PDE
Phosphodiesterases (PDEs) are enzymes that hydrolyze cyclic nucleotides, such as cAMP and cGMP, into their inactive forms, playing a key role in regulating intracellular signaling pathways. PDE inhibitors are used in the treatment of various conditions, including cardiovascular diseases, erectile dysfunction, and respiratory disorders, due to their ability to modulate cyclic nucleotide levels. At CymitQuimica, we provide a range of PDE inhibitors to support your research in cell signaling, pharmacology, and therapeutic development.
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TAK-915
CAS:1476727-50-0
TAK-915: potent, brain-ready PDE2A inhibitor, 0.61 nM IC50, 4100x selectivity over PDE1A.
Formula:
C19H18F4N4O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
458.36
Ref: TM-T16976
| 5mg | 725.00 € | ||
| 10mg | 1,159.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
BAY 2666605
CAS:2275774-60-0
BAY 2666605 is an orally active inhibitor of PDE3A and PDE3B with IC50s of 87 …
Formula:
C17H12F4N2O2
Purity:
99.98%
Color and Shape:
Liquid
Molecular weight:
352.28
Ref: TM-T9805
| 1mg | 97.00 € | ||
| 5mg | 235.00 € | ||
| 10mg | 376.00 € | ||
| 25mg | 828.00 € | ||
| 50mg | 1,320.00 € | ||
| 100mg | 2,118.00 € | ||
| 1mL*10mM (DMSO) | 259.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
Enpp/Carbonic anhydrase-IN-1
CAS:2883495-35-8
Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent inhibitor of Enpp and carbonic anhydrase.
Formula:
C23H25NO4S
Purity:
100%
Color and Shape:
Soild
Molecular weight:
411.51
Ref: TM-T67775
| 5mg | 46.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 117.00 € | ||
| 50mg | 187.00 € | ||
| 100mg | 306.00 € | ||
| 200mg | 434.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
FCPR03
CAS:1917347-65-9
FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 …
Formula:
C15H19F2NO3
Purity:
100.00%
Color and Shape:
Liquid
Molecular weight:
299.31
Ref: TM-T39341
| 1mg | 52.00 € | ||
| 2mg | 75.00 € | ||
| 5mg | 116.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 311.00 € | ||
| 50mg | 444.00 € | ||
| 100mg | 605.00 € | ||
| 200mg | 815.00 € | ||
| 1mL*10mM (DMSO) | 128.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
cis-Tadalafil
CAS:171596-27-3
Tadalafil: a carboline-based PDE5 inhibitor, treats erectile dysfunction, prostatic hyperplasia, and pulmonary hypertension.
Formula:
C22H19N3O4
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
389.4
Ref: TM-T20024
| 1mg | 279.00 € | ||
| 5mg | 685.00 € | ||
| 10mg | 938.00 € | ||
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
BC 11-38
CAS:686770-80-9
BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 …
Formula:
C15H16N2OS2
Purity:
97.71% - 98.72%
Color and Shape:
Solid
Molecular weight:
304.43
Ref: TM-T21865
| 2mg | 47.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 202.00 € | ||
| 50mg | 329.00 € | ||
| 100mg | 527.00 € | ||
| 200mg | 747.00 € | ||
| 500mg | 1,121.00 € | ||
| 1mL*10mM (DMSO) | 90.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
ONO-8430506
CAS:1354805-08-5
ONO-8430506 is an orally available, potent autotaxin (ATX)/ENPP2 inhibitor (IC90: 100 nM) that inhibits ATX …
Formula:
C27H28FN3O3
Purity:
97.05%
Color and Shape:
Liquid
Molecular weight:
461.53
Ref: TM-T38759
| 1mg | 156.00 € | ||
| 5mg | 368.00 € | ||
| 10mg | 509.00 € | ||
| 25mg | 770.00 € | ||
| 50mg | 1,035.00 € | ||
| 100mg | 1,396.00 € | ||
| 200mg | 1,882.00 € | ||
| 1mL*10mM (DMSO) | 409.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
Deltasonamide 2 hydrochloride
Deltasonamide 2 hydrochloride is a competitive high-affinity PDEδ inhibitor with a Kd of approximately 385 …
Formula:
C30H40Cl2N6O4S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
683.71
Ref: TM-T10994L
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Mar 2025
EMD57439
CAS:148714-88-9
EMD57439 is a selective PDE-III inhibitor, showing no significant increase in c-AMP concentration and producing …
Formula:
C22H23N3O4S
Purity:
98% - 99.38%
Color and Shape:
Solid
Molecular weight:
425.5
Ref: TM-T25373
| 1mg | 115.00 € | ||
| 5mg | 265.00 € | ||
| 10mg | 386.00 € | ||
| 25mg | 610.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
ENPP1 Inhibitor C
CAS:2378640-92-5
ML-354 (VU0099704) is an antagonist with and PAR4 for the study of cardiovascular diseases.
Formula:
C15H18N6
Color and Shape:
Liquid
Molecular weight:
282.34
Ref: TM-T37431
| Undefined size | To inquire |
Estimated delivery in United States, on Tuesday 4 Mar 2025
UK 227786
CAS:150452-21-4
UK 227786 is an inhibitor of phosphodiesterase 5 (PDE5), used for treatment of prostatic diseases.
Formula:
C22H22Cl2N4O4
Purity:
100%
Color and Shape:
Soild
Molecular weight:
477.34
Ref: TM-T11220L
| 1mg | 115.00 € | ||
| 2mg | 172.00 € | ||
| 5mg | 255.00 € | ||
| 10mg | 375.00 € | ||
| 25mg | 562.00 € | ||
| 50mg | 792.00 € | ||
| 100mg | 1,064.00 € | ||
| 500mg | 2,147.00 € | ||
| 1mL*10mM (DMSO) | 304.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
Pumafentrine
CAS:207993-12-2
Pumafentrine(BY 343) is a dual PDE3/PDE4 inhibitor that reduces clinical scores and TNF expression in …
Formula:
C29H39N3O3
Purity:
99.79%
Color and Shape:
Liquid
Molecular weight:
477.64
Ref: TM-T71691
| 1mg | 185.00 € | ||
| 5mg | 442.00 € | ||
| 10mg | 645.00 € | ||
| 25mg | 1,017.00 € | ||
| 50mg | 1,359.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
ent-Tadalafil
CAS:629652-72-8
ent-Tadalafil (ent-IC-351), compound (6S,12aS), is a inactive cis-enantiomer of compound (6R,12aS).
Formula:
C22H19N3O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
389.4
Ref: TM-T11206
| 25mg | 740.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
Nauclefine
CAS:57103-51-2
Nauclefine, a plant alkaloid, triggers cancer cell death through PDE3A-SLFN12, binding but not inhibiting PDE3A.
Formula:
C18H13N3O
Purity:
99.92%
Color and Shape:
Solid
Molecular weight:
287.32
Ref: TM-TN6120
| 1mg | 116.00 € | ||
| 2mg | 170.00 € | ||
| 5mg | 255.00 € | ||
| 10mg | 375.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Mar 2025
Vardenafil dihydrochloride
CAS:224789-15-5
Vardenafil dihydrochloride (Levitra) is a new type PDE inhibitor with IC50 of 0.7 and 180 …
Formula:
C23H34Cl2N6O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
561.52
Ref: TM-T4480
| 25mg | 50.00 € | ||
| 50mg | 92.00 € | ||
| 100mg | 150.00 € | ||
| 200mg | 256.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
BI 1015550
CAS:1423719-30-5
Nerandomilast (BI 1015550) is an orally active PDE4B inhibitor with IC50 of 7.2 nM.Cost-effective and …
Formula:
C20H25ClN6O2S
Purity:
100% - 99.71%
Color and Shape:
Soild
Molecular weight:
448.97
Ref: TM-T72031
| 1mg | 65.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 378.00 € | ||
| 50mg | 560.00 € | ||
| 100mg | 800.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
T-0156
CAS:324572-92-1
T-0156 is a PEG5 inhibitor that inhibits the hydrolysis of cyclic guanosine monophosphate (cGMP) with …
Formula:
C31H29N5O7
Purity:
100% - 98.42%
Color and Shape:
Soild
Molecular weight:
583.59
Ref: TM-T23411L
| 1mg | 185.00 € | ||
| 5mg | 459.00 € | ||
| 10mg | 657.00 € | ||
| 25mg | 1,026.00 € | ||
| 50mg | 1,415.00 € | ||
| 100mg | 1,872.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
Arofylline
CAS:136145-07-8
Arofylline (LAS 31025) is a PDE4 inhibitor and can be used for asthma studies.
Formula:
C14H13ClN4O2
Purity:
97.98%
Color and Shape:
Liquid
Molecular weight:
304.73
Ref: TM-T9816
| 1mg | 185.00 € | ||
| 5mg | 415.00 € | ||
| 10mg | 613.00 € | ||
| 25mg | 938.00 € | ||
| 50mg | 1,311.00 € | ||
| 1mL*10mM (DMSO) | 409.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
Dazonone
CAS:105622-85-3
Dazonone (Imidazo[2,1-b]quinazolin-2(3H)-one, 6-chloro-1,5-dihydro-3-methyl-) is a specific PDE III inhibitors.
Formula:
C11H10ClN3O
Purity:
99.21% - 99.67%
Color and Shape:
Liquid
Molecular weight:
235.67
Ref: TM-T9871
| 1mg | 77.00 € | ||
| 5mg | 158.00 € | ||
| 10mg | 225.00 € | ||
| 25mg | 338.00 € | ||
| 50mg | 475.00 € | ||
| 100mg | 638.00 € | ||
| 200mg | 845.00 € | ||
| 1mL*10mM (DMSO) | 138.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
ALDH7A1 Protein, Human, Recombinant (His)
ALDH7A1 (Aldehyde dehydrogenase 7 family, member A1) is a member of subfamily 7 in the …
Color and Shape:
Liquid
Molecular weight:
56 kDa (predicted); 56 kDa (reducing conditions)
Ref: TM-TMPY-01588
| 50µg | 608.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
