Aminopeptidase
Aminopeptidases are a group of enzymes that catalyze the cleavage of amino acids from the N-terminus of peptides and proteins, playing a crucial role in protein maturation and degradation. These enzymes are involved in various physiological processes, including antigen processing, peptide hormone regulation, and cellular homeostasis. Inhibitors of aminopeptidases are of interest in the treatment of diseases such as cancer, inflammation, and infectious diseases. At CymitQuimica, we provide a variety of aminopeptidase inhibitors to support your research in proteomics, drug development, and disease treatment.
Found 67 products of "Aminopeptidase"
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ERAP1-IN-1
CAS:<p>ERAP1-IN-1 inhibits and allosterically activates ERAP1, affecting fluorogenic, chromogenic, and nonamer peptide substrates.</p>Formula:C20H21F3N2O5SPurity:98.95%Color and Shape:SolidMolecular weight:458.45Bufexamac
CAS:<p>Bufexamac (Bufexamic acid) is a COX inhibitor for IFN-α release with anti-inflammatory, analgesic, and antipyretic action.</p>Formula:C12H17NO3Purity:99.73%Color and Shape:Acicular CrystalMolecular weight:223.27Probestin
CAS:<p>Probestin is an aminopeptidase M inhibitor, isolated from Streptomyces azureus MH663-2F6.</p>Formula:C26H38N4O6Purity:98%Color and Shape:SolidMolecular weight:502.60Aminopeptidase N inhibitor 2
<p>AminopeptidaseN inhibitor 2 is an APN inhibitor (IC50: 4.3 μM) with antitumor properties.</p>Formula:C12H16F2N2O4SColor and Shape:SolidMolecular weight:322.07988BAY-277
<p>BAY-277 is a degrader of METAP2, with IC50 values of 5.8 nM for human METAP2 (hMETAP2) and 5.9 nM for mouse METAP2 (mMETAP2).</p>Formula:C44H52N8O5Color and Shape:SolidMolecular weight:772.93LTA4H-IN-4
<p>LTA4H-IN-4 (compound 3) is an orally active inhibitor of LTA4H. It exhibits an IC50 value of 156 μM against hERG and is applicable for inflammation-related research.</p>Leuhistin
CAS:<p>Leuhistin is an aminopeptidases N inhibitor isolated from Bacillus laterosporus BMI156-14F1.</p>Formula:C11H19N3O3Purity:98%Color and Shape:White To Off-White SolidMolecular weight:241.29Matlystatin A
CAS:<p>Matlystatin A is an inhibitor of aminopeptidase. It shows multiple inhibitory activities against both aminopeptidase N and matrix metalloproteinases.</p>Formula:C27H47N5O8SColor and Shape:SolidMolecular weight:601.76SDUY817
<p>SDUY817 is a dual APN/NEP inhibitor with IC50 values of 0.29 μM for APN and 7.4 μM for NEP. It exhibits analgesic effects in a concentration- and time-dependent manner, making it a potential candidate for research in the field of neuropathic pain disorders.</p>Formula:C18H16IN3O3Color and Shape:SolidMolecular weight:449.24CD13-IN-1
<p>CD13-IN-1 (Compound 5f) is a CD13 inhibitor with an IC50 value of 1.71 μM. It effectively suppresses the proliferation of various tumor cells, demonstrating antitumor activity.</p>Color and Shape:Odour SolidAmastatin hydrochloride
CAS:<p>Amastatin HCl is an inhibitor of aminopeptidase. It also induces vasoconstriction.</p>Formula:C21H39ClN4O8Color and Shape:White To Off-White PowderMolecular weight:511.01ecMetAP-IN-1
CAS:<p>ecMetAP-IN-1 可用作 QSAR 模型，以使用多元线性回归研究蛋氨酸氨基肽酶抑制剂作为抗癌剂。</p>Formula:C13H11N3Purity:99.34%Color and Shape:SolidMolecular weight:209.25NGR peptide
CAS:<p>Cell-penetrating peptide</p>Formula:C20H36N10O8S2Purity:98%Color and Shape:SolidMolecular weight:608.69JNJ-40929837 succinate
CAS:<p>JNJ-40929837 succinate is a selective, orally active inhibitor of LTA 4 H (leukotriene A 4 hydrolase). This compound effectively inhibits aminopeptidase activity, leading to the accumulation of Pro-Gly-Pro in serum, and can be utilized in asthma research [1].</p>Formula:C22H24N4O2S·xC4H6O4Color and Shape:SolidBDM_92499
<p>BDM_92499 is a nanomolar, selective IRAP inhibitor with an IC50 of 3.4 nM. It also inhibits ERAP1 and ERAP2, with IC50 values of 0.46 μM and 4.2 μM, respectively.</p>Color and Shape:Odour SolidAclimostat
CAS:<p>Aclimostat (ZGN-1061) is a MetAP2 inhibitor with strong preclinical results, improving obesity-related metrics and gene expression.</p>Formula:C26H42N2O6Color and Shape:SolidMolecular weight:478.63Relzomostat
CAS:<p>Relzomostat inhibits MetAP2, with research potential for obesity and type 2 diabetes.</p>Formula:C24H36F2N2O5Color and Shape:SolidMolecular weight:470.558SDUY816
<p>SDUY816 is an orally active dual APN/NEP inhibitor, with IC50 values of 0.68 μM for APN and 6.9 μM for NEP. It exhibits analgesic properties and demonstrates good safety and pharmacokinetic profiles, having an oral bioavailability of 27% and a half-life of 4.02 hours in rats (oral, 10 mg/kg). SDUY816 is applicable for research in the field of neuropathic pain disorders.</p>Formula:C18H16IN3O3Color and Shape:SolidMolecular weight:449.24ERAP1-IN-3
<p>ERAP1-IN-3 (compound 13) is a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1), with a pIC50 value of 8.6. ERAP1-IN-3 shows potential for research in cancer immunotherapy and autoimmune disease studies.</p>Formula:C22H22N2O4SColor and Shape:SolidMolecular weight:410.49DG013A formate
<p>DG013A (formate) is a tripeptide-mimicking inhibitor of hypophosphorous acid. It exhibits IC50 values of 33 nM for ERAP1 and 11 nM for ERAP2. This compound can be utilized in research related to autoimmune diseases and cancer.</p>Formula:C27H37N4O4PCH2O2Color and Shape:SolidMolecular weight:530.99
