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PDE

PDE

Phosphodiesterases (PDEs) are enzymes that hydrolyze cyclic nucleotides, such as cAMP and cGMP, into their inactive forms, playing a key role in regulating intracellular signaling pathways. PDE inhibitors are used in the treatment of various conditions, including cardiovascular diseases, erectile dysfunction, and respiratory disorders, due to their ability to modulate cyclic nucleotide levels. At CymitQuimica, we provide a range of PDE inhibitors to support your research in cell signaling, pharmacology, and therapeutic development.

Found 165 products of "PDE"

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  • PDE4B-IN-4
    Targetmol
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    PDE4B-IN-4

    <p>PDE4B-IN-4 is an inhibitor of PDE4B (IC50: 2.82 nM) and TNF-α (IC50: 7.20 nM). It demonstrates anti-inflammatory properties by reducing neutrophilia in a mouse model of lipopolysaccharide (LPS)-induced sepsis.</p>
    Formula:C26H27N5O5
    Color and Shape:Solid
    Molecular weight:489.52

    Ref: TM-T207245

  • BAY 2666605
    Targetmol
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    BAY 2666605

    CAS:
    <p>BAY 2666605 is an orally active inhibitor of PDE3A and PDE3B with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 has anticancer effects.</p>
    Formula:C17H12F4N2O2
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:352.28

    Ref: TM-T9805

  • BC 11-38
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    BC 11-38

    CAS:
    <p>BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).</p>
    Formula:C15H16N2OS2
    Purity:98.95% - 99.28%
    Color and Shape:Solid
    Molecular weight:304.43

    Ref: TM-T21865

  • Arofylline
    Targetmol
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    Arofylline

    CAS:
    <p>Arofylline (LAS 31025) is a PDE4 inhibitor and can be used for asthma studies.</p>
    Formula:C14H13ClN4O2
    Purity:98.19%
    Color and Shape:Solid
    Molecular weight:304.73

    Ref: TM-T9816

  • FCPR03
    Targetmol
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    FCPR03

    CAS:
    <p>FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 nM, and 60 nM for PDE4B1, PDE4D7, and PDE4 catalytic domain, respectively.</p>
    Formula:C15H19F2NO3
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:299.31

    Ref: TM-T39341

  • OPC18750 HCl
    Targetmol
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    OPC18750 HCl

    CAS:
    <p>OPC18750 HCl is a phosphodiesterase inhibitor with positive inotropic effects that can be used to study asthma, cancer, diabetes, and psychiatric disorders.</p>
    Formula:C20H23ClN2O4
    Purity:98.92%
    Color and Shape:Soild
    Molecular weight:390.86

    Ref: TM-T83974

  • cis-Tadalafil
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    cis-Tadalafil

    CAS:
    <p>Tadalafil: a carboline-based PDE5 inhibitor, treats erectile dysfunction, prostatic hyperplasia, and pulmonary hypertension.</p>
    Formula:C22H19N3O4
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:389.4

    Ref: TM-T20024

  • Enpp-1-IN-14
    Targetmol
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    Enpp-1-IN-14

    CAS:
    <p>Enpp-1-IN-14: potent ENPP1 inhibitor, IC50 = 32.38 nM, exhibits anti-tumor properties.</p>
    Formula:C15H22ClN5O4S
    Purity:99.83%
    Color and Shape:Soild
    Molecular weight:403.88

    Ref: TM-T60105

  • PDE5-IN-9
    Targetmol
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    PDE5-IN-9

    CAS:
    <p>WAY-639921 treats cardiovascular and respiratory conditions by inhibiting PDE1c.</p>
    Formula:C18H14N4S
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:318.4

    Ref: TM-T67941

  • ONO-8430506
    Targetmol
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    ONO-8430506

    CAS:
    <p>ONO-8430506 is an orally available, potent autotaxin (ATX)/ENPP2 inhibitor (IC90: 100 nM) that inhibits ATX activity in mouse plasma.</p>
    Formula:C27H28FN3O3
    Purity:98.34%
    Color and Shape:Solid
    Molecular weight:461.53

    Ref: TM-T38759

  • Acetildenafil
    Targetmol
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    Acetildenafil

    CAS:
    <p>Acetildenafil is an analog of the phosphodiesterase inhibitor sildenafil.</p>
    Formula:C25H34N6O3
    Color and Shape:Off-White To Pale Yelow Solid
    Molecular weight:466.58

    Ref: TM-T7876

  • WAY-313170
    Targetmol
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    WAY-313170

    CAS:
    <p>WAY-313170 Inhibits hedgehog signaling and phosphodiesterase.</p>
    Formula:C19H17ClN2O2S2
    Purity:99.3%
    Color and Shape:Solid
    Molecular weight:404.93

    Ref: TM-T77603

  • Oglemilast
    Targetmol
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    Oglemilast

    CAS:
    <p>Oglemilast (GRC 3886) suppresses pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo.</p>
    Formula:C20H13Cl2F2N3O5S
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:516.3

    Ref: TM-T16379

  • (1R,2R)-MK-8189
    Targetmol
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    (1R,2R)-MK-8189

    CAS:
    <p>(1R,2R)-MK-8189 is an isomer of MK-8189, a potent and selective pyrimidine PDE10A inhibitor.</p>
    Formula:C19H22N6OS
    Purity:>99.99% - >99.99%
    Color and Shape:Soild
    Molecular weight:382.48

    Ref: TM-T73462L

  • Dazonone
    Targetmol
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    Dazonone

    CAS:
    <p>Dazonone (Imidazo[2,1-b]quinazolin-2(3H)-one, 6-chloro-1,5-dihydro-3-methyl-) is a specific PDE III inhibitors.</p>
    Formula:C11H10ClN3O
    Purity:99.54% - 99.73%
    Color and Shape:Solid
    Molecular weight:235.67

    Ref: TM-T9871

  • ENPP1 Inhibitor C
    Targetmol
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    ENPP1 Inhibitor C

    CAS:
    <p>ML-354 (VU0099704) is an antagonist with and PAR4 for the study of cardiovascular diseases.</p>
    Formula:C15H18N6
    Purity:99.28%
    Color and Shape:Solid
    Molecular weight:282.34

    Ref: TM-T37431

  • N-Ethyl tadalafil
    Targetmol
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    N-Ethyl tadalafil

    CAS:
    <p>N-Ethyl tadalafil (NEthyl tadalafil) is a PDE inhibitor used in the study of cardiovascular disease.</p>
    Formula:C23H21N3O4
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:403.43

    Ref: TM-T19998

  • CymitQuimica logo
    Targetmol
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    Anti-ALDH7A1 Antibody (6G475)

    <p>Anti-ALDH7A1 Antibody (6G475) is a Mouse antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (6G475) can be used in IHC-P.</p>
    Color and Shape:Odour Liquid

    Ref: TM-TMAY-01932

  • CymitQuimica logo
    Targetmol
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    Anti-ALDH7A1 Antibody-FITC (5P692)

    <p>Anti-ALDH7A1 Antibody-FITC (5P692) is a FITC-conjugated Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody-FITC (5P692) can be used in FCM.</p>
    Color and Shape:Odour Liquid

    Ref: TM-TMAY-01933F

  • BAY 73-6691 racemate
    Targetmol
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    BAY 73-6691 racemate

    CAS:
    <p>BAY 73-6691 racemate (Rac-BAY 73-6691) is a phosphodiesterase 9A (PDE9A) inhibitor, useful for studying Parkinson’s disease.</p>
    Formula:C15H12ClF3N4O
    Color and Shape:Solid
    Molecular weight:356.73

    Ref: TM-T10481