Retinoid Receptor
Retinoid Receptors are nuclear receptors that mediate the effects of retinoids (vitamin A derivatives) on gene expression. These receptors play a vital role in cell differentiation, proliferation, and apoptosis. Inhibitors of retinoid receptors are used to study their involvement in various diseases, including cancer, skin disorders, and metabolic conditions. By modulating retinoid receptor activity, these inhibitors can provide insights into the mechanisms of retinoid signaling and its therapeutic potential. At CymitQuimica, we provide retinoid receptor inhibitors to support your research in dermatology, oncology, and metabolic regulation.
Found 20 products of "Retinoid Receptor"
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BMS 195614
CAS:BMS 195614 (BMS614) is a selective RARα antagonist. BMS 195614 can bind to the RARα subunit.Formula:C29H24N2O3Purity:97.14%Color and Shape:SolidMolecular weight:448.51CD3254
CAS:CD3254 is a selective and potent retinoid X receptor-like (RXR) agonist that inhibits neuronal cell death with OGD/reoxygenation.Formula:C24H28O3Purity:98.71% - 98.71%Color and Shape:SolidMolecular weight:364.48AR7
CAS:AR7 is a retinoic acid receptor α (RARα) antagonist.Formula:C15H12ClNOPurity:98.12% - 99.86%Color and Shape:SolidMolecular weight:257.71Ref: TM-T3955
1mg37.00€5mg69.00€10mg96.00€25mg202.00€50mg329.00€100mg550.00€200mg758.00€500mg1,159.00€1mL*10mM (DMSO)74.00€Fenretinide
CAS:Fenretinide (4-HPR) is an orally-active synthetic retinoid derivative with potential antineoplastic and chemopreventive activities.Formula:C26H33NO2Purity:98% - 99.68%Color and Shape:Yellow PowderMolecular weight:391.55palovarotene
CAS:Palovarotene (Ro 3300074) is an agonist of nuclear retinoic acid receptor γ (RAR-γ).
Formula:C27H30N2O2Purity:97.88% - 98.05%Color and Shape:SolidMolecular weight:414.54trifarotene
CAS:Trifarotene (CD5789) is a RARγ agonist, 65x more selective than RARα and 16x than RARβ, with EC50 of 7.7 nM.
Formula:C29H33NO4Purity:99.51%Color and Shape:SolidMolecular weight:459.58CD2665
CAS:CD2665 is an orally active antagonist of retinoic acid receptor (RAR). For RARγ and RARβ, the Kis are 110 nM and 306 nM.Formula:C31H34O5Purity:99.71%Color and Shape:SolidMolecular weight:486.6BMS270394
CAS:BMS270394 is a RARγ agonist used in the study of breast cancer and skin diseases.Formula:C23H26FNO4Color and Shape:SolidMolecular weight:399.46Fluorobexarotene
CAS:Fluorobexarotene, a potent RXR agonist, has 75% higher affinity than Bexarotene with Ki of 12 nM and EC50 of 43 nM for RXRα.Formula:C24H27FO2Purity:99.08%Color and Shape:SolidMolecular weight:366.47Ref: TM-T11303
1mg170.00€5mg416.00€10mg615.00€25mg964.00€50mg1,305.00€100mg1,755.00€500mg3,501.00€1mL*10mM (DMSO)335.00€AC-261066
CAS:AC-261066 is an orally available and isoform-selective agonist of RARβ2 with a pEC50 of 8.0.Formula:C17H20FNO4SPurity:99.64%Color and Shape:SolidMolecular weight:353.41MM 11253
CAS:MM 11253 is a RARγ antagonist with IC50 of 44nM.Formula:C28H30O2S2Purity:99.41%Color and Shape:SolidMolecular weight:462.67Ch55
CAS:Ch55, a potent HL60 cell differentiator (EC50=200nM), binds well to RAR-α/β, useful for cancer research.Formula:C24H28O3Purity:99.55%Color and Shape:SolidMolecular weight:364.48Ref: TM-T14946
1mg39.00€5mg82.00€10mg117.00€25mg240.00€50mg374.00€100mg580.00€200mg798.00€1mL*10mM (DMSO)89.00€AGN 196996
CAS:AGN 196996: strong RARα inhibitor (Ki: 2 nM), weak for RARβ/γ (Ki: 1087/8523 nM).Formula:C24H20BrNO5Purity:99.94%Color and Shape:SolidMolecular weight:482.32Ref: TM-T10261
1mg59.00€5mg131.00€10mg190.00€25mg329.00€50mg477.00€100mg702.00€1mL*10mM (DMSO)138.00€BMS 753
CAS:BMS 753 is an agonist of isotype-selective retinoic acid receptor α (RARα, Ki= 2 nM).Formula:C21H21NO4Purity:98.55%Color and Shape:SolidMolecular weight:351.4KCL-286
CAS:KCL-286 is an available and potent retinoic acid receptor beta agonist for the amelioration of spinal cord injury (SCI).Formula:C19H14N2O4Purity:99.93%Color and Shape:SolidMolecular weight:334.33BMS641
CAS:BMS641 (BMS-209641) is a RARβ agonist with affinity for RARβ that synergistically activates RARβ and RARgamma to induce cell maturation.Formula:C27H23ClO2Purity:98.11%Color and Shape:SolidMolecular weight:414.92Ref: TM-T26854
1mg88.00€5mg215.00€10mg358.00€25mg692.00€50mg982.00€100mg1,333.00€200mg1,791.00€1mL*10mM (DMSO)235.00€ER 50891
CAS:ER-50891 is a potent RARα antagonist, countering retinoic acid inhibition and aiding BMP2-induced osteoblast differentiation.Formula:C29H24N2O2Purity:99.43%Color and Shape:SolidMolecular weight:432.51LE135
CAS:LE135: RARα/RARβ antagonist (Ki: 1.4 μM/220 nM), favors RARβ, selective vs RARγ/RXRs; also activates TRPV1/TRPA1 (EC50s: 2.5/20 μM).Formula:C29H30N2O2Purity:97.94%Color and Shape:SolidMolecular weight:438.56Ref: TM-T22920
1mg44.00€2mg58.00€5mg96.00€10mg128.00€25mg207.00€50mg308.00€100mg447.00€1mL*10mM (DMSO)92.00€ZSH-2208
CAS:ZSH-2208 is a retinoic acid A analogue that inhibits tumour cell proliferation and survival through RARγ-TNFAIP3 and retinoid receptors.Formula:C20H18O3SPurity:99.81%Color and Shape:SolidMolecular weight:338.42BMS453
CAS:BMS453 (BMS-189453), a synthetic retinoid, is a potent and selective agonist of RARβ and a potent testicular toxin.Formula:C27H24O2Purity:99.93%Color and Shape:SolidMolecular weight:380.48
