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Glucokinase

Glucokinase

Glucokinase (GK) is an enzyme that catalyzes the phosphorylation of glucose to glucose-6-phosphate, a critical step in glycolysis. GK is predominantly expressed in the liver and pancreas, where it plays a key role in regulating blood glucose levels. Inhibitors of GK are of interest in the study of metabolic disorders such as diabetes, as they can modulate glucose metabolism and insulin secretion. At CymitQuimica, we provide glucokinase inhibitors to support your research in diabetes, metabolism, and therapeutic development.

Found 53 products of "Glucokinase"

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  • AR453588 hydrochloride
    Targetmol
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    AR453588 hydrochloride

    CAS:
    <p>AR453588 hydrochloride is an orally bioavailable anti-diabetic glucokinase activator (EC50: 42 nM) with anti-hyperglycemic activity.</p>
    Formula:C25H26ClN7O2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:556.1

    Ref: TM-T10362L

  • CM-10-18
    Targetmol
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    CM-10-18

    CAS:
    <p>CM-10-18: potent ER α-glucosidase inhibitor, strong antiviral against hemorrhagic fever viruses, protects mice from dengue fatality.</p>
    Formula:C17H35NO5
    Color and Shape:Solid
    Molecular weight:333.46

    Ref: TM-T27050

  • PF-04937319
    Targetmol
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    PF-04937319

    CAS:
    <p>PF-04937319 activates glucokinase (EC50=154.4μM) with low hypoglycemia risk, researched for type 2 diabetes treatment.</p>
    Formula:C22H20N6O4
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:432.43

    Ref: TM-T16479

  • AZD-1656
    Targetmol
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    AZD-1656

    CAS:
    <p>AZD-1656 is a glucokinase activator (GKA) that can cause dose-limiting hypoglycemia in normal animals used in embryofetal development studies and type 2</p>
    Formula:C24H26N6O5
    Purity:97.07% - 99.37%
    Color and Shape:Solid
    Molecular weight:478.5

    Ref: TM-T26712

  • AZD1092
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    AZD1092

    CAS:
    <p>AZD1092 is the glucokinase enzyme activator.</p>
    Formula:C24H26N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:450.49

    Ref: TM-T23765

  • WAY-297848
    Targetmol
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    WAY-297848

    CAS:
    <p>WAY-297848 is a novel glucokinase activator for the prevention or treatment of hyperglycemia, diabetes mellitus, obesity, dyslipidemia, and metabolic syndrome.</p>
    Formula:C13H13ClN2O2S
    Purity:98.19%
    Color and Shape:Solid
    Molecular weight:296.77

    Ref: TM-T77784

  • Glucokinase activator 7
    Targetmol
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    Glucokinase activator 7

    CAS:
    <p>Glucokinase activator7 is an activator of glucose kinase (Glucokinase) and can be utilized in research on diabetes and hyperglycemia [refer to compound on page 176].</p>
    Formula:C14H13N3O2S
    Color and Shape:Solid
    Molecular weight:287.337

    Ref: TM-T205646

  • CymitQuimica logo
    Targetmol
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    GKA50 quarterhydrate

    <p>GKA50 quarterhydrate: glucokinase activator, EC50 of 33 nM, boosts insulin, cuts glucose in rats.</p>
    Formula:C26H30N2O7
    Color and Shape:Solid
    Molecular weight:469.01

    Ref: TM-T63019

  • Gcase activator 2
    Targetmol
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    Gcase activator 2

    CAS:
    <p>Gcase activator 2 is a β-glucocerebrosidase activator that induces dimerization of GCase, increases lysosomal substrate metabolism.</p>
    Formula:C21H24N4O2
    Purity:99.51% - 99.76%
    Color and Shape:Solid
    Molecular weight:364.44

    Ref: TM-T86495

  • Glucokinase activator 8
    Targetmol
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    Glucokinase activator 8

    CAS:
    <p>Glucokinase activator8 is an activator of glucose kinase (glucokinase).</p>
    Formula:C14H13N3O2S
    Color and Shape:Solid
    Molecular weight:287.337

    Ref: TM-T205380

  • MK-0941
    Targetmol
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    MK-0941

    CAS:
    <p>MK-0941 is an orally active and allosteric glucokinase activator, has potential in the treatment of type 2 diabetes.</p>
    Formula:C22H28N4O9S2
    Color and Shape:Solid
    Molecular weight:556.61

    Ref: TM-T12057

    1mg
    Discontinued
    Discontinued product
  • Hex
    Targetmol
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    Hex

    CAS:
    <p>Hex is a potent inhibitor of enolase, exhibiting inhibitory activity with Ki values of 74.4 nM and 269.4 nM against ENO2 and ENO1, respectively.</p>
    Formula:C5H10NO5P
    Color and Shape:Solid
    Molecular weight:195.11

    Ref: TM-T39419

    ne
    Discontinued
    Discontinued product
  • GKA50
    Targetmol
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    GKA50

    CAS:
    <p>GKA50 stimulates insulin release from mouse islets of Langerhans and MIN6 cells. GKA50 shows significant glucose lowering in high fat fed female rats. GKA50 is a potent glucokinase activator (EC50=33 nM at 5 mM glucose).</p>
    Formula:C26H28N2O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:464.51

    Ref: TM-T11401

    50mg
    Discontinued
    100mg
    Discontinued
    Discontinued product