Casein Kinase
Casein kinases are a family of serine/threonine protein kinases that regulate various cellular processes, including DNA repair, circadian rhythms, and signal transduction. These kinases are involved in the phosphorylation of numerous proteins and are implicated in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. At CymitQuimica, we offer a selection of casein kinase inhibitors to support your research in signal transduction, cell cycle regulation, and therapeutic development.
Found 143 products for "Casein Kinase".
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IC261
CAS:IC261 (SU-5607) is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.Formula:C18H17NO4Purity:98.77% - 99.91%Color and Shape:SolidMolecular weight:311.33LY-294002 hydrochloride
CAS:LY-294002 HCl (NSC 697286) is a stable PI3K inhibitor (IC50: 0.5-0.97 µM) and prevents autophagosome formation.Formula:C19H17NO3·HClPurity:99.95% - 99.98%Color and Shape:Purple LiquidMolecular weight:343.81LH846
CAS:LH846 is a selective inhibitor of CK1δ (IC50 values are 290 nM, 1.3 uM and 2.5 uM for CK1δ, ε and α); exhibits no inhibitory activity at CK2.Formula:C16H13ClN2OSPurity:90% - 98.26%Color and Shape:SolidMolecular weight:316.81PF-4800567
CAS:PF-4800567 is a selective inhibitor of casein kinase 1ε (CK1ε; IC50 = 32 nM) with greater than 20-fold selectivity over CK1δ.Formula:C17H18ClN5O2Purity:99.74% - 99.76%Color and Shape:White SolidMolecular weight:359.81Orobol
CAS:Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover.Formula:C15H10O6Purity:98% - 98%Color and Shape:SolidMolecular weight:286.24XL413
CAS:XL-413 is an oral CDC7 kinase inhibitor, potentially blocking DNA replication, mitosis, and cancer cell growth.Formula:C14H12ClN3O2Purity:98.40% - 99.94%Color and Shape:SolidMolecular weight:289.72CK2-IN-9
CAS:CK2-IN-9, a potent and selective CK2 kinase inhibitor, exhibits an inhibitory concentration (IC50) of 3 nM against its target enzyme and hampers Wnt reporterFormula:C23H29N9OColor and Shape:SolidMolecular weight:447.54BTX161
CAS:BTX161: potent CKIα degrader, surpasses Lenalidomide in AML, triggers DDR + p53, stabilizes MDM2.Formula:C15H16N2O3Color and Shape:SolidMolecular weight:272.3SR-1277
CAS:SR-1277 is a potent, highly selective and ATP-competitive CK1δ/ε inhibitor, regulating Wee1 activity at the G2/M cell-cycle interface, and antiproliferative.Formula:C21H19N9O3SColor and Shape:SolidMolecular weight:477.5AMG-548
CAS:AMG-548, oral p38α inhibitor (Ki=0.5 nM), >1000x selectivity over p38γ/δ, blocks TNFα (IC50=3 nM), also inhibits Wnt/Casein kinase 1δ/ε.Formula:C29H27N5OPurity:99.91%Color and Shape:SolidMolecular weight:461.56SSTC3
CAS:SSTC3 is a casein kinase 1α (CK1α) activator with potential antitumor activity that inhibits WNT signaling.Formula:C23H17F3N4O3S2Purity:98.65% - 99.94%Color and Shape:SolidMolecular weight:518.53Ref: TM-T13004
1mg94.00€5mg222.00€1mL*10mM (DMSO)225.00€10mg356.00€25mg583.00€50mg820.00€100mg1,099.00€CK2/PIM1-IN-1
CAS:CK2/PIM1-IN-1 inhibits CK2 & PIM1 (IC50s: 3.787 & 4.327 μM), aimed for cancer research.Formula:C15H9NO4S2Purity:98%Color and Shape:SolidMolecular weight:331.37SRPIN-803
CAS:SRPIN-803 is a selective dual SRPK1 and CK2 inhibitor.Formula:C14H9F3N4O3SPurity:98%Color and Shape:SolidMolecular weight:370.31Umbralisib tosylate
CAS:Umbralisib tosylate, an oral PI3Kδ/CK1ε inhibitor (EC50: 22.2 nM/6.0 μM), shows promise for CLL research.Formula:C38H32F3N5O6SColor and Shape:SolidMolecular weight:743.75TMCB
CAS:CK2 and ERK8 inhibitorFormula:C11H9Br4N3O2Purity:98%Color and Shape:SolidMolecular weight:534.82Quinalizarin
CAS:Quinalizarin, the most selective CK2 inhibitor, is superior to CX-4945 which is the first-in-class CK2 inhibitor.Formula:C14H8O6Purity:98%Color and Shape:SolidMolecular weight:272.21HDAC/CK2-IN-1
CAS:HDAC/CK2-IN-1 (compound 38) acts as an inhibitor of HDAC1 (IC 50 = 1.46 μM), HDAC6 (IC 50 = 0.66 μM), and CK2 (IC 50 = 3.67 μM). It demonstrates promising antiproliferative effects on various cell lines, including Jurkat, MCF-7, HCT-116, and HL-60.Formula:C15H18Br4N4O2Color and Shape:SolidMolecular weight:605.95CK1-IN-2
CAS:CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor p38a, and is used in DUX4 overexpression-associated diseases, such as muscular dystrophy.Formula:C17H12FN3O2Purity:99.31%Color and Shape:SolidMolecular weight:309.29Tyrphostin AG 1112
CAS:Tyrphostin AG 1112 is a Bcr-Abl kinase blocker. It can activate the terminal differentiation of K562 cells and the purging of Ph+ cells.Formula:C15H10N6Color and Shape:SolidMolecular weight:274.28PF 4800567 hydrochloride
CAS:casein kinase 1ε inhibitorFormula:C17H19Cl2N5O2Purity:98%Color and Shape:SolidMolecular weight:396.27
