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ERK

ERK

ERK is a key protein in the MAPK (Mitogen-Activated Protein Kinase) signaling pathway, which is involved in transmitting signals from cell surface receptors to the DNA in the cell nucleus. ERK plays a crucial role in the regulation of various cellular processes, including proliferation, differentiation, and survival. Dysregulation of ERK signaling is associated with the development of cancer and other diseases, making it an important target for therapeutic intervention. At CymitQuimica, we offer a selection of high-quality ERK inhibitors and modulators to support your research in cell signaling, oncology, and therapeutic development.

Found 193 products of "ERK"

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  • Edaxeterkib

    CAS:
    <p>Edaxeterkib is a potent extracellular signal- regulated kinase (ERK) inhibitor for the research of cancer.</p>
    Formula:C26H27N7O2
    Color and Shape:Solid
    Molecular weight:469.549
  • PD 198306

    CAS:
    <p>PD 198306: a MEK inhibitor with antihyperalgesic properties, reduces Streptozocin-boosted active ERK1.</p>
    Formula:C18H16F3IN2O2
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:476.23
  • ROCK-IN-5

    CAS:
    <p>ROCK-IN-5 (I-B-37) inhibits kinases like ROCK/ERK/GSK; may aid in cardiac and neuro disease studies.</p>
    Formula:C16H11ClFN3OS
    Purity:99.72% - 99.83%
    Color and Shape:Solid
    Molecular weight:347.79
  • MAPK Inhibitor Library


    <p>A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;</p>
    Color and Shape:Odour Solid
  • Kinase Inhibitor Library


    <p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>
    Color and Shape:Odour Solid
  • A-674563 HCl (552325-73-2(free base))

    CAS:
    <p>A-674563: Oral Akt inhibitor (Ki: 11 nM for Akt1), also targets PKA/Cdk2, with 10-1800x selectivity over other kinases.</p>
    Formula:C22H23ClN4O
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:394.9
  • Fulipiftide

    CAS:
    <p>Fulipiftide is a short peptide derived from pigment epithelium-derived factor (PEDF). It stimulates the amplification of nuclear stem cell factor+TSPC by activating the ERK2 and STAT3 signaling pathways. Fulipiftide also exhibits anti-inflammatory properties and is applicable in research on acute tendon injuries.</p>
    Formula:C144H227N41O47
    Color and Shape:Solid
    Molecular weight:3284.59
  • CHPG hydrochloride


    <p>CHPG hydrochloride is a selective agonist of mGluR5.</p>
    Formula:C8H9Cl2NO3
    Purity:98.1%
    Color and Shape:Soild
    Molecular weight:238.07
  • PPM-3


    <p>PPM-3, a selective PROTAC ERK5 degrader, exhibits a potent inhibitory concentration (IC 50) of 62.4 nM.</p>
    Formula:C54H69N11O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1000.26
  • EphB2 Protein, Mouse, Recombinant (hFc)


    <p>EphB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:84.6 kDa (predicted); 96.6 kDa (reducing conditions)
  • ERK2 Protein, Human, Recombinant (GST)


    <p>ERK2 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:67 kDa (predicted); 67 kDa (reducing conditions)
  • EphB2 Protein, Human, Recombinant (His)


    <p>EphB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:59.2 kDa (predicted); 65-75 kDa (reducing condition, due to glycosylation)
  • EphB2 Protein, Mouse, Recombinant (His)


    <p>EphB2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:59.3 kDa (predicted); 65 kDa (reducing conditions)
  • PERK-IN-2

    CAS:
    <p>PERK-IN-2 is a potent inhibitor of PERK(IC50 of 0.2 nM).</p>
    Formula:C23H18F3N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:437.42
  • ERα degrader-2

    CAS:
    <p>ERα degrader-2 is an estrogen receptor (SERD) degrader with anticancer activity that inhibits ERα for the prevention and treatment of HER-positive breast canc</p>
    Formula:C29H27F3N2O2
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:492.53
  • TRPM4 inhibitor 8

    CAS:
    <p>TRPM4 inhibitor 8 is an inhibitor of Transient receptor potential melastatin 4(TRPM4) which contributes to viability, migration, cell cycle shift, and adhesion.</p>
    Formula:C11H17BrN2
    Purity:97%
    Color and Shape:Solid
    Molecular weight:257.17
  • EphB2 Protein, Human, Recombinant (His & hFc)


    <p>EphB2 Protein, Human, Recombinant (His &amp; hFc) is expressed in HEK293 mammalian cells with His and hFc tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:86 kDa (predicted); 90-100 kDa (reducing condition, due to glycosylation)
  • Pamoic acid disodium

    CAS:
    <p>Pamoic acid disodium is a GPR35 agonist.</p>
    Formula:C23H16NaO6
    Purity:99.73%
    Color and Shape:Yellow Powder
    Molecular weight:411.36
  • EM127

    CAS:
    <p>EM127: covalent SMYD3 inhibitor, KD 13μM, impedes ERK1/2, hinders SMYD3 gene regulation, long-term methyltransferase reduction, potential in cancer study.</p>
    Formula:C14H18ClN3O3
    Purity:97.61%
    Color and Shape:Solid
    Molecular weight:311.76
  • ERK2 Protein, Mouse, Recombinant (His & GST)


    <p>ERK2 Protein, Mouse, Recombinant (His &amp; GST) is expressed in Baculovirus insect cells with His and GST tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:69.1 kDa (predicted); 60 kDa (reducing conditions)