Sodium Channel
Found 258 products of "Sodium Channel"
6-Benzoylheteratisine
CAS:6-Benzoylheteratisine (Heteratisan-14-one, 6-(benzoyloxy)-20-ethyl-8-hydroxy-1-methoxy-4-meth) is a Aconitum alkaloid.Formula:C29H37NO6Purity:99.87%Color and Shape:SolidMolecular weight:495.61Benzonatate
CAS:Benzonatate is an antagonist of sodium channel protein.Formula:C30H53NO11Purity:99.92%Color and Shape:Colorless To Faintly Yellow Oil LiquidMolecular weight:603.74PF-06869206
CAS:PF-06869206 is an oral selective inhibitor of the sodium-phosphate cotransporter NaPi2a (SLC34A1, IC50: 380 nM).Formula:C15H14ClF3N4O2Purity:99.79% - 99.88%Color and Shape:SolidMolecular weight:374.75Levobupivacaine hydrochloride
CAS:Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.Formula:C18H28N2O·HClPurity:99.74%Color and Shape:White Crystalline PowderMolecular weight:324.893-Deoxyaconitine
CAS:3- Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thusFormula:C34H47NO10Purity:98.31%Color and Shape:SolidMolecular weight:629.74Ralfinamide
CAS:Ralfinamide (Priralfinamide) is an orally available Na-channel blocker for the treatment of neuropathic pain and other pain conditions.Formula:C17H19FN2O2Purity:99.41%Color and Shape:SolidMolecular weight:302.34Propoxycaine hydrochloride
CAS:Propoxycaine hydrochloride is an ester local anesthetic that inhibits voltage-gated sodium channels, modulates nerve impulses, and induces loss of sensation.Formula:C16H27ClN2O3Purity:97.25%Color and Shape:SolidMolecular weight:330.85Riluzole
CAS:Riluzole (RP-54274) is an anticonvulsant, glutamate antagonist, and prolongs ALS patient survival.Formula:C8H5F3N2OSPurity:99.71% - 99.88%Color and Shape:PowderMolecular weight:234.2Benzocaine N-Glucoside (a/b mixture)
CAS:Controlled ProductStability Hygroscopic
Applications The N-Glucoside of Benzocaine (B202970) with anesthetic activity. A potential sun-screening agent.
References Rybczynska, B. et al.: Parfum. Kosm., 48, 125 (1967); Nikolin, A. et al.: Glas. Hemi. Tehnol. Bosne Herceg., 16, 93 (1968);Formula:C15H21NO7Color and Shape:NeatMolecular weight:327.33Oxethazaine
CAS:Controlled ProductApplications A potent local anesthetic that is active even in acidic conditions. It is used (usually in combination with an antacid) for the relief of pain associated with peptic ulcer disease or esophagitis.
References Detrain, M. et al.: Acta. Gastro-Enterol. Belg., 28, 360 (1965); Barbezat, G.O. et al.: Scand. J. Gastroenterol., 13, 321 (1978); Masuda, Y. et al.: Biochem. Pharmacol., 64, 677 (2002);Formula:C28H41N3O3Color and Shape:NeatMolecular weight:467.644’-Hydroxybupivacaine
CAS:Controlled ProductApplications 4’-Hydroxybupivacaine is a metabolite of Bupivacaine. Bupivacaine is an amide-type, long-acting local anesthetic.
References Lindberg, R., et al.: J. Chromatogr. Biomed. Appl., 383, 357 (1986)Formula:C18H28N2O2Color and Shape:NeatMolecular weight:304.42710,11-Dihydro-10-hydroxy Carbamazepine-d4
CAS:10,11-Dihydro-10-hydroxy Carbamazepine-d4 is a deuterated compound of 10,11-Dihydro-10-hydroxy Carbamazepine. 10,11-Dihydro-10-hydroxy Carbamazepine has a CAS number of 29331-92-8. Licarbazepine is the pharmacologically active metabolite of oxcarbazepine, a drug indicated for the treatment of partial seizures and bipolar disorders.Formula:C15H10D4N2O2Color and Shape:SolidMolecular weight:258.31Propafenone-d5 HCl
CAS:Propafenone-d5 HCl is a deuterated compound of Propafenone HCl. Propafenone HCl has a CAS number of 34183-22-7. Propafenone HCl is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias.Formula:C21H23D5ClNO3Molecular weight:382.94N-(Chloroacetyl)-2,5-dimethylaniline
CAS:Controlled ProductApplications N-(Chloroacetyl)-2,5-dimethylaniline is an intermediate in the synthesis of impurities of Lidocaine (L397800), an anesthetic local agent and antiarrythmic class IB agent.
References Groningsson, K., et al.: Anal. Profiles Drug Subs., 14, 207 (1985), Davies, P.S., et al.: Drugs, 64, 937 (2004),Formula:C10H12ClNOColor and Shape:NeatMolecular weight:197.663-(2-Chloropropionyl)amino-4-methyl-2-methoxycarbonylthiophene
CAS:Controlled ProductApplications 3-(2-Chloropropionyl)amino-4-methyl-2-methoxycarbonylthiophene is an intermediate in the synthesis of Articaine-d7 Hydrochloride which is the labelled form of Articaine Hydrochloride (A777905). Articaine Hydrochloride is the Hydrochloride Salt of Articaine (A777900). Articaine is an amide based short-acting local anesthetic use for regional anaesthesia in day-case settings such arthroscopy, hand, food surgery and in dentistry.
References Malamed, S.F., et al.: J. Am. Dent. Assoc., 132, 177 (2001); Luan, F., et al.: Bioorg. Med. Chem., 21, 1870 (2013)Formula:C10H12ClNO3SColor and Shape:NeatMolecular weight:261.732-(3-Bromopropyl)-1,2,4-triazolo-pyridin-3-one
CAS:Controlled ProductApplications Used in the preparation of bicycloamine derivatives as sodium channel inhibitors for treatment of pain, epilepsy and insomnia.
Formula:C9H10BrN3OColor and Shape:NeatMolecular weight:256.1Deacetamide Acetonitrile-pentisomide
CAS:Controlled ProductApplications Deacetamide Acetonitrile-pentisomide is an intermediate in the synthesis of Pentisomide (P275600). Pentisomide is a sodium channel blocker; derivative of disopyramide. Antiarrhythmic (class I).
References Kuhlkamp, V., et al.: Int. J. Cardiol., 36, 69 (1992); Yuan, S., et al.: Cardiovasc. Drug Rev., 11, 74 (1993)Formula:C19H31N3Color and Shape:NeatMolecular weight:301.47Propafenone D7 hydrochloride
CAS:Propafenone D7 hydrochloride is the deuterium labeled Propafenone, and is a classic anti-arrhythmic medication.Formula:C21H28ClNO3Purity:98%Color and Shape:SolidMolecular weight:384.95Methocarbamol D5
CAS:Methocarbamol is a central muscle relaxant. Methocarbamol D5 is deuterium labeled Methocarbamol.Formula:C11H15NO5Purity:98%Color and Shape:SolidMolecular weight:246.27Nav1.8-IN-14
CAS:Nav1.8-IN-14 (compound 20) is an effective selective inhibitor of Nav1.8. It is utilized in the research of pain-associated diseases.Formula:C18H17F5N4O3SColor and Shape:SolidMolecular weight:464.41
