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PDE

PDE

Phosphodiesterases (PDEs) are enzymes that hydrolyze cyclic nucleotides, such as cAMP and cGMP, into their inactive forms, playing a key role in regulating intracellular signaling pathways. PDE inhibitors are used in the treatment of various conditions, including cardiovascular diseases, erectile dysfunction, and respiratory disorders, due to their ability to modulate cyclic nucleotide levels. At CymitQuimica, we provide a range of PDE inhibitors to support your research in cell signaling, pharmacology, and therapeutic development.

Found 165 products of "PDE"

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  • PF-05180999
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    PF-05180999

    CAS:
    <p>α-2,3-sialyltransferase-IN-1 (Lith-O-Asp analog) is an α-2,3-sialyltransferase inhibitor with anticancer activity.</p>
    Formula:C19H17F3N8
    Purity:99.43% - 99.82%
    Color and Shape:Solid
    Molecular weight:414.39

    Ref: TM-T16484

  • ENPP1 Inhibitor C
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    ENPP1 Inhibitor C

    CAS:
    <p>ML-354 (VU0099704) is an antagonist with and PAR4 for the study of cardiovascular diseases.</p>
    Formula:C15H18N6
    Purity:99.28%
    Color and Shape:Solid
    Molecular weight:282.34

    Ref: TM-T37431

  • PF-05085727
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    PF-05085727

    CAS:
    <p>PF-05085727 inhibits PDE2A &gt;4,000-fold selectivity over PDE1 and PDE3-11.</p>
    Formula:C20H18F3N7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:413.4

    Ref: TM-T16482

  • CymitQuimica logo
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    Anti-ALDH7A1 Antibody (3P955)

    <p>Anti-ALDH7A1 Antibody (3P955) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (3P955) can be used in WB,ELISA,IP.</p>
    Color and Shape:Odour Liquid

    Ref: TM-TMAY-01934

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    Anti-ALDH7A1 Antibody-FITC (5P692)

    <p>Anti-ALDH7A1 Antibody-FITC (5P692) is a FITC-conjugated Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody-FITC (5P692) can be used in FCM.</p>
    Color and Shape:Odour Liquid

    Ref: TM-TMAY-01933F

  • CymitQuimica logo
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    Anti-ALDH7A1 Antibody (6G475)

    <p>Anti-ALDH7A1 Antibody (6G475) is a Mouse antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (6G475) can be used in IHC-P.</p>
    Color and Shape:Odour Liquid

    Ref: TM-TMAY-01932

  • BAY 73-6691 racemate
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    BAY 73-6691 racemate

    CAS:
    <p>BAY 73-6691 racemate (Rac-BAY 73-6691) is a phosphodiesterase 9A (PDE9A) inhibitor, useful for studying Parkinson’s disease.</p>
    Formula:C15H12ClF3N4O
    Color and Shape:Solid
    Molecular weight:356.73

    Ref: TM-T10481

  • Autotaxin modulator 1
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    Autotaxin modulator 1

    CAS:
    <p>Autotaxin modulator 1 is a new modulator of Autotaxin.</p>
    Formula:C28H31F6NO3
    Purity:99.46%
    Color and Shape:Solid
    Molecular weight:543.54

    Ref: TM-T10418

  • Z-HA155
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    Z-HA155

    CAS:
    <p>Z-HA155 (CS-963) selectively and potently inhibits autotaxin with an IC50 of 5.7 nM.</p>
    Formula:C24H19BFNO5S
    Purity:99.18%
    Color and Shape:Solid
    Molecular weight:463.29

    Ref: TM-T11533

  • PQ-10
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    PQ-10

    CAS:
    <p>PQ-10 (A-844337) is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.</p>
    Formula:C22H21N5O3
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:403.43

    Ref: TM-T24656

  • Crisaborole
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    Crisaborole

    CAS:
    <p>Crisaborole (AN-2728) is a Phosphodiesterase 4 Inhibitor.</p>
    Formula:C14H10BNO3
    Purity:99.70%
    Color and Shape:Solid
    Molecular weight:251.05

    Ref: TM-T4285

  • Udenafil
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    Udenafil

    CAS:
    <p>Udenafil is an inhibitor of PDE5 .</p>
    Formula:C25H36N6O4S
    Purity:99.90%
    Color and Shape:Off-White Solid
    Molecular weight:516.66

    Ref: TM-T17199

  • HA 155
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    HA 155

    CAS:
    <p>HA 155 (Autotaxin Inhibitor IV) is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.</p>
    Formula:C24H19BFNO5S
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:463.29

    Ref: TM-T22086

  • PF-8380
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    PF-8380

    CAS:
    <p>PF-8380 is an effective and orally available autotaxin inhibitor (IC50: 2.8 nM, in isolated enzyme assay; 101 nM, in the human whole blood).</p>
    Formula:C22H21Cl2N3O5
    Purity:98.70% - 99.25%
    Color and Shape:Solid
    Molecular weight:478.33

    Ref: TM-T3631

  • IBMX
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    IBMX

    CAS:
    <p>IBMX (Methylisobutylxanthine) is a broad-spectrum phosphodiesterase (PDE) inhibitor with inhibitory activity against PDE3, PDE4, and PDE5 (IC50=6.5/26.3/31.7 μM</p>
    Formula:C10H14N4O2
    Purity:98% - >99.99%
    Color and Shape:Off-White
    Molecular weight:222.24

    Ref: TM-T1713

  • Ibudilast
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    Ibudilast

    CAS:
    <p>Ibudilast (MN-166)(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor. It is approved for use as an anti-inflammatory in Japan.</p>
    Formula:C14H18N2O
    Purity:99.83% - >99.99%
    Color and Shape:White Solid
    Molecular weight:230.31

    Ref: TM-T2137

  • RS-25344 hydrochloride
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    RS-25344 hydrochloride

    CAS:
    <p>RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitor</p>
    Formula:C19H14ClN5O4
    Purity:99.25%
    Color and Shape:Solid
    Molecular weight:411.8

    Ref: TM-T23256

  • SEP-0372814
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    SEP-0372814

    CAS:
    <p>SEP-0372814 is a potent inhibitor of PDE10.</p>
    Formula:C21H19N7
    Purity:99.29%
    Color and Shape:Solid
    Molecular weight:369.42

    Ref: TM-T8454

  • ML-030
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    ML-030

    CAS:
    <p>ML-030 is a potent PDE4 inhibitor, selective for subtypes (A1, B1, B2, C1, D2) with IC50 ranging from 6.7 to 452 nM.</p>
    Formula:C20H20N4O4S
    Purity:97.93%
    Color and Shape:Solid
    Molecular weight:412.46

    Ref: TM-T5496

  • BRL-50481
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    BRL-50481

    CAS:
    <p>BRL-50481 is a novel and selective inhibitor of PDE7 with IC50s of 0.15, 12.1, 62 and 490 μM for PDE7A, PDE7B, PDE4 and PDE3, respectively.</p>
    Formula:C9H12N2O4S
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:244.27

    Ref: TM-T5106