P-gp
P-glycoprotein is an ATP-dependent efflux pump that transports a wide variety of substrates, including drugs, toxins, and lipids, out of cells. It plays a critical role in drug resistance, particularly in cancer, by reducing the intracellular concentration of chemotherapeutic agents. P-gp is also involved in the blood-brain barrier, influencing the central nervous system's exposure to various compounds. At CymitQuimica, we provide a range of P-gp modulators to support your research in drug resistance, pharmacokinetics, and therapeutic development.
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Encequidar
CAS:849675-66-7
Encequidar (HM30181A) is a potent and selective P-glycoprotein inhibitor.
Formula:
C38H36N6O7
Purity:
99.93%
Color and Shape:
Solid
Molecular weight:
688.73
Ref: TM-T8426
| 1mg | 48.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 242.00 € | ||
| 50mg | 373.00 € | ||
| 100mg | 547.00 € | ||
| 1mL*10mM (DMSO) | 133.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Ceefourin 1
CAS:315702-40-0
Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor.
Formula:
C11H10N4S3
Purity:
98.4%
Color and Shape:
Solid
Molecular weight:
294.42
Ref: TM-T8596
| 1mg | 42.00 € | ||
| 2mg | 56.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 247.00 € | ||
| 50mg | 384.00 € | ||
| 100mg | 559.00 € | ||
| 1mL*10mM (DMSO) | 108.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Paris saponin VII
CAS:68124-04-9
Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
Formula:
C51H82O21
Purity:
99.51% - 99.63%
Color and Shape:
Solid
Molecular weight:
1031.18
Ref: TM-T4085
| 1mg | 50.00 € | ||
| 5mg | 106.00 € | ||
| 10mg | 177.00 € | ||
| 25mg | 297.00 € | ||
| 50mg | 443.00 € | ||
| 100mg | 633.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Polyoxyethylene stearate
CAS:9004-99-3
Polyoxyethylene stearate (POES) is an agent of non-ionic emulsifying.
Formula:
C20H40O3
Purity:
n~9-10
Color and Shape:
Light Amber Semisolid
Molecular weight:
328.29775
Ref: TM-T16561
| 5g | 52.00 € | ||
| 10g | 69.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Isosinensetin
CAS:17290-70-9
1. Isosinensetin (6-Demethoxynobiletin) shows antioxidant and HIV-1 protease inhibiting activities.
Formula:
C20H20O7
Purity:
99.05% - ≥95%
Color and Shape:
Solid
Molecular weight:
372.37
Ref: TM-T2S0223
| 1mg | 65.00 € | ||
| 5mg | 140.00 € | ||
| 10mg | 203.00 € | ||
| 25mg | 340.00 € | ||
| 50mg | 501.00 € | ||
| 100mg | 726.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Voacamine
CAS:3371-85-5
Voacamine: an indole alkaloid, CB1 antagonist, inhibits P-gp, may affect rhythm.
Formula:
C43H52N4O5
Purity:
98.54%
Color and Shape:
Solid
Molecular weight:
704.9
Ref: TM-T2S0271
| 1mg | 124.00 € | ||
| 5mg | 259.00 € | ||
| 10mg | 441.00 € | ||
| 25mg | 705.00 € | ||
| 50mg | 932.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Tariquidar
CAS:206873-63-4
Tariquidar (XR9576)(Kd=5.1 nM) is a specific and effective non-competitive inhibitor of P-glycoprotein. It can reverse …
Formula:
C38H38N4O6
Purity:
98.07% - 99.17%
Color and Shape:
Solid
Molecular weight:
646.73
Ref: TM-T6287
| 5mg | 49.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 128.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 373.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Selamectin
CAS:220119-17-5
Selamectin (UK-124114) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and …
Formula:
C43H63NO11
Purity:
99.64%
Color and Shape:
Solid
Molecular weight:
769.96
Ref: TM-T4059
| 5mg | 36.00 € | ||
| 10mg | 54.00 € | ||
| 25mg | 103.00 € | ||
| 50mg | 171.00 € | ||
| 100mg | 266.00 € | ||
| 200mg | 367.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Phellamurin
CAS:52589-11-4
Phellamurin blocks intestinal P-glycoprotein dose-dependently and it seriously interacts with cyclosporin; coadministration should be avoided.
Formula:
C26H30O11
Purity:
93.19%
Color and Shape:
Solid
Molecular weight:
518.51
Ref: TM-TN4761
| 1mg | 162.00 € | ||
| 5mg | 316.00 € | ||
| 10mg | 467.00 € | ||
| 25mg | 744.00 € | ||
| 50mg | 1,060.00 € | ||
| 100mg | 1,426.00 € | ||
| 1mL*10mM (DMSO) | 406.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Sinapine
CAS:18696-26-9
Sinapine: an alkaloid with chemo-resistance, antioxidant, and radioprotective properties from cruciferous seeds.
Formula:
C16H24NO5
Purity:
98% - 99.85%
Color and Shape:
White Or Light-Tan Solid
Molecular weight:
310.37
Ref: TM-T2S1200
| 5mg | 78.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 259.00 € | ||
| 100mg | 371.00 € | ||
| 500mg | 891.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Convallatoxin
CAS:508-75-8
Convallatoxin is a natural product.
Formula:
C29H42O10
Purity:
99.27%
Color and Shape:
Prisms From Methanol + Ether Solid
Molecular weight:
550.64
Ref: TM-TN1525
| 1mg | 132.00 € | ||
| 5mg | 311.00 € | ||
| 10mg | 426.00 € | ||
| 25mg | 699.00 € | ||
| 50mg | 980.00 € | ||
| 1mL*10mM (DMSO) | 375.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Zosuquidar trihydrochloride
CAS:167465-36-3
Zosuquidar trihydrochloride (LY-335979 trihydrochloride) is a potent modulator of P-glycoprotein-mediated multi-drug resistance with Ki of …
Formula:
C32H31F2N3O2·3HCl
Purity:
100% - 99.55%
Color and Shape:
Solid
Molecular weight:
636.99
Ref: TM-T6018
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 244.00 € | ||
| 100mg | 368.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Hypophyllanthin
CAS:33676-00-5
Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
Formula:
C24H30O7
Purity:
98.39%
Color and Shape:
Solid
Molecular weight:
430.49
Ref: TM-TN1757
| 1mg | 52.00 € | ||
| 5mg | 135.00 € | ||
| 10mg | 214.00 € | ||
| 1mL*10mM (DMSO) | 162.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
HM-30181 mesylate monohydrate
CAS:2097125-58-9
HM-30181 mesylate monohydrate is an oral P-glycoprotein (P-gp) inhibitor, used to enhance the oral bioavailability …
Formula:
C39H42N6O11S
Purity:
99.37%
Color and Shape:
Solid
Molecular weight:
802.85
Ref: TM-T9173
| 1mg | 69.00 € | ||
| 2mg | 87.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 194.00 € | ||
| 25mg | 322.00 € | ||
| 50mg | 462.00 € | ||
| 100mg | 671.00 € | ||
| 200mg | 871.00 € | ||
| 500mg | 1,291.00 € | ||
| 1mL*10mM (DMSO) | 185.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Trifluoperazine
CAS:117-89-5
Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.
Formula:
C21H24F3N3S
Purity:
98.3% - 99.03%
Color and Shape:
White To Yellowish Crystalline Powder
Molecular weight:
407.5
Ref: TM-T8389
| 1mg | 48.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 209.00 € | ||
| 50mg | 329.00 € | ||
| 100mg | 495.00 € | ||
| 500mg | 1,114.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
γ-Tocotrienol
CAS:14101-61-2
γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E.
Formula:
C28H42O2
Purity:
97.27% - 98.13%
Color and Shape:
Solid
Molecular weight:
410.63
Ref: TM-T19768
| 1mg | 46.00 € | ||
| 2mg | 61.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 231.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 504.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Sinapine thiocyanate
CAS:7431-77-8
Sinapine Thiocyanate, is a derivative of Sinapine (S486605), an alkaloidal amine found in black mustard …
Formula:
C16H24NO5·CNS
Purity:
98.19% - ≥95%
Color and Shape:
Solid
Molecular weight:
368.45
Ref: TM-T3392
| 10mg | 59.00 € | ||
| 25mg | 87.00 € | ||
| 50mg | 124.00 € | ||
| 100mg | 213.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Solamargine
CAS:20311-51-7
Solamargine, a steroidal alkaloid from Solanum nigrum, inhibits cancer cell growth and induces apoptosis.
Formula:
C45H73NO15
Purity:
99.17% - 99.88%
Color and Shape:
Solid
Molecular weight:
868.06
Ref: TM-T4034
| 1mg | 58.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 339.00 € | ||
| 50mg | 525.00 € | ||
| 100mg | 734.00 € | ||
| 1mL*10mM (DMSO) | 165.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Talinolol
CAS:57460-41-0
(±)-Talinolol is a selective β1 adrenoceptor antagonist well known for its cardioprotective and antihypertensive activity.
Formula:
C20H33N3O3
Purity:
98.80%
Color and Shape:
Solid
Molecular weight:
363.49
Ref: TM-T21640
| 1mg | 73.00 € | ||
| 2mg | 97.00 € | ||
| 5mg | 165.00 € | ||
| 10mg | 296.00 € | ||
| 25mg | 534.00 € | ||
| 50mg | 768.00 € | ||
| 100mg | 1,054.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Elacridar
CAS:143664-11-3
Elacridar (GG918) is a potent inhibitor of P-glycoprotein and BCRP.Cost-effective and quality-assured.
Formula:
C34H33N3O5
Purity:
100% - 99.62%
Color and Shape:
Solid
Molecular weight:
563.64
Ref: TM-T2657
| 5mg | 41.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 106.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 276.00 € | ||
| 200mg | 464.00 € | ||
| 500mg | 736.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
