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Retinoid Receptor

Retinoid Receptor

Retinoid Receptors are nuclear receptors that mediate the effects of retinoids (vitamin A derivatives) on gene expression. These receptors play a vital role in cell differentiation, proliferation, and apoptosis. Inhibitors of retinoid receptors are used to study their involvement in various diseases, including cancer, skin disorders, and metabolic conditions. By modulating retinoid receptor activity, these inhibitors can provide insights into the mechanisms of retinoid signaling and its therapeutic potential. At CymitQuimica, we provide retinoid receptor inhibitors to support your research in dermatology, oncology, and metabolic regulation.

Found 29 products of "Retinoid Receptor"

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  • MM 11253

    CAS:
    <p>MM 11253 is a RARγ antagonist with IC50 of 44nM.</p>
    Formula:C28H30O2S2
    Purity:99.41%
    Color and Shape:Solid
    Molecular weight:462.67
  • AC-261066

    CAS:
    <p>AC-261066 is an orally available and isoform-selective agonist of RARβ2 with a pEC50 of 8.0.</p>
    Formula:C17H20FNO4S
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:353.41
  • BMS641

    CAS:
    <p>BMS641 (BMS-209641) is a RARβ agonist with affinity for RARβ that synergistically activates RARβ and RARgamma to induce cell maturation.</p>
    Formula:C27H23ClO2
    Purity:98.98%
    Color and Shape:Solid
    Molecular weight:414.92
  • KCL-286

    CAS:
    <p>KCL-286 is an available and potent retinoic acid receptor beta agonist for the amelioration of spinal cord injury (SCI).</p>
    Formula:C19H14N2O4
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:334.33
  • ER 50891

    CAS:
    <p>ER-50891 is a potent RARα antagonist, countering retinoic acid inhibition and aiding BMP2-induced osteoblast differentiation.</p>
    Formula:C29H24N2O2
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:432.51
  • LE135

    CAS:
    <p>LE135: RARα/RARβ antagonist (Ki: 1.4 μM/220 nM), favors RARβ, selective vs RARγ/RXRs; also activates TRPV1/TRPA1 (EC50s: 2.5/20 μM).</p>
    Formula:C29H30N2O2
    Purity:97.94%
    Color and Shape:Solid
    Molecular weight:438.56
  • PA452

    CAS:
    <p>PA452 is a selective antagonist of retinoic X receptor (RXR) and suppresses the effect of Retinoic acid on Th1/Th2 development.</p>
    Formula:C26H37N3O3
    Purity:97.14%
    Color and Shape:Solid
    Molecular weight:439.59
  • ZSH-2208

    CAS:
    <p>ZSH-2208 is a retinoic acid A analogue that inhibits tumour cell proliferation and survival through RARγ-TNFAIP3 and retinoid receptors.</p>
    Formula:C20H18O3S
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:338.42
  • BMS453

    CAS:
    <p>BMS453 (BMS-189453), a synthetic retinoid, is a potent and selective agonist of RARβ and a potent testicular toxin.</p>
    Formula:C27H24O2
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:380.48