GABA Receptor
GABA receptors are the primary inhibitory neurotransmitter receptors in the central nervous system, playing a critical role in regulating neuronal excitability and maintaining the balance between excitation and inhibition. GABA receptor dysfunction is implicated in various neurological and psychiatric disorders, including epilepsy, anxiety, and depression. At CymitQuimica, we provide a comprehensive range of GABA receptor modulators to support your research in neurobiology, mental health, and therapeutic development.
Found 365 products of "GABA Receptor"
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E2730
CAS:E2730 is a non-competitive GABA transporter 1 (GAT1) inhibitor with anti-epileptic activity, useful in studying neurological disorders.Formula:C9H8F4N2O2SPurity:98.22% - 98.54%Color and Shape:SolidMolecular weight:284.23CGS 20625
CAS:partial agonist for the benzodiazepine binding site of the GABAA receptorFormula:C18H19N3O2Purity:99.61%Color and Shape:SolidMolecular weight:309.36SX-3228
CAS:SX-3228 is a selective agonist of benzodiazepine1 (BZ1) receptor(IC50 of 17 nM).Formula:C18H18N4O3Purity:98%Color and Shape:SolidMolecular weight:338.36Org 20599
CAS:GABAA receptor agonistFormula:C25H40ClNO3Purity:98%Color and Shape:SolidMolecular weight:438.04U-101017
CAS:U-101017 is a partial benzodiazepine receptor and GABAA receptor agonist.Formula:C23H27ClN4O3Purity:98%Color and Shape:SolidMolecular weight:442.94TPA-023B
CAS:TPA-023B: oral GABAA α2/α3 agonist (Kis: 0.73/2 nM), α1 antagonist (Ki: 1.8 nM), non-sedating anxiolytic.Formula:C21H15F2N5OPurity:98%Color and Shape:SolidMolecular weight:391.37CGP 7930
CAS:Positive allosteric modulator of GABAB receptorsFormula:C19H32O2Purity:98%Color and Shape:SolidMolecular weight:292.46Ro 41-3290
CAS:Ro 41-3290 is the desethylated derivative of Ro 41-3696, which is an agonist of nonbenzodiazepine partial at the benzodiazepine receptor.Formula:C24H21ClN2O3Purity:98%Color and Shape:SolidMolecular weight:420.89CPP-115
CAS:CPP-115 is a GABA-aminotransferase inhibitor and a high-affinity vigabatrin analogue.Formula:C7H9F2NO2Color and Shape:SolidMolecular weight:177.15BHF-177
CAS:BHF-177 is a positive allosteric modulator of the GABAB receptor. BHF-177 reduces self-administration of nicotine in animal studies.Formula:C19H20F3N3Color and Shape:SolidMolecular weight:347.38CGS8216
CAS:CGS8216 shows analgesic activity at high doses, has anxiolytic activity, and can be used to study immune system disorders.Formula:C16H11N3OPurity:98.53%Color and Shape:SolidMolecular weight:261.28PF-0713
CAS:PF 0713, a GABAA receptor agonist, is used as an intravenous sedative-hypnotic for general anaesthesia, ICU sedation, procedural sedation, chemotherapy.Formula:C14H22OPurity:98%Color and Shape:SolidMolecular weight:206.32DS2
CAS:Positive allosteric modulator of δ-subunit containing GABAA receptorsFormula:C18H12ClN3OSPurity:98%Color and Shape:SolidMolecular weight:353.83Lesogaberan
CAS:Lesogaberan: selective GABAB agonist, EC50 8.6 nM, Ki 5.1 nM in rats, weak GABAA affinity (Ki 1.4 μM).Formula:C3H9FNO2PPurity:98%Color and Shape:SolidMolecular weight:141.08MK-0343
CAS:MK0343 is an orally bioavailable GABAA receptor subtype-selective partial agonist and is a non-sedating anxiolytic.Formula:C19H17F2N7OPurity:98%Color and Shape:SolidMolecular weight:397.38RO 4938581
CAS:RO 4938581: potent GABAA α5 inverse agonist (Ki 4.6 nM); lower affinity for α1β3γ2a, α2β3γ2a, α3β3γ2a (Ki: 174, 185, 80 nM).Formula:C13H8BrF2N5Purity:98%Color and Shape:SolidMolecular weight:352.1417-PA
CAS:17-PA is a GABAA receptor antagonist.Formula:C25H34OPurity:98%Color and Shape:SolidMolecular weight:350.54CGP11952
CAS:CGP11952 is same the benzodiazepines in its pharmacological action and it also is an experimental benzodiazepine derivative.Formula:C21H21Cl2N5O2Purity:98%Color and Shape:SolidMolecular weight:446.33mGAT3/4-IN-1
CAS:mGAT3/4-IN-1 inhibits mGAT3/4 with pIC50: 5.31/5.24, reduces neuropathic pain in diabetic mice.Formula:C26H31ClN2O2S2Color and Shape:SolidMolecular weight:503.12Tracazolate hydrochloride
CAS:Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity.Formula:C16H25ClN4O2Purity:99.52%Color and Shape:SolidMolecular weight:340.85GABAA receptor agent 4
CAS:<p>Compound 1e is a potent γ-GABAAR antagonist with a Ki of 0.18 µM, offering immunomodulatory effects on T cell proliferation.</p>Formula:C17H24N2OColor and Shape:SolidMolecular weight:272.39Ro 19-4603
CAS:Benzodiazepine inverse agonistFormula:C15H17N3O3SPurity:98%Color and Shape:SolidMolecular weight:319.38NCS-382
CAS:γ-Hydroxybutyric acid antagonistFormula:C13H14O3Purity:98%Color and Shape:SolidMolecular weight:218.25Pregabalin arenacarbil
CAS:Pregabalin arenacarbil is a gabamimetic.Formula:C15H27NO6Color and Shape:SolidMolecular weight:317.38HZ166
CAS:HZ-166 is a positive GABAA receptor modulator and a GABAA receptor subtype-selective benzodiazepine site ligand.Formula:C21H16N4O2Purity:98%Color and Shape:SolidMolecular weight:356.38β-CCB
CAS:benzodiazepine receptor ligandFormula:C16H16N2O2Purity:98%Color and Shape:SolidMolecular weight:268.31Etbicyphat
CAS:Etbicyphat: potent GABA(A) antagonist, induces epileptiform activity, binds to GABA/benzodiazepine receptors.Formula:C6H11O4PColor and Shape:SolidMolecular weight:178.12GABAA receptor modulator-2
CAS:Compound 20: Selective, oral α5-GABAAR inhibitor, Ki: 4.1 nM. High stability, CNS safe.Formula:C22H22FN3O5SColor and Shape:SolidMolecular weight:459.49ZK93423
CAS:ZK93423: potent benzodiazepine agonist, IC50=1nM, non-selective, Ki=4.1-6nM for α1-α5 GABAA subunits.Formula:C23H22N2O4Color and Shape:SolidMolecular weight:390.43JY-XHe-053
CAS:JY-XHe-053 is a selective modulator of GABAA receptors.Formula:C22H16FN3O2Purity:98%Color and Shape:SolidMolecular weight:373.38HIE-124
CAS:HIE-124 is a central cervous system active anticonvulsant and ultra-short acting hypnotic.Formula:C10H12N2O3SPurity:98%Color and Shape:SolidMolecular weight:240.28Suclofenide
CAS:Suclofenide: a benzenesulfonamide anticonvulsant, effective in mouse seizure models, with side effects like lethargy and diarrhea.Formula:C16H13ClN2O4SPurity:98%Color and Shape:SolidMolecular weight:364.8(S)-Baclofen
CAS:(S)-Baclofen may treat hyperacusis and tinnitus by reducing auditory pathway excitation.Formula:C10H12ClNO2Purity:98%Color and Shape:SolidMolecular weight:213.66ABP-700
CAS:ABP-700 is a positive allosteric modulator of the GABAA receptor.Formula:C17H18N2O4Purity:98%Color and Shape:SolidMolecular weight:314.34RU 33965
CAS:RU 33965, a 3-cyclopropyl carbonyl imidazobenzodiazepine, act as a low-efficacy benzodiazepine receptor inverse agonist.Formula:C16H15N3O2Purity:98%Color and Shape:SolidMolecular weight:281.31MRK-623
CAS:MRK-623 (14k) is an oral GABA A agonist with high affinity for α1/α2/α3/α5 subunits and anxiolytic properties.Formula:C20H17FN4OColor and Shape:SolidMolecular weight:348.37DAA-1097
CAS:DAA-1097 is a novel ligand of peripheral benzodiazepine receptor.Formula:C24H24ClNO3Purity:98%Color and Shape:SolidMolecular weight:409.91(S)-3-Carboxy-4-hydroxyphenylglycine
CAS:group I metabotropic glutamate receptor antagonist and group II mGlu agonistFormula:C9H9NO5Purity:98%Color and Shape:SolidMolecular weight:211.17GABAA receptor agent 7
CAS:Compound 5c, a GABAA receptor modulator with anticonvulsant properties and low neurotoxicity, is promising for epilepsy research.Formula:C18H13ClN4OColor and Shape:SolidMolecular weight:336.77NAP-1
CAS:NAP-1 is an anesthetic that enhances CA1 brain inhibition in rats and causes tadpole sedation (EC50 = 0.53 μM).Formula:C20H18ClNO2Color and Shape:SolidMolecular weight:339.82Bamaluzole
CAS:Bamaluzole is an agonist of GABA receptor.Formula:C14H12ClN3OPurity:98%Color and Shape:SolidMolecular weight:273.72PNU-107484A
CAS:PNU-107484A is a unique GABA(A) receptor ligand.Formula:C18H23ClN6Purity:98%Color and Shape:SolidMolecular weight:358.87SL-651498
CAS:SL-651498, a GABAA receptor agonist, is used potentially for the treatment of anxiety.Formula:C23H20FN3O2Purity:98%Color and Shape:SolidMolecular weight:389.42TB 21007
CAS:GABAA receptor inverse agonistFormula:C15H17NO2S3Purity:98%Color and Shape:SolidMolecular weight:339.5GABAA receptor agent 6
CAS:GABAA receptor agent 6 (compound 2027) is a potent γ-GABAAR antagonist with low cellular membrane permeability (Ki = 0.56 μM) [1].Formula:C18H25N3O2Color and Shape:SolidMolecular weight:315.41(S)-SNAP5114
CAS:(S)-SNAP5114 is a selective inhibitor of GABA transport with IC50s of 5 μM for hGAT-3 and 21 μM for rGAT-2. (S)-SNAP5114 has anticonvulsant properties.Formula:C30H35NO6Purity:98.20%Color and Shape:SolidMolecular weight:505.6GS 39783
CAS:GS 39783 is a positive allosteric modulator (PAM) of GABABR, which reduces the motivational properties of alcohol and the conditioned reinforcement andFormula:C15H23N5O2SPurity:99.92%Color and Shape:SolidMolecular weight:337.44FG8119
CAS:FG8119 is a novel benzodiazepine agonist with potential anticonvulsant and antiepileptic activity for the study of neurological disorders.Formula:C17H15N5O2Purity:>99.99%Color and Shape:SolidMolecular weight:321.33TG41
CAS:TG41 is a GABAA receptors positive modulator.Formula:C18H13BrCl2N2O2Purity:98%Color and Shape:SolidMolecular weight:440.12SCH 50911
CAS:SCH 50911 is a selective GABA(B) receptor antagonist with IC50: 1.1 μM, boosting 3H overflow at IC50: 3 μM.Formula:C8H15NO3Purity:98%Color and Shape:SolidMolecular weight:173.21Anxiolytic/nonsedative agent-1
CAS:TCS 1205: Selective GABAA agonist, BzR affinity in bovine brain (Kis: 14-239 nM), α2 efficacy in vitro, anxioselective in vivo.Formula:C18H15N3O4Purity:98.61%Color and Shape:SolidMolecular weight:337.33Radequinil
CAS:<p>Radequinil is a benzodiazepine receptor partial inverse agonist. Rade quinil binds to GABA(-) and GABA(+) ligand (Kis: 5.15 and 6.11 nM, respectively).</p>Formula:C18H14N4O3Purity:98%Color and Shape:SolidMolecular weight:334.33Ciclotizolam
CAS:Ciclotizolam, a thienotriazolodiazepine derivative and partial GABAA receptor agonist, has low efficacy but similar affinity as brotizolam.Formula:C20H18BrClN4SColor and Shape:SolidMolecular weight:461.81ZAPA sulfate
CAS:GABAA receptors agonistFormula:C4H8N2O6S2Purity:98%Color and Shape:SolidMolecular weight:244.25GABAA receptor agent 8
CAS:Compound 5e, a GABAA receptor modulator, shows potent anticonvulsant effects with low neurotoxicity for epilepsy research.Formula:C19H16N4OColor and Shape:SolidMolecular weight:316.36AZD 3043
CAS:AZD 3043 (THRX 918661) is a modulator of the gamma-aminobutyric acid type A receptor, a novel sedative-hypnotic, and a potential short-acting anesthetic.Formula:C19H29NO5Purity:98.19% - 99.55%Color and Shape:SolidMolecular weight:351.44SH-053-S-CH3-2'F
CAS:SH-053-S-CH3-2'F is a potent and selective agonist of GABAA receptors.Formula:C23H18FN3O2Color and Shape:SolidMolecular weight:387.41(+)-Nipecotic acid
CAS:(+)-Nipecotic acid ((+)-β-Homoproline) is a specific inhibitor of GABA transport and uptake, capable of activating GABAA receptors.Formula:C6H11NO2Purity:99.38%Color and Shape:SolidMolecular weight:129.16CGP 36216 hydrochloride
CAS:CGP 36216 hydrochloride is a potent and selective antagonist of GABAB receptors (IC50: 43 μM).Formula:C5H14NO2PPurity:98%Color and Shape:SolidMolecular weight:151.14GABA-AT-IN-1
CAS:GABA-AT-IN-1 (Compound 6) is an inhibitor of γ-aminobutyric acid transaminase (GABA-AT) that crosses the blood-brain barrier.Formula:C23H18N2O6Color and Shape:SolidMolecular weight:418.4Alfadolone
CAS:Alfadolone is an anesthetic derivative of pregnanedione.Formula:C21H32O4Color and Shape:SolidMolecular weight:348.48CCD-3693
CAS:CCD-3693 is a gamma-aminobutyric acid (GABA) receptor agonist.Formula:C21H31F3O2Purity:98%Color and Shape:SolidMolecular weight:372.46Ro 22-8515
CAS:Ro 22-8515 is the ligand of benzodiazepine receptor.Formula:C18H12Cl2N2OColor and Shape:SolidMolecular weight:343.213α,21-Dihydroxy-5α-pregnan-20-one
CAS:3α,21-Dihydroxy-5α-pregnan-20-one (5alpha-THDOC) is a GABAA modulator that can be used in the study of Alzheimer's-like neurological diseases.Formula:C21H34O3Purity:98.00%Color and Shape:SolidMolecular weight:334.49UMB68 sodium
CAS:UMB-68 is a GHB receptor ligand with no affinity (IC(50) >100 microM) at GABA(A) or GABA(B) receptors.Formula:C6H12NaO3Color and Shape:SolidMolecular weight:155.149Carburazepam
CAS:Carburazepam is a derivate of benzodiazepines. Benzodiazepines are a class of psychoactive drugs.Formula:C17H16ClN3O2Purity:98%Color and Shape:SolidMolecular weight:329.78NNC052090
CAS:NNC052090 inhibits GABA uptake, favoring hBGT-1 (Ki=1.4μM), affects α1/D2 receptors (IC50=266/1632nM).Formula:C27H30N2O2Color and Shape:SolidMolecular weight:414.54Pipazethate
CAS:Pipipyrazine is a nonnarcotic oral cough suppressant, cough suppressant.Formula:C21H25N3O3SColor and Shape:SolidMolecular weight:399.51TCS 1105
CAS:TCS 1105 is a GABAA BZR ligand, blocking Sema3A and altering mouse anxiety, aggression, and social dominance.Formula:C17H13FN2O2Purity:99.75%Color and Shape:SolidMolecular weight:296.3ZK-91296
CAS:ZK-91296: GABA agonist, lowers anxiety without sedation, may target specific BZ receptor subtype.Formula:C23H22N2O4Purity:98%Color and Shape:SolidMolecular weight:390.43Chlormethiazole edisylate
CAS:Chlormethiazole edisylate is a positive allosteric modulator of the GABAA receptor. Chlormethiazole edisylate is a sedative and hypnotic.Formula:C8H14ClNO6S3Purity:98%Color and Shape:SolidMolecular weight:351.85COR628
CAS:COR628 is the GABA(B) receptor positive allosteric modulator.Formula:C16H23NO3SColor and Shape:SolidMolecular weight:309.42SCH-50910 free base
CAS:SCH-50910 is an antagonist of GABAB receptor.Formula:C8H15NO3Color and Shape:SolidMolecular weight:173.21Phaclofen
CAS:GABAB antagonistFormula:C9H13ClNO3PPurity:99.32%Color and Shape:White SolidMolecular weight:249.63Profadol hydrochloride
CAS:Profadol hydrochloride acts as a mixed agonist-antagonist of the μ-opioid receptor with analgesic activity.Formula:C14H22ClNOPurity:98%Color and Shape:SolidMolecular weight:255.78BGT1-IN-9
CAS:BGT1-IN-9 is an M1 muscarinic agonist.Formula:C5H10ClN3O2Color and Shape:SolidMolecular weight:179.605GABAA receptor agent 5
CAS:Compound 018 is a potent γ-GABAAR antagonist, Ki of 0.020 μM, with low membrane permeability.Formula:C21H25N3O2SPurity:99.39%Color and Shape:SolidMolecular weight:383.51Ro 14-7437
CAS:Ro 14-7437 is an antagonist of GABA-benzodiazepine receptor.Formula:C15H15N3O3Color and Shape:SolidMolecular weight:285.3Fengabine
CAS:Fengabine (SL-79229) is a GABA receptor agonist with antidepressant activity and is used to treat depression.Formula:C17H17Cl2NOPurity:99.37%Color and Shape:SolidMolecular weight:322.23BPDBA
CAS:BPDBA is an effective, selective, and non-competitive inhibitor of the betaine/GABA transporter (BGT-1), displaying inhibitory activity against human BGT-1 andFormula:C19H20Cl2N2OPurity:99.43% - 99.95%Color and Shape:SolidMolecular weight:363.28Golexanolone
CAS:Golexanolone can be used to study neurological diseases.Formula:C21H31NO2Purity:99.90% - 99.99%Color and Shape:SolidMolecular weight:329.48Nerisopam
CAS:<p>Nerisopam is an agonist of gamma-aminobutyric acid (GABA) receptor.</p>Formula:C18H19N3O2Purity:97.07%Color and Shape:SolidMolecular weight:309.36Ru-32514
CAS:Ru-32514 is a benzodiazepine receptor agonist.Formula:C18H17N3O2Purity:99.21%Color and Shape:SolidMolecular weight:307.35Suriclone
CAS:Suriclone (RP 31264), a cyclic pyrrolidone for anxiety, modulates GABA-A receptors without major sedation.Formula:C20H20ClN5O3S2Purity:99.21% - 99.73%Color and Shape:SolidMolecular weight:477.99Sarmazenil
CAS:Sarmazenil (Ro 15-3505) is a partial inverse agonist at the benzodiazepine receptor and is used in the study of chronic hepatic encephalopathy.Formula:C15H14ClN3O3Purity:99.46%Color and Shape:SolidMolecular weight:319.74DSP-0565
CAS:DSP-0565 is a broad-spectrum anti-epileptic with a high safety margin and effectiveness in several convulsant models.Formula:C14H12FNOPurity:99.51% - 99.56%Color and Shape:SolidMolecular weight:229.25Alpidem
CAS:Alpidem (Ananxyl), a non-sedative imidazopyridine anxiolytic, treats anxiety with high benzodiazepine receptor affinity.Formula:C21H23Cl2N3OPurity:99.56% - 99.97%Color and Shape:White To Off-White SolidMolecular weight:404.33Progabide
CAS:Progabide (SL 76002) is an agonist of the gamma-aminobutyric acid receptor.Formula:C17H16ClFN2O2Purity:99.68%Color and Shape:SolidMolecular weight:334.77Cirsimaritin
CAS:<p>Cirsimaritin has anti-bacterial, anti-inflammatory, anti-tumor, antioxidant effects, and protects kidneys; it weakly targets GABAA receptors.</p>Formula:C17H14O6Purity:99.9%Color and Shape:SolidMolecular weight:314.29Riluzole hydrochloride
CAS:Riluzole hydrochloride, an anticonvulsant Na+ channel blocker, inhibits GABA uptake (IC50: 43 µM).Formula:C8H6ClF3N2OSPurity:99.76%Color and Shape:SolidMolecular weight:270.66ELB-139
CAS:ELB-139 is a GABA A receptor agonist. ELB139 increases 5-HT in the striatum and prefrontal cortex of rats.Formula:C14H16ClN3OPurity:>99.99%Color and Shape:SolidMolecular weight:277.75Panadiplon
CAS:Panadiplon (FG 10571) is a selective gamma-aminobutyric acid receptor agonist and partial agonist of 5GABAA, a benzodiazepine receptor, used in the treatment ofFormula:C18H17N5O2Purity:98.30% - 98.94%Color and Shape:SolidMolecular weight:335.36DMCM hydrochloride
CAS:DMCM hydrochloride is a non-selective fully inverse agonist of benzodiazepine.Formula:C17H19ClN2O4Purity:99.56%Color and Shape:SolidMolecular weight:350.8Divaplon
CAS:Divaplon is a GABA receptor agonist (IC50: 0.056 µM) that displays non-sedating anxiolytic behavioral characteristics in a rat model of anxiety.Formula:C17H17N3O2Purity:97.44% - 98.25%Color and Shape:SolidMolecular weight:295.34L-838417
CAS:L-838417 is a GABAA receptor subtype-selective benzodiazepine site-selective ligand and GABAA receptor-positive modulator used in the study of anxiety disordersFormula:C19H19F2N7OPurity:98.12% - 99.70%Color and Shape:SolidMolecular weight:399.4RWJ-51204
CAS:<p>RWJ-51204: potent adenosine A2A blocker, GABA(A) partial agonist (IC50: 0.2-2 nM), neuroprotective, may treat Parkinson's.</p>Formula:C21H19F2N3O3Purity:99.57% - 99.95%Color and Shape:SolidMolecular weight:399.39Muscimol HBr
CAS:Muscimol HBr (Agarin HBr) is an agonist of GABAA receptor.Formula:C4H7BrN2O2Purity:98.13%Color and Shape:Off-White PowderMolecular weight:195.01Lirequinil
CAS:Lirequinil (Ro 41-3696) is a small molecule GABAA receptor agonist used to study neurological disorders.Formula:C26H25ClN2O3Purity:98.54%Color and Shape:SolidMolecular weight:448.94Saripidem
CAS:Saripidem (SL-85.0274) is a compound with anxiolytic activity.Formula:C19H20ClN3OPurity:98.42%Color and Shape:SolidMolecular weight:341.83NS-2710
CAS:NS-2710, a GABA receptor agonist, is used potentially for the treatment of anxiety.Formula:C22H20N4OPurity:99.7% - 99.82%Color and Shape:SolidMolecular weight:356.42NNC 05-711
CAS:NNC 05-711 (NO-711 hydrochloride) is a potent and selective inhibitor of GAT-1 (GABA transporter 1), exerting anticonvulsant and analgesic effects.Formula:C21H23ClN2O3Purity:99.92%Color and Shape:SolidMolecular weight:386.87mGAT3/4-IN-2
CAS:mGAT3/4-IN-2 are potent inhibitors of mGAT3/mGAT4 with their pIC50 values of 5.44 and 5.25, respectively.Formula:C26H32ClN3OS2Color and Shape:SolidMolecular weight:502.13CP-409092
CAS:<p>CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.</p>Formula:C17H19N3O2Purity:98%Color and Shape:SolidMolecular weight:297.35Diproqualone
CAS:Diproqualone, analogous to methaqualone, exhibits sedative, anxiolytic, anti-inflammatory, and analgesic properties [1].Formula:C12H14N2O3Color and Shape:SolidMolecular weight:234.255ADX71441
CAS:ADX71441, a GABAB PAM, lengthens urinary latencies, lessens events & volume, and may aid in alcoholism and bladder pain.Formula:C19H15ClF2N4O4Color and Shape:SolidMolecular weight:436.8(+)-Bicuculline methiodide
CAS:(+)-Bicuculline methiodide is a GABAA receptor blocker that blocks epileptogens and may be used in the study of neurological disorders.Formula:C21H20INO6Purity:99.24%Color and Shape:SolidMolecular weight:509.29Adipiplon
CAS:Adipiplon(NG2-73, NG273) is a novel selective gamma-aminobutyric acid (GABA) partial agonist.Formula:C18H18FN7Color and Shape:SolidMolecular weight:351.38CGP 64213
CAS:CGP 64213 is a GABAb receptor agonist.Formula:C26H36IN2O7PPurity:98%Color and Shape:SolidMolecular weight:646.45GMA-839
CAS:GMA-839 is a selective modulator of gamma-aminobutyric acid(A) receptors.Formula:C21H31F3O3Purity:98%Color and Shape:SolidMolecular weight:388.46FGIN-1-27
CAS:<p>FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).</p>Formula:C28H37FN2OPurity:99.86%Color and Shape:SolidMolecular weight:436.6PHP 501 trifluoroacetate
CAS:GABAA antagonistFormula:C20H21N3OPurity:98%Color and Shape:SolidMolecular weight:319.4CGP 55845 hydrochloride
CAS:CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC 50 of 6 nM which can be used in neurological research [1] [2].Formula:C18H23Cl3NO3PColor and Shape:SolidMolecular weight:438.71GABAA receptor agent 2 TFA
CAS:Potent GABAA antagonist; IC50: 24 nM (α1β2γ2), Ki: 28 nM (rat); inactive on human GABA transporters.Formula:C22H22F3N3O3Color and Shape:SolidMolecular weight:433.42L-822179
CAS:L-822179 (α5IA) is a selective inverse agonist for the Α5 subtype of GABAA receptor with higher intrinsic activity at the A5 subtype than other drugs.Formula:C17H14N8O2Purity:98.5% - 99.61%Color and Shape:SolidMolecular weight:362.35Org-21465
CAS:Org-21465, a gamma-aminobutyric acid (GABA) receptor agonist, is used potentially for the use of anesthesia.Formula:C27H43NO4Purity:98%Color and Shape:SolidMolecular weight:445.63(R)-4-Amino-3-hydroxybutyric Acid
CAS:(R)-4-Amino-3-hydroxybutyric acid, also known as (R)-GABOB, acts as a modulator of GABA receptors, specifically binding to both GABAA and GABAB receptors and blocking GABA reuptake in rat brain synaptosomes. Additionally, it serves as a GABAC receptor agonist, triggering currents in patch-clamp assays with Xenopus oocytes that express the human receptor. In vivo studies reveal its capability to suppress electrical discharges in the amygdala in cats undergoing N-amidinobenzamide-triggered seizures, indicating its potential therapeutic application in managing seizure disorders.Formula:C4H9NO3Color and Shape:SolidMolecular weight:119.12JM-1232
CAS:JM-1232 is a sedative and hypnotic drug being researched as a potential anesthetic.Formula:C24H27N3O2Color and Shape:SolidMolecular weight:389.49RPC425 free base
CAS:RPC425 is a noncompetitive inhibitors of the Betaine-γ-Aminobutyric Acid Transporter 1 (BGT1).Formula:C22H27NO2S2Purity:98%Color and Shape:SolidMolecular weight:401.59GABA-IN-2
CAS:GABA-IN-2 (Compound 5), a GABA inhibitor, exhibits both larvicidal and insecticidal properties, achieving an 87% mortality rate at a concentration of 50 mg/L [1Formula:C12H4Cl2F6N4SeColor and Shape:SolidMolecular weight:468.04TPA 023
CAS:<p>TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).</p>Formula:C20H22FN7OPurity:99.75%Color and Shape:SolidMolecular weight:395.43CGP 55845
CAS:CGP 55845: potent, selective GABAB blocker, IC50=5 nM, hinders agonist binding, reduces GABA/glutamate release.Formula:C18H22Cl2NO3PColor and Shape:SolidMolecular weight:402.25CGP-54626 free base
CAS:CGP-54626 is a selective antagonist of the GABAB receptor (IC50 = 4 nM ).Formula:C18H28Cl2NO3PPurity:98%Color and Shape:SolidMolecular weight:408.3Afizagabar
CAS:Afizagabar, a first-in-class α5-GABAAR antagonist, IC50: 585 nM, Ki: 66 nM, may boost memory.Formula:C19H12FN3O2SColor and Shape:SolidMolecular weight:365.38mGAT-IN-1
CAS:mGAT-IN-1 is a potent, non-selective GAT inhibitor that inhibits mGAT3 activity well (IC50: 2.5 μM, pIC50: 5.61).Formula:C28H34ClN3O2S2Color and Shape:SolidMolecular weight:544.17CGP 54626 hydrochloride
CAS:CGP 54626 hydrochloride is a GABAB receptor antagonist.Formula:C18H29Cl3NO3PPurity:98%Color and Shape:SolidMolecular weight:444.76Piperidine-4-sulfonic acid
CAS:Piperidine-4-sulfonic acid is a potent GABA agonist, demonstrating an IC50 value of 0.034 μM for the inhibition of H-GABA binding [1].Formula:C5H11NO3SPurity:98%Color and Shape:SolidMolecular weight:165.21SCS
CAS:SCS is a GABAA receptor antagonist.Formula:C14H12N2O3Purity:99.73%Color and Shape:SolidMolecular weight:256.26CGP36216 hydrochloride
CAS:CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].Formula:C5H15ClNO2PColor and Shape:SolidMolecular weight:187.6NO-711ME
CAS:NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.Formula:C22H24N2O3Purity:99.54%Color and Shape:SolidMolecular weight:364.44U 89843A
CAS:U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.Formula:C16H23N5Purity:99.62%Color and Shape:SolidMolecular weight:285.39PZ-II-029
CAS:<p>PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.</p>Formula:C18H15N3O3Purity:99.79%Color and Shape:SolidMolecular weight:321.33(-)-Bicuculline methochloride
CAS:<p>(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.</p>Formula:C21H20ClNO6Purity:98%Color and Shape:SolidMolecular weight:417.84L 663581
CAS:L 663581 is the benzodiazepine receptor partial agonist.Formula:C17H16ClN5O2Purity:98%Color and Shape:SolidMolecular weight:357.796,2'-Dihydroxyflavone
CAS:6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.Formula:C15H10O4Purity:99.44% - 99.67%Color and Shape:SolidMolecular weight:254.24NCS-382 sodium
CAS:NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological diseaseFormula:C13H13NaO3Purity:98%Color and Shape:SolidMolecular weight:240.23COR659
CAS:COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.Formula:C16H16ClNO3SPurity:99.75%Color and Shape:SolidMolecular weight:337.82GABAA receptor agonist 2
Compound 4c, a potent GABAA agonist with anti-depressive effects in mouse FST/TST, shows promise in depression research.Formula:C22H36O5Color and Shape:SolidMolecular weight:380.52SGE-516
CAS:SGE516: neuroactive steroid, enhances GABAA, lowers neuronal activity, protects from seizures.Formula:C23H35N3O2Purity:98%Color and Shape:SolidMolecular weight:385.54Tuclazepam
CAS:Tuclazepam (KC 1956) is a derivative of the benzodiazepine class of drugs, exhibiting anti-anxiety and sedative properties.Formula:C17H16Cl2N2OColor and Shape:SolidMolecular weight:335.23TP003
CAS:<p>TP003 is a novel non-selective GABAA receptor benzodiazepine site agonist with affinity for α1β2gam2, α2β3gam2, α3β3gam2, α5β2gam2, EC50 of 20.3, 10.6, 3.24, 5.</p>Formula:C23H16F3N3OPurity:99.17%Color and Shape:SolidMolecular weight:407.39EF1502 free base
CAS:EF1502 is a potent and selective GABA transporter inhibitor.Formula:C22H26N2O2S2Purity:98%Color and Shape:SolidMolecular weight:414.58Moxetomidate
CAS:<p>Moxetomidate is a GABAA receptor (GABAA receptor) agonist with hypnotic properties.</p>Formula:C15H18N2O3Color and Shape:SolidMolecular weight:274.315GABA-IN-4
CAS:GABA-IN-4 (Compound 17) is a derivative of N-(indol-3-ylglyoxylyl)benzylamine. It exhibits high affinity for the benzodiazepine receptor (BzR), the binding site within the GABAA receptor complex, with a Ki value of 67 nM. Benzodiazepines are widely used as anxiolytic, sedative-hypnotic, and anticonvulsant agents.Formula:C17H13ClN2O2Color and Shape:SolidMolecular weight:312.75Cyproflanilide
CAS:Cyproflanilide is a GABAR antagonist that exhibits high activity against a variety of pests, including those from the Lepidoptera, Coleoptera, and Thysanoptera orders.Formula:C28H17BrF12N2O2Color and Shape:SolidMolecular weight:721.33BGT1-IN-1
CAS:BGT1-IN-1 (compound 9) is an effective inhibitor of BGT1, demonstrating IC50 values of 13.9 µM for hBGT1 and 58.3 µM for GAT3. It exhibits no cytotoxic effects and possesses neuroprotective activity.Formula:C6H9NO2Color and Shape:SolidMolecular weight:127.14Fletazepam
CAS:Fletazepam, a benzodiazepine derivative, exhibits sedative, anti-anxiety, and muscle-relaxant properties. It is utilized in neurological research.Formula:C17H13ClF4N2Color and Shape:SolidMolecular weight:356.74CGS-9895
CAS:CGS-9895 is a GABA antagonist that operates by interacting with the benzodiazepine binding site on GABA receptors containing the γ subunit (ag).Formula:C17H13N3O2Molecular weight:291.304β-CCM
CAS:β-CCM is a benzodiazepine receptor inverse agonist with anxiogenic and convulsant effects. It enhances emotional reactivity and reduces interference sensitivity in spatial working memory tasks. β-CCM is applicable in research related to anxiety disorders.Formula:C13H10N2O2Molecular weight:226.231GABAA receptor agonist 1
Compound 3e, a potent GABAA agonist, targets GABA sites and has potential anti-depressive effects in mice.Formula:C20H30O3Color and Shape:SolidMolecular weight:318.45ZK 93426 hydrochloride
CAS:benzodiazepine receptor antagonist,competitiveFormula:C18H21ClN2O3Purity:98%Color and Shape:SolidMolecular weight:348.82S-8510 phosphate
CAS:S-8510 phosphate is an agonist of inverse Benzodiazepine (BDZ) receptor(Kis of 34.6 nM, 36.2 nM for –GABA and +GABA respectively).Formula:C12H13N4O6PPurity:98%Color and Shape:SolidMolecular weight:340.23Refisolone
CAS:Refisolone is an antagonist of the GABAA receptor.Formula:C18H24O3Molecular weight:288.381Thiomuscimol hydrobromide
CAS:Thiomuscimol hydrobromide is an agonist of GABAA receptor.Formula:C4H6N2OSPurity:98%Color and Shape:SolidMolecular weight:130.17Gabaculine HCl
CAS:Gabaculine, an irreversible GABA-T inhibitor (Ki: 2.9 μM), impacts plastid development and affects DPOR/GluTR levels.Formula:C7H10ClNO2Color and Shape:SolidMolecular weight:175.61(-)-Bicuculline methobromide
CAS:(-)-Bicuculline methobromide is a potent antagonist of GABAA receptor .Formula:C21H20BrNO6Color and Shape:WhiteMolecular weight:462.292-AEMP TFA
CAS:2-AEMP TFA is a potent and rapidly acting antagonist of GABA(A)-ρ1 receptors. 2-AEMP is an analog of GABA.Formula:C3H10NO3PPurity:98%Color and Shape:SolidMolecular weight:139.091Alfadolone acetate
CAS:Alfadolone acetate is a gamma-aminobutyric acid (GABA) receptor agonist.Formula:C23H34O5Color and Shape:SolidMolecular weight:390.513-Methylglutaconic acid
CAS:3-Methylglutaconic acid, a primary metabolite accumulating in 3-Methylglutaconic aciduria (MGTA), induces lipid and protein oxidation, while diminishing non-enzymatic antioxidant defenses in cerebral cortex supernatants, thereby promoting oxidative stress in the cerebral cortex. This compound is utilized in research concerning brain damage diseases [1].Formula:C6H8O4Purity:98%Color and Shape:SolidMolecular weight:144.13Pipequaline
CAS:Pipequaline (PK-8165) is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It possesses a novel chemical structure that is not closely related to other drugs of this type. The drug has a similar pharmacological profile to the benzodiazepine family of drugs, but with mainly anxiolytic properties and very little sedative, amnestic or anticonvulsant effects, and so is classified as a nonbenzodiazepine anxiolytic.Formula:C22H24N2Purity:98%Color and Shape:SolidMolecular weight:316.44Ref: TM-T4655
Discontinued productPazinaclone
CAS:<p>Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.</p>Formula:C25H23ClN4O4Purity:97.79% - 99.07%Color and Shape:SolidMolecular weight:478.93CGP 44532
CAS:CGP 44532 a GABAB receptor agonist.Formula:C4H12NO3PPurity:98%Color and Shape:SolidMolecular weight:153.12Xilmenolone
CAS:<p>Xilmenolone acts as a positive allosteric modulator of the GABA_A receptor [1].</p>Formula:C26H37N3O2Purity:98%Color and Shape:SolidMolecular weight:423.59CGP 56999A
CAS:CGP 56999A is a GABA(B) receptor antagonist; it boosts BDNF and reduces dopamine loss in rat striatum.Formula:C19H30NO5PPurity:98%Color and Shape:SolidMolecular weight:383.42
