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HIF/HIF Prolyl-Hydroxylase

HIF/HIF Prolyl-Hydroxylase

Hypoxia-Inducible Factor (HIF) is a transcription factor that plays a critical role in cellular responses to low oxygen levels (hypoxia). HIF activity is tightly regulated by HIF prolyl-hydroxylases, which target HIF for degradation under normoxic conditions. Inhibitors of HIF prolyl-hydroxylase can stabilize HIF, promoting the expression of genes involved in angiogenesis, erythropoiesis, and metabolism. These inhibitors are of great interest in treating conditions such as anemia, ischemic diseases, and cancer. At CymitQuimica, we offer HIF/HIF prolyl-hydroxylase inhibitors to support your research in hypoxia biology, cancer therapy, and metabolic regulation.

Found 146 products of "HIF/HIF Prolyl-Hydroxylase"

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  • (Rac)-PT2399
    Targetmol
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    (Rac)-PT2399

    CAS:
    (Rac)-PT2399 is a potent and specific inhibitor of hypoxia-inducible factor 2a (HIF-2α)(IC50 of 0.01 μM).
    Formula:C17H10F5NO4S
    Color and Shape:Solid
    Molecular weight:419.32

    Ref: TM-T12675

    5mg
    313.00€
    25mg
    888.00€
    50mg
    1,224.00€
    100mg
    1,972.00€
  • PHD2-IN-4
    Targetmol
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    PHD2-IN-4

    CAS:
    PHD2-IN-4 (compound 1) is an inhibitor of PHD2, with an IC50 of 4 nM. It is utilized in research related to chronic kidney disease.
    Formula:C21H19N5O3
    Color and Shape:Solid
    Molecular weight:389.407

    Ref: TM-T205562

    10mg
    To inquire
    50mg
    To inquire
  • CymitQuimica logo
    Targetmol
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    HIF-1/2α-IN-1

    HIF-1/2α-IN-1, an orally active compound, functions as an inhibitor of HIF-2α.
    Formula:C17H16N6O4
    Color and Shape:Solid
    Molecular weight:368.35

    Ref: TM-T61442

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • DS44470011
    Targetmol
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    DS44470011

    CAS:
    DS44470011 is an inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PHD) with oral bioavailability. It enhances the release of erythropoietin (EPO) from cells and is utilized in research related to renal anemia.
    Formula:C21H19N3O4
    Color and Shape:Solid
    Molecular weight:377.39

    Ref: TM-T88182

    10mg
    To inquire
    50mg
    To inquire
  • HIF-PHD-IN-1
    Targetmol
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    HIF-PHD-IN-1

    CAS:
    HIF-PHD-IN-1 is a pharmacological compound that acts as an orally active inhibitor of the hypoxia-inducible factor prolyl hydroxylase domain (HIF-PHD), displaying an IC50 of 54 nM for hHIF-PHD2. Its potential as a therapeutic agent for renal anemia is highly promising.
    Formula:C17H12Cl2N6O3
    Color and Shape:Solid
    Molecular weight:419.22

    Ref: TM-T39040

    ne
    Discontinued
    Discontinued product
  • Desidustat
    Targetmol
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    Desidustat

    CAS:

    Desidustat is an inhibitor of HIF hydroxylase.

    Formula:C16H16N2O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:332.31

    Ref: TM-T5176

    1mg
    Discontinued
    2mg
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    5mg
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    10mg
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    25mg
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    50mg
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    100mg
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    1ml*10 (DMSO)
    Discontinued
    Discontinued product