Glucokinase
Glucokinase (GK) is an enzyme that catalyzes the phosphorylation of glucose to glucose-6-phosphate, a critical step in glycolysis. GK is predominantly expressed in the liver and pancreas, where it plays a key role in regulating blood glucose levels. Inhibitors of GK are of interest in the study of metabolic disorders such as diabetes, as they can modulate glucose metabolism and insulin secretion. At CymitQuimica, we provide glucokinase inhibitors to support your research in diabetes, metabolism, and therapeutic development.
Found 53 products of "Glucokinase"
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Dorzagliatin
CAS:<p>Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.</p>Formula:C22H27ClN4O5Purity:98.67% - 99.45%Color and Shape:SolidMolecular weight:462.93MitoPQ
CAS:<p>MitoPQ (MitoParaquat) inhibits insulin-stimulated glucose uptake and plasma membrane translocation in myotubes and can be used to study oxidative stress.</p>Formula:C39H46I3N2PPurity:99.91% - ≥98%Color and Shape:SolidMolecular weight:954.48WAY-640509
CAS:<p>WAY-640509 is a glucocerebrosidase inhibitor.</p>Formula:C25H23N5O4SPurity:99.36%Color and Shape:SolidMolecular weight:489.55MK-0941 free base
CAS:<p>MK-0941: an oral glucokinase activator for type 2 diabetes with potent glucose-lowering effects.</p>Formula:C21H24N4O6SPurity:98.75%Color and Shape:SolidMolecular weight:460.5Oxfendazole
CAS:<p>Oxfendazole (RS-8858), a broad spectrum benzimidazole anthelmintic, protects livestock against roundworm, strongyles and pinworms.</p>Formula:C15H13N3O3SPurity:98.99% - 99.17%Color and Shape:White To Yellowish PowderMolecular weight:315.35KAN0438757
CAS:<p>KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.</p>Formula:C21H18FNO7SPurity:99.34%Color and Shape:SolidMolecular weight:447.43ADP-specific glucokinase
CAS:<p>ADP-specific glucokinase, expressed in thermophilic archaea, is an ADP-specific enzyme that catalyzes the conversion of glucose to glucose-6-phosphate, thereby facilitating glycolysis. This enzyme can activate T cells and enhance the phagocytic activity of macrophages. It is used in research related to metabolic disorders, neurological diseases, and tumors.</p>Color and Shape:Solid(1S,2R)-Globalagliatin
CAS:<p>(1S,2R)-Globalagliatin is a highly potent glucokinase (GK) activator for the study of type 2 diabetes.</p>Formula:C28H37N3O3S3Purity:99.09% - >99.99%Color and Shape:SoildMolecular weight:559.81ML266
CAS:<p>ML266: GCase chaperone, non-inhibiting, IC50=2.5 µM, aids mutant protein transport, may help in Gaucher disease study.</p>Formula:C24H22BrN3O4Purity:99.58%Color and Shape:SolidMolecular weight:496.35ML251
CAS:<p>ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.</p>Formula:C17H13Cl2N3O4SPurity:99.87%Color and Shape:SolidMolecular weight:426.27AP-III-a4 hydrochloride
CAS:<p>AP-III-a4 hydrochloride (ENOblock hydrochloride) is a direct enolase (enolase) inhibitor that inhibit metastasis and affect glucose homeostasis.</p>Formula:C31H44ClFN8O3Purity:98%Color and Shape:SolidMolecular weight:631.18Glucokinase Protein, Human, Recombinant
<p>Glucokinase belongs to the bacterial glucokinase family.</p>Color and Shape:Lyophilized PowderMolecular weight:52.2 kDa (predicted); 52.2 kDa (reducing conditions)Cadisegliatin
CAS:<p>Cadisegliatin (TTP-399) may activate liver GK to lower blood sugar in type 2 diabetes studies.</p>Formula:C21H33N3O4S2Color and Shape:SolidMolecular weight:455.63Anti-Glucokinase Antibody (5Q209)
<p>Anti-Glucokinase Antibody (5Q209) is a Mouse antibody targeting Glucokinase. Anti-Glucokinase Antibody (5Q209) can be used in ELISA.</p>Color and Shape:Odour LiquidAnti-Glucokinase Antibody (3U461)
<p>Anti-Glucokinase Antibody (3U461) is a Rabbit antibody targeting Glucokinase. Anti-Glucokinase Antibody (3U461) can be used in ELISA.</p>Color and Shape:Odour Liquid5MPN
CAS:<p>5MPN is a PFKFB4 inhibitor that inhibits the F6P binding site and suppresses the proliferation of myeloma cells.</p>Formula:C15H19N3O4Purity:98.92% - 99.69%Color and Shape:SolidMolecular weight:305.33PF-04991532
CAS:<p>PF-04991532 is a hepatoselective glucokinase activator that reduces plasma glucose and AMP concentrations in the Goto-Kakizaki rat model.</p>Formula:C18H19F3N4O3Purity:99.99%Color and Shape:SolidMolecular weight:396.36PFK-015
CAS:<p>PFK-015 (PFK15) is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).</p>Formula:C17H12N2OPurity:99.7% - 99.85%Color and Shape:SolidMolecular weight:260.29Globalagliatin
CAS:<p>Globalagliatin (LY2608204) has been used in trials studying the treatment of Diabetes Mellitus, Type 2.</p>Formula:C28H37N3O3S3Purity:98% - 99.49%Color and Shape:SolidMolecular weight:559.81(E)-3PO
CAS:<p>(E)-3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase) inhibitor.</p>Formula:C13H10N2OPurity:98.8% - 98.92%Color and Shape:SolidMolecular weight:210.23
