SGK
Serum and Glucocorticoid-Regulated Kinase (SGK) is a protein kinase involved in the regulation of various cellular processes, including ion transport, cell survival, and glucose metabolism. SGK inhibitors are valuable in the study of conditions such as hypertension, diabetes, and cancer, where SGK activity plays a crucial role. These inhibitors help in understanding the signaling pathways regulated by SGK and their implications in disease. At CymitQuimica, we offer SGK inhibitors to support your research in signal transduction, metabolic diseases, and cancer therapy.
Found 11 products for "SGK".
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SGK1-IN-3 hydrochloride
SGK1-IN-3 hydrochloride is an oral SGK1 inhibitor that blocks 尾-catenin activation and shows potential in osteoarthritis.Formula:C23H21Cl3N6O3SColor and Shape:SolidMolecular weight:567.88308-R-C4-PEG3-C1-Boc
CAS:308-R-C4-PEG3-C1-Boc is an SGK3 ligand-linker conjugate, utilized in the synthesis of PROTAC SGK3 degrader-2.Formula:C39H53FN6O9SColor and Shape:SolidMolecular weight:800.94SGK1-IN-4
CAS:SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.Formula:C23H21ClFN5O4SPurity:97.03%Color and Shape:SolidMolecular weight:517.96Ref: TM-T9977
1mg105.00€5mg250.00€1mL*10mM (DMSO)301.00€10mg356.00€25mg580.00€50mg781.00€100mg1,044.00€200mg1,404.00€SI-113
CAS:SI-113 is a potent and selective inhibitor of SGK1, a serine/threonine protein kinase, that modulates several oncogenic signaling cascades.Formula:C23H24N6OPurity:98.93%Color and Shape:SolidMolecular weight:400.4763Ref: TM-T9589
1mg43.00€2mg55.00€5mg92.00€1mL*10mM (DMSO)101.00€10mg133.00€25mg236.00€50mg353.00€100mg518.00€CKI-7
CAS:CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.Formula:C11H14Cl3N3O2SPurity:>99.99%Color and Shape:SolidMolecular weight:358.67GSK 650394
CAS:GSK 650394 is an inhibitor of serum- and glucocorticoid-regulated kinases (SGK). GSK 650394 has antitumor activity. Cost-effective and quality-assured.Formula:C25H22N2O2Purity:97.46% - >99.99%Color and Shape:White SolidMolecular weight:382.45Ref: TM-T2622
1mg38.00€2mg54.00€5mg83.00€1mL*10mM (DMSO)92.00€10mg105.00€25mg197.00€50mg312.00€100mg446.00€200mg623.00€EMD638683
CAS:EMD638683,a novel SGK inhibitor with antihypertensive potency(with an IC50 of 3 μM).Formula:C18H18F2N2O4Purity:98%Color and Shape:White SolidMolecular weight:364.3433Ref: TM-T6635
1mg73.00€2mg101.00€1mL*10mM (DMSO)120.00€5mg150.00€10mg232.00€25mg357.00€50mg517.00€100mg737.00€200mg981.00€SGK1-IN-1
CAS:SGK1-IN-1 (compound 14n) is a highly potent SGK1 (Serum/Glucocorticoid Regulated Kinase 1) inhibitorFormula:C17H12ClFN6O2SPurity:97.44%Color and Shape:SolidMolecular weight:418.833Ref: TM-T12890
1mg103.00€5mg222.00€1mL*10mM (DMSO)244.00€10mg356.00€25mg708.00€50mg1,071.00€100mg1,467.00€EMD638683 R-Form
CAS:EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM. EMD638683 R-Form is the R-form of EMD638683.Formula:C18H18F2N2O4Color and Shape:SolidMolecular weight:364.3433SGK1-IN-8
CAS:SGK1-IN-8 (compound 55) is an inhibitor of SGK1 and GSK3β, exhibiting an IC50 of 0.11 μM for human SGK1 and 3.39 μM for human GSK3β. It reduces the catalytic activity of both SGK1 and GSK3β and decreases the phosphorylation level of TAU protein at the Ser214 site. SGK1-IN-8 is applicable in Alzheimer's disease research.Formula:C18H13ClN4OMolecular weight:336.78SGK1-IN-6
CAS:SGK1-IN-6 (compound 12f) is an SGK1 inhibitor with an IC50 value of 0.39 μM. In PC3 xenograft models using BALB/c nude mice, SGK1-IN-6 effectively hinders tumor growth without causing any observable toxicity.Formula:C30H30F3N5O4Color and Shape:SolidMolecular weight:581.586
