Retinoid Receptor
Retinoid Receptors are nuclear receptors that mediate the effects of retinoids (vitamin A derivatives) on gene expression. These receptors play a vital role in cell differentiation, proliferation, and apoptosis. Inhibitors of retinoid receptors are used to study their involvement in various diseases, including cancer, skin disorders, and metabolic conditions. By modulating retinoid receptor activity, these inhibitors can provide insights into the mechanisms of retinoid signaling and its therapeutic potential. At CymitQuimica, we provide retinoid receptor inhibitors to support your research in dermatology, oncology, and metabolic regulation.
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LG-100064
CAS:153559-46-7
LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM …
Formula:
C23H26O3
Purity:
98.65%
Color and Shape:
Solid
Molecular weight:
350.45
Ref: TM-T11844
| 2mg | 46.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 171.00 € | ||
| 50mg | 246.00 € | ||
| 100mg | 365.00 € | ||
| 200mg | 538.00 € | ||
| 1mL*10mM (DMSO) | 76.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Isotretinoin
CAS:4759-48-2
Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve …
Formula:
C20H28O2
Purity:
98.06% - 99.61%
Color and Shape:
Reddish-Orange Plates From Isopropyl Alcohol (Ntp 1992)
Molecular weight:
300.44
Ref: TM-T1611
| 50mg | 47.00 € | ||
| 100mg | 59.00 € | ||
| 200mg | 77.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Etodolac
CAS:41340-25-4
Etodolac (AY-24236), a pyranocarboxylic NSAID, blocks COX-1/2, reducing pain, fever, inflammation, and inhibits platelet aggregation.
Formula:
C17H21NO3
Purity:
99.84% - 99.92%
Color and Shape:
Crystalline Solid
Molecular weight:
287.35
Ref: TM-T1002
| 25mg | 45.00 € | ||
| 50mg | 57.00 € | ||
| 100mg | 78.00 € | ||
| 200mg | 99.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Mofarotene
CAS:125533-88-2
Mofarotene (Ro-40-8757) is a small molecule compound that shows considerable antitumor activity in many cancer …
Formula:
C29H39NO2
Purity:
99.36%
Color and Shape:
Liquid
Molecular weight:
433.63
Ref: TM-T68104
| 1mg | 105.00 € | ||
| 5mg | 253.00 € | ||
| 10mg | 372.00 € | ||
| 25mg | 620.00 € | ||
| 50mg | 881.00 € | ||
| 100mg | 1,197.00 € | ||
| 500mg | 2,396.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
BMS 195614
CAS:253310-42-8
BMS 195614 (BMS614) is a selective RARα antagonist. BMS 195614 can bind to the RARα …
Formula:
C29H24N2O3
Purity:
97.7%
Color and Shape:
Solid
Molecular weight:
448.51
Ref: TM-T22192
| 1mg | 169.00 € | ||
| 5mg | 389.00 € | ||
| 10mg | 575.00 € | ||
| 25mg | 917.00 € | ||
| 50mg | 1,235.00 € | ||
| 100mg | 1,654.00 € | ||
| 500mg | 3,325.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
CD3254
CAS:196961-43-0
CD3254 is a selective and potent retinoid X receptor-like (RXR) agonist that inhibits neuronal cell …
Formula:
C24H28O3
Purity:
98.71% - 98.71%
Color and Shape:
Solid
Molecular weight:
364.48
Ref: TM-T14912
| 1mg | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CD437
CAS:125316-60-1
CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.
Formula:
C27H26O3
Purity:
98.79% - 99.63%
Color and Shape:
Solid
Molecular weight:
398.49
Ref: TM-T4371
| 2mg | 40.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 291.00 € | ||
| 100mg | 477.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AGN 193109
CAS:171746-21-7
AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 …
Formula:
C28H24O2
Purity:
98.81% - 99.89%
Color and Shape:
Solid
Molecular weight:
392.49
Ref: TM-TQ0097
| 1mg | 67.00 € | ||
| 2mg | 89.00 € | ||
| 5mg | 150.00 € | ||
| 10mg | 231.00 € | ||
| 25mg | 463.00 € | ||
| 50mg | 674.00 € | ||
| 100mg | 916.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
UVI 3003
CAS:847239-17-2
UVI 3003 blocks retinoid X receptor (RXRα) in Xenopus/human Cos7 cells; IC50: 0.22/0.24 μM.
Formula:
C28H36O4
Purity:
99.94%
Color and Shape:
Solid
Molecular weight:
436.58
Ref: TM-T17209
| 1mg | 35.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 237.00 € | ||
| 50mg | 398.00 € | ||
| 100mg | 594.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AR7
CAS:80306-38-3
AR7 is a retinoic acid receptor α (RARα) antagonist.
Formula:
C15H12ClNO
Purity:
98.12% - 99.52%
Color and Shape:
Solid
Molecular weight:
257.71
Ref: TM-T3955
| 1mg | 36.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 99.00 € | ||
| 25mg | 203.00 € | ||
| 50mg | 329.00 € | ||
| 100mg | 544.00 € | ||
| 200mg | 741.00 € | ||
| 500mg | 1,133.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Bexarotene
CAS:153559-49-0
Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of …
Formula:
C24H28O2
Purity:
98.12% - 99%
Color and Shape:
White Solid
Molecular weight:
348.48
Ref: TM-T6410
| 10mg | 35.00 € | ||
| 25mg | 52.00 € | ||
| 50mg | 67.00 € | ||
| 100mg | 88.00 € | ||
| 200mg | 119.00 € | ||
| 500mg | 243.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
palovarotene
CAS:410528-02-8
Palovarotene (Ro 3300074) is an agonist of nuclear retinoic acid receptor γ (RAR-γ).
Formula:
C27H30N2O2
Purity:
96.89% - 98.05%
Color and Shape:
Solid
Molecular weight:
414.54
Ref: TM-T4538
| 1mg | 39.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 246.00 € | ||
| 50mg | 392.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
trifarotene
CAS:895542-09-3
Trifarotene (CD5789) is a RARγ agonist, 65x more selective than RARα and 16x than RARβ, …
Formula:
C29H33NO4
Purity:
99.78%
Color and Shape:
Solid
Molecular weight:
459.58
Ref: TM-T7586
| 5mg | 41.00 € | ||
| 10mg | 63.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 171.00 € | ||
| 100mg | 276.00 € | ||
| 200mg | 401.00 € | ||
| 1mL*10mM (DMSO) | 41.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Tarenflurbil
CAS:51543-40-9
Tarenflurbil, the R-enantiomer of flurbiprofen, lacks COX inhibition and was tested for Alzheimer's treatment.
Formula:
C15H13FO2
Purity:
100% - 98%
Color and Shape:
Solid
Molecular weight:
244.26
Ref: TM-T5843
| 100mg | 59.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AM580
CAS:102121-60-8
AM580 (CD336) is a retinoic acid receptor agonist that is selective for RARα( IC50 : …
Formula:
C22H25NO3
Purity:
98% - 99.89%
Color and Shape:
Solid
Molecular weight:
351.44
Ref: TM-T5854
| 2mg | 39.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 161.00 € | ||
| 50mg | 310.00 € | ||
| 100mg | 458.00 € | ||
| 500mg | 1,044.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
HX 531
CAS:188844-34-0
HX 531 is a RXR antagonist (IC50 of 18 nM).Cost-effective and quality-assured.
Formula:
C29H29N3O4
Purity:
98.59% - 99.43%
Color and Shape:
Solid
Molecular weight:
483.56
Ref: TM-T22843
| 1mg | 46.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 252.00 € | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Tazarotene
CAS:118292-40-3
Tazarotene (Zorac), a synthetic topical retinoid, treats psoriasis by normalizing keratinocytes and reducing growth.
Formula:
C21H21NO2S
Purity:
97.01% - 99.14%
Color and Shape:
White Solid
Molecular weight:
351.46
Ref: TM-T6696
| 5mg | 38.00 € | ||
| 10mg | 49.00 € | ||
| 25mg | 87.00 € | ||
| 50mg | 145.00 € | ||
| 100mg | 251.00 € | ||
| 200mg | 326.00 € | ||
| 500mg | 551.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Fenretinide
CAS:65646-68-6
Fenretinide (4-HPR) is an orally-active synthetic retinoid derivative with potential antineoplastic and chemopreventive activities.
Formula:
C26H33NO2
Purity:
98% - 99.72%
Color and Shape:
Yellow Powder
Molecular weight:
391.55
Ref: TM-T1872
| 5mg | 40.00 € | ||
| 10mg | 58.00 € | ||
| 25mg | 85.00 € | ||
| 50mg | 95.00 € | ||
| 100mg | 124.00 € | ||
| 200mg | 180.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BMS 753
CAS:215307-86-1
BMS 753 is an agonist of isotype-selective retinoic acid receptor α (RARα, Ki= 2 nM).
Formula:
C21H21NO4
Purity:
98.4%
Color and Shape:
Solid
Molecular weight:
351.4
Ref: TM-T22049
| 5mg | 63.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 208.00 € | ||
| 50mg | 334.00 € | ||
| 100mg | 463.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
LY 178002
CAS:107889-32-7
LY 178002 inhibits 5-LPO (IC50: 0.6 μM), PLA2, and LTB4 production; weak on cyclooxygenase.
Formula:
C18H25NO2S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
319.46
Ref: TM-T15825
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
