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ROR

ROR

Retinoic Acid-Related Orphan Receptors (RORs) are nuclear receptors that regulate various physiological processes, including circadian rhythm, immune response, and metabolism. ROR inhibitors are of interest in the study of autoimmune diseases, metabolic disorders, and cancer, as they can modulate gene expression and influence cellular functions. At CymitQuimica, we offer ROR inhibitors to support your research in immunology, endocrinology, and oncology.

Found 49 products for "ROR".

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  • RORγt inverse agonist 32
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    RORγt inverse agonist 32

    CAS:
    RORγt inverse agonist 32 (compound b14) exhibits oral activity and can be utilized in inflammatory research studies.
    Formula:C24H28F3NO5S
    Color and Shape:Solid
    Molecular weight:499.54

    Ref: TM-T200887

  • JTE-151
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    JTE-151

    CAS:
    JTE-151, a RORγ inhibitor, suppresses the overactive immune response by inhibiting RORγ, which is linked to the activation of Th17 cells. This action positions JTE-151 as a potential candidate for autoimmune disease research [1].
    Formula:C28H37ClN2O4
    Molecular weight:501.06

    Ref: TM-T86775

  • LDR102
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    LDR102

    CAS:
    LDR102 (Compound 19h) is an inhibitor of receptor tyrosine kinase-like orphan receptor 1 (ROR1) with a Ki value of 0.10 μM.
    Formula:C33H27N5O3
    Purity:97.42% - 99.52%
    Color and Shape:Solid
    Molecular weight:541.6

    Ref: TM-T210170

  • Vimirogant
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    Vimirogant

    CAS:
    Vimirogant is a RORγ inhibitor (Ki: <100 nM).
    Formula:C27H35F3N4O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:552.65

    Ref: TM-T16787

  • RORγ-IN-2
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    RORγ-IN-2

    CAS:
    RORγ-IN-2 (Compound 22) is an inhibitor of RORγ, with a Ki value of 16.6 nM for hRORγ. It is useful for research in IL-17-dependent autoimmune diseases.
    Formula:C28H32F3N5O4S2
    Color and Shape:Solid
    Molecular weight:623.71

    Ref: TM-T204411

  • RORγt inhibitor 4
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    RORγt inhibitor 4

    CAS:
    RORγt inhibitor 4 (Compound 9a) is an orally active RORγt inhibitor capable of penetrating the central nervous system. It has been shown to improve experimental autoimmune encephalomyelitis.
    Formula:C22H16Cl2F3NO4S
    Color and Shape:Solid
    Molecular weight:518.333

    Ref: TM-T205045

  • RORγt inverse agonist 34
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    RORγt inverse agonist 34

    CAS:
    RORγt inverse agonist 34 (compound 5a) is an inverse agonist for RORγt, exhibiting an IC50 of 0.094 μM for the inhibition of RORγt-LBD. This compound is utilized in psoriasis research.
    Formula:C31H37N3O3S
    Color and Shape:Solid
    Molecular weight:531.709

    Ref: TM-T204288

  • Hexyl 4-hydroxybenzoate
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    Hexyl 4-hydroxybenzoate

    CAS:
    Hexyl 4-hydroxybenzoate (Hexylparaben) is an agonist of the retinoic acid-related orphan receptor RORγ(t) with an EC50 of 144 nM. It is applicable in the study of autoimmune diseases.
    Formula:C13H18O3
    Molecular weight:222.2802

    Ref: TM-T212551

  • TAK-828F
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    TAK-828F

    CAS:
    TAK-828F: potent, selective RORγt inverse agonist. Oral. IC50=1.9 nM; reporter gene IC50=6.1 nM.
    Formula:C28H32FN3O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:509.57

    Ref: TM-T13067