ERK
ERK is a key protein in the MAPK (Mitogen-Activated Protein Kinase) signaling pathway, which is involved in transmitting signals from cell surface receptors to the DNA in the cell nucleus. ERK plays a crucial role in the regulation of various cellular processes, including proliferation, differentiation, and survival. Dysregulation of ERK signaling is associated with the development of cancer and other diseases, making it an important target for therapeutic intervention. At CymitQuimica, we offer a selection of high-quality ERK inhibitors and modulators to support your research in cell signaling, oncology, and therapeutic development.
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PD98059
CAS:167869-21-8
PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.
Formula:
C16H13NO3
Purity:
100% - 99.66%
Color and Shape:
Yellow Solid
Molecular weight:
267.28
Ref: TM-T2623
| 5mg | 40.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 82.00 € | ||
| 50mg | 106.00 € | ||
| 100mg | 177.00 € | ||
| 200mg | 264.00 € | ||
| 500mg | 444.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Piperlongumine
CAS:20069-09-4
Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.
Formula:
C17H19NO5
Purity:
97.03% - 99.89%
Color and Shape:
Solid
Molecular weight:
317.34
Ref: TM-T6947
| 10mg | 35.00 € | ||
| 25mg | 55.00 € | ||
| 50mg | 88.00 € | ||
| 100mg | 119.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Isomerazin
CAS:1088-17-1
Isomerazin (Isomeranzin) has anti-inflammatory activity, it suppresses inflammation by inhibiting M1 macrophage polarization through the …
Formula:
C15H16O4
Purity:
99.8%
Color and Shape:
Solid
Molecular weight:
260.29
Ref: TM-TN1786
| 1mg | 97.00 € | ||
| 5mg | 250.00 € | ||
| 10mg | 369.00 € | ||
| 25mg | 607.00 € | ||
| 50mg | 853.00 € | ||
| 1mL*10mM (DMSO) | 226.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
FR 180204
CAS:865362-74-9
FR 180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.
Formula:
C18H13N7
Purity:
98% - 99.49%
Color and Shape:
Solid
Molecular weight:
327.34
Ref: TM-T1956
| 1mg | 43.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 138.00 € | ||
| 25mg | 221.00 € | ||
| 50mg | 331.00 € | ||
| 100mg | 497.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Decursinol angelate
CAS:130848-06-5
Decursinol angelate is anti-tumor, anti-inflammatory, anti-oxidant, hepatoprotective, and inhibits VEGF and cancer cell invasion.
Formula:
C19H20O5
Purity:
99.93%
Color and Shape:
Solid
Molecular weight:
328.36
Ref: TM-TN1557
| 5mg | 50.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 146.00 € | ||
| 50mg | 212.00 € | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Meranzin hydrate
CAS:5875-49-0
Meranzin hydrate acts as an antidepressant and aids digestion, targeting α2-adrenoceptors and AMPA receptors, hastened …
Formula:
C15H18O5
Purity:
99.49%
Color and Shape:
Solid
Molecular weight:
278.3
Ref: TM-TN1922
| 1mg | 87.00 € | ||
| 5mg | 216.00 € | ||
| 10mg | 324.00 € | ||
| 25mg | 543.00 € | ||
| 50mg | 772.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
TBHQ
CAS:1948-33-0
TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor …
Formula:
C10H14O2
Purity:
99.17% - 99.53%
Color and Shape:
White Solid Powder
Molecular weight:
166.22
Ref: TM-T5364
| 1g | 52.00 € | ||
| 500mg | 48.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
VX-11e
CAS:896720-20-0
VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; …
Formula:
C24H20Cl2FN5O2
Purity:
98.92% - ≥98%
Color and Shape:
Solid
Molecular weight:
500.35
Ref: TM-T3166
| 2mg | 55.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 226.00 € | ||
| 50mg | 359.00 € | ||
| 100mg | 555.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Tetrahydrocoptisine
CAS:4312-32-7
Tetrahydrocoptisine (Stylopine) quells inflammation, protects against ALI, guards the gut, and blocks key pro-inflammatory pathways.
Formula:
C19H17NO4
Purity:
99.71% - ≥95%
Color and Shape:
Solid
Molecular weight:
323.34
Ref: TM-T4S2063
| 1mg | 52.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 153.00 € | ||
| 25mg | 249.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 545.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
SCH772984
CAS:942183-80-4
SCH772984 is an ERK inhibitor and is highly selective and ATP-competitive. SCH772984 exhibits antitumor activity. …
Formula:
C33H33N9O2
Purity:
97.65% - 98.75%
Color and Shape:
Solid
Molecular weight:
587.67
Ref: TM-T6066
| 1mg | 52.00 € | ||
| 2mg | 77.00 € | ||
| 5mg | 99.00 € | ||
| 10mg | 148.00 € | ||
| 25mg | 291.00 € | ||
| 50mg | 437.00 € | ||
| 100mg | 642.00 € | ||
| 200mg | 914.00 € | ||
| 500mg | 1,359.00 € | ||
| 1mL*10mM (DMSO) | 131.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Theliatinib
CAS:1353644-70-8
Theliatinib: potent, selective EGFR inhibitor, anti-tumor; Ki=0.05 nM (EGFR), IC50=3 nM (EGFR), 22 nM (T790M/L858R).
Formula:
C25H26N6O2
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
442.51
Ref: TM-T7322
| 1mg | 52.00 € | ||
| 5mg | 144.00 € | ||
| 10mg | 227.00 € | ||
| 25mg | 376.00 € | ||
| 50mg | 567.00 € | ||
| 100mg | 775.00 € | ||
| 1mL*10mM (DMSO) | 159.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Gypenoside L
CAS:94987-09-4
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through …
Formula:
C42H72O14
Purity:
99.42% - 99.65%
Color and Shape:
Solid
Molecular weight:
801.01
Ref: TM-TN1721
| 1mg | 126.00 € | ||
| 5mg | 296.00 € | ||
| 10mg | 378.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Periplocin
CAS:13137-64-9
Periplocin fights lung cancer, induces apoptosis, stunts growth via beta-catenin/Tcf, and treats rheumatoid arthritis/traditional ailments.
Formula:
C36H56O13
Purity:
99.37% - 99.66%
Color and Shape:
Solid
Molecular weight:
696.82
Ref: TM-T5S1982
| 1mg | 35.00 € | ||
| 5mg | 77.00 € | ||
| 10mg | 106.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 253.00 € | ||
| 100mg | 375.00 € | ||
| 500mg | 892.00 € | ||
| 1mL*10mM (DMSO) | 107.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
SC99
CAS:882290-02-0
SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.
Formula:
C15H8Cl2FN3O
Purity:
99.56%
Color and Shape:
Solid
Molecular weight:
336.15
Ref: TM-T8719
| 1mg | 46.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 140.00 € | ||
| 25mg | 240.00 € | ||
| 50mg | 363.00 € | ||
| 100mg | 452.00 € | ||
| 200mg | 630.00 € | ||
| 1mL*10mM (DMSO) | 99.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Yoda 1
CAS:448947-81-7
Yoda 1 is an agonist of the Piezo1 channel that agonizes human- and mouse-derived Piezo1. …
Formula:
C13H8Cl2N4S2
Purity:
98% - 99.98%
Color and Shape:
Solid
Molecular weight:
355.27
Ref: TM-T7506
| 1mg | 47.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 230.00 € | ||
| 50mg | 447.00 € | ||
| 100mg | 655.00 € | ||
| 500mg | 1,388.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
ERK5-IN-2
CAS:1888305-96-1
ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 μM, 3 …
Formula:
C17H11BrFN3O2
Purity:
99.01%
Color and Shape:
Solid
Molecular weight:
388.19
Ref: TM-T5535
| 1mg | 48.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 283.00 € | ||
| 50mg | 424.00 € | ||
| 100mg | 612.00 € | ||
| 200mg | 842.00 € | ||
| 1mL*10mM (DMSO) | 139.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Asperulosidic acid
CAS:25368-11-0
Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition …
Formula:
C18H24O12
Purity:
99.47%
Color and Shape:
Solid
Molecular weight:
432.38
Ref: TM-TN1410
| 1mg | 154.00 € | ||
| 5mg | 316.00 € | ||
| 10mg | 540.00 € | ||
| 25mg | 852.00 € | ||
| 50mg | 1,121.00 € | ||
| 1mL*10mM (DMSO) | 348.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
CAFESTOL
CAS:469-83-0
Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.
Formula:
C20H28O3
Purity:
97.06% - 99.08%
Color and Shape:
Solid
Molecular weight:
316.43
Ref: TM-T5727
| 2mg | 38.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 159.00 € | ||
| 50mg | 226.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Sulforaphene
CAS:592-95-0
Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for …
Formula:
C6H9NOS2
Purity:
98.01% - 99.19%
Color and Shape:
Slightly Yellowish Liquid
Molecular weight:
175.27
Ref: TM-TL0016
| 1mg | 37.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 227.00 € | ||
| 50mg | 338.00 € | ||
| 100mg | 500.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Acalabrutinib
CAS:1420477-60-6
Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase …
Formula:
C26H23N7O2
Purity:
99.02% - 99.46%
Color and Shape:
Solid
Molecular weight:
465.51
Ref: TM-T3626
| 5mg | 47.00 € | ||
| 10mg | 60.00 € | ||
| 25mg | 82.00 € | ||
| 50mg | 96.00 € | ||
| 100mg | 153.00 € | ||
| 200mg | 227.00 € | ||
| 500mg | 375.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
