Retinoid Receptor
Retinoid Receptors are nuclear receptors that mediate the effects of retinoids (vitamin A derivatives) on gene expression. These receptors play a vital role in cell differentiation, proliferation, and apoptosis. Inhibitors of retinoid receptors are used to study their involvement in various diseases, including cancer, skin disorders, and metabolic conditions. By modulating retinoid receptor activity, these inhibitors can provide insights into the mechanisms of retinoid signaling and its therapeutic potential. At CymitQuimica, we provide retinoid receptor inhibitors to support your research in dermatology, oncology, and metabolic regulation.
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AGN 196996
CAS:958295-17-5
AGN 196996: strong RARα inhibitor (Ki: 2 nM), weak for RARβ/γ (Ki: 1087/8523 nM).
Formula:
C24H20BrNO5
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
482.32
Ref: TM-T10261
| 1mg | 87.00 € | ||
| 5mg | 206.00 € | ||
| 10mg | 309.00 € | ||
| 25mg | 535.00 € | ||
| 50mg | 778.00 € | ||
| 100mg | 1,141.00 € | ||
| 1mL*10mM (DMSO) | 218.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
BMS270394
CAS:262433-54-5
BMS270394 is a RARγ agonist used in the study of breast cancer and skin diseases.
Formula:
C23H26FNO4
Color and Shape:
Solid
Molecular weight:
399.46
Ref: TM-T26846
| 1mg | 374.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
AC-261066
CAS:870773-76-5
AC-261066 is an orally available and isoform-selective agonist of RARβ2 with a pEC50 of 8.0.
Formula:
C17H20FNO4S
Purity:
98.44%
Color and Shape:
Solid
Molecular weight:
353.41
Ref: TM-T14089
| 1mg | 35.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 221.00 € | ||
| 50mg | 328.00 € | ||
| 100mg | 460.00 € | ||
| 1mL*10mM (DMSO) | 76.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
CD 1530
CAS:107430-66-0
CD 1530 is an ARγ agonist (Kd:150 nM) with potential anticancer activity for the study …
Formula:
C27H26O3
Purity:
98.13%
Color and Shape:
Solid
Molecular weight:
398.49
Ref: TM-T21686
| 1mg | 76.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
MM 11253
CAS:345952-44-5
MM 11253 is a RARγ antagonist with IC50 of 44nM.
Formula:
C28H30O2S2
Purity:
98.62%
Color and Shape:
Solid
Molecular weight:
462.67
Ref: TM-T23005
| 1mg | 40.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 269.00 € | ||
| 50mg | 425.00 € | ||
| 100mg | 625.00 € | ||
| 1mL*10mM (DMSO) | 90.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
K-8012
CAS:1346513-17-4
K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an …
Formula:
C23H23FN4
Purity:
98.24%
Color and Shape:
Solid
Molecular weight:
374.45
Ref: TM-T24240
| 1mg | 113.00 € | ||
| 5mg | 250.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 551.00 € | ||
| 50mg | 771.00 € | ||
| 100mg | 1,052.00 € | ||
| 500mg | 2,112.00 € | ||
| 1mL*10mM (DMSO) | 266.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
AC-55649
CAS:59662-49-6
AC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of …
Formula:
C21H26O2
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
310.43
Ref: TM-T14090
| 5mg | 63.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 174.00 € | ||
| 50mg | 255.00 € | ||
| 100mg | 367.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
Ch55
CAS:110368-33-7
Ch55, a potent HL60 cell differentiator (EC50=200nM), binds well to RAR-α/β, useful for cancer research.
Formula:
C24H28O3
Purity:
99.01%
Color and Shape:
Solid
Molecular weight:
364.48
Ref: TM-T14946
| 1mg | 48.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 145.00 € | ||
| 25mg | 272.00 € | ||
| 50mg | 497.00 € | ||
| 100mg | 722.00 € | ||
| 500mg | 1,472.00 € | ||
| 1mL*10mM (DMSO) | 105.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
CD2665
CAS:170355-78-9
CD2665 is an orally active antagonist of retinoic acid receptor (RAR). For RARγ and RARβ, …
Formula:
C31H34O5
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
486.6
Ref: TM-T14911
| 1mg | 89.00 € | ||
| 5mg | 161.00 € | ||
| 10mg | 235.00 € | ||
| 25mg | 395.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 185.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
Fluorobexarotene
CAS:1190848-23-7
Fluorobexarotene, a potent RXR agonist, has 75% higher affinity than Bexarotene with Ki of 12 …
Formula:
C24H27FO2
Purity:
99.23%
Color and Shape:
Solid
Molecular weight:
366.47
Ref: TM-T11303
| 1mg | 170.00 € | ||
| 5mg | 430.00 € | ||
| 10mg | 634.00 € | ||
| 25mg | 1,000.00 € | ||
| 50mg | 1,346.00 € | ||
| 100mg | 1,822.00 € | ||
| 500mg | 3,626.00 € | ||
| 1mL*10mM (DMSO) | 352.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
BMS641
CAS:369364-50-1
BMS641 (BMS-209641) is a RARβ agonist with affinity for RARβ that synergistically activates RARβ and …
Formula:
C27H23ClO2
Purity:
98.98%
Color and Shape:
Solid
Molecular weight:
414.92
Ref: TM-T26854
| 1mg | 156.00 € | ||
| 5mg | 368.00 € | ||
| 10mg | 615.00 € | ||
| 25mg | 1,189.00 € | ||
| 50mg | 1,699.00 € | ||
| 100mg | 2,308.00 € | ||
| 1mL*10mM (DMSO) | 412.00 € |
Estimated delivery in United States, on Tuesday 11 Feb 2025
ER 50891
CAS:187400-85-7
ER-50891 is a potent RARα antagonist, countering retinoic acid inhibition and aiding BMP2-induced osteoblast differentiation.
Formula:
C29H24N2O2
Purity:
99.49%
Color and Shape:
Solid
Molecular weight:
432.51
Ref: TM-T22767
| 1mg | 158.00 € | ||
| 5mg | 411.00 € | ||
| 10mg | 537.00 € | ||
| 25mg | 861.00 € | ||
| 50mg | 1,170.00 € | ||
| 100mg | 1,566.00 € | ||
| 200mg | 2,127.00 € |
Estimated delivery in United States, on Tuesday 11 Feb 2025
AGN 194310
CAS:229961-45-9
AGN 194310 (VTP-194310) is retinioic acid receptors (RARs) pan-antagonist. The Kd values of 3 nM, …
Formula:
C28H24O2S
Color and Shape:
Solid
Molecular weight:
424.55
Ref: TM-T14143
| 5mg | 558.00 € | ||
| 25mg | 1,586.00 € | ||
| 50mg | 2,088.00 € | ||
| 100mg | 3,173.00 € |
Estimated delivery in United States, on Tuesday 11 Feb 2025
KCL-286
CAS:1952276-71-9
KCL-286 is an available and potent retinoic acid receptor beta agonist for the amelioration of …
Formula:
C19H14N2O4
Purity:
99.93%
Color and Shape:
Liquid
Molecular weight:
334.33
Ref: TM-T78575
| 1mg | 88.00 € | ||
| 5mg | 185.00 € | ||
| 10mg | 299.00 € | ||
| 25mg | 627.00 € | ||
| 50mg | 1,004.00 € | ||
| 100mg | 1,360.00 € | ||
| 200mg | 1,829.00 € |
Estimated delivery in United States, on Tuesday 11 Feb 2025
LE135
CAS:155877-83-1
LE135: RARα/RARβ antagonist (Ki: 1.4 μM/220 nM), favors RARβ, selective vs RARγ/RXRs; also activates TRPV1/TRPA1 …
Formula:
C29H30N2O2
Purity:
98.33%
Color and Shape:
Solid
Molecular weight:
438.56
Ref: TM-T22920
| 1mg | 46.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 133.00 € | ||
| 25mg | 213.00 € | ||
| 50mg | 318.00 € | ||
| 100mg | 462.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 11 Feb 2025
PA452
CAS:457657-34-0
PA452 is a selective antagonist of retinoic X receptor (RXR) and suppresses the effect of …
Formula:
C26H37N3O3
Purity:
96.76%
Color and Shape:
Solid
Molecular weight:
439.59
Ref: TM-T16425
| 1mg | 91.00 € | ||
| 5mg | 247.00 € | ||
| 10mg | 397.00 € | ||
| 25mg | 649.00 € | ||
| 50mg | 925.00 € | ||
| 100mg | 1,266.00 € | ||
| 1mL*10mM (DMSO) | 271.00 € |
Estimated delivery in United States, on Tuesday 11 Feb 2025
BMS453
CAS:166977-43-1
BMS453 (BMS-189453), a synthetic retinoid, is a potent and selective agonist of RARβ and a …
Formula:
C27H24O2
Purity:
99.78%
Color and Shape:
Solid
Molecular weight:
380.48
Ref: TM-T21714
| 5mg | 63.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 203.00 € | ||
| 50mg | 303.00 € | ||
| 100mg | 437.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
