.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 295.00 € | ||
| 50mg | 421.00 € | ||
| 100mg | 593.00 € | ||
| 500mg | 1,216.00 € | ||
| 1mL*10mM (DMSO) | 172.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
HI-TOPK-032
CAS:487020-03-1
HI-TOPK-032 is an effective and specific inhibitor of TOPK.
Formula:
C20H11N5OS
Purity:
98.52%
Color and Shape:
Solid
Molecular weight:
369.4
Ref: TM-T15481
| 2mg | 46.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 320.00 € | ||
| 100mg | 550.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
Honokiol
CAS:35354-74-6
Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt …
Formula:
C18H18O2
Purity:
99.65% - 99.87%
Color and Shape:
Dark Brown To White Fine Powder With Pleasant Odor Spicy And Slightly Bitter Taste
Molecular weight:
266.33
Ref: TM-T3001
| 50mg | 54.00 € | ||
| 100mg | 68.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
PF-3644022
CAS:1276121-88-0
PF-3644022 is a selective MK2 inhibitor, effective against TNFα (IC50: 5.2 nM, Ki: 3 nM), …
Formula:
C21H18N4OS
Purity:
98.13%
Color and Shape:
Solid
Molecular weight:
374.46
Ref: TM-T16501
| 1mg | 37.00 € | ||
| 5mg | 110.00 € | ||
| 10mg | 199.00 € | ||
| 25mg | 410.00 € | ||
| 50mg | 604.00 € | ||
| 100mg | 809.00 € | ||
| 500mg | 1,635.00 € | ||
| 1mL*10mM (DMSO) | 182.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
Regorafénib N-oxyde (M2)
CAS:835621-11-9
Regorafénib N-oxyde M2 is an active metabolite of Regorafenib.
Formula:
C21H15ClF4N4O4
Purity:
98.03% - 99.48%
Color and Shape:
Solid
Molecular weight:
498.81
Ref: TM-T10157
| 1mg | 44.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 318.00 € | ||
| 100mg | 461.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
Cristacarpin
CAS:74515-47-2
Cristacarpin targets DNA repair-deficient yeast, induces ER stress and ROS, triggers senescence in pancreatic/breast cancer …
Formula:
C21H22O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
354.402
Ref: TM-TN3719
| 5mg | 1,860.00 € | ||
| 1mL*10mM (DMSO) | 2,150.00 € |
Estimated delivery in United States, on Thursday 13 Feb 2025
MEK/RAF-IN-1
MEK/RAF-IN-1 (Compound 16b) serves as an inhibitor targeting both MEK and RAF, demonstrating potent efficacy …
Formula:
C28H29F3N6O5S
Color and Shape:
Liquid
Molecular weight:
618.63
Ref: TM-T200267
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 13 Feb 2025
n-Butyl α-D-fructofuranoside
CAS:80971-59-1
N-Butyl α-D-fructofuranoside, extracted from the root barks of Ulmus davidiana var.
Formula:
C10H20O6
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
236.26
Ref: TM-T80005
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 13 Feb 2025
Manassantin A
CAS:88497-87-4
Manassantin A: potent HIF-1 inhibitor, guards stomach lining, curbs iNOS/NF-κB, may help treat airway diseases, …
Formula:
C42H52O11
Purity:
98%
Color and Shape:
Solid
Molecular weight:
732.867
Ref: TM-TN4489
| 10mg | 1,208.00 € | ||
| 1mL*10mM (DMSO) | 1,227.00 € |
Estimated delivery in United States, on Thursday 13 Feb 2025
MLKL-IN-2
CAS:899759-16-1
MLKL-IN-2 is an MLKL inhibitor with potential tumorigenic activity for the study of cellular necrosis-related …
Formula:
C26H25N5O
Purity:
98.61%
Color and Shape:
Solid
Molecular weight:
423.51
Ref: TM-T41027
| 1mg | 90.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | 305.00 € | ||
| 25mg | 631.00 € | ||
| 50mg | 993.00 € | ||
| 100mg | 1,532.00 € | ||
| 200mg | 2,070.00 € |
Estimated delivery in United States, on Thursday 13 Feb 2025
Zunsemetinib
CAS:1640282-42-3
Zunsemetinib (ATI-450) is a p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor.
Formula:
C25H22ClF2N5O3
Purity:
99.77%
Color and Shape:
Liquid
Molecular weight:
513.92
Ref: TM-T39126
| 1mg | 268.00 € | ||
| 5mg | 651.00 € | ||
| 10mg | 1,114.00 € | ||
| 25mg | 1,661.00 € | ||
| 50mg | 2,237.00 € | ||
| 100mg | 3,001.00 € |
Estimated delivery in United States, on Thursday 13 Feb 2025
KG5
CAS:877874-85-6
KG5 inhibits PDGFRβ, B-Raf, FLT3, KIT, c-Raf; has anticancer and antiangiogenic effects; Kd: 520 nM …
Formula:
C20H16F3N7OS
Purity:
98.2%
Color and Shape:
Liquid
Molecular weight:
459.45
Ref: TM-T41003
| 1mg | 34.00 € | ||
| 2mg | 45.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 198.00 € | ||
| 50mg | 302.00 € | ||
| 100mg | 434.00 € | ||
| 200mg | 608.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Thursday 13 Feb 2025
Haginin A
CAS:74174-29-1
Haginin A inhibits hyperpigmentation and skin disorders, reduces tyrosinase/TRP-1, and has antioxidant properties.
Formula:
C17H16O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
300.31
Ref: TM-TN4179
| 5mg | 708.00 € | ||
| 1mL*10mM (DMSO) | 727.00 € |
Estimated delivery in United States, on Thursday 13 Feb 2025
Pseudoginsenoside Rh2
CAS:1370264-16-6
Pseudoginsenoside Rh2 has cytotoxicity, it induces mitochondrial apoptosis in A549 cells and is responsible for …
Formula:
C36H62O8
Purity:
98%
Color and Shape:
Solid
Molecular weight:
622.884
Ref: TM-TN2114
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Thursday 13 Feb 2025
7,8-Didehydrocimigenol
CAS:150972-72-8
7,8-Didehydrocimigenol treats cardiovascular issues by upregulating PPAR-γ, inhibiting NF-kB, and reducing VCAM-1 in EC.
Formula:
C30H46O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
486.693
Ref: TM-TN3219
| 5mg | 518.00 € | ||
| 1mL*10mM (DMSO) | 537.00 € |
Estimated delivery in United States, on Thursday 13 Feb 2025
Talmapimod hydrochloride
CAS:309915-12-6
Talmapimod hydrochloride: selective p38α inhibitor, 9 nM IC50, 10x less effective on p38β, >2000-fold selective …
Formula:
C27H31Cl2FN4O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
549.46
Ref: TM-T12871L
| 25mg | 1,432.00 € |
Estimated delivery in United States, on Thursday 13 Feb 2025
Antimicrobial agent-21
CAS:724746-07-0
Antimicrobial agent-21 is a potent mitogen activated protein kinase inhibitor with antibacterial, anti-inflammatory and antitumor …
Formula:
C18H13N3OS
Purity:
99.72%
Color and Shape:
Liquid
Molecular weight:
319.38
Ref: TM-T67942
| 1mg | 85.00 € | ||
| 5mg | 177.00 € | ||
| 10mg | 270.00 € | ||
| 25mg | 436.00 € | ||
| 50mg | 587.00 € | ||
| 100mg | 803.00 € | ||
| 200mg | 1,080.00 € | ||
| 1mL*10mM (DMSO) | 284.00 € |
Estimated delivery in United States, on Thursday 13 Feb 2025
Lyoniresinol
CAS:14464-90-5
Lyoniresinol, a lignan from Tarenna attenuata, has antioxidant and anti-melanogenic properties, with an IC50 of …
Formula:
C22H28O8
Purity:
98%
Color and Shape:
Solid
Molecular weight:
420.45
Ref: TM-TN4469
| 5mg | To inquire |
Estimated delivery in United States, on Thursday 13 Feb 2025
AMG-548 hydrochloride (864249-60-5 free base)
AMG-548 hydrochloride is an orally active and selective p38α inhibitor (Ki: 0.5 nM) and shows …
Formula:
C29H28ClN5O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
498.02
Ref: TM-T10298
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Thursday 13 Feb 2025
