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Carbonic Anhydrase

Carbonic Anhydrase

Carbonic anhydrase is an enzyme that catalyzes the reversible conversion of carbon dioxide and water into bicarbonate and protons. This enzyme plays a crucial role in maintaining acid-base balance, respiration, and the transport of carbon dioxide in the blood. Inhibitors of carbonic anhydrase are used in the treatment of glaucoma, epilepsy, and altitude sickness, as well as in research on acid-base homeostasis and gas exchange. At CymitQuimica, we offer a range of high-quality carbonic anhydrase inhibitors and reagents to support your research in enzymology, respiratory physiology, and therapeutic development.

Found 177 products of "Carbonic Anhydrase"

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  • DPP IV/hCA II-IN-1

    CAS:
    <p>DPP IV/hCA II-IN-1: strong DPP IV &amp; CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).</p>
    Formula:C17H20N2O5S
    Color and Shape:Solid
    Molecular weight:364.42
  • CAIX/CAXII-IN-3


    <p>CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.</p>
    Color and Shape:Odour Solid
  • hCAII-IN-6


    <p>"hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."</p>
    Formula:C20H25N3O4S
    Color and Shape:Solid
    Molecular weight:403.5
  • CAIX Inhibitor S4

    CAS:
    <p>CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.</p>
    Formula:C15H17N3O4S
    Purity:99.07%
    Color and Shape:Solid
    Molecular weight:335.38
  • 2-Methoxy-4-propylphenol

    CAS:
    <p>2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.</p>
    Formula:C10H14O2
    Color and Shape:Solid
    Molecular weight:166.22
  • hCAIX-IN-17


    <p>hCA IX-IN-1 inhibits hCA I/II/IX/XII with Ki of 331.4/28.4/9.4/17.8 nM, has anticancer properties.</p>
    Formula:C19H18N2O3S
    Color and Shape:Solid
    Molecular weight:354.42
  • Dorzolamide

    CAS:
    <p>Dorzolamide is an anti-glaucoma agent and is a carbonic anhydrase inhibitor.</p>
    Formula:C10H16N2O4S3
    Purity:98%
    Color and Shape:White Or Almost White Crystalline Powder
    Molecular weight:324.44
  • 5,6-Dihydro-2H-pyran-2-one

    CAS:
    <p>5,6-Dihydro-2H-pyran-2-one is a carbonic anhydrase 1/9 inhibitor that inhibits KB cell viability.</p>
    Formula:C5H6O2
    Color and Shape:Solid
    Molecular weight:98.1
  • Carbonic anhydrase inhibitor 30


    <p>Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].</p>
    Formula:C23H22FN3O5S
    Color and Shape:Solid
    Molecular weight:471.12642
  • Chlorothiazide

    CAS:
    <p>Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.</p>
    Formula:C7H6ClN3O4S2
    Purity:98.46% - 98.91%
    Color and Shape:Crystals Physical Description Crystals; White Powder (Ntp 1992)
    Molecular weight:295.72
  • hCAI/II-IN-10


    <p>hCAI/II-IN-10 (Compound 5d) is an inhibitor of human carbonic anhydrase I and II (hCA I and hCA II), with IC50 values of 4.32 nM and 3.89 nM, respectively.</p>
    Formula:C24H17Cl2N3O3S2
    Color and Shape:Solid
    Molecular weight:530.446
  • CAIX/CAXII-IN-4


    <p>CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.</p>
    Formula:C23H21N5O3S
    Color and Shape:Solid
    Molecular weight:447.51
  • hCA/VEGFR-2-IN-3


    <p>hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2.</p>
    Formula:C24H28N6O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:528.58
  • Carbonic anhydrase inhibitor 32


    <p>Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.</p>
    Formula:C17H16N6O3S
    Color and Shape:Solid
    Molecular weight:384.41
  • Pyrocatechol

    CAS:
    <p>Pyrocatechol, often known as catechol or benzene-1,2-diol, is a benzenediol, Pyrocatechol was produced at a large scale industrially, mainly as precursors to pesticides, flavors, and fragrances. Its sulfonic acid is often present in the urine of many mammals.</p>
    Formula:C6H6O2
    Color and Shape:Solid
    Molecular weight:110.11
  • hCAIX/XII-IN-14


    <p>hCAIX/XII-IN-14 (Compound 1i) is an inhibitor of hCAIX and hCAXII, with Ki values of 9.4 nM for hCAII, 5.6 nM for hCAIX, and 6.3 nM for hCAXII.</p>
    Formula:C16H14F3N3O4S
    Color and Shape:Solid
    Molecular weight:401.36
  • hCAIX-IN-19


    <p>hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/</p>
    Color and Shape:Odour Solid
  • hCA/VEGFR-2-IN-2


    <p>Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII and</p>
    Formula:C23H26N6O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:498.55
  • α-Pyrone

    CAS:
    <p>Alpha-Pyrone exhibits inhibitory activity against tyrosinase, carbonic anhydrase 1, and carbonic anhydrase 9</p>
    Formula:C5H4O2
    Color and Shape:Solid
    Molecular weight:96.08
  • hCAII-IN-8

    CAS:
    <p>Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.</p>
    Formula:C15H16N2O5S
    Purity:99.73%
    Color and Shape:Soild
    Molecular weight:336.36