GABA Receptor
GABA receptors are the primary inhibitory neurotransmitter receptors in the central nervous system, playing a critical role in regulating neuronal excitability and maintaining the balance between excitation and inhibition. GABA receptor dysfunction is implicated in various neurological and psychiatric disorders, including epilepsy, anxiety, and depression. At CymitQuimica, we provide a comprehensive range of GABA receptor modulators to support your research in neurobiology, mental health, and therapeutic development.
Found 371 products of "GABA Receptor"
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Azocarnil
Azocarnil is a GABAergic agonist-enhancer used in neurological system research.Color and Shape:Odour SolidGAD65(247-266) epitope TFA
GAD65(247-266) epitope TFA, a T cell epitope derived from islet antigens, exhibits competitive binding to the type I diabetes-associated molecule I-A g7, albeitFormula:C111H174F3N27O29S4Purity:98%Color and Shape:SolidMolecular weight:2535.99AHN-683
CAS:AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.Formula:C42H32FN3O7Purity:98%Color and Shape:SolidMolecular weight:709.72MmTx1 toxin
Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor's sensitivity to its agonist [1].Formula:C295H455N95O97S10Purity:98%Color and Shape:SolidMolecular weight:7205Brexanolone caprilcerbate
CAS:Brexanolone caprilcerbate is an effective positive allosteric modulator of the GABAA receptor.Formula:C48H78O12Color and Shape:SolidMolecular weight:847.13(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS:(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.Formula:C6H11NO2Color and Shape:SolidMolecular weight:129.16Ion Channel Targeted Library
A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;
Color and Shape:Odour SolidWithasomniferolide B
CAS:Withasomniferolide B, a withanolide from Withania somnifera root, activates GABAA receptors.Formula:C28H36O4Color and Shape:SolidMolecular weight:436.58GABA receptor Antagonist 1
GABA receptor Antagonist 1 (compound 7w) effectively inhibits the Px RDL1 GABAR at an IC50 of 7.08 nmol/L and demonstrates insecticidal efficacy against P.Purity:98%Color and Shape:Odour SolidGABOB (β-hydroxy-GABA)
CAS:GABOB, an epilepsy treatment, is GABA's analogue and may act as a neurotransmitter.Formula:C4H9NO3Color and Shape:White To Light Yellow Crystal PowderMolecular weight:119.12Emamectin B1a
CAS:Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.
Formula:C49H75NO13Color and Shape:SolidMolecular weight:886.133Cinazepam
CAS:Cinazepam is a GABAA receptor partial agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders.Formula:C19H14BrClN2O5Color and Shape:SolidMolecular weight:465.68Pikamilone Sodium
CAS:Pikamilone Sodium is a prodrug of GABA used for therapy of neurogenic bladder in spinal and benign prostatic hyperplasia.Formula:C10H11N2NaO3Purity:98%Color and Shape:SolidMolecular weight:230.2Furosemide
CAS:Furosemide is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used for edema and chronic renal insufficiency.Formula:C12H11ClN2O5SPurity:99.32% - 99.89%Color and Shape:Crystals From Aqueous Ethanol Tasteless (Ntp 1992)Molecular weight:330.744GABA-A Receptor Ligand-1
GABA-A Receptor Ligand-1 (Compound 4) is a ligand for the GABA-A receptor with a pKi of 7.27. It alleviates mitochondrial dysfunction, promotes neurite outgrowth and neuronal regeneration, and demonstrates neuroprotective effects in a rat ischemic stroke model.Formula:C20H20FN3OColor and Shape:SolidMolecular weight:337.39112,14-Dichlorodehydroabietic acid
CAS:12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.Formula:C20H26Cl2O2Color and Shape:SolidMolecular weight:369.333-Aminopropylphosphonic Acid
CAS:3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding
Formula:C3H10NO3PPurity:99.84%Color and Shape:Light Yellow LiquidMolecular weight:139.09Desalkylgidazepam
CAS:Desalkylgidazepam, a benzodiazepine compound, is a metabolite of gidazepam. It is capable of activating both GABA A-type receptors and the translocator protein (TSPO).Formula:C15H11BrN2OColor and Shape:SolidMolecular weight:315.173-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt)
CAS:3-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt) can be used in related research in the field of life sciences.Formula:C10H10ClNaO3Color and Shape:SolidMolecular weight:236.63S-8510 free base
CAS:S-8510 is a GABA-A receptor inverse agonist enhancing memory, LTP, and neurotransmitters in rats.Formula:C12H10N4O2Color and Shape:SolidMolecular weight:242.23GABA-IN-1
GABA-IN-1 (Compound 6), a GABA inhibitor, exhibits larvicidal and insecticidal properties, achieving a mortality rate of 93% at a concentration of 50 mg/L [1].Color and Shape:Odour SolidFipronil sulfone
CAS:Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.Formula:C12H4Cl2F6N4O2SPurity:98%Color and Shape:SolidMolecular weight:453.14Chrodrimanin B
CAS:Chrodrimanin B is a useful organic compound for research related to life sciences. The catalog number is T126052 and the CAS number is 132196-54-4.Formula:C27H32O8Color and Shape:SolidMolecular weight:484.545MIDD0301
CAS:MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.
Formula:C19H13BrFN3O2Purity:98%Color and Shape:SolidMolecular weight:414.23Lesogaberan napadisylate
CAS:Lesogaberan (AZD-3355) is a selective GABAB agonist with EC50 of 8.6 nM, Ki of 5.1 nM in rats, and acts peripherally on the esophageal sphincter.Formula:C13H17FNO5PSColor and Shape:SolidMolecular weight:349.31KGP-25
KGP-25 is an inhibitor of the voltage-gated sodium channel 1.8 (Nav1.8), utilized for analgesia by targeting the peripheral nervous system (PNS). Additionally, it targets the γ-aminobutyric acid subtype A receptor (GABAA) in the central nervous system (CNS) for use as a general anesthetic.Color and Shape:Odour Solidepi-Aszonalenin A
CAS:epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.Formula:C25H25N3O3Color and Shape:SolidMolecular weight:415.48γ-Acetylenic GABA hydrochloride
CAS:γ-Acetylenic GABA hydrochloride is a GABA transaminase inhibitor.Formula:C6H10ClNO2Purity:97.83% - 99.44%Color and Shape:SolidMolecular weight:163.6Sandaracopimaric acid
CAS:Sandaracopimaric acid, an anti-inflammatory diterpene, relaxes pulmonary arteries with an EC50 of 43.93 μM.Formula:C20H30O2Color and Shape:SolidMolecular weight:302.456,7-dimethylisatin
CAS:6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.Formula:C10H9NO2Purity:98.98%Color and Shape:SolidMolecular weight:175.18Neurotransmitter Receptor Compound Library
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；
Color and Shape:Odour SolidCAY10787
CAS:CAY10787, an oxysterol, inhibits GABAA receptors (IC50s: 1-1.5μM) and lessens GABA responses in mouse DRG neurons.Formula:C27H42OColor and Shape:SolidMolecular weight:382.632GABAA receptor modulator-3
GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.Formula:C18H22O2Color and Shape:SolidMolecular weight:270.37RuBi-GABA
CAS:Ruthenium-bipyridine-triphenylphosphine caged GABAFormula:C42H39F6N5O2P2RuPurity:98%Color and Shape:SolidMolecular weight:922.8CGP 35348
CAS:CGP 35348 是 GABAB 受体的选择性拮抗剂 (EC50 = 34 μM)。 CGP 35348 可用于研究白化新生小鼠脑损伤后的神经肌肉协调和空间学习。Formula:C8H20NO4PPurity:≥98%Color and Shape:SolidMolecular weight:225.22Antidepressant agent 3
Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.Formula:C17H30ClN5O2SColor and Shape:SolidMolecular weight:403.97Riluzole-13C,15N2
CAS:Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.Formula:CC7H5F3OS15N2Color and Shape:SolidMolecular weight:237.18(Iso)-Atagabalin HCl
CAS:(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.Formula:C10H20ClNO2Purity:99.88% - >99.99%Color and Shape:SoildMolecular weight:221.72Furosemide sodium
CAS:Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.Formula:C12H10ClN2NaO5SPurity:99.52% - >99.99%Color and Shape:SolidMolecular weight:352.73Flufiprole
CAS:Flufiprole is used as a phenylpyrazole pesticide. It has enantioselective metabolism in human and rat liver microsomes.Formula:C16H10Cl2F6N4OSColor and Shape:SolidMolecular weight:491.24Antidepressant agent 4
Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.Formula:C19H38ClN5O2SColor and Shape:SolidMolecular weight:436.06Nitrazolam
CAS:Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.Formula:C17H13N5O2Color and Shape:SolidMolecular weight:319.32GABAA receptor modulator-4
GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.Formula:C15H17BrO4SColor and Shape:SolidMolecular weight:373.265α-Androst-16-en-3α-ol
CAS:5α-Androst-16-en-3α-ol is a steroid pheromone that has been found in boar testes and human male axillary sweat and has diverse biological activities.1,2ItFormula:C19H30OColor and Shape:SolidMolecular weight:274.448Guvacine hydrobromide
CAS:Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake.Formula:C6H10BrNO2Purity:98%Color and Shape:SolidMolecular weight:208.05Etifoxine
CAS:Etifoxine targets β2/β3 GABAA receptors, is anxiolytic in humans/rodents, boosts GABAA, binds TSPO, aids axon regeneration, no sedative effects.Formula:C17H17ClN2OPurity:98%Color and Shape:SolidMolecular weight:300.78CGP 36742
CAS:CGP 36742 blocks GABAB receptor, crosses blood-brain barrier, aids depression treatment (IC50: 32 μM).Formula:C7H18NO2PColor and Shape:SolidMolecular weight:179.2Valnoctamide
CAS:Valnoctamide (Valmethamide) has antiepileptic and anticonvulsant activity and may be used in the study of neurological disorders.Formula:C8H17NOPurity:98%Color and Shape:SolidMolecular weight:143.23Vigabatrin Hydrochloride
CAS:Vigabatrin Hydrochloride (γ-Vinyl-GABA hydrochloride) is a structural analog of the GABA, irreversibly inhibiting the catabolism of GABA by GABA transaminase.Formula:C6H11NO2·HClPurity:98%Color and Shape:SolidMolecular weight:165.62
