Glucokinase
Glucokinase (GK) is an enzyme that catalyzes the phosphorylation of glucose to glucose-6-phosphate, a critical step in glycolysis. GK is predominantly expressed in the liver and pancreas, where it plays a key role in regulating blood glucose levels. Inhibitors of GK are of interest in the study of metabolic disorders such as diabetes, as they can modulate glucose metabolism and insulin secretion. At CymitQuimica, we provide glucokinase inhibitors to support your research in diabetes, metabolism, and therapeutic development.
Found 56 products of "Glucokinase"
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(E)-3PO
CAS:(E)-3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase) inhibitor.Formula:C13H10N2OPurity:98.8% - 98.92%Color and Shape:SolidMolecular weight:210.23AMG-3969
CAS:AMG-3969 is an effective glucokinase-glucokinase regulatory protein interaction (GK-GKRP) disruptor (IC50: 4 nM).Formula:C21H20F6N4O3SPurity:99.65%Color and Shape:SolidMolecular weight:522.46Ref: TM-TQ0055
1mg52.00€5mg111.00€1mL*10mM (DMSO)131.00€10mg172.00€25mg289.00€50mg399.00€100mg532.00€200mg740.00€Globalagliatin
CAS:Globalagliatin (LY2608204) has been used in trials studying the treatment of Diabetes Mellitus, Type 2.Formula:C28H37N3O3S3Purity:98% - 99.56%Color and Shape:SolidMolecular weight:559.81Genz-123346 free base
CAS:Genz 123346 is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1.Formula:C24H38N2O4Purity:99.41%Color and Shape:SolidMolecular weight:418.57AM-2394
CAS:AM-2394 is an effective and specific Glucokinase agonist (GKA, EC50: 60 nM), which catalyzes the phosphorylation of glucose to glucose-6-phosphate.Formula:C22H25N5O4Purity:99.01% - 99.62%Color and Shape:SolidMolecular weight:423.46Ref: TM-T3312
2mg34.00€5mg49.00€1mL*10mM (DMSO)50.00€10mg66.00€25mg105.00€50mg172.00€100mg264.00€200mg394.00€3PO
CAS:3PO inhibits PFKFB3 (IC50: 22.9 µM) and cancer cell growth (IC50: 1.4-24 µM), reducing glucose uptake and key cellular metabolites.
Formula:C13H10N2OPurity:99.56% - 99.67%Color and Shape:SolidMolecular weight:210.23Palmitelaidic Acid
CAS:Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.Formula:C16H30O2Purity:99.76%Color and Shape:SolidMolecular weight:254.41ML198
CAS:ML198: Activates & chaperones glucocerebrosidase; a potential Gaucher disease treatment lead.Formula:C17H14N4OPurity:98.31%Color and Shape:SolidMolecular weight:290.32Ref: TM-T8986
2mg46.00€1mL*10mM (DMSO)80.00€5mg92.00€10mg124.00€25mg241.00€50mg360.00€100mg537.00€200mg710.00€YZ9
CAS:Y29 is a potent PFKFB3 inhibitor with an IC50 of 0.183 µM, and acts as a competitive inhibitor against Fru-6-P with a Ki of 0.094 µM[1].Formula:C12H10O5Purity:99.59%Color and Shape:SolidMolecular weight:234.2Piragliatin
CAS:Piragliatin (RO4389620) activates glucokinase, boosts insulin, and lowers glucose in type 2 diabetes.Formula:C19H20ClN3O4SColor and Shape:SolidMolecular weight:421.9Glucokinase activator 1
CAS:Glucokinase activator 1 is a liver-directed glucokinase activator (EC50: 34 nM).Formula:C27H20F2N2O7S2Purity:98%Color and Shape:SolidMolecular weight:586.58IHVR-11029
CAS:IHVR-11029 inhibits ER α-glucosidase, combats hemorrhagic fever viruses, and hinders enveloped virus morphogenesis.Formula:C18H27F2NO5Color and Shape:SolidMolecular weight:375.41GKA-71
CAS:GKA-71 is an effective glucokinase activator (GKA).Formula:C21H23N3O6S2Color and Shape:SolidMolecular weight:477.55Glucokinase activator 3
CAS:Glucokinase activator 3: potent GK activator, AC50=38 nM, potential for type 2 diabetes research.Formula:C26H33N2O9PS2Color and Shape:SolidMolecular weight:612.65PF-04279405
CAS:PF-04279405 is a potent and selective glucokinase activator.Formula:C25H25FN4O4Color and Shape:SolidMolecular weight:464.49PSN-GK1
CAS:PSN-GK1 is a potent activator of glucokinase (EC50: 0.13 μM).Formula:C20H23FN2O4S2Purity:98%Color and Shape:SolidMolecular weight:438.54Sinogliatin
CAS:Sinogliatin, a glucokinase activator, is used potentially for the treatment of type 2 diabetes.Formula:C22H27ClN4O5Color and Shape:SolidMolecular weight:462.93(R)-PF-04991532
(R)-PF-04991532 is the R-enantiomer of PF-04991532 . PF-04991532 is a potent, hepatoselective glucokinase activator .Formula:C18H19F3N4O3Color and Shape:SolidMolecular weight:396.36Cefetrizole
CAS:Ceftezole is an α-Glucosidase inhibitor (IC50: 2.1 μM; Ki: 0.578 μM).Formula:C16H15N5O4S3Purity:98%Color and Shape:SolidMolecular weight:437.52RO-28-1675
CAS:RO-28-1675 is a direct and selective glucokinase activator, the GK/GKRP complex,insulin secretion and type 2 diabetes.Formula:C18H22N2O3S2Purity:98.13%Color and Shape:SolidMolecular weight:378.51Ref: TM-T16793
1mg59.00€5mg126.00€1mL*10mM (DMSO)138.00€10mg191.00€25mg386.00€50mg623.00€100mg947.00€200mg1,324.00€
