ERK
ERK is a key protein in the MAPK (Mitogen-Activated Protein Kinase) signaling pathway, which is involved in transmitting signals from cell surface receptors to the DNA in the cell nucleus. ERK plays a crucial role in the regulation of various cellular processes, including proliferation, differentiation, and survival. Dysregulation of ERK signaling is associated with the development of cancer and other diseases, making it an important target for therapeutic intervention. At CymitQuimica, we offer a selection of high-quality ERK inhibitors and modulators to support your research in cell signaling, oncology, and therapeutic development.
Found 217 products of "ERK"
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EPHB2 Protein, Cynomolgus, Recombinant (His)
EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression.Color and Shape:Lyophilized PowderMolecular weight:59.09 kDa (predicted). Due to glycosylation, the protein migrates to 65-75 kDa based on Tris-Bis PAGE result.EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) is expressed in Baculovirus insect cells with His and GST tag.Color and Shape:Lyophilized PowderMolecular weight:75.2 kDa (predicted); 65 kDa (reducing conditions)Pamoic acid disodium
CAS:Pamoic acid disodium is a GPR35 agonist.Formula:C23H16NaO6Purity:99.73%Color and Shape:Yellow PowderMolecular weight:411.36EphB2 Protein, Human, Recombinant (His & hFc)
EphB2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag.Color and Shape:Lyophilized PowderMolecular weight:86 kDa (predicted); 90-100 kDa (reducing condition, due to glycosylation)ERK2 Protein, Human, Recombinant (GST)
ERK2 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.Color and Shape:Lyophilized PowderMolecular weight:67 kDa (predicted); 67 kDa (reducing conditions)EphB2 Protein, Mouse, Recombinant (His)
EphB2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:59.3 kDa (predicted); 65 kDa (reducing conditions)ERK2 Protein, Mouse, Recombinant (His & GST)
ERK2 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.Color and Shape:Lyophilized PowderMolecular weight:69.1 kDa (predicted); 60 kDa (reducing conditions)EphB2 Protein, Human, Recombinant (His)
EphB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:59.2 kDa (predicted); 65-75 kDa (reducing condition, due to glycosylation)PERK-IN-2
CAS:PERK-IN-2 is a potent inhibitor of PERK(IC50 of 0.2 nM).Formula:C23H18F3N5OPurity:98%Color and Shape:SolidMolecular weight:437.42ERα degrader-2
CAS:ERα degrader-2 is an estrogen receptor (SERD) degrader with anticancer activity that inhibits ERα for the prevention and treatment of HER-positive breast cancFormula:C29H27F3N2O2Purity:99.71%Color and Shape:SolidMolecular weight:492.53TRPM4 inhibitor 8
CAS:TRPM4 inhibitor 8 is an inhibitor of Transient receptor potential melastatin 4(TRPM4) which contributes to viability, migration, cell cycle shift, and adhesion.Formula:C11H17BrN2Purity:99.84%Color and Shape:SolidMolecular weight:257.17Ref: TM-T9776
5mg44.00€1mL*10mM (DMSO)48.00€10mg62.00€25mg90.00€50mg170.00€100mg268.00€200mg403.00€500mg660.00€EphB2 Protein, Mouse, Recombinant (hFc)
EphB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Color and Shape:Lyophilized PowderMolecular weight:84.6 kDa (predicted); 96.6 kDa (reducing conditions)GPR34 receptor antagonist 3
Compound 5e, a GPR34 receptor antagonist, exhibits selective inhibition of lysophosphatidylserine-induced ERK1/2 phosphorylation in a dose-dependent manner,Color and Shape:Odour SolidSBI-810 hydrochloride
CAS:SBI-810 hydrochloride is a β-arrestin-2 (βarr2)-biased allosteric modulator of NTSR1 (neurotensin receptor 1), exerting analgesic effects.Formula:C27H35ClN4O2Purity:99.42%Color and Shape:SolidMolecular weight:483.05EM127
CAS:EM127: covalent SMYD3 inhibitor, KD 13μM, impedes ERK1/2, hinders SMYD3 gene regulation, long-term methyltransferase reduction, potential in cancer study.Formula:C14H18ClN3O3Purity:97.55%Color and Shape:SolidMolecular weight:311.76(E/Z)-BIX 02189
CAS:(E/Z)-BIX 02189 is a selective inhibitor of MEK5 with IC50 of 1.5 nM.Formula:C27H28N4O2Purity:98% - 99.89%Color and Shape:SolidMolecular weight:440.54Ref: TM-T2416
1mg38.00€5mg82.00€1mL*10mM (DMSO)92.00€10mg116.00€25mg210.00€50mg358.00€100mg550.00€200mg780.00€SC99
CAS:SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Formula:C15H8Cl2FN3OPurity:99.56%Color and Shape:SolidMolecular weight:336.15Ref: TM-T8719
1mg43.00€5mg87.00€1mL*10mM (DMSO)94.00€10mg133.00€25mg227.00€50mg344.00€100mg429.00€200mg597.00€Longdaysin
CAS:Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).Formula:C16H16F3N5Purity:99.97%Color and Shape:SolidMolecular weight:335.33N-tert-butyl-α-Phenylnitrone
CAS:N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity.Formula:C11H15NOPurity:99.46% - 99.84%Color and Shape:SolidMolecular weight:177.24Corynoxeine
CAS:Corynoxeine inhibits ERK1/2, curbs VSMC growth induced by PDGF-BB, and may prevent vascular diseases and restenosis post-angioplasty.Formula:C22H26N2O4Purity:98.61% - 99.94%Color and Shape:SolidMolecular weight:382.45
