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p38 MAPK

p38 MAPK

p38 MAPKs are a subgroup of MAPKs that respond to stress signals and are involved in the regulation of inflammation, cell differentiation, apoptosis, and autophagy. p38 MAPK signaling is crucial in immune responses and is implicated in various diseases, including chronic inflammatory conditions, cancer, and neurodegenerative disorders. At CymitQuimica, we provide a comprehensive range of p38 MAPK inhibitors and modulators to support your research in inflammation, stress response, and therapeutic development.

Found 117 products of "p38 MAPK"

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  • Rotundic acid
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    Rotundic acid

    CAS:
    <p>Rotundic acid fights various cancers: HepG2, A375, NCI-H446, MCF-7, and HT-29.</p>
    Formula:C30H48O5
    Purity:96.91% - 99.97%
    Color and Shape:Solid
    Molecular weight:488.7

    Ref: TM-T5S0506

  • Cornuside
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    Cornuside

    CAS:
    <p>Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.</p>
    Formula:C24H30O14
    Purity:99.86% - >99.99%
    Color and Shape:Solid
    Molecular weight:542.49

    Ref: TM-T4S2326

  • Andrograpanin
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    Andrograpanin

    CAS:
    <p>Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata.</p>
    Formula:C20H30O3
    Purity:99.03% - 99.457%
    Color and Shape:Solid
    Molecular weight:318.45

    Ref: TM-T9218

  • FERULIC ACID METHYL ESTER
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    FERULIC ACID METHYL ESTER

    CAS:
    <p>FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. FERULIC ACID METHYL ESTER has antioxidant activities.</p>
    Formula:C11H12O4
    Purity:99.66% - 99.95%
    Color and Shape:Solid
    Molecular weight:208.21

    Ref: TM-TL0004

  • BMS-582949 hydrochloride
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    BMS-582949 hydrochloride

    CAS:
    <p>The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).</p>
    Formula:C22H27ClN6O2
    Purity:97.57% - 98.75%
    Color and Shape:Solid
    Molecular weight:442.95

    Ref: TM-T3462

  • R1487
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    R1487

    CAS:
    <p>R1487 is an orally bioavailable and highly selective p38α mitogen-activated protein kinase inhibitor.</p>
    Formula:C19H18F2N4O3
    Purity:99.77%
    Color and Shape:Solid
    Molecular weight:388.37

    Ref: TM-T7667

  • SR-318
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    SR-318

    CAS:
    <p>SR-318 inhibits TNF-α (IC50=283 nM), selectively targets p38 MAPK: IC50 of 5nM (p38α), 32nM (p38β), 6.11μM (p38α/β).</p>
    Formula:C27H33N5O2
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:459.58

    Ref: TM-T12997

  • Afatinib Dimaleate
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    Afatinib Dimaleate

    CAS:
    <p>Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.</p>
    Formula:C32H33ClFN5O11
    Purity:98.11% - 99.87%
    Color and Shape:Solid
    Molecular weight:718.08

    Ref: TM-T1773

  • TA-02
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    TA-02

    CAS:
    <p>TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.</p>
    Formula:C20H13F2N3
    Purity:99.35% - 99.79%
    Color and Shape:Solid
    Molecular weight:333.33

    Ref: TM-T4646

  • TA-01
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    TA-01

    CAS:
    <p>TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.</p>
    Formula:C20H12F3N3
    Purity:99.55% - 99.94%
    Color and Shape:Solid
    Molecular weight:351.32

    Ref: TM-T4645

  • Ralimetinib dimesylate
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    Ralimetinib dimesylate

    CAS:
    <p>Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.</p>
    Formula:C24H29FN6·2CH4O3S
    Purity:98% - 99.38%
    Color and Shape:Solid
    Molecular weight:612.74

    Ref: TM-T6047

  • Skepinone-L
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    Skepinone-L

    CAS:
    <p>Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.</p>
    Formula:C24H21F2NO4
    Purity:99.56% - >99.99%
    Color and Shape:Solid
    Molecular weight:425.42

    Ref: TM-T6130

  • SKF-86002
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    SKF-86002

    CAS:
    <p>SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).</p>
    Formula:C16H12FN3S
    Purity:98% - 99.85%
    Color and Shape:Solid
    Molecular weight:297.35

    Ref: TM-T2367

  • SB 242235
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    SB 242235

    CAS:
    <p>SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.</p>
    Formula:C19H20FN5O
    Purity:99.13% - 99.68%
    Color and Shape:Solid
    Molecular weight:353.39

    Ref: TM-T4078

  • Rhoifolin
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    Rhoifolin

    CAS:
    <p>Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.</p>
    Formula:C27H30O14
    Purity:98.11% - 98.58%
    Color and Shape:Solid
    Molecular weight:578.52

    Ref: TM-T2755

  • TAK-715
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    TAK-715

    CAS:
    <p>TAK-715 is a p38 MAPK inhibitor for p38α.</p>
    Formula:C24H21N3OS
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:399.51

    Ref: TM-T6150

  • PD 169316
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    PD 169316

    CAS:
    <p>PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.</p>
    Formula:C20H13FN4O2
    Purity:98.65%
    Color and Shape:Solid
    Molecular weight:360.34

    Ref: TM-T2432

  • AMG-47a
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    AMG-47a

    CAS:
    <p>AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.</p>
    Formula:C29H28F3N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:535.56

    Ref: TM-T7123

  • Acumapimod
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    Acumapimod

    CAS:
    <p>Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 &lt;1 μM).</p>
    Formula:C22H19N5O2
    Purity:≥95%
    Color and Shape:Solid
    Molecular weight:385.42

    Ref: TM-T7367

  • Skatole
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    Skatole

    CAS:
    <p>Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.</p>
    Formula:C9H9N
    Purity:99.74%
    Color and Shape:Leaves From Petroleum Ether; White-Brown Scales Solid
    Molecular weight:131.17

    Ref: TM-T5281