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Glucokinase

Glucokinase

Glucokinase (GK) is an enzyme that catalyzes the phosphorylation of glucose to glucose-6-phosphate, a critical step in glycolysis. GK is predominantly expressed in the liver and pancreas, where it plays a key role in regulating blood glucose levels. Inhibitors of GK are of interest in the study of metabolic disorders such as diabetes, as they can modulate glucose metabolism and insulin secretion. At CymitQuimica, we provide glucokinase inhibitors to support your research in diabetes, metabolism, and therapeutic development.

Found 55 products for "Glucokinase".

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  • AM-2394
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    AM-2394

    CAS:
    AM-2394 is an effective and specific Glucokinase agonist (GKA, EC50: 60 nM), which catalyzes the phosphorylation of glucose to glucose-6-phosphate.
    Formula:C22H25N5O4
    Purity:99.01% - 99.62%
    Color and Shape:Solid
    Molecular weight:423.465

    Ref: TM-T3312

  • (E)-3PO
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    (E)-3PO

    CAS:
    (E)-3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase) inhibitor.
    Formula:C13H10N2O
    Purity:98.8% - 98.92%
    Color and Shape:Solid
    Molecular weight:210.23

    Ref: TM-T3260

  • AMG-3969
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    AMG-3969

    CAS:
    AMG-3969 is an effective glucokinase-glucokinase regulatory protein interaction (GK-GKRP) disruptor (IC50: 4 nM).
    Formula:C21H20F6N4O3S
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:522.464

    Ref: TM-TQ0055

  • Globalagliatin
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    Globalagliatin

    CAS:
    Globalagliatin (LY2608204) has been used in trials studying the treatment of Diabetes Mellitus, Type 2.
    Formula:C28H37N3O3S3
    Purity:96.61% - 99.56%
    Color and Shape:Solid
    Molecular weight:559.807

    Ref: TM-T3104

  • ML198
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    ML198

    CAS:
    ML198: Activates & chaperones glucocerebrosidase; a potential Gaucher disease treatment lead.
    Formula:C17H14N4O
    Purity:98.54%
    Color and Shape:Orange Solid
    Molecular weight:290.3193

    Ref: TM-T8986

  • Genz-123346 free base
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    Genz-123346 free base

    CAS:
    Genz 123346 is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1.
    Formula:C24H38N2O4
    Purity:99.41%
    Color and Shape:Solid
    Molecular weight:418.5695

    Ref: TM-T4049

  • Palmitelaidic Acid
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    Palmitelaidic Acid

    CAS:
    Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.
    Formula:C16H30O2
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:254.4082

    Ref: TM-T19500

  • WAY-615145
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    WAY-615145

    CAS:
    WAY-615145 is a compound that activates glucokinase.
    Formula:C16H18N2OS
    Color and Shape:Solid
    Molecular weight:286.392

    Ref: TM-T202189

  • GKA-22
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    GKA-22

    CAS:
    GKA-22 is a human glucokinase allosteric activator in the absence of glucose.
    Formula:C22H22N2O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:426.49

    Ref: TM-T25451

  • YZ9
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    YZ9

    CAS:
    Y29 is a potent PFKFB3 inhibitor with an IC50 of 0.183 µM, and acts as a competitive inhibitor against Fru-6-P with a Ki of 0.094 µM[1].
    Formula:C12H10O5
    Purity:99.59%
    Color and Shape:Solid
    Molecular weight:234.2048

    Ref: TM-T23552

  • Piragliatin
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    Piragliatin

    CAS:
    Piragliatin (RO4389620) activates glucokinase, boosts insulin, and lowers glucose in type 2 diabetes.
    Formula:C19H20ClN3O4S
    Color and Shape:Solid
    Molecular weight:421.9

    Ref: TM-T68976

  • Glucokinase activator 1
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    Glucokinase activator 1

    CAS:
    Glucokinase activator 1 is a liver-directed glucokinase activator (EC50: 34 nM).
    Formula:C27H20F2N2O7S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:586.58

    Ref: TM-T11418

  • IHVR-11029
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    IHVR-11029

    CAS:
    IHVR-11029 inhibits ER α-glucosidase, combats hemorrhagic fever viruses, and hinders enveloped virus morphogenesis.
    Formula:C18H27F2NO5
    Color and Shape:Solid
    Molecular weight:375.4075

    Ref: TM-T27590

  • GKA-71
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    GKA-71

    CAS:
    GKA-71 is an effective glucokinase activator (GKA).
    Formula:C21H23N3O6S2
    Color and Shape:Solid
    Molecular weight:477.55

    Ref: TM-T25452

  • Glucokinase activator 3
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    Glucokinase activator 3

    CAS:
    Glucokinase activator 3: potent GK activator, AC50=38 nM, potential for type 2 diabetes research.
    Formula:C26H33N2O9PS2
    Color and Shape:Solid
    Molecular weight:612.65

    Ref: TM-T72284

  • PF-04279405
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    PF-04279405

    CAS:
    PF-04279405 is a potent and selective glucokinase activator.
    Formula:C25H25FN4O4
    Color and Shape:Solid
    Molecular weight:464.49

    Ref: TM-T68244

  • Sinogliatin
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    Sinogliatin

    CAS:
    Sinogliatin, a glucokinase activator, is used potentially for the treatment of type 2 diabetes.
    Formula:C22H27ClN4O5
    Color and Shape:Solid
    Molecular weight:462.93

    Ref: TM-T28781

  • (R)-PF-04991532
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    (R)-PF-04991532

    (R)-PF-04991532 is the R-enantiomer of PF-04991532 . PF-04991532 is a potent, hepatoselective glucokinase activator .
    Formula:C18H19F3N4O3
    Color and Shape:Solid
    Molecular weight:396.36

    Ref: TM-T72743

  • Cefetrizole
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    Cefetrizole

    CAS:
    Ceftezole is an α-Glucosidase inhibitor (IC50: 2.1 μM; Ki: 0.578 μM).
    Formula:C16H15N5O4S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:437.52

    Ref: TM-T10751

  • PSN-GK1
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    PSN-GK1

    CAS:
    PSN-GK1 is a potent activator of glucokinase (EC50: 0.13 μM).
    Formula:C20H23FN2O4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:438.54

    Ref: TM-T10092