Casein Kinase
Casein kinases are a family of serine/threonine protein kinases that regulate various cellular processes, including DNA repair, circadian rhythms, and signal transduction. These kinases are involved in the phosphorylation of numerous proteins and are implicated in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. At CymitQuimica, we offer a selection of casein kinase inhibitors to support your research in signal transduction, cell cycle regulation, and therapeutic development.
Found 130 products of "Casein Kinase"
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Umbralisib
CAS:<p>Umbralisib (TGR 1202) is a PI3Kδ inhibitor.</p>Formula:C31H24F3N5O3Purity:99.56% - 99.56%Color and Shape:White SolidMolecular weight:571.55TBB
CAS:<p>TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).</p>Formula:C6HBr4N3Purity:98.51% - 99.45%Color and Shape:Off-White SolidMolecular weight:434.71CKI-7
CAS:<p>CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.</p>Formula:C11H14Cl3N3O2SPurity:>99.99%Color and Shape:SolidMolecular weight:358.67Umbralisib hydrochloride
CAS:<p>Umbralisib hydrochloride: PI3Kδ inhibitor; IC50=22.2 nM, EC50=24.3 nM; active vs CK1ε, EC50=6.0 μM.</p>Formula:C31H25ClF3N5O3Purity:98%Color and Shape:SolidMolecular weight:608.01MLN8054
CAS:<p>MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.</p>Formula:C25H15ClF2N4O2Purity:98.07% - 98.26%Color and Shape:SolidMolecular weight:476.86NCC007
CAS:<p>NCC007 is a novel CKIα and CKIδ dual inhibitors by structural modification of N9 and C2 position of longdaysin.</p>Formula:C22H28F3N7Purity:98.88%Color and Shape:SolidMolecular weight:447.5CK2-IN-1
CAS:<p>CK2 inhibitor</p>Formula:C14H9NO3Purity:97.28%Color and Shape:SolidMolecular weight:239.23CK1-IN-1
CAS:<p>CK1-IN-1, a CK1 inhibitor with IC50: 15nM CK1δ, 16nM CK1ε, 73nM p38σ; patent WO2015119579A1.</p>Formula:C24H15F2N3Purity:98.79%Color and Shape:SolidMolecular weight:383.39TAK-715
CAS:<p>TAK-715 is a p38 MAPK inhibitor for p38α.</p>Formula:C24H21N3OSPurity:99.83%Color and Shape:SolidMolecular weight:399.51DMAT
CAS:<p>DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM).</p>Formula:C9H7Br4N3Purity:99.48%Color and Shape:SolidMolecular weight:476.79Silmitasertib
CAS:<p>Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).</p>Formula:C19H12ClN3O2Purity:98% - 99.90%Color and Shape:SolidMolecular weight:349.77PF-670462
CAS:<p>PF-670462 is a potent (IC50 = 7.7 ± 2.2 nM) and selective (>30-fold with respect to 42 additional kinases) inhibitor of CK1ε in isolated enzyme preparations.</p>Formula:C19H22Cl2FN5Purity:99.42% - 99.72%Color and Shape:SolidMolecular weight:410.32XL413
CAS:<p>XL-413 is an oral CDC7 kinase inhibitor, potentially blocking DNA replication, mitosis, and cancer cell growth.</p>Formula:C14H12ClN3O2Purity:98.40% - >99.99%Color and Shape:SolidMolecular weight:289.72SSTC3
CAS:<p>SSTC3 is a casein kinase 1α (CK1α) activator with potential antitumor activity that inhibits WNT signaling.</p>Formula:C23H17F3N4O3S2Purity:98.65% - 99.94%Color and Shape:SolidMolecular weight:518.53AMG-548
CAS:<p>AMG-548, oral p38α inhibitor (Ki=0.5 nM), >1000x selectivity over p38γ/δ, blocks TNFα (IC50=3 nM), also inhibits Wnt/Casein kinase 1δ/ε.</p>Formula:C29H27N5OPurity:99.91%Color and Shape:SolidMolecular weight:461.56SR-1277
CAS:<p>SR-1277 is a potent, highly selective and ATP-competitive CK1δ/ε inhibitor, regulating Wee1 activity at the G2/M cell-cycle interface, and antiproliferative.</p>Formula:C21H19N9O3SColor and Shape:SolidMolecular weight:477.5CK2/PIM1-IN-1
CAS:<p>CK2/PIM1-IN-1 inhibits CK2 & PIM1 (IC50s: 3.787 & 4.327 μM), aimed for cancer research.</p>Formula:C15H9NO4S2Purity:98%Color and Shape:SolidMolecular weight:331.374,5,6,7-Tetrabromobenzimidazole
CAS:<p>4,5,6,7-Tetrabromobenzimidazole is a selective and ATP-competitive inhibitor of protein kinase CK2 [1].</p>Formula:C7H2Br4N2Color and Shape:SolidMolecular weight:433.72CK2-IN-9
CAS:<p>CK2-IN-9, a potent and selective CK2 kinase inhibitor, exhibits an inhibitory concentration (IC50) of 3 nM against its target enzyme and hampers Wnt reporter</p>Formula:C23H29N9OColor and Shape:SolidMolecular weight:447.54Quinalizarin
CAS:<p>Quinalizarin, the most selective CK2 inhibitor, is superior to CX-4945 which is the first-in-class CK2 inhibitor.</p>Formula:C14H8O6Purity:98%Color and Shape:SolidMolecular weight:272.21Tyrphostin AG 1112
CAS:<p>Tyrphostin AG 1112 is a Bcr-Abl kinase blocker. It can activate the terminal differentiation of K562 cells and the purging of Ph+ cells.</p>Formula:C15H10N6Color and Shape:SolidMolecular weight:274.28PF 4800567 hydrochloride
CAS:<p>casein kinase 1ε inhibitor</p>Formula:C17H19Cl2N5O2Purity:98%Color and Shape:SolidMolecular weight:396.27IQA
CAS:<p>IQA is a casein kinase 2 (CK2) inhibitor.</p>Formula:C17H12N2O3Color and Shape:SolidMolecular weight:292.29(R)-DRF053 dihydrochloride
CAS:<p>cdk/CK1 inhibitor,potent and ATP-competitive</p>Formula:C23H29Cl2N7OPurity:98%Color and Shape:SolidMolecular weight:490.43TMCB
CAS:<p>CK2 and ERK8 inhibitor</p>Formula:C11H9Br4N3O2Purity:98%Color and Shape:SolidMolecular weight:534.82CK2-IN-6
CAS:<p>CK2-IN-6: Potent CK2 inhibitor for cancer, inflammation, pain, and immune research.</p>Formula:C19H16ClN7O2Color and Shape:SolidMolecular weight:409.83SRPIN-803
CAS:<p>SRPIN-803 is a selective dual SRPK1 and CK2 inhibitor.</p>Formula:C14H9F3N4O3SPurity:98%Color and Shape:SolidMolecular weight:370.31Umbralisib sulfate
CAS:<p>Umbralisib sulfate, an oral dual PI3Kδ/CK1ε inhibitor (EC50: 22.2 nM/6.0 μM), targets CLL T cells for blood cancer research.</p>Formula:C31H26F3N5O7SColor and Shape:SolidMolecular weight:669.63Umbralisib tosylate
CAS:<p>Umbralisib tosylate, an oral PI3Kδ/CK1ε inhibitor (EC50: 22.2 nM/6.0 μM), shows promise for CLL research.</p>Formula:C38H32F3N5O6SColor and Shape:SolidMolecular weight:743.75BTX161
CAS:<p>BTX161: potent CKIα degrader, surpasses Lenalidomide in AML, triggers DDR + p53, stabilizes MDM2.</p>Formula:C15H16N2O3Color and Shape:SolidMolecular weight:272.3HDAC/CK2-IN-1
CAS:<p>HDAC/CK2-IN-1 (compound 38) acts as an inhibitor of HDAC1 (IC 50 = 1.46 μM), HDAC6 (IC 50 = 0.66 μM), and CK2 (IC 50 = 3.67 μM). It demonstrates promising antiproliferative effects on various cell lines, including Jurkat, MCF-7, HCT-116, and HL-60.</p>Formula:C15H18Br4N4O2Color and Shape:SolidMolecular weight:605.95CK2-IN-4
CAS:<p>CK2-IN-4 is a protein kinase (CK2) inhibitor with an IC50 value of 8.6 µM.</p>Formula:C18H11N3O4SPurity:99.72%Color and Shape:SolidMolecular weight:365.36CK2α-IN-1
CAS:<p>CK2α-IN-1 is a selective non-ATP-competitive CK2α inhibitor with an IC50 of 7.0 µM and a Ki of 1.6 µM.CK2α-IN-1 exhibits potential anticancer activity and can</p>Formula:C16H11N3O4SPurity:98%Color and Shape:SolidMolecular weight:341.34CK1-IN-2
CAS:<p>CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor p38a, and is used in DUX4 overexpression-associated diseases, such as muscular dystrophy.</p>Formula:C17H12FN3O2Purity:99.31%Color and Shape:SolidMolecular weight:309.29PI-828
CAS:<p>PI-828 (LY 294002), a PI3K inhibitor, researches PI3K function and aids stem cell differentiation into mesoderm.</p>Formula:C19H18N2O3Purity:99.95%Color and Shape:SolidMolecular weight:322.36XL413 xHCl
CAS:<p>BMS-863233 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.BMS-863233 HCl inhibited CK2 and PIM1 with IC50 values of 215</p>Formula:C14H12ClN3O2·xHClPurity:99.37% - 99.67%Color and Shape:SolidMolecular weight:326.18BioE-1115
CAS:<p>BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).</p>Formula:C19H18FN3O2Purity:97.54%Color and Shape:SolidMolecular weight:339.36Casein kinase 1δ-IN-1
CAS:<p>Casein kinase 1δ-IN-1 (WAY-643895) is an inhibitor of casein kinase 1δ (CK1δ), which inhibits CK1δ.</p>Formula:C11H7N3OSPurity:99.46%Color and Shape:SolidMolecular weight:229.26Ac-VDVAD-CHO
CAS:<p>Ac-VDVAD-CHO is an inhibitor of caspase-2 and caspase-3 (IC50: 46 nM for caspase-2 and 15 nM for caspase-3) [1].</p>Formula:C23H37N5O10Purity:98%Color and Shape:SolidMolecular weight:543.57ON 108600
CAS:<p>ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 μM and 0.007 μM for DYRK1A and DYRK1B, 0.</p>Formula:C22H14Cl2N2O6S2Purity:98%Color and Shape:SolidMolecular weight:537.39Casein kinase 1δ-IN-5
CAS:<p>Casein kinase 1δ-IN-5 is a potent and selective CK-1δ inhibitor, exhibiting an IC50 of 47 nM, and demonstrates neuroprotective and anti-inflammatory effects in</p>Formula:C16H11F3N2OSPurity:98%Color and Shape:SolidMolecular weight:336.33Casein kinase 1δ-IN-10
CAS:<p>Casein kinase 1δ-IN-10 is an inhibitor of casein kinase 1δ (CK1δ).</p>Formula:C21H17N3O3Purity:98%Color and Shape:SolidMolecular weight:359.38TID43
CAS:<p>TID43, a CK2 inhibitor, exhibits potent inhibition with an IC50 value of 0.3 μM. It is applicable in anti-angiogenic research [1].</p>Formula:C10H3I4NO4Color and Shape:SolidMolecular weight:708.755XL413 hydrochloride
CAS:<p>XL413 hydrochloride (BMS-863233 Hydrochloride) is a potent, selective and ATP competitive inhibitor of Cdc7. XL413 hydrochloride also inhibits CK2 and PIM1.</p>Formula:C14H13Cl2N3O2Purity:98.81% - 99.8%Color and Shape:SolidMolecular weight:326.18Casein kinase 1δ-IN-4
CAS:<p>"Casein kinase 1δ-IN-4 (compound 567) is a potent inhibitor of casein kinase 1δ with potential application in Alzheimer's disease research [1]."</p>Formula:C16H12N6SPurity:98%Color and Shape:SolidMolecular weight:320.37Casein Kinase II Inhibitor IV
CAS:<p>Casein kinase II inhibitor IV is an effective small molecule inducer, which can be used to induce epidermal keratinocyte differentiation.</p>Formula:C24H23N5O3Purity:99.65% - 99.75%Color and Shape:SolidMolecular weight:429.47Casein kinase 1δ-IN-13
CAS:Casein kinase1δ-IN-13 (compound 401) is an inhibitor of Casein kinase1δ. It is utilized in the research of neurodegenerative diseases.Formula:C15H13N3O2SColor and Shape:SolidMolecular weight:299.35Casein kinase 1δ-IN-28
CAS:<p>Casein kinase1δ-IN-28 (Compound 4) is an inhibitor of CK1ε, with an IC50 of 0.0146 μM. The human liver microsome metabolism rate for Casein kinase1δ-IN-28 is 52%.</p>Formula:C23H23FN6Color and Shape:SolidMolecular weight:402.467CK1δ-IN-6
CAS:<p>CK1δ-IN-6 (Compound 303) is an inhibitor of Casein kinase 1δ, with potential applications in Alzheimer's disease research.</p>Formula:C23H17N3O4Color and Shape:SolidMolecular weight:399.399WAY-606344
CAS:<p>WAY-606344 (Compound 97) is an inhibitor of Casein kinase 1δ and shows potential for Alzheimer's disease research.</p>Formula:C14H8ClN3O2Color and Shape:SolidMolecular weight:285.685
