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Potassium Channel

Potassium Channel

Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.

Found 277 products of "Potassium Channel"

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  • VU0134992 hydrochloride
    Targetmol
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    VU0134992 hydrochloride

    CAS:
    VU0134992 hydrochloride is the first subtype-preferring, orally active and selective blocker of Kir4.1 potassium channel pore(IC50 : 0.97 μM).
    Formula:C20H32BrClN2O2
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:447.84

    Ref: TM-T13316

  • Linopirdine
    Targetmol
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    Linopirdine

    CAS:
    <p>Linopirdine (DuP 996) is a TRPV1 agonist.</p>
    Formula:C26H21N3O
    Purity:99.45% - 99.78%
    Color and Shape:Solid
    Molecular weight:391.46

    Ref: TM-T15758

  • IK1 inhibitor PA-6
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    IK1 inhibitor PA-6

    CAS:
    <p>IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouse</p>
    Formula:C31H32N4O2
    Purity:98.9%
    Color and Shape:Solid
    Molecular weight:492.61

    Ref: TM-T15555

  • ML418
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    ML418

    CAS:
    <p>ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.</p>
    Formula:C19H24ClN3O3
    Purity:99.3%
    Color and Shape:Solid
    Molecular weight:377.87

    Ref: TM-T16110

  • Eleclazine hydrochloride
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    Eleclazine hydrochloride

    CAS:
    <p>Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).</p>
    Formula:C21H17ClF3N3O3
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:451.83

    Ref: TM-T15207

  • Dequalinium chloride
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    Dequalinium chloride

    CAS:
    <p>Dequalinium chloride: topical bacteriostat, blocks apamin-sensitive K+ channels, used for wounds, oral infections, potential antifungal, risk of skin ulcers.</p>
    Formula:C30H40Cl2N4
    Purity:99.79% - 99.9%
    Color and Shape:Solid
    Molecular weight:527.59

    Ref: TM-T0979

  • Hydroxyhexamide
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    Hydroxyhexamide

    CAS:
    <p>Hydroxyhexamide ((±)-Hydroxyhexamid) is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agent.</p>
    Formula:C15H22N2O4S
    Purity:98.91%
    Color and Shape:Solid
    Molecular weight:326.41

    Ref: TM-T0150

  • CymitQuimica logo
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    Aekatperone

    <p>Aekatperone, a reversible KATP channel inhibitor, exhibits an IC50 of 9 μM. It is utilized in research related to congenital hyperinsulinism (CHI).</p>
    Formula:C20H25N5O2S
    Color and Shape:Solid
    Molecular weight:399.51

    Ref: TM-T201230

  • Guangxitoxin 1E
    Targetmol
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    Guangxitoxin 1E

    CAS:
    <p>Guangxitoxin 1E acts as a gating modifier since it shifts the voltage-dependence of Kv2.1 K+ currents towards depolarized potentials.</p>
    Formula:C178H248N44O45S7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3948.61

    Ref: TM-TP1531

  • Apamin acetate
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    Apamin acetate

    <p>Apamin acetate: Selective Ca2+-activated K+ channel blocker, 18-amino acid bee venom peptide, promotes synapse repair, anti-inflammatory.</p>
    Purity:96.97%
    Color and Shape:Solid

    Ref: TM-TP1223L

  • CHET3
    Targetmol
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    CHET3

    CAS:
    <p>CHET3 is a highly selective allosteric activator for TASK-3-containing K2P channels. CHET3 has shown potent in vivo analgesic effects. Cost-effective and quality-assured.</p>
    Formula:C21H21N5O3S
    Purity:99.64% - >99.99%
    Color and Shape:Soild
    Molecular weight:423.49

    Ref: TM-T72066

  • Phe-Met-Arg-Phe, amide
    Targetmol
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    Phe-Met-Arg-Phe, amide

    CAS:
    Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.
    Formula:C29H42N8O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:598.76

    Ref: TM-TP1858

  • Potassium Channel Targeted Library
    Targetmol
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    Potassium Channel Targeted Library

    <p>A unique collection of xnum potassium channel blockers and agonists for high throughput and high content screening;</p>
    Color and Shape:Odour Solid

    Ref: TM-L7300

  • MASP-2-IN-1
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    MASP-2-IN-1

    <p>MASP-2-IN-1 (Compound 77) is an inhibitor of mannan-binding lectin-associated serine proteases (MASP), specifically targeting MASP2 and MASP3, with IC50 values of 11.4 nM and 13.2 µM, respectively. It shows weak inhibitory activity on hERG with an IC50 of 175 µM. This compound exhibits poor stability in mouse plasma, with a half-life of 4.4 hours.</p>
    Formula:C22H21N7O3S
    Color and Shape:Solid
    Molecular weight:463.512

    Ref: TM-T204802

  • Ebio2
    Targetmol
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    Ebio2

    <p>Ebio2 is an effective activator of KCNQ2.</p>
    Formula:C17H19F2N3O2
    Color and Shape:Solid
    Molecular weight:335.349

    Ref: TM-T204914

  • BeKm-1
    Targetmol
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    BeKm-1

    CAS:
    <p>Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.</p>
    Formula:C174H261N51O52S6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4091.65

    Ref: TM-TP2072

  • ShK-Dap22
    Targetmol
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    ShK-Dap22

    CAS:
    Potent KV1.3 channel blocker; Kd 23 pM; selective; inhibits T cell activation; IC50 < 500 pM for mKV1.3.
    Formula:C166H268N54O48S7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4012.7

    Ref: TM-TP2123

  • Dalazatide HCl
    Targetmol
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    Dalazatide HCl

    <p>Dalazatide HCl is a peptide and specific Kv1.3 inhibitor that suppresses the activation and proliferation of memory effector T cells,</p>
    Color and Shape:Solid
    Molecular weight:4317.53 (Free base)

    Ref: TM-T76280L1

  • Phe-Met-Arg-Phe amide trifluoroacetate
    Targetmol
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    Phe-Met-Arg-Phe amide trifluoroacetate

    CAS:
    Phe-met-arg-phe amide trifluoroacetate is an activator of K+ current with an ED50 of 23nm on the fundus nerve.
    Formula:C33H44F6N8O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:826.81

    Ref: TM-TP1440

  • RU-TRAAK-2
    Targetmol
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    RU-TRAAK-2

    CAS:
    <p>RU-TRAAK-2 reversibly inhibits TWIK-related K+ channel, inactive on Kv1.2, GIRK2, Slo1.</p>
    Formula:C19H17N3OS
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:335.42

    Ref: TM-T60061